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The map label for this gene is mpg1 [H]

Identifier: 158317620

GI number: 158317620

Start: 7133234

End: 7134307

Strand: Reverse

Name: mpg1 [H]

Synonym: Franean1_5876

Alternate gene names: 158317620

Gene position: 7134307-7133234 (Counterclockwise)

Preceding gene: 158317621

Following gene: 158317615

Centisome position: 79.43

GC content: 73.37

Gene sequence:

>1074_bases
ATGGACGCAGTGATGCTGGTCGGCGGGCAGGGAACCCGTCTTCGCCCGTTGACGATGTCGGCGCCGAAGCCGATGTTGCC
GGTCGCCGGCGTGCCGGTGACGGCCCACATGCTCGCCCGTGCCCGCGACGCGGGAATCACCCGGGTGGTCCTCGCCACCT
CGTACCGGGCCGAGGTCTTCGAGGAGCACTTCGGTGACGGTTCCGGGCACGGTCTCGAACTCGAATACGTCACCGAGACC
GAGCCGCTGGGTACCGGCGGCGCCATCCGCAACGTCGCCAGCCGGCTGCGCTCCGGCGCCGACGAGCCGGTGGTCATCTT
CAACGGCGACATCCTCTCCGGCCTCGACATCGGCGCCCTCGTCGAGCGGCACACCACCGCCGACGCGGCCGTCACCCTCC
ACCTCACCAGGGTCGACGACCCGCGGGCCTTCGGTGTCGTCCCGACCGACCCCGCCGGCCGGGTCACCGCCTTCCTCGAG
AAGACCCCCGATCCCCCCACCAACCTCATCAACGCCGGCTGCTACGTCTTCCGCCGCTCGCTCATCGACACCATCCCCGC
GGGACGTCCGGTCTCGGTCGAGCGGGAGACCTTCCCGTCCCTGCTCGCCGCCGGGGTGCCGGTGGTCGGCTACCCGGACG
ACACCTACTGGCTCGACCTCGGGACCCCGGCGGCGTTCGTCCTGGGCTCGCGGGACCTCGTCACCGGGCGGATGCCGTCC
TCGGCGCTGCCCGGCCCGGTCGGGGACCGCCTCGTGCTGCCCGGGTCCACGGTGGCCACCGACGCCAAGATCGGCGGCGG
CTCGACGATCGGGGCGGGTGCCTCGGTCGGCACCGGCGCGCGCATCGATGGCTCGGTGCTGTTCGACCGGGCGTCCGTCG
GGGCGGGCGCGTACGTGCGTGACAGCGTCGTCGGCCGCGAGGCGGTGATCGGCAACGGGGTGGTGCTCGAGAACGTCGTC
ATCGGCGACGGCGCCGTGATCGAGCCGGGCAACGAGCTGCGCGCCGGGGCCAGGGTGTTCCCGGGCGCGGTGCTCGGCGC
CGGCGCCGTCCGGTTCAGCTCCGACCGGGCCTGA

Upstream 100 bases:

>100_bases
CGACGATGCGTGTCCAGCCTGTGGCCTCTCGTTGAGCATGGGGGTCACCCGGCCGGGCACACGCAACCGACTCGGACGTG
CTCTGCGACACTGACGCCCC

Downstream 100 bases:

>100_bases
CCTCCCGGCCGACCGGGCGGCTTCAGCTCCGACCGAGCCTGACCTCCCGGCCGGCCGACCAGGCGACCTCCACGCACACC
TGACCGTCGTCGGCGTCCGC

Product: nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MDAVMLVGGQGTRLRPLTMSAPKPMLPVAGVPVTAHMLARARDAGITRVVLATSYRAEVFEEHFGDGSGHGLELEYVTET
EPLGTGGAIRNVASRLRSGADEPVVIFNGDILSGLDIGALVERHTTADAAVTLHLTRVDDPRAFGVVPTDPAGRVTAFLE
KTPDPPTNLINAGCYVFRRSLIDTIPAGRPVSVERETFPSLLAAGVPVVGYPDDTYWLDLGTPAAFVLGSRDLVTGRMPS
SALPGPVGDRLVLPGSTVATDAKIGGGSTIGAGASVGTGARIDGSVLFDRASVGAGAYVRDSVVGREAVIGNGVVLENVV
IGDGAVIEPGNELRAGARVFPGAVLGAGAVRFSSDRA

Sequences:

>Translated_357_residues
MDAVMLVGGQGTRLRPLTMSAPKPMLPVAGVPVTAHMLARARDAGITRVVLATSYRAEVFEEHFGDGSGHGLELEYVTET
EPLGTGGAIRNVASRLRSGADEPVVIFNGDILSGLDIGALVERHTTADAAVTLHLTRVDDPRAFGVVPTDPAGRVTAFLE
KTPDPPTNLINAGCYVFRRSLIDTIPAGRPVSVERETFPSLLAAGVPVVGYPDDTYWLDLGTPAAFVLGSRDLVTGRMPS
SALPGPVGDRLVLPGSTVATDAKIGGGSTIGAGASVGTGARIDGSVLFDRASVGAGAYVRDSVVGREAVIGNGVVLENVV
IGDGAVIEPGNELRAGARVFPGAVLGAGAVRFSSDRA
>Mature_357_residues
MDAVMLVGGQGTRLRPLTMSAPKPMLPVAGVPVTAHMLARARDAGITRVVLATSYRAEVFEEHFGDGSGHGLELEYVTET
EPLGTGGAIRNVASRLRSGADEPVVIFNGDILSGLDIGALVERHTTADAAVTLHLTRVDDPRAFGVVPTDPAGRVTAFLE
KTPDPPTNLINAGCYVFRRSLIDTIPAGRPVSVERETFPSLLAAGVPVVGYPDDTYWLDLGTPAAFVLGSRDLVTGRMPS
SALPGPVGDRLVLPGSTVATDAKIGGGSTIGAGASVGTGARIDGSVLFDRASVGAGAYVRDSVVGREAVIGNGVVLENVV
IGDGAVIEPGNELRAGARVFPGAVLGAGAVRFSSDRA

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=355, Percent_Identity=30.7042253521127, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI11761619, Length=323, Percent_Identity=30.3405572755418, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI31881779, Length=354, Percent_Identity=26.5536723163842, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI45447090, Length=354, Percent_Identity=26.5536723163842, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1788351, Length=242, Percent_Identity=26.8595041322314, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789837, Length=372, Percent_Identity=25.8064516129032, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790224, Length=193, Percent_Identity=30.0518134715026, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI133931050, Length=359, Percent_Identity=34.8189415041783, Blast_Score=187, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17509979, Length=336, Percent_Identity=27.6785714285714, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17509981, Length=325, Percent_Identity=26.4615384615385, Blast_Score=113, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320148, Length=351, Percent_Identity=32.1937321937322, Blast_Score=178, Evalue=1e-45,
Organism=Drosophila melanogaster, GI21355443, Length=359, Percent_Identity=34.5403899721448, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24644084, Length=359, Percent_Identity=34.5403899721448, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24653912, Length=369, Percent_Identity=25.2032520325203, Blast_Score=101, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 36651; Mature: 36651

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAVMLVGGQGTRLRPLTMSAPKPMLPVAGVPVTAHMLARARDAGITRVVLATSYRAEVF
CCEEEEECCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHH
EEHFGDGSGHGLELEYVTETEPLGTGGAIRNVASRLRSGADEPVVIFNGDILSGLDIGAL
HHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCEECCCCHHHH
VERHTTADAAVTLHLTRVDDPRAFGVVPTDPAGRVTAFLEKTPDPPTNLINAGCYVFRRS
HHHCCCCCEEEEEEEEECCCCCEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
LIDTIPAGRPVSVERETFPSLLAAGVPVVGYPDDTYWLDLGTPAAFVLGSRDLVTGRMPS
HHHHCCCCCCCEECHHHHHHHHHCCCCEEECCCCCEEEECCCCEEEEECCCCEEECCCCC
SALPGPVGDRLVLPGSTVATDAKIGGGSTIGAGASVGTGARIDGSVLFDRASVGAGAYVR
CCCCCCCCCEEEECCCCEECCCCCCCCCCCCCCCCCCCCCEECCEEEEEECCCCCCCCHH
DSVVGREAVIGNGVVLENVVIGDGAVIEPGNELRAGARVFPGAVLGAGAVRFSSDRA
HHHCCCHHEECCCEEEEEEEECCCCEECCCHHHCCCCEECCCHHCCCCEEEECCCCC
>Mature Secondary Structure
MDAVMLVGGQGTRLRPLTMSAPKPMLPVAGVPVTAHMLARARDAGITRVVLATSYRAEVF
CCEEEEECCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHH
EEHFGDGSGHGLELEYVTETEPLGTGGAIRNVASRLRSGADEPVVIFNGDILSGLDIGAL
HHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCEECCCCHHHH
VERHTTADAAVTLHLTRVDDPRAFGVVPTDPAGRVTAFLEKTPDPPTNLINAGCYVFRRS
HHHCCCCCEEEEEEEEECCCCCEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
LIDTIPAGRPVSVERETFPSLLAAGVPVVGYPDDTYWLDLGTPAAFVLGSRDLVTGRMPS
HHHHCCCCCCCEECHHHHHHHHHCCCCEEECCCCCEEEECCCCEEEEECCCCEEECCCCC
SALPGPVGDRLVLPGSTVATDAKIGGGSTIGAGASVGTGARIDGSVLFDRASVGAGAYVR
CCCCCCCCCEEEECCCCEECCCCCCCCCCCCCCCCCCCCCEECCEEEEEECCCCCCCCHH
DSVVGREAVIGNGVVLENVVIGDGAVIEPGNELRAGARVFPGAVLGAGAVRFSSDRA
HHHCCCHHEECCCEEEEEEEECCCCEECCCHHHCCCCEECCCHHCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]