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The map label for this gene is fdhA [H]

Identifier: 158317546

GI number: 158317546

Start: 7045005

End: 7047311

Strand: Reverse

Name: fdhA [H]

Synonym: Franean1_5802

Alternate gene names: 158317546

Gene position: 7047311-7045005 (Counterclockwise)

Preceding gene: 158317547

Following gene: 158317545

Centisome position: 78.46

GC content: 74.21

Gene sequence:

>2307_bases
ATGATGAAGAGAACAAGCGCGGGTACGGGTACGGGAACGGCCGCCGGCTCGGTGACTGCCCTGCGGGTCTGCCCGCTGTG
CGAGGCGACCTGTGGACTGGAGCTACGGATCACGGACGGCCGGGTGACGGCCGCCCGTGGCGACGCGGAACATGTGTTCA
GCCGTGGCTACCTCTGCGCCAAAGGAGCCTCCCTGCCGCAGTTACTCGGCGACCCCGACCGGCTTCGCCGTCCGCTGCTG
CGCGACCGGGCCACCGGTGAGCACCGTGAGGTCGACTGGGAGAAGGCGTTCGCAGCCGTCCACGCCGGGCTGCGGCGGGT
GGTCTCCGCCCATGGCCCGGCCGTGGTCGCGGCCTATCTCGGCAATCCGAACGCGCACTCGATGGCCGGCGCCCAGCACA
GGCCGGCGTTCACCCAGGCGCTGCGGACCCGCGCCGTGTTCAGCGCCTCCACGGTCGACCAGATGCCCATGCACGTCGCA
TGCGGCCTCGTCTTCGGTCACCCCTCGCTCATCCCGGTGCCCGATCTGGACCGCACCGACCACCTGCTGATGCTCGGTGC
CAATCCGGCGGTGTCCAACGGCAGTCTGTGCACGGCGCCGGACTTCCCCGGCCGGCTGGCTGGAATCCGCGCGCGTGGCG
GGCGGGTCGTCGTCGTCGACCCACGCCGCACCCGCACGGCCGCCCTCGCCGACGAGCACCTGCCGATCCGGCCCGGGACG
GACGCGCTGTGGCTGTTCGCGATCGTCAACGTCCTCGCCGCCGAGGGGCTCGTCCGCCTCGGCCCGCTCGCCGCGCACCT
GTCCGGAGCGGACAGCGTCGCCGAGCTTGCCGCGCCGTTCACCCCGGAGCGGGTCGCCGCGAGCTGCGGAATCCCGGCCG
AGACGACCCGGCGGACTGCTCGCGAGCTCGCCGCCGCGCCGCGAGCCGCCGTCTACGGGCGGATGGGCACGACCACGGTC
GAGTTCGGCACCCTGACCAGCTGGCTGACGATCGCCCTCAACGCGATCACCGGCAATCTCGACGTCCCGGGCGGCGCCAT
GTTCGGCCGGGGTGCGCACGGCCGCGCCGACCGCGTGGGCGGCGGGCGGGGCGGCGGGCGCGGGTGGCGCACCGGGCGCT
GGCACACCCGCGTCCGCGGTCTGCCGGAGGTGATGGGCGAGCTGCCGGCCGCGGCGCTGGCCGAGGAGATGGACACCCCC
GGAGACGGCCGCCTACGGGCGCTGTTCACCATCGCGGGCAACCCGGCGCTCTCCACACCGGACTCCGCCAGGCTCGCCGC
GGCACTGGCCCAGCTGGACTTCATGGTGAGCGTCGATCCGTACCTCAACGAGACGTCCCGGCACGCCGACGTGGTGCTGC
CGCCGGCTGATCCGGCCGGGGTCGGGCACTACGACTTCGCGCTCGGCGCGCTGGCGGTGCGCACCGTGGCGACCTATTCG
CCGCCGGCGCTGCCGCCGTACCCGGGCGGGATGGCCGAGCACGACATCCTGGCCCGCCTCACCCTCATCGCCCTGGCTCT
CGCCGACGAGCCGGCCAACGCTGCCACCACAGCCACCGCCGGGCCGGCCACCACCGCTGAATCAGGCACCACCGCCGAGC
CGGCCGATGTCGACGCGACAGCCGACGCGGAGCTGCCGGTCGAGGACTCCCGGCCAGCCGATGCCGCGGTCTGGACCGAC
ACCGCCGTCGCGGCCTTCCACGAGTACCTGATCGAGGAGGCACTGCGGCGGGCGGTCACGGAGCCCGGCTCACCTGTCGC
CGGGCGGGACGTCGCCGAACTGGGCGCTCTCGTGGACGGCGACGGCGCACCGGAACGCCTACTCGACATCGCGCTTCGCA
CCGGGCACTTCGGTGACGCGTTCGGTGCGCGGCCCGGCGGGCTGAGCCTGGCCACGCTGCGGGCGAACCCGCACGGGATC
GATCTGGGACCGCTCGAGCCGCGGATCCCGGCAATGCTGCGGACGGCCAGCGCGACGGTGGAGCTGTGCCCCGACCCGAT
CGTGGCCGACGCCGCCCGCCTGCACGCCGCCCTCGACGCCCACGAGGCGGCTGAGGGCCGCGAGCCCTCCATGACCCCGG
GTTCCCCAGAGGCACCGGAGAGCCCGGGCAGCCCGGGACTGACCCTGATTGGCCGGCGTCACCTGCGGACGAACAACAGC
TGGCTGCACAACGTCCCGGAGATGGCCCGGGGACGAGATCGCTGCACCCTGCTGGTGCACCCCGACGACGCCGCCCGCCA
CGGCGTCCGCGACGGCGGGTCAGCCCGGATCACGTCCACCGCCGGCTCCCTCGACGTCCGGGTGTAG

Upstream 100 bases:

>100_bases
GAACGTACTCGTTCCTCGTCGGATCCGCCTGATCGGAAGCGTCCGTACACCAGGGCGCACCACCCGGAATGTGCGCCGGG
AATATGTGATCCTGCCGGAC

Downstream 100 bases:

>100_bases
GTCAGCGACGAGATGATGGCCGGTGTCGTGTGCCTGCCGCACGGCTGGGGCCACGGCCTCGCCGGCACCCGGATGTCGGT
CGCCGCCGGACACCCCGGAG

Product: molybdopterin oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 768; Mature: 768

Protein sequence:

>768_residues
MMKRTSAGTGTGTAAGSVTALRVCPLCEATCGLELRITDGRVTAARGDAEHVFSRGYLCAKGASLPQLLGDPDRLRRPLL
RDRATGEHREVDWEKAFAAVHAGLRRVVSAHGPAVVAAYLGNPNAHSMAGAQHRPAFTQALRTRAVFSASTVDQMPMHVA
CGLVFGHPSLIPVPDLDRTDHLLMLGANPAVSNGSLCTAPDFPGRLAGIRARGGRVVVVDPRRTRTAALADEHLPIRPGT
DALWLFAIVNVLAAEGLVRLGPLAAHLSGADSVAELAAPFTPERVAASCGIPAETTRRTARELAAAPRAAVYGRMGTTTV
EFGTLTSWLTIALNAITGNLDVPGGAMFGRGAHGRADRVGGGRGGGRGWRTGRWHTRVRGLPEVMGELPAAALAEEMDTP
GDGRLRALFTIAGNPALSTPDSARLAAALAQLDFMVSVDPYLNETSRHADVVLPPADPAGVGHYDFALGALAVRTVATYS
PPALPPYPGGMAEHDILARLTLIALALADEPANAATTATAGPATTAESGTTAEPADVDATADAELPVEDSRPADAAVWTD
TAVAAFHEYLIEEALRRAVTEPGSPVAGRDVAELGALVDGDGAPERLLDIALRTGHFGDAFGARPGGLSLATLRANPHGI
DLGPLEPRIPAMLRTASATVELCPDPIVADAARLHAALDAHEAAEGREPSMTPGSPEAPESPGSPGLTLIGRRHLRTNNS
WLHNVPEMARGRDRCTLLVHPDDAARHGVRDGGSARITSTAGSLDVRV

Sequences:

>Translated_768_residues
MMKRTSAGTGTGTAAGSVTALRVCPLCEATCGLELRITDGRVTAARGDAEHVFSRGYLCAKGASLPQLLGDPDRLRRPLL
RDRATGEHREVDWEKAFAAVHAGLRRVVSAHGPAVVAAYLGNPNAHSMAGAQHRPAFTQALRTRAVFSASTVDQMPMHVA
CGLVFGHPSLIPVPDLDRTDHLLMLGANPAVSNGSLCTAPDFPGRLAGIRARGGRVVVVDPRRTRTAALADEHLPIRPGT
DALWLFAIVNVLAAEGLVRLGPLAAHLSGADSVAELAAPFTPERVAASCGIPAETTRRTARELAAAPRAAVYGRMGTTTV
EFGTLTSWLTIALNAITGNLDVPGGAMFGRGAHGRADRVGGGRGGGRGWRTGRWHTRVRGLPEVMGELPAAALAEEMDTP
GDGRLRALFTIAGNPALSTPDSARLAAALAQLDFMVSVDPYLNETSRHADVVLPPADPAGVGHYDFALGALAVRTVATYS
PPALPPYPGGMAEHDILARLTLIALALADEPANAATTATAGPATTAESGTTAEPADVDATADAELPVEDSRPADAAVWTD
TAVAAFHEYLIEEALRRAVTEPGSPVAGRDVAELGALVDGDGAPERLLDIALRTGHFGDAFGARPGGLSLATLRANPHGI
DLGPLEPRIPAMLRTASATVELCPDPIVADAARLHAALDAHEAAEGREPSMTPGSPEAPESPGSPGLTLIGRRHLRTNNS
WLHNVPEMARGRDRCTLLVHPDDAARHGVRDGGSARITSTAGSLDVRV
>Mature_768_residues
MMKRTSAGTGTGTAAGSVTALRVCPLCEATCGLELRITDGRVTAARGDAEHVFSRGYLCAKGASLPQLLGDPDRLRRPLL
RDRATGEHREVDWEKAFAAVHAGLRRVVSAHGPAVVAAYLGNPNAHSMAGAQHRPAFTQALRTRAVFSASTVDQMPMHVA
CGLVFGHPSLIPVPDLDRTDHLLMLGANPAVSNGSLCTAPDFPGRLAGIRARGGRVVVVDPRRTRTAALADEHLPIRPGT
DALWLFAIVNVLAAEGLVRLGPLAAHLSGADSVAELAAPFTPERVAASCGIPAETTRRTARELAAAPRAAVYGRMGTTTV
EFGTLTSWLTIALNAITGNLDVPGGAMFGRGAHGRADRVGGGRGGGRGWRTGRWHTRVRGLPEVMGELPAAALAEEMDTP
GDGRLRALFTIAGNPALSTPDSARLAAALAQLDFMVSVDPYLNETSRHADVVLPPADPAGVGHYDFALGALAVRTVATYS
PPALPPYPGGMAEHDILARLTLIALALADEPANAATTATAGPATTAESGTTAEPADVDATADAELPVEDSRPADAAVWTD
TAVAAFHEYLIEEALRRAVTEPGSPVAGRDVAELGALVDGDGAPERLLDIALRTGHFGDAFGARPGGLSLATLRANPHGI
DLGPLEPRIPAMLRTASATVELCPDPIVADAARLHAALDAHEAAEGREPSMTPGSPEAPESPGSPGLTLIGRRHLRTNNS
WLHNVPEMARGRDRCTLLVHPDDAARHGVRDGGSARITSTAGSLDVRV

Specific function: Catalyzes the oxidation of formate [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868721, Length=459, Percent_Identity=24.1830065359477, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI171474008, Length=488, Percent_Identity=23.9754098360656, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1787870, Length=475, Percent_Identity=22.9473684210526, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1788534, Length=499, Percent_Identity=22.6452905811623, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI145693196, Length=432, Percent_Identity=23.3796296296296, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI3868720, Length=249, Percent_Identity=26.9076305220884, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI3868719, Length=256, Percent_Identity=25, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006478
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 79834; Mature: 79834

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKRTSAGTGTGTAAGSVTALRVCPLCEATCGLELRITDGRVTAARGDAEHVFSRGYLCA
CCCCCCCCCCCCCCCCCEEEEEECCHHHHHCCEEEEEECCEEEECCCCHHHHHHCCCEEE
KGASLPQLLGDPDRLRRPLLRDRATGEHREVDWEKAFAAVHAGLRRVVSAHGPAVVAAYL
CCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEC
GNPNAHSMAGAQHRPAFTQALRTRAVFSASTVDQMPMHVACGLVFGHPSLIPVPDLDRTD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCCCCCCCCCCCC
HLLMLGANPAVSNGSLCTAPDFPGRLAGIRARGGRVVVVDPRRTRTAALADEHLPIRPGT
CEEEEECCCCCCCCCEEECCCCCCHHEEEEECCCEEEEECCCCCCHHHHHCCCCCCCCCC
DALWLFAIVNVLAAEGLVRLGPLAAHLSGADSVAELAAPFTPERVAASCGIPAETTRRTA
CHHHHHHHHHHHHHCCHHHHCHHHHHCCCCHHHHHHHCCCCHHHHHHHCCCCHHHHHHHH
RELAAAPRAAVYGRMGTTTVEFGTLTSWLTIALNAITGNLDVPGGAMFGRGAHGRADRVG
HHHHHCCCHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCC
GGRGGGRGWRTGRWHTRVRGLPEVMGELPAAALAEEMDTPGDGRLRALFTIAGNPALSTP
CCCCCCCCCCCCCHHHHHCCHHHHHHHCCHHHHHHHHCCCCCCCEEEEEEEECCCCCCCC
DSARLAAALAQLDFMVSVDPYLNETSRHADVVLPPADPAGVGHYDFALGALAVRTVATYS
CHHHHHHHHHHHHEEEECCHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCC
PPALPPYPGGMAEHDILARLTLIALALADEPANAATTATAGPATTAESGTTAEPADVDAT
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ADAELPVEDSRPADAAVWTDTAVAAFHEYLIEEALRRAVTEPGSPVAGRDVAELGALVDG
CCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCEECC
DGAPERLLDIALRTGHFGDAFGARPGGLSLATLRANPHGIDLGPLEPRIPAMLRTASATV
CCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCCCEE
ELCPDPIVADAARLHAALDAHEAAEGREPSMTPGSPEAPESPGSPGLTLIGRRHLRTNNS
EECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHCCCCC
WLHNVPEMARGRDRCTLLVHPDDAARHGVRDGGSARITSTAGSLDVRV
HHHCCHHHHCCCCCEEEEECCCHHHHCCCCCCCCEEEEECCCCEEECC
>Mature Secondary Structure
MMKRTSAGTGTGTAAGSVTALRVCPLCEATCGLELRITDGRVTAARGDAEHVFSRGYLCA
CCCCCCCCCCCCCCCCCEEEEEECCHHHHHCCEEEEEECCEEEECCCCHHHHHHCCCEEE
KGASLPQLLGDPDRLRRPLLRDRATGEHREVDWEKAFAAVHAGLRRVVSAHGPAVVAAYL
CCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEC
GNPNAHSMAGAQHRPAFTQALRTRAVFSASTVDQMPMHVACGLVFGHPSLIPVPDLDRTD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCCCCCCCCCCCC
HLLMLGANPAVSNGSLCTAPDFPGRLAGIRARGGRVVVVDPRRTRTAALADEHLPIRPGT
CEEEEECCCCCCCCCEEECCCCCCHHEEEEECCCEEEEECCCCCCHHHHHCCCCCCCCCC
DALWLFAIVNVLAAEGLVRLGPLAAHLSGADSVAELAAPFTPERVAASCGIPAETTRRTA
CHHHHHHHHHHHHHCCHHHHCHHHHHCCCCHHHHHHHCCCCHHHHHHHCCCCHHHHHHHH
RELAAAPRAAVYGRMGTTTVEFGTLTSWLTIALNAITGNLDVPGGAMFGRGAHGRADRVG
HHHHHCCCHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCC
GGRGGGRGWRTGRWHTRVRGLPEVMGELPAAALAEEMDTPGDGRLRALFTIAGNPALSTP
CCCCCCCCCCCCCHHHHHCCHHHHHHHCCHHHHHHHHCCCCCCCEEEEEEEECCCCCCCC
DSARLAAALAQLDFMVSVDPYLNETSRHADVVLPPADPAGVGHYDFALGALAVRTVATYS
CHHHHHHHHHHHHEEEECCHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCC
PPALPPYPGGMAEHDILARLTLIALALADEPANAATTATAGPATTAESGTTAEPADVDAT
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ADAELPVEDSRPADAAVWTDTAVAAFHEYLIEEALRRAVTEPGSPVAGRDVAELGALVDG
CCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCEECC
DGAPERLLDIALRTGHFGDAFGARPGGLSLATLRANPHGIDLGPLEPRIPAMLRTASATV
CCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCCCEE
ELCPDPIVADAARLHAALDAHEAAEGREPSMTPGSPEAPESPGSPGLTLIGRRHLRTNNS
EECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHCCCCC
WLHNVPEMARGRDRCTLLVHPDDAARHGVRDGGSARITSTAGSLDVRV
HHHCCHHHHCCCCCEEEEECCCHHHHCCCCCCCCEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]