Click here to switch to the map view.

The map label for this gene is fabH3 [H]

Identifier: 158317504

GI number: 158317504

Start: 6994189

End: 6995229

Strand: Reverse

Name: fabH3 [H]

Synonym: Franean1_5756

Alternate gene names: 158317504

Gene position: 6995229-6994189 (Counterclockwise)

Preceding gene: 158317505

Following gene: 158317503

Centisome position: 77.88

GC content: 76.18

Gene sequence:

>1041_bases
GTGAGCGCGGTCCCGGCCACGCCGCGCGGGCGGGCGGCGGTGATCGCCGGCGTCGGCGGGTACGTCCCCCCGAACGTCGT
CACCAACGACGACCTCGCTGCCCGCCTCGACACCTCCGACGAGTGGATCCGCAGCCGCACCGGGATCGCCGCACGCAACG
TGGTGTCCCCTGGGACGGCGACGTCGGACCTCGCCGTCGAGGCGGGCCGCCGCGCGTTGGAGTCCGCCGGCGTGGCCGAG
GCGGGCGCGGTCGTGCTGGCCACGACCACGCCCGACCGGCCCTGCCCGGCGACGGCGCCCGAGGTCGCGAGCCGCCTCGG
GCTCGGTGGCGCGGCCGCGTTCGACATCGCTTCGGTGTGCAGCGGATTCCTCTACGCGCTGGCCGTCGGCGCCGGCCTGA
TCGCGACTGGCGTCGCGGAGCGGGTCCTGGTGGTCGGCGCGGACGCCTTCACGACCATCATAGACCCGCAGGACCGGGGC
ACCGCCGTAATCTTCGCCGACGGGGCGGGCGCGGTGGTGCTCCGCGCCGGCGAGCCGACCGAGGCGGGGGTGGTCGGCAC
CGTCGTGCTGGGCAGCGACGGTGCCCGCAGCGACCTCATCGAAGTGCCGGGGGGAGGCTCCCGGCACCGCTCGTCCCACG
CCGCCACCGGCGACGGCGCCGATCTGGGCGACCCGTACTTCCGGATGCGGGGACGCGAGACGTACCGGCACGCGGTGGAA
CGGATGACGTCGGCGTCGCGGCAGGCCGCGGCGGCCGCCGGCTGGGACGTCTCCCGAGACGTCGACCGCTTCGCCGCACA
CCAGGCCAACGCCCGGATCCTGGCGGCGGTCGCCGACCGGCTCGGTGTCCGCCCGCAGCGACGGCTGTCCAACATCGAGC
AGGTGGGCAACACCGGCGCCGCCTCCGTCCCGTTGCTGCTGGCCGAGGCGACGGCCGCCGGGGCGTTGACGGCCGGGCAC
CGACTGCTGCTCACCGCCTTCGGTGGCGGTCTGGCCTGGGGCGCGACGGCGTTGGTGTGGCCAGACGTCAAGGCCGGCTG
A

Upstream 100 bases:

>100_bases
ACGACATGGCTGACCAGTGGACGAACGAATTGGCCCAGGCCCGCCTGCCCGACCTGGGGCTGCCGGCCGACCTGCTCGCC
TGCGCCTCCCGGTCAGCGCG

Downstream 100 bases:

>100_bases
CCCAGGGGCCTTCGACCTGACGACCTGGCGACCTGAAGACCTGAAGACCTGACGACGTGGAGACCTGATGACGATCGACG
GAAAAGACACCGCCGTGTTC

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III protein 3; Beta-ketoacyl-ACP synthase III 3; KAS III 3 [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MSAVPATPRGRAAVIAGVGGYVPPNVVTNDDLAARLDTSDEWIRSRTGIAARNVVSPGTATSDLAVEAGRRALESAGVAE
AGAVVLATTTPDRPCPATAPEVASRLGLGGAAAFDIASVCSGFLYALAVGAGLIATGVAERVLVVGADAFTTIIDPQDRG
TAVIFADGAGAVVLRAGEPTEAGVVGTVVLGSDGARSDLIEVPGGGSRHRSSHAATGDGADLGDPYFRMRGRETYRHAVE
RMTSASRQAAAAAGWDVSRDVDRFAAHQANARILAAVADRLGVRPQRRLSNIEQVGNTGAASVPLLLAEATAAGALTAGH
RLLLTAFGGGLAWGATALVWPDVKAG

Sequences:

>Translated_346_residues
MSAVPATPRGRAAVIAGVGGYVPPNVVTNDDLAARLDTSDEWIRSRTGIAARNVVSPGTATSDLAVEAGRRALESAGVAE
AGAVVLATTTPDRPCPATAPEVASRLGLGGAAAFDIASVCSGFLYALAVGAGLIATGVAERVLVVGADAFTTIIDPQDRG
TAVIFADGAGAVVLRAGEPTEAGVVGTVVLGSDGARSDLIEVPGGGSRHRSSHAATGDGADLGDPYFRMRGRETYRHAVE
RMTSASRQAAAAAGWDVSRDVDRFAAHQANARILAAVADRLGVRPQRRLSNIEQVGNTGAASVPLLLAEATAAGALTAGH
RLLLTAFGGGLAWGATALVWPDVKAG
>Mature_345_residues
SAVPATPRGRAAVIAGVGGYVPPNVVTNDDLAARLDTSDEWIRSRTGIAARNVVSPGTATSDLAVEAGRRALESAGVAEA
GAVVLATTTPDRPCPATAPEVASRLGLGGAAAFDIASVCSGFLYALAVGAGLIATGVAERVLVVGADAFTTIIDPQDRGT
AVIFADGAGAVVLRAGEPTEAGVVGTVVLGSDGARSDLIEVPGGGSRHRSSHAATGDGADLGDPYFRMRGRETYRHAVER
MTSASRQAAAAAGWDVSRDVDRFAAHQANARILAAVADRLGVRPQRRLSNIEQVGNTGAASVPLLLAEATAAGALTAGHR
LLLTAFGGGLAWGATALVWPDVKAG

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=327, Percent_Identity=39.4495412844037, Blast_Score=216, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34827; Mature: 34696

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVPATPRGRAAVIAGVGGYVPPNVVTNDDLAARLDTSDEWIRSRTGIAARNVVSPGTA
CCCCCCCCCCCEEEEECCCCCCCCCCEECCCHHEECCCCHHHHHHHCCCHHHCCCCCCCC
TSDLAVEAGRRALESAGVAEAGAVVLATTTPDRPCPATAPEVASRLGLGGAAAFDIASVC
CHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHH
SGFLYALAVGAGLIATGVAERVLVVGADAFTTIIDPQDRGTAVIFADGAGAVVLRAGEPT
HHHHHHHHHHHHHHHHHHHHEEEEEECCHHEEEECCCCCCCEEEEECCCCEEEEECCCCC
EAGVVGTVVLGSDGARSDLIEVPGGGSRHRSSHAATGDGADLGDPYFRMRGRETYRHAVE
CCCEEEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHH
RMTSASRQAAAAAGWDVSRDVDRFAAHQANARILAAVADRLGVRPQRRLSNIEQVGNTGA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
ASVPLLLAEATAAGALTAGHRLLLTAFGGGLAWGATALVWPDVKAG
CCCCEEEEHHHHHHHHHCCCEEEEEECCCCHHHCCEEEECCCCCCC
>Mature Secondary Structure 
SAVPATPRGRAAVIAGVGGYVPPNVVTNDDLAARLDTSDEWIRSRTGIAARNVVSPGTA
CCCCCCCCCCEEEEECCCCCCCCCCEECCCHHEECCCCHHHHHHHCCCHHHCCCCCCCC
TSDLAVEAGRRALESAGVAEAGAVVLATTTPDRPCPATAPEVASRLGLGGAAAFDIASVC
CHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHH
SGFLYALAVGAGLIATGVAERVLVVGADAFTTIIDPQDRGTAVIFADGAGAVVLRAGEPT
HHHHHHHHHHHHHHHHHHHHEEEEEECCHHEEEECCCCCCCEEEEECCCCEEEEECCCCC
EAGVVGTVVLGSDGARSDLIEVPGGGSRHRSSHAATGDGADLGDPYFRMRGRETYRHAVE
CCCEEEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHH
RMTSASRQAAAAAGWDVSRDVDRFAAHQANARILAAVADRLGVRPQRRLSNIEQVGNTGA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
ASVPLLLAEATAAGALTAGHRLLLTAFGGGLAWGATALVWPDVKAG
CCCCEEEEHHHHHHHHHCCCEEEEEECCCCHHHCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]