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The map label for this gene is fabG [H]

Identifier: 158317004

GI number: 158317004

Start: 6309619

End: 6310449

Strand: Direct

Name: fabG [H]

Synonym: Franean1_5248

Alternate gene names: 158317004

Gene position: 6309619-6310449 (Clockwise)

Preceding gene: 158317000

Following gene: 158317006

Centisome position: 70.25

GC content: 74.37

Gene sequence:

>831_bases
ATGGCGAGGATCAAGGGATCAGTCGTCCTGGTGACCGGGGCGAACCGGGGGCTGGGGCGGGCGTTTGTCGAGGAGCTGCT
GGCCCGGGGTGCCGCGAAGGTCTACGCGGCCGCGCGCGACCCGCAGTCGGTCCAGACCCCGGGCGCCGTACCGATCCGGC
TGGATGTCAACGACCCGGCCCAGGTGGCCGCGGCGGCCGAGGCGACCGGCGACGTCGACATCCTGATCAACAACGCCGGC
AGCTCGACCGGCGCGTCGGTGCTCACCGGGGACGTCGACGACATCCGCCTGGAGCTGGAGACCCACTTCTTCGGGCCGCT
GCGCACGGTCCGCGCTTTCGCCCCGCAGCTCGCGCGGCACCGCGCCGGCGCCGGCGCGGCGGGTGAGGGCAACGCGAACG
GGAACGGCGCCGGCGGTGCGGGAGCCACGGGGCGCGCGGGCGCGTCCGGTGGGGCGGTGCTCAACGTCCTGTCGGCCCTG
TCGTGGTTGGCGGCGCCGACGAGCGGAGGCTACTGCGCGGCGAAGAGCGCCGCCTGGTCGCTGACGAACTCCCAGCGGCT
GGAGCTGGCCGACCAGGGCGTCGCCGTGACGGCGCTGCACGTCGGCTACATGGACACCGACATGACCCGCGCCATCCAGG
CGCCGAAGTCGGACCCGGCCACCATCGCGGCGCTCGCGCTGGACGGCGTCGAGGCCGGAGCCGCCGAGGTCCTCGCGGAC
GACACGAGCATTCACATCCGGGCGGCGCTGTCGGGTGGGCTCACCGACCTCTATCCGGCGCTCGCCGAGCTCTACTCCTC
GCGCGAGCCCGTGGCCACGCTGACGGGCTGA

Upstream 100 bases:

>100_bases
CGGTGATCCGCAGGGACGGCCGGACATCGGCGACGTCCCGGCCCAGGCGGGGCATGGCCCGGCCGGGGTATGGCGGGCGA
CGAGGGACGGAGCGCGGGCG

Downstream 100 bases:

>100_bases
CCAGCCCCGTCCACCGCATCGTCCACCGGCGGACGGCCCTCCGGCACACTCACGGCCGGCTGGGCCGCCTCCGGGCCGGC
ATCGGCGTCAGTGCCGGCGC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MARIKGSVVLVTGANRGLGRAFVEELLARGAAKVYAAARDPQSVQTPGAVPIRLDVNDPAQVAAAAEATGDVDILINNAG
SSTGASVLTGDVDDIRLELETHFFGPLRTVRAFAPQLARHRAGAGAAGEGNANGNGAGGAGATGRAGASGGAVLNVLSAL
SWLAAPTSGGYCAAKSAAWSLTNSQRLELADQGVAVTALHVGYMDTDMTRAIQAPKSDPATIAALALDGVEAGAAEVLAD
DTSIHIRAALSGGLTDLYPALAELYSSREPVATLTG

Sequences:

>Translated_276_residues
MARIKGSVVLVTGANRGLGRAFVEELLARGAAKVYAAARDPQSVQTPGAVPIRLDVNDPAQVAAAAEATGDVDILINNAG
SSTGASVLTGDVDDIRLELETHFFGPLRTVRAFAPQLARHRAGAGAAGEGNANGNGAGGAGATGRAGASGGAVLNVLSAL
SWLAAPTSGGYCAAKSAAWSLTNSQRLELADQGVAVTALHVGYMDTDMTRAIQAPKSDPATIAALALDGVEAGAAEVLAD
DTSIHIRAALSGGLTDLYPALAELYSSREPVATLTG
>Mature_275_residues
ARIKGSVVLVTGANRGLGRAFVEELLARGAAKVYAAARDPQSVQTPGAVPIRLDVNDPAQVAAAAEATGDVDILINNAGS
STGASVLTGDVDDIRLELETHFFGPLRTVRAFAPQLARHRAGAGAAGEGNANGNGAGGAGATGRAGASGGAVLNVLSALS
WLAAPTSGGYCAAKSAAWSLTNSQRLELADQGVAVTALHVGYMDTDMTRAIQAPKSDPATIAALALDGVEAGAAEVLADD
TSIHIRAALSGGLTDLYPALAELYSSREPVATLTG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=226, Percent_Identity=26.5486725663717, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1787335, Length=219, Percent_Identity=26.9406392694064, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27609; Mature: 27478

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARIKGSVVLVTGANRGLGRAFVEELLARGAAKVYAAARDPQSVQTPGAVPIRLDVNDPA
CCEECCCEEEEECCCCCHHHHHHHHHHHCCHHEEEEECCCCCCCCCCCCEEEEEECCCHH
QVAAAAEATGDVDILINNAGSSTGASVLTGDVDDIRLELETHFFGPLRTVRAFAPQLARH
HHHHHHCCCCCEEEEEECCCCCCCCEEEECCCCCEEEEEEHHCCCHHHHHHHHHHHHHHH
RAGAGAAGEGNANGNGAGGAGATGRAGASGGAVLNVLSALSWLAAPTSGGYCAAKSAAWS
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCEEE
LTNSQRLELADQGVAVTALHVGYMDTDMTRAIQAPKSDPATIAALALDGVEAGAAEVLAD
CCCCCEEEHHCCCEEEEEEEECCCCCHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHEEC
DTSIHIRAALSGGLTDLYPALAELYSSREPVATLTG
CCCEEEEEEECCCHHHHHHHHHHHHCCCCCEEECCC
>Mature Secondary Structure 
ARIKGSVVLVTGANRGLGRAFVEELLARGAAKVYAAARDPQSVQTPGAVPIRLDVNDPA
CEECCCEEEEECCCCCHHHHHHHHHHHCCHHEEEEECCCCCCCCCCCCEEEEEECCCHH
QVAAAAEATGDVDILINNAGSSTGASVLTGDVDDIRLELETHFFGPLRTVRAFAPQLARH
HHHHHHCCCCCEEEEEECCCCCCCCEEEECCCCCEEEEEEHHCCCHHHHHHHHHHHHHHH
RAGAGAAGEGNANGNGAGGAGATGRAGASGGAVLNVLSALSWLAAPTSGGYCAAKSAAWS
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCEEE
LTNSQRLELADQGVAVTALHVGYMDTDMTRAIQAPKSDPATIAALALDGVEAGAAEVLAD
CCCCCEEEHHCCCEEEEEEEECCCCCHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHEEC
DTSIHIRAALSGGLTDLYPALAELYSSREPVATLTG
CCCEEEEEEECCCHHHHHHHHHHHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1556094; 8905232; 9278503; 1314802 [H]