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The map label for this gene is celR [H]

Identifier: 158317216

GI number: 158317216

Start: 6606450

End: 6607484

Strand: Direct

Name: celR [H]

Synonym: Franean1_5463

Alternate gene names: 158317216

Gene position: 6606450-6607484 (Clockwise)

Preceding gene: 158317215

Following gene: 158317217

Centisome position: 73.55

GC content: 74.78

Gene sequence:

>1035_bases
GTGACGCCGGAGCCACCGGCCCGGACCCGCCAGGCGCCGACGCTGGAGGCCGTCGCCGAGCTGGCGGGGGTGTCGCGGGC
GACGGTCTCCCGGGTGGTGAACGGGTCGCTCCGCGTCTCCCCCGCGGCGCACGCCGCGGTCACCAGGGCGATCGCCGAGC
TCGGCTACGTGCCGAACCAGGCCGCCCGCAGCCTGGTGACCAGGCGGACGGACACGATCGTGCTGATCGTGCACGAGCGG
CCCGACACGGTGTTCGCCGACCCGTTCTTCGCCAGCGTGCTGCGCGGAGTGAACCAGGCGCTGAGCGTCACCCAGCTCCA
GCTCGTCCTGTTACAGGTGCAGGGTGACCGGCAGCGCGACCGGGCGCTGCGCTACGTCGGCAACGGCCACGTCGACGGAG
TGCTCCTGATCTCCCTGCACGGGGACGACATCATGCCGATGTCGGTCTCGGGCGCCGGGGTCCCACTGGTGATGGCGGGA
CGGCTACTCACCGGCGACCCGGTCGACTCGGTCGACGCCGACAACGTGGGCGGCGCCCGGCAGGCCGTGCGCCATCTCGT
CGCGACGGGCCGCCGCGAGTTGGCGACCGTCGCCGGGCCGGTGGACATGAGCGTGGGCGTCGACCGCCTGGCCGGCTACA
CGCAGGCGGCCCGCGACGCGAACCTGCCGGCCTCGGCCACCCGGGTCGAGACCGGCGACTTCACCGAGGCCAGCGGCCAG
GCGGCGGCGGCCCGGCTGCTGGCGGAGCACCCGACGATCGACGCGGTGTTCGCAGCCTCCGACCTGATGGCCCTCGGCGT
GCTGCGCGCGCTGCGGGCCGCCGGGCGGCGGGTTCCCGACGACGTCGCCGTCGTCGGCTTCGACGACGCGGCGCCGGCGG
TCTACGCGGACCCGCCGCTGACGACCGTCCGCCAGCCGGTGGAGCGGCTCGGCGCGGAGATGGTGCACCAGCTCCTGCGG
CGCATCGCCGATCCCACCGGCGACACGGCGTCGGTGATCCTGCCGACGGAGCTGGTGATCCGTTCGTCAGCCTGA

Upstream 100 bases:

>100_bases
TCGTGCACGTCGACTTCGAGTCCCTGGTGCGCACGCCGAAGTCCAGCGGGCTGTGGTACTCGCGGCTGATCCGGGAGCAC
CGCGCGGCAAGCGGGACGCG

Downstream 100 bases:

>100_bases
GCCGGTTCCCCGCTGGGGACAACGGGCGGGTCGGGAACGGGTTGTCCACAGGCGCGAACTCGCGTCACCCTCGTCCCGTG
AGGCCTTCTACAGTGGCGCG

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTPEPPARTRQAPTLEAVAELAGVSRATVSRVVNGSLRVSPAAHAAVTRAIAELGYVPNQAARSLVTRRTDTIVLIVHER
PDTVFADPFFASVLRGVNQALSVTQLQLVLLQVQGDRQRDRALRYVGNGHVDGVLLISLHGDDIMPMSVSGAGVPLVMAG
RLLTGDPVDSVDADNVGGARQAVRHLVATGRRELATVAGPVDMSVGVDRLAGYTQAARDANLPASATRVETGDFTEASGQ
AAAARLLAEHPTIDAVFAASDLMALGVLRALRAAGRRVPDDVAVVGFDDAAPAVYADPPLTTVRQPVERLGAEMVHQLLR
RIADPTGDTASVILPTELVIRSSA

Sequences:

>Translated_344_residues
MTPEPPARTRQAPTLEAVAELAGVSRATVSRVVNGSLRVSPAAHAAVTRAIAELGYVPNQAARSLVTRRTDTIVLIVHER
PDTVFADPFFASVLRGVNQALSVTQLQLVLLQVQGDRQRDRALRYVGNGHVDGVLLISLHGDDIMPMSVSGAGVPLVMAG
RLLTGDPVDSVDADNVGGARQAVRHLVATGRRELATVAGPVDMSVGVDRLAGYTQAARDANLPASATRVETGDFTEASGQ
AAAARLLAEHPTIDAVFAASDLMALGVLRALRAAGRRVPDDVAVVGFDDAAPAVYADPPLTTVRQPVERLGAEMVHQLLR
RIADPTGDTASVILPTELVIRSSA
>Mature_343_residues
TPEPPARTRQAPTLEAVAELAGVSRATVSRVVNGSLRVSPAAHAAVTRAIAELGYVPNQAARSLVTRRTDTIVLIVHERP
DTVFADPFFASVLRGVNQALSVTQLQLVLLQVQGDRQRDRALRYVGNGHVDGVLLISLHGDDIMPMSVSGAGVPLVMAGR
LLTGDPVDSVDADNVGGARQAVRHLVATGRRELATVAGPVDMSVGVDRLAGYTQAARDANLPASATRVETGDFTEASGQA
AAARLLAEHPTIDAVFAASDLMALGVLRALRAAGRRVPDDVAVVGFDDAAPAVYADPPLTTVRQPVERLGAEMVHQLLRR
IADPTGDTASVILPTELVIRSSA

Specific function: Binds to the 14-bp operator sequence 5'-TGGGAGCGCTCCCA- 3' in the upstream regions of cellulase genes; these operator sequences are modulated by cellobiose [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=337, Percent_Identity=36.4985163204748, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1790369, Length=344, Percent_Identity=32.5581395348837, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1787948, Length=333, Percent_Identity=31.8318318318318, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1787580, Length=316, Percent_Identity=29.746835443038, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789068, Length=312, Percent_Identity=31.4102564102564, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1789202, Length=295, Percent_Identity=31.864406779661, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788474, Length=310, Percent_Identity=30.9677419354839, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1787906, Length=346, Percent_Identity=30.635838150289, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1786540, Length=349, Percent_Identity=31.2320916905444, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI48994940, Length=318, Percent_Identity=29.2452830188679, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1789456, Length=347, Percent_Identity=23.6311239193084, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790192, Length=262, Percent_Identity=32.0610687022901, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790715, Length=328, Percent_Identity=23.4756097560976, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36058; Mature: 35926

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPEPPARTRQAPTLEAVAELAGVSRATVSRVVNGSLRVSPAAHAAVTRAIAELGYVPNQ
CCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCEEECHHHHHHHHHHHHHHCCCCCH
AARSLVTRRTDTIVLIVHERPDTVFADPFFASVLRGVNQALSVTQLQLVLLQVQGDRQRD
HHHHHHHHCCCEEEEEEECCCCCEECCHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHH
RALRYVGNGHVDGVLLISLHGDDIMPMSVSGAGVPLVMAGRLLTGDPVDSVDADNVGGAR
HHHHHHCCCCCCEEEEEEECCCCCCEEECCCCCCCHHEECEEECCCCCCCCCCCCCCHHH
QAVRHLVATGRRELATVAGPVDMSVGVDRLAGYTQAARDANLPASATRVETGDFTEASGQ
HHHHHHHHCCCHHHHHHCCCCCHHCCHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCH
AAAARLLAEHPTIDAVFAASDLMALGVLRALRAAGRRVPDDVAVVGFDDAAPAVYADPPL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEECCCCH
TTVRQPVERLGAEMVHQLLRRIADPTGDTASVILPTELVIRSSA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHEEEECCC
>Mature Secondary Structure 
TPEPPARTRQAPTLEAVAELAGVSRATVSRVVNGSLRVSPAAHAAVTRAIAELGYVPNQ
CCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCEEECHHHHHHHHHHHHHHCCCCCH
AARSLVTRRTDTIVLIVHERPDTVFADPFFASVLRGVNQALSVTQLQLVLLQVQGDRQRD
HHHHHHHHCCCEEEEEEECCCCCEECCHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHH
RALRYVGNGHVDGVLLISLHGDDIMPMSVSGAGVPLVMAGRLLTGDPVDSVDADNVGGAR
HHHHHHCCCCCCEEEEEEECCCCCCEEECCCCCCCHHEECEEECCCCCCCCCCCCCCHHH
QAVRHLVATGRRELATVAGPVDMSVGVDRLAGYTQAARDANLPASATRVETGDFTEASGQ
HHHHHHHHCCCHHHHHHCCCCCHHCCHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCH
AAAARLLAEHPTIDAVFAASDLMALGVLRALRAAGRRVPDDVAVVGFDDAAPAVYADPPL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEECCCCH
TTVRQPVERLGAEMVHQLLRRIADPTGDTASVILPTELVIRSSA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10224066 [H]