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The map label for this gene is glmS [H]

Identifier: 158317757

GI number: 158317757

Start: 7335733

End: 7337628

Strand: Reverse

Name: glmS [H]

Synonym: Franean1_6015

Alternate gene names: 158317757

Gene position: 7337628-7335733 (Counterclockwise)

Preceding gene: 158317758

Following gene: 158317755

Centisome position: 81.69

GC content: 71.73

Gene sequence:

>1896_bases
ATGTGCGGGATCATTGGTTACGTCGGTGATCAATCAGCCTTGGACGTCGCGCTGAGCGGGCTGCGCCGGCTGGAGTACCG
CGGCTACGACTCCGCGGGTGTCGCCGTCGTCGGCGCGGGTGCGCTGAGAACCGCGCGCCGCGCCGGGCGGCTGGCGAACC
TGGAGAAGATCCTCGGCGAGGACAACGACCCCATGCCCGGCACGACCGGGATGGGGCACACTCGCTGGGCGACGCACGGC
GGCCCGACCGACGTCAACGCCCACCCGCACACCGACTGCACCGGCACCGTCGCGGTGATCCACAACGGCATCATCGAGAA
CTTCGCGGAGCTGCGCGCCGAGCTGGAGGCCGCCGGCCACGAGCTGGCCAGCGAGACCGACACCGAGGTCGTCGCCCACC
TGCTCGAGATCGAGATGGCCCGTGATCCCGGCTCCCGCCCGGCGGGGGGTGCGGCGGGGTCGGCGCTCCCGCACCCGCTC
AGCGAGGCTTTGCGCATCGTGTGCCGCCGGCTGGAGGGCGCGTTCACGCTCGTCGTCCTGCACCGCGACCATCCCGAGGT
CGTCGTGGGCGCGCGGCGCAACAGTCCGCTCGTCGTCGGCCTCGGCGCGGGCGAGACCTTCCTGGCCAGCGACGTCTCCG
CGTTCATCGCGCACACCCGTGAGGCGCTCGAGATCGGCCAGGACCAGCTCGTCGAGGCCCGGCGCGACGGTGTGACCGTC
TACGACTTCGCCGGCGCCGTCGTCGAGGGGCGCCGCTACCACGTCGACTGGGACGCGAGCGCCGCCGAGAAGGGCGGCTA
CCCCTACTTCATGCTGAAGGAGATCAGCGAGCAGCCCACGGCGCTCGCCGACACGCTGCGCGGGCGGCTCTCCGCGGAGG
GCACCATCGTCCTGGACGAGGAGCGCCTCTCCGACCAGGACTTCCGCGACATCGACAAGGTCTTCATCGTGGCCTGCGGG
ACGGCCTACCATGCCGGCCTGATCGCCAAGTACGCGATCGAGCACTGGACGCGGCTGCCCTGCGAGGTCGAGATGGCCTC
GGAGTTCCGCTACCGCGACCCGGTGCTGGACCGCTCGACGCTGGTCGTCGCGATCAGCCAGAGCGGCGAGACGCTCGACA
CCCTGATGGCGGTCAAGCACGCCCGTGAGCAGAAGGCCCGCGTGCTGGCGATCTGCAACACGAACGGCTCGACGATCCCG
CGCGAGTCGGACGCCGTTCTGTACACCCGGTGTGGTCCCGAGGTGGGCGTGGCGGCGACGAAGACGTTCCTCGGGCAGGT
GGCGGCCTGCCTGCTCGTCGGCCTGTTCCTGGCGCAGACCCGGGGCGTCCTCTACGGCGACGAGGTCGCCGCCTACGTGG
ACCGGCTACAGCGCGTCCCGGAGCTCGTCCGGCGCACGCTCGCCACCGTCGAGCCGGTGCGGGAGCTCGCCCGCAGCCTG
GCCGACGCCAAGGCGGTGCTGTTCCTCGGCCGCCACGTCGGCTACCCGGTGGCACTGGAGGGCGCGCTGAAGCTGAAGGA
ACTGGCCTACATGCACGCCGAGGGCTTCCCGGCCGGGGAGCTGAAGCACGGCCCGATCGCGCTGATCGAGCCCGGCCTGC
CGGTGGTCGTGGTCGTGCCGTCGCCGCGCGGGCGGGCGAGCCTGCACGGGAAGATCGTCTCCAACATCCAGGAGGTCCGT
GCCCGCGGCGCACGCACGATCGTGATCGCGGAGGAGGGCGACACCGCCGTCGAGCCCTACGCGGACCACCTGATCCGGGT
TCCCGCCACGTCATCGCTGTTCGCGCCGCTGGTCACGACCCTGCCGCTGCAGGTCTTCGCCTGCGAGCTCGCGCTCGCGC
GCGGGCTGGACGTCGACCAGCCGCGCAACCTGGCCAAGTCCGTCACGGTCGAGTAG

Upstream 100 bases:

>100_bases
CGGGCACGTGCCGGTGGATTCGGCCGACGCCGACGGGACATCTCCGGCAACCGAGTGGTCCGTGCCTGGCGCTCGGACCG
GACTGCGTACGCTGAGCAAC

Downstream 100 bases:

>100_bases
CACCAGCGCGGCCTGGGCCGAGGGTCGTCAGGTGCGTCGCCTCGGCACCGCGGCGGAGGGGCGCGCCGGTGTGGTGGCCG
GCACGCCCCCGTCTGGCGTC

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MCGIIGYVGDQSALDVALSGLRRLEYRGYDSAGVAVVGAGALRTARRAGRLANLEKILGEDNDPMPGTTGMGHTRWATHG
GPTDVNAHPHTDCTGTVAVIHNGIIENFAELRAELEAAGHELASETDTEVVAHLLEIEMARDPGSRPAGGAAGSALPHPL
SEALRIVCRRLEGAFTLVVLHRDHPEVVVGARRNSPLVVGLGAGETFLASDVSAFIAHTREALEIGQDQLVEARRDGVTV
YDFAGAVVEGRRYHVDWDASAAEKGGYPYFMLKEISEQPTALADTLRGRLSAEGTIVLDEERLSDQDFRDIDKVFIVACG
TAYHAGLIAKYAIEHWTRLPCEVEMASEFRYRDPVLDRSTLVVAISQSGETLDTLMAVKHAREQKARVLAICNTNGSTIP
RESDAVLYTRCGPEVGVAATKTFLGQVAACLLVGLFLAQTRGVLYGDEVAAYVDRLQRVPELVRRTLATVEPVRELARSL
ADAKAVLFLGRHVGYPVALEGALKLKELAYMHAEGFPAGELKHGPIALIEPGLPVVVVVPSPRGRASLHGKIVSNIQEVR
ARGARTIVIAEEGDTAVEPYADHLIRVPATSSLFAPLVTTLPLQVFACELALARGLDVDQPRNLAKSVTVE

Sequences:

>Translated_631_residues
MCGIIGYVGDQSALDVALSGLRRLEYRGYDSAGVAVVGAGALRTARRAGRLANLEKILGEDNDPMPGTTGMGHTRWATHG
GPTDVNAHPHTDCTGTVAVIHNGIIENFAELRAELEAAGHELASETDTEVVAHLLEIEMARDPGSRPAGGAAGSALPHPL
SEALRIVCRRLEGAFTLVVLHRDHPEVVVGARRNSPLVVGLGAGETFLASDVSAFIAHTREALEIGQDQLVEARRDGVTV
YDFAGAVVEGRRYHVDWDASAAEKGGYPYFMLKEISEQPTALADTLRGRLSAEGTIVLDEERLSDQDFRDIDKVFIVACG
TAYHAGLIAKYAIEHWTRLPCEVEMASEFRYRDPVLDRSTLVVAISQSGETLDTLMAVKHAREQKARVLAICNTNGSTIP
RESDAVLYTRCGPEVGVAATKTFLGQVAACLLVGLFLAQTRGVLYGDEVAAYVDRLQRVPELVRRTLATVEPVRELARSL
ADAKAVLFLGRHVGYPVALEGALKLKELAYMHAEGFPAGELKHGPIALIEPGLPVVVVVPSPRGRASLHGKIVSNIQEVR
ARGARTIVIAEEGDTAVEPYADHLIRVPATSSLFAPLVTTLPLQVFACELALARGLDVDQPRNLAKSVTVE
>Mature_631_residues
MCGIIGYVGDQSALDVALSGLRRLEYRGYDSAGVAVVGAGALRTARRAGRLANLEKILGEDNDPMPGTTGMGHTRWATHG
GPTDVNAHPHTDCTGTVAVIHNGIIENFAELRAELEAAGHELASETDTEVVAHLLEIEMARDPGSRPAGGAAGSALPHPL
SEALRIVCRRLEGAFTLVVLHRDHPEVVVGARRNSPLVVGLGAGETFLASDVSAFIAHTREALEIGQDQLVEARRDGVTV
YDFAGAVVEGRRYHVDWDASAAEKGGYPYFMLKEISEQPTALADTLRGRLSAEGTIVLDEERLSDQDFRDIDKVFIVACG
TAYHAGLIAKYAIEHWTRLPCEVEMASEFRYRDPVLDRSTLVVAISQSGETLDTLMAVKHAREQKARVLAICNTNGSTIP
RESDAVLYTRCGPEVGVAATKTFLGQVAACLLVGLFLAQTRGVLYGDEVAAYVDRLQRVPELVRRTLATVEPVRELARSL
ADAKAVLFLGRHVGYPVALEGALKLKELAYMHAEGFPAGELKHGPIALIEPGLPVVVVVPSPRGRASLHGKIVSNIQEVR
ARGARTIVIAEEGDTAVEPYADHLIRVPATSSLFAPLVTTLPLQVFACELALARGLDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=698, Percent_Identity=33.6676217765043, Blast_Score=384, Evalue=1e-106,
Organism=Homo sapiens, GI205277386, Length=701, Percent_Identity=34.0941512125535, Blast_Score=382, Evalue=1e-106,
Organism=Homo sapiens, GI29570798, Length=209, Percent_Identity=27.7511961722488, Blast_Score=70, Evalue=7e-12,
Organism=Escherichia coli, GI1790167, Length=634, Percent_Identity=43.3753943217666, Blast_Score=490, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI17532899, Length=435, Percent_Identity=35.8620689655172, Blast_Score=278, Evalue=9e-75,
Organism=Caenorhabditis elegans, GI17532897, Length=435, Percent_Identity=35.8620689655172, Blast_Score=277, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17539970, Length=436, Percent_Identity=35.7798165137615, Blast_Score=270, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6322745, Length=443, Percent_Identity=34.9887133182844, Blast_Score=250, Evalue=6e-67,
Organism=Saccharomyces cerevisiae, GI6323731, Length=392, Percent_Identity=27.8061224489796, Blast_Score=160, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6323730, Length=220, Percent_Identity=33.6363636363636, Blast_Score=117, Evalue=6e-27,
Organism=Drosophila melanogaster, GI21357745, Length=701, Percent_Identity=34.0941512125535, Blast_Score=402, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 67719; Mature: 67719

