Click here to switch to the map view.

The map label for this gene is obgE

Identifier: 158317014

GI number: 158317014

Start: 6321096

End: 6322721

Strand: Reverse

Name: obgE

Synonym: Franean1_5258

Alternate gene names: 158317014

Gene position: 6322721-6321096 (Counterclockwise)

Preceding gene: 158317015

Following gene: 158317013

Centisome position: 70.39

GC content: 74.17

Gene sequence:

>1626_bases
ATGCCGACGTTCGTCGACCGGGTGGTTCTGCACGCCGCCGCCGGCGACGGCGGGCACGGCTGCTGCTCGATCCACCGTGA
GAAGTTCAAACCGCTGGGCGGGCCGGACGGCGGTAACGGCGGCCGCGGCGGCAACGTGCTGCTGCGCGTCGACAGCGGCG
TGACGACCCTGCTCGACTTCCACTTCCACCCGCATCAGCGGGCCGGCGGCGGCCGTCCGGGCCAGGGCTCCAACCGCCAC
GGCGCGGACGGCGACGACCTGGTTCTGTCGGTGCCGGACGGTACCGTCGTGCTCTCGCCCGACGGCGAGCAGATCGTCGA
CCTGGTCGGGGCGGGGAGCACCTACGTCCTGGCGCACGGCGGCCGCGGGGGGCGGGGTAACGCCTCGCTGGCCTCGGCCC
GCCGCAAGGCGCCCGGCTTCGCCGAGCTTGGGGAGCCGGGTGAGCAGCTCGACGCCGTCCTCGAGCTCAAGAGCGTGGCC
GACGTCGCGCTCGTCGGTTTCCCGAGTGCCGGGAAGTCCTCGCTGGTCTCGGTGCTCAGCGCCGCGCGTCCCAAGATCGC
CGACTACCCGTTCACCACCCTGGTCCCGAACCTGGGCGTCGTCCAGGCCGGTGACCATCGCCCGTTCACGGTCGCGGACG
TCCCCGGGCTGATTCCGGGTGCCAGCCAGGGCCGGGGGCTGGGCCTGGAGTTCCTGCGGCACATCGAGCGGTGCTCGCTG
ATCGTCCACGTTCTCGACTGCGCCACGCTCGAGCCCGGCCGTGATCCGCTCACCGACCTCGACGTGATCGAGGCGGAGCT
CGCCGCGTACACGACCGACCTGTCGGACCGCCCGCGTCTCGTGGTGCTGAACAAGGTCGACGTCCCGGACGCGGCCGAGC
TCGCCGAGCTGGTCACCCCTGACCTGCAAGCCCGCGGTCTGGCCGTGCACCAGATCAGCACGGCGAGCCGGCACGGGGTC
CGCGGGCTCGCGCTCGCGCTCGCCGAGCTCGTCGCCAGCCTGCGCGCCGCGGTGCCCAGCCCGGCCGCGACCCGGATCGT
GCTGCGCCCGCGCGCGGTGGACGAGCCGGACTTCACGGTGCGGGCCGAGGGCGACGGCTTCGTCGTCGGCGGGACCAAAC
CGCTGCGCTGGGTGCGCCAGACCGACTTCAGCAACGAGGAGGCGATCGGCTACCTGGCCGACCGCCTGGCCCGGCTGGGC
GTCGAGAAGGAGCTCGCCAAACGGGGTGCCTTCCCCGGGGTCGCGGTCACGATCGGTGCCGTCACCTTCGACTGGGAGCC
GACGCTGTCCGGCCGGGAGGCGCTGCTCGCCGCCGGCGGCGGGGATGGCGACGGCTACGGCGAGGCGGGCTACGGCGCCG
TCGACACCGCCGTCACGATCGCGACCGTGGGCGGGTCCGGGGGCACGAGAGCCGGCGCGCGCGGCGGAGCAGTGGTCTCC
GACCTCCCGCTCGGCCCGCGGGGCACCGACCTGCGGCTGCGGACGTCCAAGCGGCTCACCAGGGCACAGCGGACGGCCCT
GAGTGACTCCGCTGACGACTTCGACGACGGTGCCGGCTTCAGCGACAGTGCGGCCTTCGGCGACAGCGGTGGCTCCGGCG
GTGACGCCGACGGCGGGCGTGGCTAG

Upstream 100 bases:

>100_bases
ACAGGGCGCCGCGCGAGCCACAGCCCCTCCGGTGTGGCATGCGCGGCGCTCTTGCGCGTCAGACCGCGGTCAACCGCGGA
GTTAGGAGAGGTGGCAGATC

Downstream 100 bases:

>100_bases
GCCGTGGTCCGTTCCTTCGTCACCGAAGCGAACCGGGTCGTCGTCAAGGTCGGCTCGTCGTCGCTGACCACGGCGGCCGG
TGGGCTGGACGCCGACCGGG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 541; Mature: 540

Protein sequence:

>541_residues
MPTFVDRVVLHAAAGDGGHGCCSIHREKFKPLGGPDGGNGGRGGNVLLRVDSGVTTLLDFHFHPHQRAGGGRPGQGSNRH
GADGDDLVLSVPDGTVVLSPDGEQIVDLVGAGSTYVLAHGGRGGRGNASLASARRKAPGFAELGEPGEQLDAVLELKSVA
DVALVGFPSAGKSSLVSVLSAARPKIADYPFTTLVPNLGVVQAGDHRPFTVADVPGLIPGASQGRGLGLEFLRHIERCSL
IVHVLDCATLEPGRDPLTDLDVIEAELAAYTTDLSDRPRLVVLNKVDVPDAAELAELVTPDLQARGLAVHQISTASRHGV
RGLALALAELVASLRAAVPSPAATRIVLRPRAVDEPDFTVRAEGDGFVVGGTKPLRWVRQTDFSNEEAIGYLADRLARLG
VEKELAKRGAFPGVAVTIGAVTFDWEPTLSGREALLAAGGGDGDGYGEAGYGAVDTAVTIATVGGSGGTRAGARGGAVVS
DLPLGPRGTDLRLRTSKRLTRAQRTALSDSADDFDDGAGFSDSAAFGDSGGSGGDADGGRG

Sequences:

>Translated_541_residues
MPTFVDRVVLHAAAGDGGHGCCSIHREKFKPLGGPDGGNGGRGGNVLLRVDSGVTTLLDFHFHPHQRAGGGRPGQGSNRH
GADGDDLVLSVPDGTVVLSPDGEQIVDLVGAGSTYVLAHGGRGGRGNASLASARRKAPGFAELGEPGEQLDAVLELKSVA
DVALVGFPSAGKSSLVSVLSAARPKIADYPFTTLVPNLGVVQAGDHRPFTVADVPGLIPGASQGRGLGLEFLRHIERCSL
IVHVLDCATLEPGRDPLTDLDVIEAELAAYTTDLSDRPRLVVLNKVDVPDAAELAELVTPDLQARGLAVHQISTASRHGV
RGLALALAELVASLRAAVPSPAATRIVLRPRAVDEPDFTVRAEGDGFVVGGTKPLRWVRQTDFSNEEAIGYLADRLARLG
VEKELAKRGAFPGVAVTIGAVTFDWEPTLSGREALLAAGGGDGDGYGEAGYGAVDTAVTIATVGGSGGTRAGARGGAVVS
DLPLGPRGTDLRLRTSKRLTRAQRTALSDSADDFDDGAGFSDSAAFGDSGGSGGDADGGRG
>Mature_540_residues
PTFVDRVVLHAAAGDGGHGCCSIHREKFKPLGGPDGGNGGRGGNVLLRVDSGVTTLLDFHFHPHQRAGGGRPGQGSNRHG
ADGDDLVLSVPDGTVVLSPDGEQIVDLVGAGSTYVLAHGGRGGRGNASLASARRKAPGFAELGEPGEQLDAVLELKSVAD
VALVGFPSAGKSSLVSVLSAARPKIADYPFTTLVPNLGVVQAGDHRPFTVADVPGLIPGASQGRGLGLEFLRHIERCSLI
VHVLDCATLEPGRDPLTDLDVIEAELAAYTTDLSDRPRLVVLNKVDVPDAAELAELVTPDLQARGLAVHQISTASRHGVR
GLALALAELVASLRAAVPSPAATRIVLRPRAVDEPDFTVRAEGDGFVVGGTKPLRWVRQTDFSNEEAIGYLADRLARLGV
EKELAKRGAFPGVAVTIGAVTFDWEPTLSGREALLAAGGGDGDGYGEAGYGAVDTAVTIATVGGSGGTRAGARGGAVVSD
LPLGPRGTDLRLRTSKRLTRAQRTALSDSADDFDDGAGFSDSAAFGDSGGSGGDADGGRG

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=295, Percent_Identity=44.0677966101695, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI111955139, Length=248, Percent_Identity=35.8870967741936, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI111955063, Length=142, Percent_Identity=40.8450704225352, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI58761500, Length=128, Percent_Identity=32.8125, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4758796, Length=119, Percent_Identity=36.1344537815126, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1789574, Length=331, Percent_Identity=41.6918429003021, Blast_Score=231, Evalue=8e-62,
Organism=Escherichia coli, GI1787454, Length=190, Percent_Identity=33.6842105263158, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17508313, Length=334, Percent_Identity=39.2215568862275, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17552324, Length=194, Percent_Identity=33.5051546391753, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17509631, Length=148, Percent_Identity=31.7567567567568, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555344, Length=119, Percent_Identity=35.2941176470588, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=186, Percent_Identity=39.7849462365591, Blast_Score=126, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6319281, Length=127, Percent_Identity=36.2204724409449, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321612, Length=100, Percent_Identity=39, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321649, Length=141, Percent_Identity=29.7872340425532, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI20129375, Length=300, Percent_Identity=40.6666666666667, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24585318, Length=238, Percent_Identity=38.655462184874, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24640873, Length=128, Percent_Identity=33.59375, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24640877, Length=128, Percent_Identity=33.59375, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24640875, Length=128, Percent_Identity=33.59375, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17981711, Length=119, Percent_Identity=36.1344537815126, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356473, Length=155, Percent_Identity=33.5483870967742, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_FRASN (A8L1V6)

Other databases:

- EMBL:   CP000820
- RefSeq:   YP_001509522.1
- ProteinModelPortal:   A8L1V6
- SMR:   A8L1V6
- GeneID:   5673592
- GenomeReviews:   CP000820_GR
- KEGG:   fre:Franean1_5258
- HOGENOM:   HBG716038
- OMA:   IVHVLDC
- ProtClustDB:   PRK12296
- BioCyc:   FSP1855:FRANEAN1_5258-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 55376; Mature: 55244

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTFVDRVVLHAAAGDGGHGCCSIHREKFKPLGGPDGGNGGRGGNVLLRVDSGVTTLLDF
CCHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEE
HFHPHQRAGGGRPGQGSNRHGADGDDLVLSVPDGTVVLSPDGEQIVDLVGAGSTYVLAHG
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCHHHHHHHCCCCEEEEEEC
GRGGRGNASLASARRKAPGFAELGEPGEQLDAVLELKSVADVALVGFPSAGKSSLVSVLS
CCCCCCCCHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHH
AARPKIADYPFTTLVPNLGVVQAGDHRPFTVADVPGLIPGASQGRGLGLEFLRHIERCSL
HCCCCCCCCCHHHHCCCCCEEECCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
IVHVLDCATLEPGRDPLTDLDVIEAELAAYTTDLSDRPRLVVLNKVDVPDAAELAELVTP
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCC
DLQARGLAVHQISTASRHGVRGLALALAELVASLRAAVPSPAATRIVLRPRAVDEPDFTV
CHHHCCEEEEEECHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEE
RAEGDGFVVGGTKPLRWVRQTDFSNEEAIGYLADRLARLGVEKELAKRGAFPGVAVTIGA
EECCCEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCEEEEEEE
VTFDWEPTLSGREALLAAGGGDGDGYGEAGYGAVDTAVTIATVGGSGGTRAGARGGAVVS
EEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEE
DLPLGPRGTDLRLRTSKRLTRAQRTALSDSADDFDDGAGFSDSAAFGDSGGSGGDADGGR
CCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
G
C
>Mature Secondary Structure 
PTFVDRVVLHAAAGDGGHGCCSIHREKFKPLGGPDGGNGGRGGNVLLRVDSGVTTLLDF
CHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEE
HFHPHQRAGGGRPGQGSNRHGADGDDLVLSVPDGTVVLSPDGEQIVDLVGAGSTYVLAHG
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCHHHHHHHCCCCEEEEEEC
GRGGRGNASLASARRKAPGFAELGEPGEQLDAVLELKSVADVALVGFPSAGKSSLVSVLS
CCCCCCCCHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHH
AARPKIADYPFTTLVPNLGVVQAGDHRPFTVADVPGLIPGASQGRGLGLEFLRHIERCSL
HCCCCCCCCCHHHHCCCCCEEECCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
IVHVLDCATLEPGRDPLTDLDVIEAELAAYTTDLSDRPRLVVLNKVDVPDAAELAELVTP
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCC
DLQARGLAVHQISTASRHGVRGLALALAELVASLRAAVPSPAATRIVLRPRAVDEPDFTV
CHHHCCEEEEEECHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEE
RAEGDGFVVGGTKPLRWVRQTDFSNEEAIGYLADRLARLGVEKELAKRGAFPGVAVTIGA
EECCCEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCEEEEEEE
VTFDWEPTLSGREALLAAGGGDGDGYGEAGYGAVDTAVTIATVGGSGGTRAGARGGAVVS
EEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEE
DLPLGPRGTDLRLRTSKRLTRAQRTALSDSADDFDDGAGFSDSAAFGDSGGSGGDADGGR
CCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA