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The map label for this gene is recQ [H]

Identifier: 158317217

GI number: 158317217

Start: 6607621

End: 6609438

Strand: Direct

Name: recQ [H]

Synonym: Franean1_5464

Alternate gene names: 158317217

Gene position: 6607621-6609438 (Clockwise)

Preceding gene: 158317216

Following gene: 158317219

Centisome position: 73.56

GC content: 71.12

Gene sequence:

>1818_bases
GTGGAAGTGCTCCGCCGCGTCTTCGGCTACGAGTCCTTCCGCGACGGCCAGCAGGAGATCATCGATCACGTCGTCGGCGG
TGGCGACGCGCTGGTCCTCATGCCGACCGGCGGCGGCAAGTCGCTGTGCTACCAGATCCCGGCGCTCGTCCGGCCTGGCA
CCGGCGTCGTCATCTCCCCGCTCATCGCGCTGATGCAGGACCAGGTCGACGCGTTGCTGGCGCTCGGGGTCCGGGCGGGG
TTCCTCAACTCCACCCAGCAGGCCGACGAGCGCCGCGCGGTGGAGTCCGCGTTCCTCGCCGGCGAGCTCGACCTGCTCTA
CCTGGCCCCCGAGCGGCTGCGGGTACGCGCGACGATCGAGCTCCTCGACCAGGGCGAGATCGCGCTGTTCGCGATCGACG
AGGCGCACTGCGTCGCGCAGTGGGGGCACGACTTCCGGCCCGACTACCTCCTGCTCTCCGAGCTGCACCAGCACTGGCCG
CAGGTGCCGCGCGTCGCACTGACCGCCACCGCCACCCCGGCGACCCACCAGGAGATCACGAACCGGCTCGGGCTGGGAAA
CGCCCGCCATTTCGTCGCCGACTTCGACCGGCCGAACATCCAGTACCGCATCGTGCCGAAGAACGACCCGAAGGCACAGC
TGCTGGAGCTCCTGCGCACCGAGCACCCCGGCGACGCGGGCATCGTGTACTGCCTGTCCCGGGCGTCGGTCGAGAAGATC
GCGGAGTTCCTGGTGTCGAACGGGATCGCCGCGCTGCCCTACCACGCCGGCCTCGAAGCACGCGTCCGCGCCGAGCACCA
AGCCCGTTTCCTCCGTGAGGACGGCCTGGTCATGGTCGCCACGATCGCCTTCGGGATGGGCATCGACAAGCCGGACGTCC
GCTTCGTCGCCCACCTCGACCTACCGAAGTCGGTAGAGGGCTATTACCAGGAGACCGGCCGCGCCGGCCGGGACGGGCTG
CGCTCCACCGCCTGGCTCGCGTACGGCCTGCAGGACGTGGTCCAGCAGCGCCGGCTCATCGACGCCTCCGACGGCGACGC
CACGCACCGCCGGCGGCTCAACTCCCACCTCGACGCGATGCTCGCACTGTGCGAGACCATCGAGTGCCGCCGGGTCGGCC
TGCTGGCGTACTTCGGGCAGCAGGGGTCGAGCGCCTGCGGCAACTGCGACGCCTGCCTGCACCCGCAGCAGTCCTGGGAG
GCGACCGTGCCCGCCCAGAAGCTGCTGTCGACGGTGCTGCGCCTGCAGCGGGAACGCCGGCAGAAGTTCGGCGCCGGCCA
CATCGTCGACATCCTGCTGGGCCGGCGCACACCCAAGGTCAACCAGCACGGCCACGACTCGCTGACGGTCTTCGGCATCG
GCACCGAGCTCAGCGAGGCCGAGTGGCGTGGCGTGGTCCGCCAGCTGCTGGCCCAGGGGCTGCTGGCCGTCGAGGGTGAG
CACGGAACGCTCGTCCTCACCGACGCGAGCGCGGACGTCCTGCGCGGGCAGCGGACGGTCTCCATGCGGCGCGAACCGAA
GCGACCGGCGAAGGCCACCAGCTCCTCGGCGACGAAGGCACGCCGGGCCGAGCCGGTCGAACTGTCCGCGGAGGCGGCGC
CGCTGTTCGAACGGCTGCGCGCCTGGCGGGGCGCCACCGCCAAGGAACAGGGCGTTCCCGCCTACGTGATCTTCCATGAC
GCGACGCTGCGCGAGATCGCCACCCGCGCGCCCTCCTCGCTCGCCGAGCTCGCGACGGTGAACGGCGTCGGCGAGAACAA
GCTGGCCAAGTACGGCGAACACATCCTCCCGCTGTGTAGCGCCACGCCCACGGACTGA

Upstream 100 bases:

>100_bases
ACGGGTTGTCCACAGGCGCGAACTCGCGTCACCCTCGTCCCGTGAGGCCTTCTACAGTGGCGCGGTGACCTCGCCCTCGG
TTCGCGTCCCGCGTGACGCC

Downstream 100 bases:

>100_bases
CCCACAACGGACCGGCCCACGGCGCGGCGCGGCCATCGCTGCGGCGGGAGAGCGGAGCGCGGCGACGCTCAGACGGGCTC
GTGCCGGCGGATCCGCTCGT

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MEVLRRVFGYESFRDGQQEIIDHVVGGGDALVLMPTGGGKSLCYQIPALVRPGTGVVISPLIALMQDQVDALLALGVRAG
FLNSTQQADERRAVESAFLAGELDLLYLAPERLRVRATIELLDQGEIALFAIDEAHCVAQWGHDFRPDYLLLSELHQHWP
QVPRVALTATATPATHQEITNRLGLGNARHFVADFDRPNIQYRIVPKNDPKAQLLELLRTEHPGDAGIVYCLSRASVEKI
AEFLVSNGIAALPYHAGLEARVRAEHQARFLREDGLVMVATIAFGMGIDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGL
RSTAWLAYGLQDVVQQRRLIDASDGDATHRRRLNSHLDAMLALCETIECRRVGLLAYFGQQGSSACGNCDACLHPQQSWE
ATVPAQKLLSTVLRLQRERRQKFGAGHIVDILLGRRTPKVNQHGHDSLTVFGIGTELSEAEWRGVVRQLLAQGLLAVEGE
HGTLVLTDASADVLRGQRTVSMRREPKRPAKATSSSATKARRAEPVELSAEAAPLFERLRAWRGATAKEQGVPAYVIFHD
ATLREIATRAPSSLAELATVNGVGENKLAKYGEHILPLCSATPTD

Sequences:

>Translated_605_residues
MEVLRRVFGYESFRDGQQEIIDHVVGGGDALVLMPTGGGKSLCYQIPALVRPGTGVVISPLIALMQDQVDALLALGVRAG
FLNSTQQADERRAVESAFLAGELDLLYLAPERLRVRATIELLDQGEIALFAIDEAHCVAQWGHDFRPDYLLLSELHQHWP
QVPRVALTATATPATHQEITNRLGLGNARHFVADFDRPNIQYRIVPKNDPKAQLLELLRTEHPGDAGIVYCLSRASVEKI
AEFLVSNGIAALPYHAGLEARVRAEHQARFLREDGLVMVATIAFGMGIDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGL
RSTAWLAYGLQDVVQQRRLIDASDGDATHRRRLNSHLDAMLALCETIECRRVGLLAYFGQQGSSACGNCDACLHPQQSWE
ATVPAQKLLSTVLRLQRERRQKFGAGHIVDILLGRRTPKVNQHGHDSLTVFGIGTELSEAEWRGVVRQLLAQGLLAVEGE
HGTLVLTDASADVLRGQRTVSMRREPKRPAKATSSSATKARRAEPVELSAEAAPLFERLRAWRGATAKEQGVPAYVIFHD
ATLREIATRAPSSLAELATVNGVGENKLAKYGEHILPLCSATPTD
>Mature_605_residues
MEVLRRVFGYESFRDGQQEIIDHVVGGGDALVLMPTGGGKSLCYQIPALVRPGTGVVISPLIALMQDQVDALLALGVRAG
FLNSTQQADERRAVESAFLAGELDLLYLAPERLRVRATIELLDQGEIALFAIDEAHCVAQWGHDFRPDYLLLSELHQHWP
QVPRVALTATATPATHQEITNRLGLGNARHFVADFDRPNIQYRIVPKNDPKAQLLELLRTEHPGDAGIVYCLSRASVEKI
AEFLVSNGIAALPYHAGLEARVRAEHQARFLREDGLVMVATIAFGMGIDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGL
RSTAWLAYGLQDVVQQRRLIDASDGDATHRRRLNSHLDAMLALCETIECRRVGLLAYFGQQGSSACGNCDACLHPQQSWE
ATVPAQKLLSTVLRLQRERRQKFGAGHIVDILLGRRTPKVNQHGHDSLTVFGIGTELSEAEWRGVVRQLLAQGLLAVEGE
HGTLVLTDASADVLRGQRTVSMRREPKRPAKATSSSATKARRAEPVELSAEAAPLFERLRAWRGATAKEQGVPAYVIFHD
ATLREIATRAPSSLAELATVNGVGENKLAKYGEHILPLCSATPTD

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=645, Percent_Identity=37.2093023255814, Blast_Score=382, Evalue=1e-106,
Organism=Homo sapiens, GI14591902, Length=454, Percent_Identity=35.0220264317181, Blast_Score=280, Evalue=4e-75,
Organism=Homo sapiens, GI14591904, Length=454, Percent_Identity=35.0220264317181, Blast_Score=280, Evalue=4e-75,
Organism=Homo sapiens, GI148612816, Length=422, Percent_Identity=40.2843601895735, Blast_Score=274, Evalue=1e-73,
Organism=Homo sapiens, GI169218196, Length=588, Percent_Identity=33.843537414966, Blast_Score=262, Evalue=6e-70,
Organism=Homo sapiens, GI110735439, Length=588, Percent_Identity=33.843537414966, Blast_Score=262, Evalue=6e-70,
Organism=Homo sapiens, GI51242943, Length=393, Percent_Identity=40.9669211195929, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI51242947, Length=395, Percent_Identity=40.5063291139241, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI284005309, Length=371, Percent_Identity=35.8490566037736, Blast_Score=184, Evalue=2e-46,
Organism=Escherichia coli, GI48994977, Length=605, Percent_Identity=45.2892561983471, Blast_Score=509, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI25145561, Length=652, Percent_Identity=34.5092024539877, Blast_Score=339, Evalue=2e-93,
Organism=Caenorhabditis elegans, GI71987997, Length=404, Percent_Identity=39.3564356435644, Blast_Score=292, Evalue=4e-79,
Organism=Caenorhabditis elegans, GI71987993, Length=404, Percent_Identity=39.3564356435644, Blast_Score=292, Evalue=4e-79,
Organism=Caenorhabditis elegans, GI32564293, Length=664, Percent_Identity=28.7650602409639, Blast_Score=259, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI17552866, Length=438, Percent_Identity=36.3013698630137, Blast_Score=254, Evalue=8e-68,
Organism=Caenorhabditis elegans, GI71987143, Length=344, Percent_Identity=23.8372093023256, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6323844, Length=493, Percent_Identity=37.9310344827586, Blast_Score=340, Evalue=4e-94,
Organism=Saccharomyces cerevisiae, GI6321360, Length=339, Percent_Identity=24.188790560472, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324778, Length=234, Percent_Identity=27.7777777777778, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24646066, Length=632, Percent_Identity=32.753164556962, Blast_Score=332, Evalue=6e-91,
Organism=Drosophila melanogaster, GI24664226, Length=435, Percent_Identity=39.0804597701149, Blast_Score=272, Evalue=4e-73,
Organism=Drosophila melanogaster, GI62472181, Length=435, Percent_Identity=39.0804597701149, Blast_Score=269, Evalue=5e-72,
Organism=Drosophila melanogaster, GI24664230, Length=435, Percent_Identity=39.0804597701149, Blast_Score=269, Evalue=5e-72,
Organism=Drosophila melanogaster, GI21358123, Length=378, Percent_Identity=37.8306878306878, Blast_Score=218, Evalue=9e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 66340; Mature: 66340

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVLRRVFGYESFRDGQQEIIDHVVGGGDALVLMPTGGGKSLCYQIPALVRPGTGVVISP
CHHHHHHHCCHHHCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHCCHHCCCCCCHHHHH
LIALMQDQVDALLALGVRAGFLNSTQQADERRAVESAFLAGELDLLYLAPERLRVRATIE
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHEEEEEEE
LLDQGEIALFAIDEAHCVAQWGHDFRPDYLLLSELHQHWPQVPRVALTATATPATHQEIT
ECCCCCEEEEEECCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHH
NRLGLGNARHFVADFDRPNIQYRIVPKNDPKAQLLELLRTEHPGDAGIVYCLSRASVEKI
HHHCCCCCHHHEEECCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEHHHHHHHH
AEFLVSNGIAALPYHAGLEARVRAEHQARFLREDGLVMVATIAFGMGIDKPDVRFVAHLD
HHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCCCEEEEEEC
LPKSVEGYYQETGRAGRDGLRSTAWLAYGLQDVVQQRRLIDASDGDATHRRRLNSHLDAM
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LALCETIECRRVGLLAYFGQQGSSACGNCDACLHPQQSWEATVPAQKLLSTVLRLQRERR
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
QKFGAGHIVDILLGRRTPKVNQHGHDSLTVFGIGTELSEAEWRGVVRQLLAQGLLAVEGE
HHCCCCHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEECC
HGTLVLTDASADVLRGQRTVSMRREPKRPAKATSSSATKARRAEPVELSAEAAPLFERLR
CCEEEEECCCHHHHCCCHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHH
AWRGATAKEQGVPAYVIFHDATLREIATRAPSSLAELATVNGVGENKLAKYGEHILPLCS
HHCCCCCCCCCCCEEEEEECHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
ATPTD
CCCCC
>Mature Secondary Structure
MEVLRRVFGYESFRDGQQEIIDHVVGGGDALVLMPTGGGKSLCYQIPALVRPGTGVVISP
CHHHHHHHCCHHHCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHCCHHCCCCCCHHHHH
LIALMQDQVDALLALGVRAGFLNSTQQADERRAVESAFLAGELDLLYLAPERLRVRATIE
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHEEEEEEE
LLDQGEIALFAIDEAHCVAQWGHDFRPDYLLLSELHQHWPQVPRVALTATATPATHQEIT
ECCCCCEEEEEECCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHH
NRLGLGNARHFVADFDRPNIQYRIVPKNDPKAQLLELLRTEHPGDAGIVYCLSRASVEKI
HHHCCCCCHHHEEECCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEHHHHHHHH
AEFLVSNGIAALPYHAGLEARVRAEHQARFLREDGLVMVATIAFGMGIDKPDVRFVAHLD
HHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCCCEEEEEEC
LPKSVEGYYQETGRAGRDGLRSTAWLAYGLQDVVQQRRLIDASDGDATHRRRLNSHLDAM
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LALCETIECRRVGLLAYFGQQGSSACGNCDACLHPQQSWEATVPAQKLLSTVLRLQRERR
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
QKFGAGHIVDILLGRRTPKVNQHGHDSLTVFGIGTELSEAEWRGVVRQLLAQGLLAVEGE
HHCCCCHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEECC
HGTLVLTDASADVLRGQRTVSMRREPKRPAKATSSSATKARRAEPVELSAEAAPLFERLR
CCEEEEECCCHHHHCCCHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHH
AWRGATAKEQGVPAYVIFHDATLREIATRAPSSLAELATVNGVGENKLAKYGEHILPLCS
HHCCCCCCCCCCCEEEEEECHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
ATPTD
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]