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIIGYVGDQSALDVALSGLRRLEYRGYDSAGVAVVGAGALRTARRAGRLANLEKILGE
CCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCC
DNDPMPGTTGMGHTRWATHGGPTDVNAHPHTDCTGTVAVIHNGIIENFAELRAELEAAGH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ELASETDTEVVAHLLEIEMARDPGSRPAGGAAGSALPHPLSEALRIVCRRLEGAFTLVVL
HHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEE
HRDHPEVVVGARRNSPLVVGLGAGETFLASDVSAFIAHTREALEIGQDQLVEARRDGVTV
ECCCCCEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEE
YDFAGAVVEGRRYHVDWDASAAEKGGYPYFMLKEISEQPTALADTLRGRLSAEGTIVLDE
EECCCHHCCCCEEEECCCCCHHHCCCCCEEEHHHHCCCCHHHHHHHHHCCCCCCEEEEEH
ERLSDQDFRDIDKVFIVACGTAYHAGLIAKYAIEHWTRLPCEVEMASEFRYRDPVLDRST
HHCCCCCHHHHHHEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCCCCCCE
LVVAISQSGETLDTLMAVKHAREQKARVLAICNTNGSTIPRESDAVLYTRCGPEVGVAAT
EEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCHHHH
KTFLGQVAACLLVGLFLAQTRGVLYGDEVAAYVDRLQRVPELVRRTLATVEPVRELARSL
HHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADAKAVLFLGRHVGYPVALEGALKLKELAYMHAEGFPAGELKHGPIALIEPGLPVVVVVP
HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCEEEEEC
SPRGRASLHGKIVSNIQEVRARGARTIVIAEEGDTAVEPYADHLIRVPATSSLFAPLVTT
CCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHCEEECCCCHHHHHHHHHH
LPLQVFACELALARGLDVDQPRNLAKSVTVE
HHHHHHHHHHHHHHCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MCGIIGYVGDQSALDVALSGLRRLEYRGYDSAGVAVVGAGALRTARRAGRLANLEKILGE
CCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCC
DNDPMPGTTGMGHTRWATHGGPTDVNAHPHTDCTGTVAVIHNGIIENFAELRAELEAAGH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ELASETDTEVVAHLLEIEMARDPGSRPAGGAAGSALPHPLSEALRIVCRRLEGAFTLVVL
HHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEE
HRDHPEVVVGARRNSPLVVGLGAGETFLASDVSAFIAHTREALEIGQDQLVEARRDGVTV
ECCCCCEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEE
YDFAGAVVEGRRYHVDWDASAAEKGGYPYFMLKEISEQPTALADTLRGRLSAEGTIVLDE
EECCCHHCCCCEEEECCCCCHHHCCCCCEEEHHHHCCCCHHHHHHHHHCCCCCCEEEEEH
ERLSDQDFRDIDKVFIVACGTAYHAGLIAKYAIEHWTRLPCEVEMASEFRYRDPVLDRST
HHCCCCCHHHHHHEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCCCCCCE
LVVAISQSGETLDTLMAVKHAREQKARVLAICNTNGSTIPRESDAVLYTRCGPEVGVAAT
EEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCHHHH
KTFLGQVAACLLVGLFLAQTRGVLYGDEVAAYVDRLQRVPELVRRTLATVEPVRELARSL
HHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADAKAVLFLGRHVGYPVALEGALKLKELAYMHAEGFPAGELKHGPIALIEPGLPVVVVVP
HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCEEEEEC
SPRGRASLHGKIVSNIQEVRARGARTIVIAEEGDTAVEPYADHLIRVPATSSLFAPLVTT
CCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHCEEECCCCHHHHHHHHHH
LPLQVFACELALARGLDVDQPRNLAKSVTVE
HHHHHHHHHHHHHHCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]