Click here to switch to the map view.

The map label for this gene is tdcB [H]

Identifier: 158317730

GI number: 158317730

Start: 7297868

End: 7299310

Strand: Reverse

Name: tdcB [H]

Synonym: Franean1_5988

Alternate gene names: 158317730

Gene position: 7299310-7297868 (Counterclockwise)

Preceding gene: 158317731

Following gene: 158317729

Centisome position: 81.27

GC content: 75.95

Gene sequence:

>1443_bases
ATGACATCACCATCCGTGAGCGGGCCCTCGGCTACCGGCGCCTCGCCGTCCCGGGTGGGCGACACGGCTGACGCTGACGA
CACGGGAGATCGCGAGGCCGTGGCAGCCCCGACCGTAACTCCGGTCACCCCGGCCGTCGCCCGGGTCGGAGCGCGGCCGG
GGCTGCTGCGGCCAGGCAACGCGCGCAGGGCGTCCACGCGACGCACGTTCGGCCCCCGAGCGGCCGCGTCCGGCCGGGAA
GCAGGATGCCGCCCAGGCAACGGCACTCCGCTGCCGCCCGATGCCACGGTGCCGGCAGGAACGCTGGCTGCTGAGGCGCT
GGCTGCTGAGACGCTGTCGGTCGGCGCGCTGGCGGTCGACGTCGCCGACGTGGTGGCCGCCGCCGACGGGCTGCGGGGGG
TCGCCCGGCGCACCCGGGTCGCGGCCGACGCCGACCTGACCCGGCTCACCGGCTCGCCGGTCTGGCTCAAGTGCGAGCAC
GAGCAACACACCGGTTCGTTCAAGCTGCGCGGCGCATATCACCGGATCGCGGCCGCTGGCCCGCGCGCCCGCGAGCGGGG
GGTCGTGGCCGCGAGCGCGGGTAACCACGCGCAGGGCGTCGCCTTCGCCGCGGCCCGGTTCGGCGTCGAAGCGACGATCT
TCGTGCCGGAGAGCGCCAACCCGTCGAAGGTCGCCAGCACCCGGCGTTGGGGCGCCCGGGTCGAGTACGTCCCGGGCGGG
GTCGACGCGGCGCTCGCGGCGGCGGCCGCGTTCGCGAACGAGGGCGGCCGGCTGCTGGTCCATCCCTTCGACGACGCCGC
CGTCATCGCCGGGCAGGGGACGATCGGGCTGGAACTGCTCGAGCAGGTCCCGAACCTCGCCACCGTCATCGTCGGAGTCG
GCGGCGGTGGTCTCCTGTGTGGCCTTGCCGTAGCGATCAAGGGCCTGCGCCCGGACGTCCGCGTCATCGGCGTCCAGTCC
GCCGCCGCGCCGGCCTTCGCCACATCCTTCCGCACCGGTCGCCGCGTCACGGTGCCCCCGGGCAGCGCCGGCACGACGGG
GACGGTCGGCCAGCCGGGAACCGCCGCCGGCACCATCGCTGACGGGATGGCCGTGGCCGCGCCCGGGCGGCTCACCCTCG
AGCTCGCCACCCGTCTCGTCGACGACGTCGTCACGGTCGACGAGAGTGCGTTCTGGGAGGCGATGGTCCTGCTGCGCCGG
ACGGGTCAGCGGGTGGAGCCCGCGGGCGCGGCGGGTGTCGCCGCGTTGCTGCGGACCCCCCGGCTCGCGGTCGGGCCCAC
CGCGGTGGTGATCTCTGGCGGCAACCTCGACCCGGCCGTCGACGCCAGGGTCGCCGCACTCGCCGACGCTGGTGCTGGTG
CTGGTGCTCTCAGCGCTGCCGGTACCGGCACCGTCGGTGCCGACCCGGCCGGCTCGGCCGCGGGCCGTCGAACGGTTGCC
TGA

Upstream 100 bases:

>100_bases
GAACGGGTCGCGCGCCCAGCCCTTCCGCCCTACGGCGGGGGGCTTTTTTGTTTGCCGCGGCCACAGCGAGGTGGCCGCCG
AGCCACCCAGGAGATCTTCG

Downstream 100 bases:

>100_bases
CCGCCCGCTGCGCCGACCGGCGGGCCTGTGCCCGGAGGTTGGGGCAGGCACGACCCGGCCGCGAGGGCTCGGGCGGGGCA
TGGAAGTGTCGGACCCGCCC

Product: pyridoxal-5'-phosphate-dependent protein subunit beta

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MTSPSVSGPSATGASPSRVGDTADADDTGDREAVAAPTVTPVTPAVARVGARPGLLRPGNARRASTRRTFGPRAAASGRE
AGCRPGNGTPLPPDATVPAGTLAAEALAAETLSVGALAVDVADVVAAADGLRGVARRTRVAADADLTRLTGSPVWLKCEH
EQHTGSFKLRGAYHRIAAAGPRARERGVVAASAGNHAQGVAFAAARFGVEATIFVPESANPSKVASTRRWGARVEYVPGG
VDAALAAAAAFANEGGRLLVHPFDDAAVIAGQGTIGLELLEQVPNLATVIVGVGGGGLLCGLAVAIKGLRPDVRVIGVQS
AAAPAFATSFRTGRRVTVPPGSAGTTGTVGQPGTAAGTIADGMAVAAPGRLTLELATRLVDDVVTVDESAFWEAMVLLRR
TGQRVEPAGAAGVAALLRTPRLAVGPTAVVISGGNLDPAVDARVAALADAGAGAGALSAAGTGTVGADPAGSAAGRRTVA

Sequences:

>Translated_480_residues
MTSPSVSGPSATGASPSRVGDTADADDTGDREAVAAPTVTPVTPAVARVGARPGLLRPGNARRASTRRTFGPRAAASGRE
AGCRPGNGTPLPPDATVPAGTLAAEALAAETLSVGALAVDVADVVAAADGLRGVARRTRVAADADLTRLTGSPVWLKCEH
EQHTGSFKLRGAYHRIAAAGPRARERGVVAASAGNHAQGVAFAAARFGVEATIFVPESANPSKVASTRRWGARVEYVPGG
VDAALAAAAAFANEGGRLLVHPFDDAAVIAGQGTIGLELLEQVPNLATVIVGVGGGGLLCGLAVAIKGLRPDVRVIGVQS
AAAPAFATSFRTGRRVTVPPGSAGTTGTVGQPGTAAGTIADGMAVAAPGRLTLELATRLVDDVVTVDESAFWEAMVLLRR
TGQRVEPAGAAGVAALLRTPRLAVGPTAVVISGGNLDPAVDARVAALADAGAGAGALSAAGTGTVGADPAGSAAGRRTVA
>Mature_479_residues
TSPSVSGPSATGASPSRVGDTADADDTGDREAVAAPTVTPVTPAVARVGARPGLLRPGNARRASTRRTFGPRAAASGREA
GCRPGNGTPLPPDATVPAGTLAAEALAAETLSVGALAVDVADVVAAADGLRGVARRTRVAADADLTRLTGSPVWLKCEHE
QHTGSFKLRGAYHRIAAAGPRARERGVVAASAGNHAQGVAFAAARFGVEATIFVPESANPSKVASTRRWGARVEYVPGGV
DAALAAAAAFANEGGRLLVHPFDDAAVIAGQGTIGLELLEQVPNLATVIVGVGGGGLLCGLAVAIKGLRPDVRVIGVQSA
AAPAFATSFRTGRRVTVPPGSAGTTGTVGQPGTAAGTIADGMAVAAPGRLTLELATRLVDDVVTVDESAFWEAMVLLRRT
GQRVEPAGAAGVAALLRTPRLAVGPTAVVISGGNLDPAVDARVAALADAGAGAGALSAAGTGTVGADPAGSAAGRRTVA

Specific function: Acts on both serine and threonine, and properly considered as a hydroxy amino acid deaminase [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=336, Percent_Identity=35.4166666666667, Blast_Score=169, Evalue=4e-42,
Organism=Escherichia coli, GI1789505, Length=338, Percent_Identity=36.094674556213, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1790207, Length=293, Percent_Identity=37.8839590443686, Blast_Score=136, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71991565, Length=328, Percent_Identity=33.8414634146341, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17508781, Length=291, Percent_Identity=31.9587628865979, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17537387, Length=318, Percent_Identity=30.5031446540881, Blast_Score=96, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6322631, Length=317, Percent_Identity=34.384858044164, Blast_Score=140, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6320930, Length=300, Percent_Identity=35.6666666666667, Blast_Score=139, Evalue=9e-34,
Organism=Drosophila melanogaster, GI21355833, Length=330, Percent_Identity=32.1212121212121, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24645328, Length=234, Percent_Identity=32.4786324786325, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005789 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 47317; Mature: 47186

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPSVSGPSATGASPSRVGDTADADDTGDREAVAAPTVTPVTPAVARVGARPGLLRPGN
CCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHCCCCCCCCCCC
ARRASTRRTFGPRAAASGREAGCRPGNGTPLPPDATVPAGTLAAEALAAETLSVGALAVD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VADVVAAADGLRGVARRTRVAADADLTRLTGSPVWLKCEHEQHTGSFKLRGAYHRIAAAG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEECCCCCCCCEEECCHHHHHHHCC
PRARERGVVAASAGNHAQGVAFAAARFGVEATIFVPESANPSKVASTRRWGARVEYVPGG
CCHHHCCEEEECCCCCCCHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCEEEECCCC
VDAALAAAAAFANEGGRLLVHPFDDAAVIAGQGTIGLELLEQVPNLATVIVGVGGGGLLC
HHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCHHHHHHHHCCCEEEEEEECCCCHHHH
GLAVAIKGLRPDVRVIGVQSAAAPAFATSFRTGRRVTVPPGSAGTTGTVGQPGTAAGTIA
HHHHHHHCCCCCEEEEEECCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCHHH
DGMAVAAPGRLTLELATRLVDDVVTVDESAFWEAMVLLRRTGQRVEPAGAAGVAALLRTP
CCEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
RLAVGPTAVVISGGNLDPAVDARVAALADAGAGAGALSAAGTGTVGADPAGSAAGRRTVA
CEEECCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TSPSVSGPSATGASPSRVGDTADADDTGDREAVAAPTVTPVTPAVARVGARPGLLRPGN
CCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHCCCCCCCCCCC
ARRASTRRTFGPRAAASGREAGCRPGNGTPLPPDATVPAGTLAAEALAAETLSVGALAVD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VADVVAAADGLRGVARRTRVAADADLTRLTGSPVWLKCEHEQHTGSFKLRGAYHRIAAAG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEECCCCCCCCEEECCHHHHHHHCC
PRARERGVVAASAGNHAQGVAFAAARFGVEATIFVPESANPSKVASTRRWGARVEYVPGG
CCHHHCCEEEECCCCCCCHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCEEEECCCC
VDAALAAAAAFANEGGRLLVHPFDDAAVIAGQGTIGLELLEQVPNLATVIVGVGGGGLLC
HHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCHHHHHHHHCCCEEEEEEECCCCHHHH
GLAVAIKGLRPDVRVIGVQSAAAPAFATSFRTGRRVTVPPGSAGTTGTVGQPGTAAGTIA
HHHHHHHCCCCCEEEEEECCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCHHH
DGMAVAAPGRLTLELATRLVDDVVTVDESAFWEAMVLLRRTGQRVEPAGAAGVAALLRTP
CCEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
RLAVGPTAVVISGGNLDPAVDARVAALADAGAGAGALSAAGTGTVGADPAGSAAGRRTVA
CEEECCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA