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The map label for this gene is sucD [H]

Identifier: 158317721

GI number: 158317721

Start: 7285508

End: 7286380

Strand: Reverse

Name: sucD [H]

Synonym: Franean1_5979

Alternate gene names: 158317721

Gene position: 7286380-7285508 (Counterclockwise)

Preceding gene: 158317722

Following gene: 158317720

Centisome position: 81.12

GC content: 68.38

Gene sequence:

>873_bases
ATGGCTATCTGGCTTGACGAGAACAGCCGCGTGGTGGTGCAGGGCATCACCGGTGGCGAGGGCAGCAAGCACACCCGGCG
GATGCTGGCGGCGGGCACCAAGGTCGTCGCCGGCGTGAACGCGCGCAAGGTCGGCCAGCAGGTCGAGGGGGTCCCGGTCT
TCGGCTCGGTGGCCGACGCCATGGCCGAGACCGGCGCCAACGTCTCGGTGATCTTCGTTCCGCCGAGGTTCACCAAGGAT
GCAGCGATCGAGGCGGTCGACGCCGCGATCCCGCTCGCCGTCGTCATCACCGAGGGCGTGCCGGTGCACGACACAACCGA
GTTCTTCGCCTACTCGCAGTCCAAGGGCACGACCCGGATCATCGGGCCGAACTGCCCCGGAATCGCCAGCCCGGGCGTCT
CCAACGCCGGCATCATCCCCGCCGACATCACGCCGGGCGGGCGGATCGGCCTGGTCAGCAAGAGCGGCACGCTGACCTAC
CAGATGATGTACGAGCTGCGTGAGTTCGGTTTCTCCACCTGCGTCGGCATCGGCGGTGACCCGGTCATCGGGACCACGCA
CATCGACGCCCTCGACGCGTTCCAGGCCGACCCGGGCACCGACGCGATCGTCATGATCGGTGAGATCGGCGGTGACGCGG
AGGAGCGTGCCGCGGCCCACATCGACGCGCACGTGACGAAGCCCGTCGTGGGTTACGTCGCCGGGTTCACCGCCCCGGAA
GGCAAGACCATGGGCCACGCCGGCGCGATCGTCTCGGGCTCCTCGGGTACCGCGCAGGCGAAGAAGGAGGCCCTCGAGAA
GGCCGGTGTGCGTGTCGGCAAGACCCCAACCGAAACGGCGCGACTGATGGCTGACATCATGCGTTCGTTGTAG

Upstream 100 bases:

>100_bases
CTCCCGGTGGTCAAGCCGGTGGACACGATGGACGGCGCAGCGAAGCTCGCCGCCGAGCTCGCCGCGGCCGCGGCCTGACC
TGGGTCGGAGGACACAACCG

Downstream 100 bases:

>100_bases
CTCTGTTCGCGGGGGGTCTTCCTCTGACCTGGGGGAAGGCCCCCGCGTCGGGCGGTCCAGGGGTTCTTTGGGTCGTTGGG
GCGGGGACGCGGACGCGAAC

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MAIWLDENSRVVVQGITGGEGSKHTRRMLAAGTKVVAGVNARKVGQQVEGVPVFGSVADAMAETGANVSVIFVPPRFTKD
AAIEAVDAAIPLAVVITEGVPVHDTTEFFAYSQSKGTTRIIGPNCPGIASPGVSNAGIIPADITPGGRIGLVSKSGTLTY
QMMYELREFGFSTCVGIGGDPVIGTTHIDALDAFQADPGTDAIVMIGEIGGDAEERAAAHIDAHVTKPVVGYVAGFTAPE
GKTMGHAGAIVSGSSGTAQAKKEALEKAGVRVGKTPTETARLMADIMRSL

Sequences:

>Translated_290_residues
MAIWLDENSRVVVQGITGGEGSKHTRRMLAAGTKVVAGVNARKVGQQVEGVPVFGSVADAMAETGANVSVIFVPPRFTKD
AAIEAVDAAIPLAVVITEGVPVHDTTEFFAYSQSKGTTRIIGPNCPGIASPGVSNAGIIPADITPGGRIGLVSKSGTLTY
QMMYELREFGFSTCVGIGGDPVIGTTHIDALDAFQADPGTDAIVMIGEIGGDAEERAAAHIDAHVTKPVVGYVAGFTAPE
GKTMGHAGAIVSGSSGTAQAKKEALEKAGVRVGKTPTETARLMADIMRSL
>Mature_289_residues
AIWLDENSRVVVQGITGGEGSKHTRRMLAAGTKVVAGVNARKVGQQVEGVPVFGSVADAMAETGANVSVIFVPPRFTKDA
AIEAVDAAIPLAVVITEGVPVHDTTEFFAYSQSKGTTRIIGPNCPGIASPGVSNAGIIPADITPGGRIGLVSKSGTLTYQ
MMYELREFGFSTCVGIGGDPVIGTTHIDALDAFQADPGTDAIVMIGEIGGDAEERAAAHIDAHVTKPVVGYVAGFTAPEG
KTMGHAGAIVSGSSGTAQAKKEALEKAGVRVGKTPTETARLMADIMRSL

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=282, Percent_Identity=47.1631205673759, Blast_Score=212, Evalue=3e-55,
Organism=Homo sapiens, GI38569423, Length=256, Percent_Identity=31.640625, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI38569421, Length=256, Percent_Identity=31.640625, Blast_Score=98, Evalue=7e-21,
Organism=Escherichia coli, GI1786949, Length=292, Percent_Identity=52.0547945205479, Blast_Score=286, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI17550194, Length=288, Percent_Identity=48.6111111111111, Blast_Score=244, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI17553126, Length=282, Percent_Identity=45.3900709219858, Blast_Score=217, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI17557344, Length=261, Percent_Identity=29.8850574712644, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17551266, Length=261, Percent_Identity=28.3524904214559, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324716, Length=293, Percent_Identity=43.0034129692833, Blast_Score=216, Evalue=3e-57,
Organism=Drosophila melanogaster, GI21356559, Length=293, Percent_Identity=43.6860068259386, Blast_Score=235, Evalue=3e-62,
Organism=Drosophila melanogaster, GI28574296, Length=294, Percent_Identity=46.9387755102041, Blast_Score=224, Evalue=6e-59,
Organism=Drosophila melanogaster, GI281363477, Length=238, Percent_Identity=30.2521008403361, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI281363475, Length=238, Percent_Identity=30.2521008403361, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI281363473, Length=238, Percent_Identity=30.2521008403361, Blast_Score=88, Evalue=7e-18,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 29701; Mature: 29570

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIWLDENSRVVVQGITGGEGSKHTRRMLAAGTKVVAGVNARKVGQQVEGVPVFGSVADA
CEEEEECCCEEEEEEECCCCCCHHHHHHHHCCCCEEECCCHHHHHHHHCCCCEEHHHHHH
MAETGANVSVIFVPPRFTKDAAIEAVDAAIPLAVVITEGVPVHDTTEFFAYSQSKGTTRI
HHHCCCCEEEEEECCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCHHHEEEECCCCCEEE
IGPNCPGIASPGVSNAGIIPADITPGGRIGLVSKSGTLTYQMMYELREFGFSTCVGIGGD
ECCCCCCCCCCCCCCCCEEECCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEECCCCC
PVIGTTHIDALDAFQADPGTDAIVMIGEIGGDAEERAAAHIDAHVTKPVVGYVAGFTAPE
CEEECCCCHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GKTMGHAGAIVSGSSGTAQAKKEALEKAGVRVGKTPTETARLMADIMRSL
CCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHC
>Mature Secondary Structure 
AIWLDENSRVVVQGITGGEGSKHTRRMLAAGTKVVAGVNARKVGQQVEGVPVFGSVADA
EEEEECCCEEEEEEECCCCCCHHHHHHHHCCCCEEECCCHHHHHHHHCCCCEEHHHHHH
MAETGANVSVIFVPPRFTKDAAIEAVDAAIPLAVVITEGVPVHDTTEFFAYSQSKGTTRI
HHHCCCCEEEEEECCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCHHHEEEECCCCCEEE
IGPNCPGIASPGVSNAGIIPADITPGGRIGLVSKSGTLTYQMMYELREFGFSTCVGIGGD
ECCCCCCCCCCCCCCCCEEECCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEECCCCC
PVIGTTHIDALDAFQADPGTDAIVMIGEIGGDAEERAAAHIDAHVTKPVVGYVAGFTAPE
CEEECCCCHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GKTMGHAGAIVSGSSGTAQAKKEALEKAGVRVGKTPTETARLMADIMRSL
CCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]