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The map label for this gene is tig

Identifier: 158317031

GI number: 158317031

Start: 6344915

End: 6346438

Strand: Reverse

Name: tig

Synonym: Franean1_5275

Alternate gene names: 158317031

Gene position: 6346438-6344915 (Counterclockwise)

Preceding gene: 158317032

Following gene: 158317030

Centisome position: 70.66

GC content: 69.69

Gene sequence:

>1524_bases
GTGAAGGCCACCAAGGAGACCCTCAGCCCGACCCGGGTCAAGCTCACCGTCGAGGTGCCCTTCGACGAGCTCAAGCCGTC
CGTCGATGCCACCTACCGCAAGCTGGCGCGCCAGGTGCGCGTCTCCGGATTCCGCCCGGGCAAGGTCCCGCCGCGGATTC
TGGACCAGCGCCTGGGGCGCGGTGTGATCCTCGACGAGGCGATCCAGGAGGCGCTGCCGCGCCTTTACTCGGAGGCCGTC
CAGGCCGAAGAGGTGGACGTCCTGTCGCGTCCCGAGGTGGACATCACCGAGTTCGCCGATGGCGCGCAGCTGGTCTTCAC
GGCCGAGATGGATGTGCGCCCGGAGGTGACCCTGCCGGAGTTCGGCGAGCTGGAGCTCGTCGTCGAGCCGGCGACGGTGA
CCGATGAGCAGGTCGAGGAGCATCTGACGAACCTGCGTGACCGGTTCGCCGTGTTGAAGCCGGTCGAGCGCCCGGTCCAG
GAGGGCGACTTCGTCTCGCTGGACCTGTCGGCGTCGGTCGACGGTGAGGCGATCGAGGACGCGACCGCGACCGGGATGTC
GTACGAGGTCGGCAGCGGGAACCTGATCGACGGGATCGACGAGGCCATCGCCGGCGCGTCGGACGGCGATGAGCGCACGT
TCGACACCGAGCTGCTCGCCGGTGAGTACACGGGCCGCACGGCGCAGGTCACCGCTGTGGTGCGGGGCGTGAAGGAGAAG
GAGCTCCCGGAGCTCGACGACGACTTCGCGACGACGGCCAGCGAGTTCGACACGCTGGAGGAGCTGCGCGCCGACGTCCG
GACCAGGCTTGAGTCGAACCGGAAGGTCGAGCAGCTGGGCGAGGCCCGCGACAAGATGCTCGACAAGCTGATCGAGTTGG
TCGAGGTGCCGGTGCCGGATTCGGTGTTGGCCGGTGAGCTGGAGGCCCGTGAGCACCGTCTCGGGCACGAGCTGGAGCAC
ATCGGTACGGACCGGGCGACCTACCTGGAGACGCTGGGTCAGTCGGCGGAGGAGTTCGACGCGGAGGTCCGCAGCTCGGC
GGGCAAGGCGATCCGCTCGCAGTTCATCCTGGACGCGGTGATCGACGCCGAGTCGATCGGCCTTGACCAGGGTGAGCTGA
TGGAGCAGATCCTGATGCGCGCGCAGCGGGCCGGTGTGCAGCCTGACCAGTACGCCCAGCAGCTCGCGCAGGGCGAGGGG
CTGACCGCCCTGATGGCGGATGTCCTCCGCACGAAGGCGCTCTTCCTGCTGCTGGAGAACGCGAAGGTCGTCGACACCGA
GGGTAACGCGGTGGAGTTGAACCTGCCGCGCCGTCCGTCGGGCGAGGCCGAGGATGACGTCCGGGACATCTCGGACGAGC
TGGACGCCGAGGAGCTCGAGGTCCCGGCGGCGGCTCCCTCGGCGGAGGTCACCGCCGCGGCCGGCGACGAGGCCACCGCC
ACCGCCACCGCTACGGACGCGGACACCGCTACGGACGCGGACGGCGCGGGCGACTCCGAGCTGCCCGCGTCCGAGACCAA
GTAA

