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The map label for this gene is mshA

Identifier: 158317904

GI number: 158317904

Start: 7495980

End: 7497284

Strand: Direct

Name: mshA

Synonym: Franean1_6162

Alternate gene names: 158317904

Gene position: 7495980-7497284 (Clockwise)

Preceding gene: 158317902

Following gene: 158317905

Centisome position: 83.46

GC content: 74.18

Gene sequence:

>1305_bases
GTGCATCTGGTCGGAGGCGCGCCGCCGGAACATCCCGAACCAGCCCGGCCGAAGCCAGCCTCGCGGGTCGCGATGCTGTC
GATGCACACGTCGCCCCTGGAGCAGCCCGGCACCGGCGACGCGGGCGGGATGAACGTCTACGTCATCGAGCTCGCCCGGC
AGCTGGCTGCGCTCGGCACCGAGGTGGAGGTCTTCACCCGGGCCGTGAGCAGCCGGCTCCCACCCGCCCTGGAGATCGCC
CCCGGGGTCATCGTCCGGCATGTGCCCGCCGGCCCGTTCGAGGACATCGGCCGCGAGGAGCTGCCCGCCTGGCTGTGCGC
CTTCACGGCGGACGTCCTGCGCACCGAGGCCGGCCACGCAGCGGGCTGGTTCGACGTCGTCCACTCGCACTACTGGCTGT
CCGGGCAGGTCGGGCTGTCGGCCGCCCGCCGGTGGGGCGTGCCTCTGGTGCACACGGCCCACACCCTGGCGCGGGTCAAG
AACGCCTCTCTCGCCGACGGCGACCGCCCCGAGCCGGAACCGCGCGTCCAGGGCGAGCAGGAGATCATCAAGGCGGCGAC
GCGGCTCATCGCGTCGACCGACACCGAGCGCCGCCACCTCACCCAGCTCTACGGCGCGGCGCCGGGCAAGGTGGACGTGG
TCGCCCCCGGCGTCGACCTTGACGTCTTCCGCCCCGGCGACCCCCGGGCCGCCCGCAAGCGGGTCGGCCTCGACCCCGAC
ACCCAGCTCCTCCTCTTCGTCGGACGCATCCAGCCGCTCAAGGCACCGGACGTCCTGCTCGCCGCCGCGGCCGAACTCAT
CCACCGCGACCCCGACCGCCGCGGACAGCTGGCGGTCGTCGTCGTCGGCGGCCCGAGCGGCTCCGGGCTCGAACGCCCGG
ACTCTCTGGTCAAGCTCGCCGCCGAACTCGGCATCACCGACATCGTCCGTTTCCAGCCGCCGGTACCCCAGGAGCAGCTC
GCCCACTGGTACCGCGCGGCGACAGCGGTCGTCGTCCCCAGCCACAGCGAGAGCTTCGGCCTGGTCGCGGTCGAGGCCCA
GGCCTGCGGCACCCCCGTGGTGGCCGCCTCCGTCGGCGGCCTGCGCACCGCCGTCGCCCACGGGACGTCCGGAGTCCTCG
TCCACGGCTGGGAGCCCGCCGACTACGCCGACGCCCTGGAACGCATCCTCACCGAGGAACGCTGGCGCCGGCACCTGTCG
ACAGGCGCCCGCCTGCGCGCCGCGAGCTTCGGCTGGACAGCGACCGCGAAAGGCGTCCTCGCGAGCTACCAGGCGGCGAT
CTCACCAGCGGCCGTCGCCGTCTGA

Upstream 100 bases:

>100_bases
GCTCGTACCGAGTGTGCCGGGCGGGCATAGGACGGCCACCGCCCGGTGTTGAACCGCTTTGGCGCCGGTCGTCGGGTAGA
TCTGCCTGTGGAGGTGGTTG

Downstream 100 bases:

>100_bases
CCCGCCCCGGCGAGCCGGTCACCGCCGACCCGCTCGGCGGACCAGCCACTCGGGCGTACCCTCCGTCGCCGAGTCGGCTA
GCGTCGCCGACGGCGGGTTC

Product: group 1 glycosyl transferase

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MHLVGGAPPEHPEPARPKPASRVAMLSMHTSPLEQPGTGDAGGMNVYVIELARQLAALGTEVEVFTRAVSSRLPPALEIA
PGVIVRHVPAGPFEDIGREELPAWLCAFTADVLRTEAGHAAGWFDVVHSHYWLSGQVGLSAARRWGVPLVHTAHTLARVK
NASLADGDRPEPEPRVQGEQEIIKAATRLIASTDTERRHLTQLYGAAPGKVDVVAPGVDLDVFRPGDPRAARKRVGLDPD
TQLLLFVGRIQPLKAPDVLLAAAAELIHRDPDRRGQLAVVVVGGPSGSGLERPDSLVKLAAELGITDIVRFQPPVPQEQL
AHWYRAATAVVVPSHSESFGLVAVEAQACGTPVVAASVGGLRTAVAHGTSGVLVHGWEPADYADALERILTEERWRRHLS
TGARLRAASFGWTATAKGVLASYQAAISPAAVAV

Sequences:

>Translated_434_residues
MHLVGGAPPEHPEPARPKPASRVAMLSMHTSPLEQPGTGDAGGMNVYVIELARQLAALGTEVEVFTRAVSSRLPPALEIA
PGVIVRHVPAGPFEDIGREELPAWLCAFTADVLRTEAGHAAGWFDVVHSHYWLSGQVGLSAARRWGVPLVHTAHTLARVK
NASLADGDRPEPEPRVQGEQEIIKAATRLIASTDTERRHLTQLYGAAPGKVDVVAPGVDLDVFRPGDPRAARKRVGLDPD
TQLLLFVGRIQPLKAPDVLLAAAAELIHRDPDRRGQLAVVVVGGPSGSGLERPDSLVKLAAELGITDIVRFQPPVPQEQL
AHWYRAATAVVVPSHSESFGLVAVEAQACGTPVVAASVGGLRTAVAHGTSGVLVHGWEPADYADALERILTEERWRRHLS
TGARLRAASFGWTATAKGVLASYQAAISPAAVAV
>Mature_434_residues
MHLVGGAPPEHPEPARPKPASRVAMLSMHTSPLEQPGTGDAGGMNVYVIELARQLAALGTEVEVFTRAVSSRLPPALEIA
PGVIVRHVPAGPFEDIGREELPAWLCAFTADVLRTEAGHAAGWFDVVHSHYWLSGQVGLSAARRWGVPLVHTAHTLARVK
NASLADGDRPEPEPRVQGEQEIIKAATRLIASTDTERRHLTQLYGAAPGKVDVVAPGVDLDVFRPGDPRAARKRVGLDPD
TQLLLFVGRIQPLKAPDVLLAAAAELIHRDPDRRGQLAVVVVGGPSGSGLERPDSLVKLAAELGITDIVRFQPPVPQEQL
AHWYRAATAVVVPSHSESFGLVAVEAQACGTPVVAASVGGLRTAVAHGTSGVLVHGWEPADYADALERILTEERWRRHLS
TGARLRAASFGWTATAKGVLASYQAAISPAAVAV

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSHA_FRASN (A8LDJ8)

Other databases:

- EMBL:   CP000820
- RefSeq:   YP_001510412.1
- ProteinModelPortal:   A8LDJ8
- GeneID:   5674483
- GenomeReviews:   CP000820_GR
- KEGG:   fre:Franean1_6162
- HOGENOM:   HBG726846
- OMA:   PLKAPDV
- ProtClustDB:   CLSK2298152
- BioCyc:   FSP1855:FRANEAN1_6162-MONOMER
- HAMAP:   MF_01695
- InterPro:   IPR001296
- InterPro:   IPR017814
- TIGRFAMs:   TIGR03449

Pfam domain/function: PF00534 Glycos_transf_1

EC number: =2.4.1.250

Molecular weight: Translated: 46021; Mature: 46021

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: BINDING 29-29 BINDING 43-43 BINDING 98-98 BINDING 131-131 BINDING 155-155 BINDING 175-175 BINDING 249-249 BINDING 254-254 BINDING 315-315 BINDING 337-337 BINDING 345-345

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLVGGAPPEHPEPARPKPASRVAMLSMHTSPLEQPGTGDAGGMNVYVIELARQLAALGT
CCCCCCCCCCCCCCCCCCCHHHEEEEEECCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCC
EVEVFTRAVSSRLPPALEIAPGVIVRHVPAGPFEDIGREELPAWLCAFTADVLRTEAGHA
HHHHHHHHHHHHCCCCHHHCCCEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCC
AGWFDVVHSHYWLSGQVGLSAARRWGVPLVHTAHTLARVKNASLADGDRPEPEPRVQGEQ
HHHHHHHHHHEEECCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
EIIKAATRLIASTDTERRHLTQLYGAAPGKVDVVAPGVDLDVFRPGDPRAARKRVGLDPD
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCCCHHHHHHCCCCCC
TQLLLFVGRIQPLKAPDVLLAAAAELIHRDPDRRGQLAVVVVGGPSGSGLERPDSLVKLA
CEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHH
AELGITDIVRFQPPVPQEQLAHWYRAATAVVVPSHSESFGLVAVEAQACGTPVVAASVGG
HHCCHHHHHCCCCCCCHHHHHHHHHHHEEEEECCCCCCCCEEEEEHHHCCCCEEEHHHCH
LRTAVAHGTSGVLVHGWEPADYADALERILTEERWRRHLSTGARLRAASFGWTATAKGVL
HHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHH
ASYQAAISPAAVAV
HHHHHHCCCHHHCC
>Mature Secondary Structure
MHLVGGAPPEHPEPARPKPASRVAMLSMHTSPLEQPGTGDAGGMNVYVIELARQLAALGT
CCCCCCCCCCCCCCCCCCCHHHEEEEEECCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCC
EVEVFTRAVSSRLPPALEIAPGVIVRHVPAGPFEDIGREELPAWLCAFTADVLRTEAGHA
HHHHHHHHHHHHCCCCHHHCCCEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCC
AGWFDVVHSHYWLSGQVGLSAARRWGVPLVHTAHTLARVKNASLADGDRPEPEPRVQGEQ
HHHHHHHHHHEEECCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHH
EIIKAATRLIASTDTERRHLTQLYGAAPGKVDVVAPGVDLDVFRPGDPRAARKRVGLDPD
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCCCHHHHHHCCCCCC
TQLLLFVGRIQPLKAPDVLLAAAAELIHRDPDRRGQLAVVVVGGPSGSGLERPDSLVKLA
CEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHH
AELGITDIVRFQPPVPQEQLAHWYRAATAVVVPSHSESFGLVAVEAQACGTPVVAASVGG
HHCCHHHHHCCCCCCCHHHHHHHHHHHEEEEECCCCCCCCEEEEEHHHCCCCEEEHHHCH
LRTAVAHGTSGVLVHGWEPADYADALERILTEERWRRHLSTGARLRAASFGWTATAKGVL
HHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHH
ASYQAAISPAAVAV
HHHHHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA