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The map label for this gene is yedX [H]

Identifier: 158317427

GI number: 158317427

Start: 6894871

End: 6895197

Strand: Reverse

Name: yedX [H]

Synonym: Franean1_5679

Alternate gene names: 158317427

Gene position: 6895197-6894871 (Counterclockwise)

Preceding gene: 158317428

Following gene: 158317422

Centisome position: 76.77

GC content: 71.56

Gene sequence:

>327_bases
GTGAGCTTGTCGACCCATGTGCTGGACACCGCCTCTGGGAAGCCAGCCGCCGGCGTGCCGGTGCGCCTTGAACGGGCCGC
GGTCACCCTCGACGGCGCGACCAAGGGCTGGCGCCCAGTCGCCCAGGCGGTGACCGATGACGACGGGCGCGTCGGCGACC
TGCCCGCGGACCGCGCCGGCGCCTGGCGCCTCGTGTTCGACACCACGGGGCATTCGGCCTTCTACCCCGAGGTGGCGATC
GTCTTCGTCATCCGGGAGCCGGCCGACCACCATCACGTGCCCCTTCTACTTGCGCCGTACGGCTACTCCACCTACCGCGG
CAGCTGA

Upstream 100 bases:

>100_bases
TCTGATCACCGGCGCCTGACACCTGGTTCCCGGGTCGTGGCGAAGCGACGAGTGGGTCGCCGGCGGGCACCCCGGCGGCG
AGCCGGGGAGGGCGACGCGA

Downstream 100 bases:

>100_bases
CCCGGCCCGGCCTGACCCGCCCGGTCCGGCGGGTCAGCGCGGGACCTGCGGAGGCCGGCCTCCGAGGCGGGCGACCGTCT
CCTCGTCCAGACCGGCGGCC

Product: transthyretin

Products: NA

Alternate protein names: HIU hydrolase; HIUHase; Transthyretin-like protein; TLP [H]

Number of amino acids: Translated: 108; Mature: 107

Protein sequence:

>108_residues
MSLSTHVLDTASGKPAAGVPVRLERAAVTLDGATKGWRPVAQAVTDDDGRVGDLPADRAGAWRLVFDTTGHSAFYPEVAI
VFVIREPADHHHVPLLLAPYGYSTYRGS

Sequences:

>Translated_108_residues
MSLSTHVLDTASGKPAAGVPVRLERAAVTLDGATKGWRPVAQAVTDDDGRVGDLPADRAGAWRLVFDTTGHSAFYPEVAI
VFVIREPADHHHVPLLLAPYGYSTYRGS
>Mature_107_residues
SLSTHVLDTASGKPAAGVPVRLERAAVTLDGATKGWRPVAQAVTDDDGRVGDLPADRAGAWRLVFDTTGHSAFYPEVAIV
FVIREPADHHHVPLLLAPYGYSTYRGS

Specific function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) [H]

COG id: COG2351

COG function: function code R; Transthyretin-like protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788281, Length=115, Percent_Identity=44.3478260869565, Blast_Score=90, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI115534555, Length=116, Percent_Identity=41.3793103448276, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115532920, Length=116, Percent_Identity=39.6551724137931, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115532922, Length=116, Percent_Identity=39.6551724137931, Blast_Score=79, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24652571, Length=118, Percent_Identity=38.135593220339, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014306
- InterPro:   IPR000895 [H]

Pfam domain/function: PF00576 Transthyretin [H]

EC number: =3.5.2.17 [H]

Molecular weight: Translated: 11538; Mature: 11407

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00768 TRANSTHYRETIN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSTHVLDTASGKPAAGVPVRLERAAVTLDGATKGWRPVAQAVTDDDGRVGDLPADRAG
CCCCCCEEECCCCCCCCCCCEEEEEEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCC
AWRLVFDTTGHSAFYPEVAIVFVIREPADHHHVPLLLAPYGYSTYRGS
CEEEEEECCCCCEECCCEEEEEEEECCCCCCCCCEEEECCCCCCCCCC
>Mature Secondary Structure 
SLSTHVLDTASGKPAAGVPVRLERAAVTLDGATKGWRPVAQAVTDDDGRVGDLPADRAG
CCCCCEEECCCCCCCCCCCEEEEEEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCC
AWRLVFDTTGHSAFYPEVAIVFVIREPADHHHVPLLLAPYGYSTYRGS
CEEEEEECCCCCEECCCEEEEEEEECCCCCCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]