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The map label for this gene is map [H]

Identifier: 158317153

GI number: 158317153

Start: 6515199

End: 6516977

Strand: Reverse

Name: map [H]

Synonym: Franean1_5400

Alternate gene names: 158317153

Gene position: 6516977-6515199 (Counterclockwise)

Preceding gene: 158317154

Following gene: 158317152

Centisome position: 72.56

GC content: 68.75

Gene sequence:

>1779_bases
GTGTCCGGATTCGAGCTGCCGCGCAACCTCTCATGTGCCGGGGCGGGGCGCCGCCGATCGCCCGGTCGTGCTGAAGGTCG
GCTGGCGCCGCAGGGAAGCGAACACGAGACCGATGGTCTGCGGACCTGGGCCGGGCGGGGAGCGGTGTTCCTCCTCGACG
CCCTAGCTAGCCGACGGGGCGACCAGCGCGCTGCCGCTCGAACGCTGGGAGCCGGGCACGACTCTCGCCGGGGCACGAGC
GGAACACGAGCAGGACGCGGTCGTCGCCGGACTGCTGCGCCGACTGTGGATCACCCCGTCAGACGGGCTCCGTTCCGCCC
GCTGCAAGACATGTGCGACGCCTGGGCAGCCGAGTTCGCCGAACGACTCGACGCCGCGCCCGGCGCGATCGACCCAGGGC
TGGCCCGCGCCGCCATCGAGTTGTTCCACACGCTGCCGGGCAGCGTCGAGCGGGAAGTGCTGCTGTGCACTGACCCGCAC
GCCGGGAACATCCTGGCGGCCCGGCGCGAGCCGTGGCTGGTCATCGACCCGAAACCCTACGTCGGCGATCCCGCCTACGA
CCCGGTCCAGCACATGCTCAACCGAGACGAGGGCCTCGACCTCGACCCCGACCGGGTCAACCGGTGGCTGTTCGCCCGCT
GCGCCCAGCAATCGATCGACGTTGCAGGTCGCCTCGGCCCGGGAGCACGGCTGGACATGGGAACGGATCGCCGCCGCGAT
GGGGAGCACCCGGGCGGTACACAAGAAGTACGTAGCGAGCAGGCGGATCGGACGGAGGCAGCCATGAGCCGGCGTAAGGC
CCACGGCTGCGACGGGCCCACGGCCCACCTGTCTCGGCCGATCAGCCCGGTGCTGACGGCGGCCCGGGAGGAGGCCGAGC
AGGCCCGCCACGGCTATGTCGGGCCCGAGACTCACGAGGCCAACCGCTCGCGTGCGTTGCGACCTGATCTTGTGGGTTCG
ACCTCGCCGTCAGGCTGGTTGATCTCGGCCCACACTTCATCGAGGGAGAGCCCGAGGACATCGGCGATCGCCGCGATGGT
CGGGAAGGCAGGGGTGGCTACGCGACCAGACTCGATCTTCCGAAGGGTTTCTGGTGAGACACCTGCATCTAGCGCGGTTC
GGTGGACCAAGACCATGATCGTCGAGGCTGGGGCGCAGTCCTGCTACGTCGACTATGAGCCGTCCTTCGGACGCGGGCCG
TTCGGCCACTACATCTGCACGGCCGTCAACGACGCCGTGCTCCACGGACTGCCCTACGACTACACGCTTGCCGACGGCGA
CCTGCTGACGCTCGACCTCGCCGTCTCCAGAGACGGAGTCGCTGCAGACTCCGCCATCAGCTTCATCGTGGGCGACTCAA
AGCCCCCGGAGAGCGTCGCGATGATCAGCGCAACCGAACGCGCATTGAGCGCAGGGATAGCCGCTGCCGGCCCCGGAGCT
CGCATCGGCGACATCTCCCATGCCATCGGCTCCGTCCTCAGCGAGGCAGGGTACCCGATCAACACCGAGTTCGGAGGTCA
TGGCATCGGATCAACGATGCACCAGGACCCGCACGTTTCAAACACCGGACGGCCCGGCCGTGGATACAGACTGCGCCCTG
GGCTGCTGCTCGCGCTGGAGCCGTGGGTCATGGCGGACACCGCCGAGCTCGTCACCGATGCCGACGGCTGGACCCTCCGA
AGCGCGACAGGCTGCCGGACAGCGCACAGTGAGCACACGATCGCCATCATCAACAACGGAGCCGAAATCCTCACCTTGCC
GACGCAGGCGCACTCGTGA

Upstream 100 bases:

>100_bases
AGCGCCGCCCGTAGCCCGTTCACGCCGGCGTGCTGGCACCGGTGCCGGGATTACCGCCTGGCGTCCGGTGCCGGCTACGG
ACGTGGGCGAGGATGCCCGT

Downstream 100 bases:

>100_bases
GATCGGAGCCACACCCGGTCCATGACGTACCCGCACGGAGACGGCATCGCGTTCGGCGCCGATCTCCGGCATCAGATTTA
CCACCTGTGGGCAACGCATG

Product: methionyl aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 592; Mature: 591

Protein sequence:

>592_residues
MSGFELPRNLSCAGAGRRRSPGRAEGRLAPQGSEHETDGLRTWAGRGAVFLLDALASRRGDQRAAARTLGAGHDSRRGTS
GTRAGRGRRRTAAPTVDHPVRRAPFRPLQDMCDAWAAEFAERLDAAPGAIDPGLARAAIELFHTLPGSVEREVLLCTDPH
AGNILAARREPWLVIDPKPYVGDPAYDPVQHMLNRDEGLDLDPDRVNRWLFARCAQQSIDVAGRLGPGARLDMGTDRRRD
GEHPGGTQEVRSEQADRTEAAMSRRKAHGCDGPTAHLSRPISPVLTAAREEAEQARHGYVGPETHEANRSRALRPDLVGS
TSPSGWLISAHTSSRESPRTSAIAAMVGKAGVATRPDSIFRRVSGETPASSAVRWTKTMIVEAGAQSCYVDYEPSFGRGP
FGHYICTAVNDAVLHGLPYDYTLADGDLLTLDLAVSRDGVAADSAISFIVGDSKPPESVAMISATERALSAGIAAAGPGA
RIGDISHAIGSVLSEAGYPINTEFGGHGIGSTMHQDPHVSNTGRPGRGYRLRPGLLLALEPWVMADTAELVTDADGWTLR
SATGCRTAHSEHTIAIINNGAEILTLPTQAHS

Sequences:

>Translated_592_residues
MSGFELPRNLSCAGAGRRRSPGRAEGRLAPQGSEHETDGLRTWAGRGAVFLLDALASRRGDQRAAARTLGAGHDSRRGTS
GTRAGRGRRRTAAPTVDHPVRRAPFRPLQDMCDAWAAEFAERLDAAPGAIDPGLARAAIELFHTLPGSVEREVLLCTDPH
AGNILAARREPWLVIDPKPYVGDPAYDPVQHMLNRDEGLDLDPDRVNRWLFARCAQQSIDVAGRLGPGARLDMGTDRRRD
GEHPGGTQEVRSEQADRTEAAMSRRKAHGCDGPTAHLSRPISPVLTAAREEAEQARHGYVGPETHEANRSRALRPDLVGS
TSPSGWLISAHTSSRESPRTSAIAAMVGKAGVATRPDSIFRRVSGETPASSAVRWTKTMIVEAGAQSCYVDYEPSFGRGP
FGHYICTAVNDAVLHGLPYDYTLADGDLLTLDLAVSRDGVAADSAISFIVGDSKPPESVAMISATERALSAGIAAAGPGA
RIGDISHAIGSVLSEAGYPINTEFGGHGIGSTMHQDPHVSNTGRPGRGYRLRPGLLLALEPWVMADTAELVTDADGWTLR
SATGCRTAHSEHTIAIINNGAEILTLPTQAHS
>Mature_591_residues
SGFELPRNLSCAGAGRRRSPGRAEGRLAPQGSEHETDGLRTWAGRGAVFLLDALASRRGDQRAAARTLGAGHDSRRGTSG
TRAGRGRRRTAAPTVDHPVRRAPFRPLQDMCDAWAAEFAERLDAAPGAIDPGLARAAIELFHTLPGSVEREVLLCTDPHA
GNILAARREPWLVIDPKPYVGDPAYDPVQHMLNRDEGLDLDPDRVNRWLFARCAQQSIDVAGRLGPGARLDMGTDRRRDG
EHPGGTQEVRSEQADRTEAAMSRRKAHGCDGPTAHLSRPISPVLTAAREEAEQARHGYVGPETHEANRSRALRPDLVGST
SPSGWLISAHTSSRESPRTSAIAAMVGKAGVATRPDSIFRRVSGETPASSAVRWTKTMIVEAGAQSCYVDYEPSFGRGPF
GHYICTAVNDAVLHGLPYDYTLADGDLLTLDLAVSRDGVAADSAISFIVGDSKPPESVAMISATERALSAGIAAAGPGAR
IGDISHAIGSVLSEAGYPINTEFGGHGIGSTMHQDPHVSNTGRPGRGYRLRPGLLLALEPWVMADTAELVTDADGWTLRS
ATGCRTAHSEHTIAIINNGAEILTLPTQAHS

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI40385867, Length=204, Percent_Identity=31.3725490196078, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI164420681, Length=206, Percent_Identity=28.6407766990291, Blast_Score=97, Evalue=5e-20,
Organism=Escherichia coli, GI1786364, Length=186, Percent_Identity=35.4838709677419, Blast_Score=121, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71996291, Length=191, Percent_Identity=30.3664921465969, Blast_Score=103, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6323273, Length=191, Percent_Identity=26.7015706806283, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24583427, Length=185, Percent_Identity=35.1351351351351, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI21355531, Length=191, Percent_Identity=29.8429319371728, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 63016; Mature: 62885

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGFELPRNLSCAGAGRRRSPGRAEGRLAPQGSEHETDGLRTWAGRGAVFLLDALASRRG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCC
DQRAAARTLGAGHDSRRGTSGTRAGRGRRRTAAPTVDHPVRRAPFRPLQDMCDAWAAEFA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHH
ERLDAAPGAIDPGLARAAIELFHTLPGSVEREVLLCTDPHAGNILAARREPWLVIDPKPY
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEECCCCEEEECCCCC
VGDPAYDPVQHMLNRDEGLDLDPDRVNRWLFARCAQQSIDVAGRLGPGARLDMGTDRRRD
CCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCC
GEHPGGTQEVRSEQADRTEAAMSRRKAHGCDGPTAHLSRPISPVLTAAREEAEQARHGYV
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCC
GPETHEANRSRALRPDLVGSTSPSGWLISAHTSSRESPRTSAIAAMVGKAGVATRPDSIF
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCHHHH
RRVSGETPASSAVRWTKTMIVEAGAQSCYVDYEPSFGRGPFGHYICTAVNDAVLHGLPYD
HHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCC
YTLADGDLLTLDLAVSRDGVAADSAISFIVGDSKPPESVAMISATERALSAGIAAAGPGA
EEECCCCEEEEEEEECCCCCCCCCEEEEEECCCCCCCCEEEHHHHHHHHHHCCCCCCCCC
RIGDISHAIGSVLSEAGYPINTEFGGHGIGSTMHQDPHVSNTGRPGRGYRLRPGLLLALE
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEEEC
PWVMADTAELVTDADGWTLRSATGCRTAHSEHTIAIINNGAEILTLPTQAHS
CCHHCCHHHHHCCCCCCEEECCCCCCCCCCCCEEEEEECCCEEEEECCCCCC
>Mature Secondary Structure 
SGFELPRNLSCAGAGRRRSPGRAEGRLAPQGSEHETDGLRTWAGRGAVFLLDALASRRG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCC
DQRAAARTLGAGHDSRRGTSGTRAGRGRRRTAAPTVDHPVRRAPFRPLQDMCDAWAAEFA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHH
ERLDAAPGAIDPGLARAAIELFHTLPGSVEREVLLCTDPHAGNILAARREPWLVIDPKPY
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEECCCCEEEECCCCC
VGDPAYDPVQHMLNRDEGLDLDPDRVNRWLFARCAQQSIDVAGRLGPGARLDMGTDRRRD
CCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCC
GEHPGGTQEVRSEQADRTEAAMSRRKAHGCDGPTAHLSRPISPVLTAAREEAEQARHGYV
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCC
GPETHEANRSRALRPDLVGSTSPSGWLISAHTSSRESPRTSAIAAMVGKAGVATRPDSIF
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCHHHH
RRVSGETPASSAVRWTKTMIVEAGAQSCYVDYEPSFGRGPFGHYICTAVNDAVLHGLPYD
HHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCC
YTLADGDLLTLDLAVSRDGVAADSAISFIVGDSKPPESVAMISATERALSAGIAAAGPGA
EEECCCCEEEEEEEECCCCCCCCCEEEEEECCCCCCCCEEEHHHHHHHHHHCCCCCCCCC
RIGDISHAIGSVLSEAGYPINTEFGGHGIGSTMHQDPHVSNTGRPGRGYRLRPGLLLALE
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEEEC
PWVMADTAELVTDADGWTLRSATGCRTAHSEHTIAIINNGAEILTLPTQAHS
CCHHCCHHHHHCCCCCCEEECCCCCCCCCCCCEEEEEECCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192928; 11058132 [H]