Click here to switch to the map view.

The map label for this gene is strD [H]

Identifier: 158317643

GI number: 158317643

Start: 7168025

End: 7169095

Strand: Reverse

Name: strD [H]

Synonym: Franean1_5901

Alternate gene names: 158317643

Gene position: 7169095-7168025 (Counterclockwise)

Preceding gene: 158317648

Following gene: 158317641

Centisome position: 79.82

GC content: 67.69

Gene sequence:

>1071_bases
ATGAAGGCACTCGTGCTCGCCGGTGGCTCCGGGACCCGTCTTCGGCCGATCACCCACACCTCGGCCAAGCAACTCGTGCC
CGTCGCCAACAAGCCGGTGCTGTTCTACGGGCTCGAGGCGATCCGCGGCGCCGGGATCACCGATGTCGGGATCATCGTCG
GCGAGACGGCGGCCGAGATCGAGAACGCGGTTGGTGACGGATCGCAGTTCGGCATCACCGTCACCTACATCCGCCAGGAG
GCGCCGCTCGGTCTGGCACACGCCGTCCTCATCGCGCGGGACTTCCTCGCCGACGAGCCGTTCGTGATGTACCTCGGCGA
CAACATGATCATCGGTGGGATCTCCGGGCTGGTCGAGGAGTTCCGGCACACCACCTCCGATGCGCTCATCCTGCTCACCA
AGGTCGACAACCCCTCGGCGTTCGGCGTCGCCGAGCTGGGAGCGGACGGCCGGATCATCCGGCTCGTCGAGAAGCCCGCC
GACCCGCCGAGCGACCTCGCGCTCGTCGGCGTCTACATGTTCGGTCTCGCGATCCACGAGGCCGTCCGCTCGATCAAGCC
CTCAGGACGCGGCGAGCTCGAGATCACCGAAGCGATCCAGTGGCTCGTGGACGGCGGCTACGACGTCGCGCCGCACCTTG
TCGAGGGCTACTGGAAGGACACCGGCCGGCTCGACGACATGCTGGAGACCAACCGGCACATCCTCGAGTCAATCGAGCCC
GCGATCCACGGCACCGTGGACGAGCACAGCACCATCGTCGGCCGGGTGGTGATCGAGGAGGGTGCGTCCCTGGTGCGCTC
GACGGTGCGCGGCCCGGCGATCATCGGCCGCGGCACCCGGCTCGTCGACACCTACGTAGGCCCCTTCACCTCGATCTACC
ACTCGTGCGTCGTCGAACGAACCGAGATCGAGTACTCGATCGTGCTCGAGCGGGCCACCATCCGCGGCATCGGCCGCATC
GAGGACTCCCTGATCGGGCGGGACGCCGAGGTCGTACCGTCGAGCGCTCTCCCCAAGGCGCACCGCCTGATGATCGGCGA
TCACTCCCGGGTCTCGGTCGCAACGAGCTAG

Upstream 100 bases:

>100_bases
GGAAGGCCGACGTGGGCATCTGGCTGTGGCGTGCATCACGTTTTGGTTACTTTCCGTCAGGGCCTGTCTCCTGGAGCGAC
CCACGATAGGGTTTCGGATC

Downstream 100 bases:

>100_bases
CAGCTGGGAGGCGGTCAGCCGGCAGGCGTGCTGACGGAAGCGCGGTCGCGCAGGGCCGGGATGAGGGCCAGCGTGAGGGC
GGTGATCCAGAGCAGCGCCG

Product: glucose-1-phosphate thymidyltransferase

Products: NA

Alternate protein names: Sugar-nucleotidylation enzyme; dTDP-glucose pyrophosphorylase; dTDP-glucose synthase [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MKALVLAGGSGTRLRPITHTSAKQLVPVANKPVLFYGLEAIRGAGITDVGIIVGETAAEIENAVGDGSQFGITVTYIRQE
APLGLAHAVLIARDFLADEPFVMYLGDNMIIGGISGLVEEFRHTTSDALILLTKVDNPSAFGVAELGADGRIIRLVEKPA
DPPSDLALVGVYMFGLAIHEAVRSIKPSGRGELEITEAIQWLVDGGYDVAPHLVEGYWKDTGRLDDMLETNRHILESIEP
AIHGTVDEHSTIVGRVVIEEGASLVRSTVRGPAIIGRGTRLVDTYVGPFTSIYHSCVVERTEIEYSIVLERATIRGIGRI
EDSLIGRDAEVVPSSALPKAHRLMIGDHSRVSVATS

Sequences:

>Translated_356_residues
MKALVLAGGSGTRLRPITHTSAKQLVPVANKPVLFYGLEAIRGAGITDVGIIVGETAAEIENAVGDGSQFGITVTYIRQE
APLGLAHAVLIARDFLADEPFVMYLGDNMIIGGISGLVEEFRHTTSDALILLTKVDNPSAFGVAELGADGRIIRLVEKPA
DPPSDLALVGVYMFGLAIHEAVRSIKPSGRGELEITEAIQWLVDGGYDVAPHLVEGYWKDTGRLDDMLETNRHILESIEP
AIHGTVDEHSTIVGRVVIEEGASLVRSTVRGPAIIGRGTRLVDTYVGPFTSIYHSCVVERTEIEYSIVLERATIRGIGRI
EDSLIGRDAEVVPSSALPKAHRLMIGDHSRVSVATS
>Mature_356_residues
MKALVLAGGSGTRLRPITHTSAKQLVPVANKPVLFYGLEAIRGAGITDVGIIVGETAAEIENAVGDGSQFGITVTYIRQE
APLGLAHAVLIARDFLADEPFVMYLGDNMIIGGISGLVEEFRHTTSDALILLTKVDNPSAFGVAELGADGRIIRLVEKPA
DPPSDLALVGVYMFGLAIHEAVRSIKPSGRGELEITEAIQWLVDGGYDVAPHLVEGYWKDTGRLDDMLETNRHILESIEP
AIHGTVDEHSTIVGRVVIEEGASLVRSTVRGPAIIGRGTRLVDTYVGPFTSIYHSCVVERTEIEYSIVLERATIRGIGRI
EDSLIGRDAEVVPSSALPKAHRLMIGDHSRVSVATS

Specific function: Involved in the biosynthesis of the streptose moiety of streptomycin. Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis [H]

COG id: COG1209

COG function: function code M; dTDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-1-phosphate thymidylyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=356, Percent_Identity=30.0561797752809, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI11761619, Length=335, Percent_Identity=29.8507462686567, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI31881779, Length=358, Percent_Identity=24.3016759776536, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI45447090, Length=358, Percent_Identity=24.3016759776536, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1790224, Length=239, Percent_Identity=39.7489539748954, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1788351, Length=236, Percent_Identity=36.0169491525424, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1788355, Length=263, Percent_Identity=24.3346007604563, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787488, Length=261, Percent_Identity=26.0536398467433, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI133931050, Length=360, Percent_Identity=27.5, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17509979, Length=341, Percent_Identity=24.3401759530792, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320148, Length=336, Percent_Identity=27.0833333333333, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21355443, Length=334, Percent_Identity=27.8443113772455, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24644084, Length=334, Percent_Identity=27.8443113772455, Blast_Score=115, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005908
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.24 [H]

Molecular weight: Translated: 38155; Mature: 38155

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALVLAGGSGTRLRPITHTSAKQLVPVANKPVLFYGLEAIRGAGITDVGIIVGETAAEI
CCEEEEECCCCCEEEEECCCCHHHCCCCCCCCEEEEEHHHHCCCCCCEEEEEECCHHHHH
ENAVGDGSQFGITVTYIRQEAPLGLAHAVLIARDFLADEPFVMYLGDNMIIGGISGLVEE
HHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCEEEECHHHHHHH
FRHTTSDALILLTKVDNPSAFGVAELGADGRIIRLVEKPADPPSDLALVGVYMFGLAIHE
HHCCCCCEEEEEEECCCCCCCCHHEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
AVRSIKPSGRGELEITEAIQWLVDGGYDVAPHLVEGYWKDTGRLDDMLETNRHILESIEP
HHHHCCCCCCCCEEHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AIHGTVDEHSTIVGRVVIEEGASLVRSTVRGPAIIGRGTRLVDTYVGPFTSIYHSCVVER
HHCCCCCCCCHHEEHHHHHHHHHHHHHHHCCCEEECCCCEEEHHHHCHHHHHHHHHHHHH
TEIEYSIVLERATIRGIGRIEDSLIGRDAEVVPSSALPKAHRLMIGDHSRVSVATS
CCCEEEEEEEHHHHCCCCHHHHHHCCCCCCCCCCCCCCHHHEEEECCCCCEEEECC
>Mature Secondary Structure
MKALVLAGGSGTRLRPITHTSAKQLVPVANKPVLFYGLEAIRGAGITDVGIIVGETAAEI
CCEEEEECCCCCEEEEECCCCHHHCCCCCCCCEEEEEHHHHCCCCCCEEEEEECCHHHHH
ENAVGDGSQFGITVTYIRQEAPLGLAHAVLIARDFLADEPFVMYLGDNMIIGGISGLVEE
HHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCEEEECHHHHHHH
FRHTTSDALILLTKVDNPSAFGVAELGADGRIIRLVEKPADPPSDLALVGVYMFGLAIHE
HHCCCCCEEEEEEECCCCCCCCHHEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
AVRSIKPSGRGELEITEAIQWLVDGGYDVAPHLVEGYWKDTGRLDDMLETNRHILESIEP
HHHHCCCCCCCCEEHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AIHGTVDEHSTIVGRVVIEEGASLVRSTVRGPAIIGRGTRLVDTYVGPFTSIYHSCVVER
HHCCCCCCCCHHEEHHHHHHHHHHHHHHHCCCEEECCCCEEEHHHHCHHHHHHHHHHHHH
TEIEYSIVLERATIRGIGRIEDSLIGRDAEVVPSSALPKAHRLMIGDHSRVSVATS
CCCEEEEEEEHHHHCCCCHHHHHHCCCCCCCCCCCCCCHHHEEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3118332 [H]