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The map label for this gene is mshD

Identifier: 158317919

GI number: 158317919

Start: 7507093

End: 7508061

Strand: Direct

Name: mshD

Synonym: Franean1_6177

Alternate gene names: 158317919

Gene position: 7507093-7508061 (Clockwise)

Preceding gene: 158317918

Following gene: 158317921

Centisome position: 83.58

GC content: 74.2

Gene sequence:

>969_bases
GTGACCTCGCTGAGCTGGCTCCGCGCGCTCGATGTGGCCGACATCGCCGCCATCACCGACCTGCTGGCCGCGGCCGAGCG
GGCCGACGGCAACGGCGGCGTCTCCGAGGACGTCCGCCTCACCCTCCGCCCCGGCCCGGTCGGTGGCGGCGTGGAGCACC
TGGTCGCCCGCGCCGGCTCGGCTGTCGTCGGCTACGCGGCGCTCGGCGGCACGGCCACGGAGCGGCAGGCTGAGCTGGTT
GTCCATCCCGACCACCGCCGCAGGGGAGTCGGCACCGCGCTCGTCCACGCCCTCTTCGCGACGACGTCACCGGTCTCGTT
GAACATCTGGGCACACGGGGACACACCGGCCGCGGCCGCGCTGGCCACGCGCAACGGGTTCGACCGGGAGCGGGTGCTCC
TGCAGCTGCGCCGGCCCCTGGCTTCGGTCCGCCCCGGCGATCCGGATGATCTGCCAAGGCCCATCATCCCGGCCGACGTG
ACGATCCGGGCCTTCGAAGTGGGCGTGGATGAGGAGGCCTGGCTCGCCGTCAACGCCGAGGCCTTCGCCGACCACCCCGA
GCAGGGCCGCTGGACGCTGGACGACCTGCGTGCGCGGGAGGGCGAGCCCTGGTTCGACCCGGCCGGCTTCTTCCTCGCCG
AACGGAACGGCGCCCTGCTCGGCTTCCACTGGACCAAGGTGCACCCGCAGGACCCGGTACCCGAGCACCCCGCCGCGACG
GACCAGCCGGCCGGGCAACCAGGGCCGATCGGTGAGGTCTACGTCGTCGGCGTGGCCTCGGCGGCGGCGGGCACCGGGCT
GGGCGCGGCGTTGACGATCGTGGGTCTGCGGCACCTGCGCGACATCGGTCTGGCCTCGGTGATGCTCTACGTGGACGAGG
ACAACGCTCGCGCCGTCCGTCTCTACACGCGGCTCGGGTTCCGCCGGCACGCCGCCGATGTCTCCTACCGGCGCCCGGCG
CGCGGCTAG

Upstream 100 bases:

>100_bases
CGGCGCTTGTCACATTGACACCGGTACCGGGAAGATCGACATTCTGGGGAACGTCCTCGTGCCGGGCGAATGTCCGGCCC
GGACGCACTAACGTCGACTG

Downstream 100 bases:

>100_bases
GCCCGGTGCCGTGGATGGACACAGCGACGGGTCCGCTCAGGGGCCGGGCAGCTCAGGCTCCGCGGCGCGACACCACTCCC
GGCCACCGTTCCATGCCACG

Product: GCN5-like N-acetyltransferase

Products: NA

Alternate protein names: MSH acetyltransferase; Mycothiol synthase

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MTSLSWLRALDVADIAAITDLLAAAERADGNGGVSEDVRLTLRPGPVGGGVEHLVARAGSAVVGYAALGGTATERQAELV
VHPDHRRRGVGTALVHALFATTSPVSLNIWAHGDTPAAAALATRNGFDRERVLLQLRRPLASVRPGDPDDLPRPIIPADV
TIRAFEVGVDEEAWLAVNAEAFADHPEQGRWTLDDLRAREGEPWFDPAGFFLAERNGALLGFHWTKVHPQDPVPEHPAAT
DQPAGQPGPIGEVYVVGVASAAAGTGLGAALTIVGLRHLRDIGLASVMLYVDEDNARAVRLYTRLGFRRHAADVSYRRPA
RG

Sequences:

>Translated_322_residues
MTSLSWLRALDVADIAAITDLLAAAERADGNGGVSEDVRLTLRPGPVGGGVEHLVARAGSAVVGYAALGGTATERQAELV
VHPDHRRRGVGTALVHALFATTSPVSLNIWAHGDTPAAAALATRNGFDRERVLLQLRRPLASVRPGDPDDLPRPIIPADV
TIRAFEVGVDEEAWLAVNAEAFADHPEQGRWTLDDLRAREGEPWFDPAGFFLAERNGALLGFHWTKVHPQDPVPEHPAAT
DQPAGQPGPIGEVYVVGVASAAAGTGLGAALTIVGLRHLRDIGLASVMLYVDEDNARAVRLYTRLGFRRHAADVSYRRPA
RG
>Mature_321_residues
TSLSWLRALDVADIAAITDLLAAAERADGNGGVSEDVRLTLRPGPVGGGVEHLVARAGSAVVGYAALGGTATERQAELVV
HPDHRRRGVGTALVHALFATTSPVSLNIWAHGDTPAAAALATRNGFDRERVLLQLRRPLASVRPGDPDDLPRPIIPADVT
IRAFEVGVDEEAWLAVNAEAFADHPEQGRWTLDDLRAREGEPWFDPAGFFLAERNGALLGFHWTKVHPQDPVPEHPAATD
QPAGQPGPIGEVYVVGVASAAAGTGLGAALTIVGLRHLRDIGLASVMLYVDEDNARAVRLYTRLGFRRHAADVSYRRPAR
G

Specific function: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol

COG id: COG0456

COG function: function code R; Acetyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 N-acetyltransferase domains

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSHD_FRASN (A8LDL3)

Other databases:

- EMBL:   CP000820
- RefSeq:   YP_001510427.1
- ProteinModelPortal:   A8LDL3
- SMR:   A8LDL3
- GeneID:   5674498
- GenomeReviews:   CP000820_GR
- KEGG:   fre:Franean1_6177
- HOGENOM:   HBG292446
- OMA:   GFHWTKI
- ProtClustDB:   CLSK947767
- BioCyc:   FSP1855:FRANEAN1_6177-MONOMER
- HAMAP:   MF_01698
- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR017813
- Gene3D:   G3DSA:3.40.630.30
- TIGRFAMs:   TIGR03448

Pfam domain/function: PF00583 Acetyltransf_1; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.1.189

Molecular weight: Translated: 34273; Mature: 34142

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS51186 GNAT

Important sites: BINDING 36-36 BINDING 187-187 BINDING 226-226 BINDING 252-252 BINDING 290-290

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLSWLRALDVADIAAITDLLAAAERADGNGGVSEDVRLTLRPGPVGGGVEHLVARAGS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCC
AVVGYAALGGTATERQAELVVHPDHRRRGVGTALVHALFATTSPVSLNIWAHGDTPAAAA
CEEEEEHHCCCCCCCCEEEEECCCHHHCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHH
LATRNGFDRERVLLQLRRPLASVRPGDPDDLPRPIIPADVTIRAFEVGVDEEAWLAVNAE
HHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEHH
AFADHPEQGRWTLDDLRAREGEPWFDPAGFFLAERNGALLGFHWTKVHPQDPVPEHPAAT
HHCCCCCCCCEEHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEECCCCCCCCCCCCC
DQPAGQPGPIGEVYVVGVASAAAGTGLGAALTIVGLRHLRDIGLASVMLYVDEDNARAVR
CCCCCCCCCCCEEEEEEEEHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEE
LYTRLGFRRHAADVSYRRPARG
EEHHHCHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TSLSWLRALDVADIAAITDLLAAAERADGNGGVSEDVRLTLRPGPVGGGVEHLVARAGS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCC
AVVGYAALGGTATERQAELVVHPDHRRRGVGTALVHALFATTSPVSLNIWAHGDTPAAAA
CEEEEEHHCCCCCCCCEEEEECCCHHHCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHH
LATRNGFDRERVLLQLRRPLASVRPGDPDDLPRPIIPADVTIRAFEVGVDEEAWLAVNAE
HHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEHH
AFADHPEQGRWTLDDLRAREGEPWFDPAGFFLAERNGALLGFHWTKVHPQDPVPEHPAAT
HHCCCCCCCCEEHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEECCCCCCCCCCCCC
DQPAGQPGPIGEVYVVGVASAAAGTGLGAALTIVGLRHLRDIGLASVMLYVDEDNARAVR
CCCCCCCCCCCEEEEEEEEHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEE
LYTRLGFRRHAADVSYRRPARG
EEHHHCHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA