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The map label for this gene is accD [H]

Identifier: 158317724

GI number: 158317724

Start: 7290091

End: 7291671

Strand: Direct

Name: accD [H]

Synonym: Franean1_5982

Alternate gene names: 158317724

Gene position: 7290091-7291671 (Clockwise)

Preceding gene: 158317715

Following gene: 158317725

Centisome position: 81.16

GC content: 77.74

Gene sequence:

>1581_bases
ATGGCTGAGCGCGATTCCACCGCCACGGCCCAGGACTGGCGGGCCGCCGTCCTGGCCGATGTCATCCGCCGGCCCGCCGT
CGCCGGCGCACCCAACCGCCTCGGCTGGCCGGGCTACGACGGACGTCCCGCGCTGTGGTGGGGCACCGGCCCGGTCGAGG
GCGTGGACGCCGTCGTCGCGGTCTGGGACTTCGCGGTCAACGGGGGCAGCTTCGGGGAGGCCGACGCGGGCGCGTTCGCG
GACGCGGCGGCCGAGGCCGTCGCCGGGCGGCGTCCGCTGGTGTCACTCGTGCGCAGCGGCGGGACGCGGCTGCAGGAGGG
CGTGGCCGGGCTGGTGGGGCTGGCCCGGGTGTCCCTCGCGCTCGCCGAGGTCGCCGCGGCGGGCCTCCCCCATGTCGCCG
TCTCGGACCAGCCGACCACCGGCGGGATGTGGGTCACCGTGGGCTCCCGCGCCGATCTGCGGTGCGCCGTGCTGGGCGCG
ACGGTGGGGTTCGCCGGGCCCCGGGTGGTGGCCGCGGTCACCGGCGAGGCTCCCCCGGCCGGCGCCAGCCACACGGCGGC
GGCCGCCCACGCCGCCGGGCTGGTGGACGCGGCCGTCGCGCCAGCCGCCGTCGCCTCGTGGCTGCGGCGCGCGCTGGACG
CGGTCGCCGTTCCCGCCCGTGTCCTACCCGCCGCGCGCACACCCGACCGGCCTGTCAGGACAGACGCCGACGGCGACCGG
GCCGGCATCGCCGACAACAGCCGGGCCGACGCCAGCCAGGCGGGGAGTGGGCCGGCGCCGGCCCGCGGCGGATGGGAGCA
GGTCCTCGCCGCCCGCACCGGCCAGCGCAGGCATGCGGGCGACATCCTGGACGGCCTGTTCCCCGCCGGGGTGGACCTGA
CCGGCCCGGACCGCACGGTGCGCGCCCGGGTCGGCCGGCTGGCCGGGACGCCCGTCGCCGACGGGGAACACAGCGCCGAC
GGGGAATTGAGCGCAGGCGGTGAACCCGGCGCAGGCGGGCTCGGGCCGCGCGCCGTGGGGGTCGCGCTGGCGGCCGAACG
CGGCGGTGCGCCGGGGCCGGCCGGGTACCGGCTGCTCGTGCGGGCCGCGGGCCTCGCCAGCCGGCTCGGCCTGCCACTCG
TCACGCTGGTCGACACCCCGGGGGCGGAGTGCGGGCCAGCGGCCGAGGCGGGTGGCATCGCGGCCGAGATCGGCACGGCG
ATGGCGGAGGTGCTCGGCTGCGCGTCGCCGACGCTCTCCGTGATCGTCGGTGAGGGCGGCTCGGGTGGGGCGCTGGCGGC
GTGCTGTACCGATGTGGTCCTGATGTCGCCGGACAGCTACGTCACGGCGCTGTCCCCCGAGGGCACGGCCACCACGCTCC
GGATCAGCGTCGAGCAGGCCGCGGACACCGCGGGGCTGCGCCCGTCGGACCTGGTCAGCCTGGGTTTCGCCGACGGCGTC
CTCGCGCCGCGCGACACTGGTCCGCCCGGCCTGGCACACCGGGTGACCGAGGTGCTGACCGAGCTGACGATGCGCGACAG
TGATGTCCGCCTTCGCCAACGAAGGGCAAAATGGTCGACAGGATTGGGTGGCTTTCTGTAA

Upstream 100 bases:

>100_bases
GGCCGGCCGTGGCGGGCCGACGGTGACCGGGGGGCGGGCGGACGAGCGATCCCACACGTCACAGCACTGCCGGAGCCGAT
CGCGGCGAGGATCTGTAGGC

Downstream 100 bases:

>100_bases
CGTCGTTGACCCAACCTGCCACGGGAGACAGGTCGTCACGAAGGGGACGGTCATCGACACTCGGCTGTTCACCTGGATCG
GCGGCGCCCAGCTCGACGGC

Product: carboxyl transferase

Products: NA

Alternate protein names: ACCase subunits beta/alpha; Acetyl-CoA carboxylase carboxyltransferase subunits beta/alpha [H]

Number of amino acids: Translated: 526; Mature: 525

Protein sequence:

>526_residues
MAERDSTATAQDWRAAVLADVIRRPAVAGAPNRLGWPGYDGRPALWWGTGPVEGVDAVVAVWDFAVNGGSFGEADAGAFA
DAAAEAVAGRRPLVSLVRSGGTRLQEGVAGLVGLARVSLALAEVAAAGLPHVAVSDQPTTGGMWVTVGSRADLRCAVLGA
TVGFAGPRVVAAVTGEAPPAGASHTAAAAHAAGLVDAAVAPAAVASWLRRALDAVAVPARVLPAARTPDRPVRTDADGDR
AGIADNSRADASQAGSGPAPARGGWEQVLAARTGQRRHAGDILDGLFPAGVDLTGPDRTVRARVGRLAGTPVADGEHSAD
GELSAGGEPGAGGLGPRAVGVALAAERGGAPGPAGYRLLVRAAGLASRLGLPLVTLVDTPGAECGPAAEAGGIAAEIGTA
MAEVLGCASPTLSVIVGEGGSGGALAACCTDVVLMSPDSYVTALSPEGTATTLRISVEQAADTAGLRPSDLVSLGFADGV
LAPRDTGPPGLAHRVTEVLTELTMRDSDVRLRQRRAKWSTGLGGFL

Sequences:

>Translated_526_residues
MAERDSTATAQDWRAAVLADVIRRPAVAGAPNRLGWPGYDGRPALWWGTGPVEGVDAVVAVWDFAVNGGSFGEADAGAFA
DAAAEAVAGRRPLVSLVRSGGTRLQEGVAGLVGLARVSLALAEVAAAGLPHVAVSDQPTTGGMWVTVGSRADLRCAVLGA
TVGFAGPRVVAAVTGEAPPAGASHTAAAAHAAGLVDAAVAPAAVASWLRRALDAVAVPARVLPAARTPDRPVRTDADGDR
AGIADNSRADASQAGSGPAPARGGWEQVLAARTGQRRHAGDILDGLFPAGVDLTGPDRTVRARVGRLAGTPVADGEHSAD
GELSAGGEPGAGGLGPRAVGVALAAERGGAPGPAGYRLLVRAAGLASRLGLPLVTLVDTPGAECGPAAEAGGIAAEIGTA
MAEVLGCASPTLSVIVGEGGSGGALAACCTDVVLMSPDSYVTALSPEGTATTLRISVEQAADTAGLRPSDLVSLGFADGV
LAPRDTGPPGLAHRVTEVLTELTMRDSDVRLRQRRAKWSTGLGGFL
>Mature_525_residues
AERDSTATAQDWRAAVLADVIRRPAVAGAPNRLGWPGYDGRPALWWGTGPVEGVDAVVAVWDFAVNGGSFGEADAGAFAD
AAAEAVAGRRPLVSLVRSGGTRLQEGVAGLVGLARVSLALAEVAAAGLPHVAVSDQPTTGGMWVTVGSRADLRCAVLGAT
VGFAGPRVVAAVTGEAPPAGASHTAAAAHAAGLVDAAVAPAAVASWLRRALDAVAVPARVLPAARTPDRPVRTDADGDRA
GIADNSRADASQAGSGPAPARGGWEQVLAARTGQRRHAGDILDGLFPAGVDLTGPDRTVRARVGRLAGTPVADGEHSADG
ELSAGGEPGAGGLGPRAVGVALAAERGGAPGPAGYRLLVRAAGLASRLGLPLVTLVDTPGAECGPAAEAGGIAAEIGTAM
AEVLGCASPTLSVIVGEGGSGGALAACCTDVVLMSPDSYVTALSPEGTATTLRISVEQAADTAGLRPSDLVSLGFADGVL
APRDTGPPGLAHRVTEVLTELTMRDSDVRLRQRRAKWSTGLGGFL

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the AccA family [H]

Homologues:

Organism=Escherichia coli, GI1788655, Length=144, Percent_Identity=35.4166666666667, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1786382, Length=245, Percent_Identity=30.2040816326531, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001095
- InterPro:   IPR000438
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF03255 ACCA [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 52202; Mature: 52071

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERDSTATAQDWRAAVLADVIRRPAVAGAPNRLGWPGYDGRPALWWGTGPVEGVDAVVA
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHH
VWDFAVNGGSFGEADAGAFADAAAEAVAGRRPLVSLVRSGGTRLQEGVAGLVGLARVSLA
HHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LAEVAAAGLPHVAVSDQPTTGGMWVTVGSRADLRCAVLGATVGFAGPRVVAAVTGEAPPA
HHHHHHCCCCCEEECCCCCCCCEEEEECCCCCCEEEEEEHHHCCCCCEEEEEEECCCCCC
GASHTAAAAHAAGLVDAAVAPAAVASWLRRALDAVAVPARVLPAARTPDRPVRTDADGDR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCC
AGIADNSRADASQAGSGPAPARGGWEQVLAARTGQRRHAGDILDGLFPAGVDLTGPDRTV
CCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHH
RARVGRLAGTPVADGEHSADGELSAGGEPGAGGLGPRAVGVALAAERGGAPGPAGYRLLV
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHEEEHHCCCCCCCHHHHHHH
RAAGLASRLGLPLVTLVDTPGAECGPAAEAGGIAAEIGTAMAEVLGCASPTLSVIVGEGG
HHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCC
SGGALAACCTDVVLMSPDSYVTALSPEGTATTLRISVEQAADTAGLRPSDLVSLGFADGV
CCCHHHHHHHHHEEECCCCEEEEECCCCCEEEEEEEHHHHHHHCCCCHHHHHEECCCCCC
LAPRDTGPPGLAHRVTEVLTELTMRDSDVRLRQRRAKWSTGLGGFL
CCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AERDSTATAQDWRAAVLADVIRRPAVAGAPNRLGWPGYDGRPALWWGTGPVEGVDAVVA
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHH
VWDFAVNGGSFGEADAGAFADAAAEAVAGRRPLVSLVRSGGTRLQEGVAGLVGLARVSLA
HHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LAEVAAAGLPHVAVSDQPTTGGMWVTVGSRADLRCAVLGATVGFAGPRVVAAVTGEAPPA
HHHHHHCCCCCEEECCCCCCCCEEEEECCCCCCEEEEEEHHHCCCCCEEEEEEECCCCCC
GASHTAAAAHAAGLVDAAVAPAAVASWLRRALDAVAVPARVLPAARTPDRPVRTDADGDR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCC
AGIADNSRADASQAGSGPAPARGGWEQVLAARTGQRRHAGDILDGLFPAGVDLTGPDRTV
CCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHH
RARVGRLAGTPVADGEHSADGELSAGGEPGAGGLGPRAVGVALAAERGGAPGPAGYRLLV
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHEEEHHCCCCCCCHHHHHHH
RAAGLASRLGLPLVTLVDTPGAECGPAAEAGGIAAEIGTAMAEVLGCASPTLSVIVGEGG
HHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCC
SGGALAACCTDVVLMSPDSYVTALSPEGTATTLRISVEQAADTAGLRPSDLVSLGFADGV
CCCHHHHHHHHHEEECCCCEEEEECCCCCEEEEEEEHHHHHHHCCCCHHHHHEECCCCCC
LAPRDTGPPGLAHRVTEVLTELTMRDSDVRLRQRRAKWSTGLGGFL
CCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]