Upstream 100 bases:

>100_bases
TGCTTTGGGTGCAGGAGATCGGGAGTTCGAGTCTCCCCGCCCCGACCGATACCCTCGGCGCGTCACCCCGTCCAACGTCG
TACCAGGAGACCGCCGCGCC

Downstream 100 bases:

>100_bases
CGACCGCCAGGTAGCGACCTCCAGGTAACGACCGCCGAGCAGCGGCCGCCCCTGTGACGACGCCGCCCTGCGCCACGGGC
GCCGGGCGGCGGCCGTGGGG

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MKATKETLSPTRVKLTVEVPFDELKPSVDATYRKLARQVRVSGFRPGKVPPRILDQRLGRGVILDEAIQEALPRLYSEAV
QAEEVDVLSRPEVDITEFADGAQLVFTAEMDVRPEVTLPEFGELELVVEPATVTDEQVEEHLTNLRDRFAVLKPVERPVQ
EGDFVSLDLSASVDGEAIEDATATGMSYEVGSGNLIDGIDEAIAGASDGDERTFDTELLAGEYTGRTAQVTAVVRGVKEK
ELPELDDDFATTASEFDTLEELRADVRTRLESNRKVEQLGEARDKMLDKLIELVEVPVPDSVLAGELEAREHRLGHELEH
IGTDRATYLETLGQSAEEFDAEVRSSAGKAIRSQFILDAVIDAESIGLDQGELMEQILMRAQRAGVQPDQYAQQLAQGEG
LTALMADVLRTKALFLLLENAKVVDTEGNAVELNLPRRPSGEAEDDVRDISDELDAEELEVPAAAPSAEVTAAAGDEATA
TATATDADTATDADGAGDSELPASETK

Sequences:

>Translated_507_residues
MKATKETLSPTRVKLTVEVPFDELKPSVDATYRKLARQVRVSGFRPGKVPPRILDQRLGRGVILDEAIQEALPRLYSEAV
QAEEVDVLSRPEVDITEFADGAQLVFTAEMDVRPEVTLPEFGELELVVEPATVTDEQVEEHLTNLRDRFAVLKPVERPVQ
EGDFVSLDLSASVDGEAIEDATATGMSYEVGSGNLIDGIDEAIAGASDGDERTFDTELLAGEYTGRTAQVTAVVRGVKEK
ELPELDDDFATTASEFDTLEELRADVRTRLESNRKVEQLGEARDKMLDKLIELVEVPVPDSVLAGELEAREHRLGHELEH
IGTDRATYLETLGQSAEEFDAEVRSSAGKAIRSQFILDAVIDAESIGLDQGELMEQILMRAQRAGVQPDQYAQQLAQGEG
LTALMADVLRTKALFLLLENAKVVDTEGNAVELNLPRRPSGEAEDDVRDISDELDAEELEVPAAAPSAEVTAAAGDEATA
TATATDADTATDADGAGDSELPASETK
>Mature_507_residues
MKATKETLSPTRVKLTVEVPFDELKPSVDATYRKLARQVRVSGFRPGKVPPRILDQRLGRGVILDEAIQEALPRLYSEAV
QAEEVDVLSRPEVDITEFADGAQLVFTAEMDVRPEVTLPEFGELELVVEPATVTDEQVEEHLTNLRDRFAVLKPVERPVQ
EGDFVSLDLSASVDGEAIEDATATGMSYEVGSGNLIDGIDEAIAGASDGDERTFDTELLAGEYTGRTAQVTAVVRGVKEK
ELPELDDDFATTASEFDTLEELRADVRTRLESNRKVEQLGEARDKMLDKLIELVEVPVPDSVLAGELEAREHRLGHELEH
IGTDRATYLETLGQSAEEFDAEVRSSAGKAIRSQFILDAVIDAESIGLDQGELMEQILMRAQRAGVQPDQYAQQLAQGEG
LTALMADVLRTKALFLLLENAKVVDTEGNAVELNLPRRPSGEAEDDVRDISDELDAEELEVPAAAPSAEVTAAAGDEATA
TATATDADTATDADGAGDSELPASETK

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=313, Percent_Identity=28.7539936102236, Blast_Score=123, Evalue=2e-29,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_FRASN (A8L1X3)

Other databases:

- EMBL:   CP000820
- RefSeq:   YP_001509539.1
- ProteinModelPortal:   A8L1X3
- GeneID:   5673609
- GenomeReviews:   CP000820_GR
- KEGG:   fre:Franean1_5275
- HOGENOM:   HBG635105
- OMA:   ETAINDG
- ProtClustDB:   PRK01490
- BioCyc:   FSP1855:FRANEAN1_5275-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 54926; Mature: 54926

Theoretical pI: Translated: 3.98; Mature: 3.98

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKATKETLSPTRVKLTVEVPFDELKPSVDATYRKLARQVRVSGFRPGKVPPRILDQRLGR
CCCCCHHCCCEEEEEEEECCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
GVILDEAIQEALPRLYSEAVQAEEVDVLSRPEVDITEFADGAQLVFTAEMDVRPEVTLPE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEEECCCCCCCCCCCC
FGELELVVEPATVTDEQVEEHLTNLRDRFAVLKPVERPVQEGDFVSLDLSASVDGEAIED
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHH
ATATGMSYEVGSGNLIDGIDEAIAGASDGDERTFDTELLAGEYTGRTAQVTAVVRGVKEK
HHHCCCEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCHHH
ELPELDDDFATTASEFDTLEELRADVRTRLESNRKVEQLGEARDKMLDKLIELVEVPVPD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
SVLAGELEAREHRLGHELEHIGTDRATYLETLGQSAEEFDAEVRSSAGKAIRSQFILDAV
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IDAESIGLDQGELMEQILMRAQRAGVQPDQYAQQLAQGEGLTALMADVLRTKALFLLLEN
HHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECC
AKVVDTEGNAVELNLPRRPSGEAEDDVRDISDELDAEELEVPAAAPSAEVTAAAGDEATA
CEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHCCHHHHCCCCCCCCCCEEECCCCCCCC
TATATDADTATDADGAGDSELPASETK
EEECCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKATKETLSPTRVKLTVEVPFDELKPSVDATYRKLARQVRVSGFRPGKVPPRILDQRLGR
CCCCCHHCCCEEEEEEEECCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
GVILDEAIQEALPRLYSEAVQAEEVDVLSRPEVDITEFADGAQLVFTAEMDVRPEVTLPE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEEECCCCCCCCCCCC
FGELELVVEPATVTDEQVEEHLTNLRDRFAVLKPVERPVQEGDFVSLDLSASVDGEAIED
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHH
ATATGMSYEVGSGNLIDGIDEAIAGASDGDERTFDTELLAGEYTGRTAQVTAVVRGVKEK
HHHCCCEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCHHH
ELPELDDDFATTASEFDTLEELRADVRTRLESNRKVEQLGEARDKMLDKLIELVEVPVPD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
SVLAGELEAREHRLGHELEHIGTDRATYLETLGQSAEEFDAEVRSSAGKAIRSQFILDAV
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IDAESIGLDQGELMEQILMRAQRAGVQPDQYAQQLAQGEGLTALMADVLRTKALFLLLEN
HHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECC
AKVVDTEGNAVELNLPRRPSGEAEDDVRDISDELDAEELEVPAAAPSAEVTAAAGDEATA
CEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHCCHHHHCCCCCCCCCCEEECCCCCCCC
TATATDADTATDADGAGDSELPASETK
EEECCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA