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The map label for this gene is qacA [H]

Identifier: 158316976

GI number: 158316976

Start: 6266093

End: 6267769

Strand: Reverse

Name: qacA [H]

Synonym: Franean1_5220

Alternate gene names: 158316976

Gene position: 6267769-6266093 (Counterclockwise)

Preceding gene: 158316978

Following gene: 158316975

Centisome position: 69.78

GC content: 74.3

Gene sequence:

>1677_bases
GTGCCCGCTGACCCCGACGCCCACGCCCACGCGGTGCCGGCGGGACGGGCCGGCCGGCGGGAGTGGACCGGGCTGGCCGT
CCTCGCGCTGCCCACGCTGCTGCTGTCGCTGGACCTGAGCGTTCTCTACCTCGCGCTGCCCGGCCTCACCGAGGACCTGC
GGCCCAGCGCCACGCAGCTGCTGTGGATCACCGACAGCTACGGCTTCCTGATCGCCGGCTTCCTGGTGACCATGGGAACC
CTCGGCGACCGCGTGGGCCGGCGCCGCCTCCTGCTCGCCGGCGCGGTCGCGTTCGCGCTGACGTCCGTGCTGGCGGCCTG
GGCGACGAGCCCGACGATGCTGATCGCCGCGCGGGCCCTGCTCGGGATCGCCGGTGCCACGCTCATGCCGTCCACCCTCG
CGCTGATCAGCAACATGTTCACCGACGAACGGCAGCGGTCCACCGCGGTCGCCGTCTGGATGAGCTGCTTCCTCGCCGGG
ATGGCGGCCGGCCCGGTGCTCGGCGGCCTGCTGCTGGAGTACTTCTGGTGGGGTTCGGTGTTCCTGCTCGGCGTACCGGT
CATGGCGCTGCTGGTCGTGACGGCGCCCGTGCTGCTGCCCGAGTACCGGCACCCGGGGGAGGGCCGCCTCGACCTGGTCA
GCGCGACGATGTCGCTGCTCGCCGTCCTCGCGGTCGTCAACGGGCTCAAGGAGACGGCGGCGGGTGGTCCGGGCCCGGGT
GCCGGCGGGTCGGTCGCGGTCGGGCTGCTGGTCGGCTGGCTGTTCATCCGCCGCCAGCGCGGCCGGGCCGACCCGTTCGT
GGACATCGGCCTGTTCGCGAACCGGTCGTTCACGGCCGCGCTCGGGCTCATCCTGTTCGGCGCGTTCGTCATGGGCGGGA
TCAACCTGTTCGTGACGCAGTACCTGCAGCTGGTCGCGGGACTCACCCCGCTGCGGGCCGGCCTGTGGCTGGCGCCGGCG
ACGCTGGCCGTCATCGGCACGAGCCTGGCCGCCCCGGTGGCGGCGCGGTGGATCGGCGCGGGGCGGGTGGTCGCCGCCGG
GCTGGGGGTGAGCGCCGTCGGCCTCGCGATCCTCACCCGGGCCGGCGATGGCGGGCTGATCCTGCTGGGGTTCGGGTTCG
TCCTGGTCTTCCTGGGTGTCGGGCCGCTGGGCGTGCTCGGCACCGATCTGGTGGTCGGATCAGCGCCGCCCGCGCGGGCC
GGGTCGGCGGCATCGCTGTCGGAGACGGGCAGCGAGCTGGGCGTGGCCCTCGGGGTGGCGCTGCTCGGCAGCCTGGGCAC
GGCCGTCTACCGGCACCGCCTCGCCGCGGCGATCGACAGCGGGAGCCCGGCCGGGGGAGCGGGTCGGTCGGCACCGGCCG
GGCCGGCCGATGCCGACCGTGAAAGCCTCGCCGGTGCGGTACGGGCGGCGCGATCACTCGCCGACGGCGGAACCGCGGTG
CTGGAGCCGGCCCGCGACGCGTTCACCGCCGGCCTGCACACCGTCGCCGCGGTGGGATGCGCGCTGGCGGTTCTGTTCGC
GGTGCTCTCGGTCCTCCTCTTCCGCAGCGGCGCGGTGGGTGGCATGACGGCGAGCGACTCGACAACGGGTGACGTCACAG
CCGCTGAACAGACCATCGGAATGAATTCCGATGAAGAGGACGGAGCTGCGGACGGACGGGGCGACGCGGCGTTCTGA

Upstream 100 bases:

>100_bases
GACCCGCTCGGCGCGGGGCGGATCCGCCCGGCGGGACGCGCGGACACGCACGGCGGGATCGAGGTGAGCGCGAGGCCCGT
GCCCGGGGAGGATGACCGGC

Downstream 100 bases:

>100_bases
AGGACACTTCGTAACCCGCATGGGCGGAACACGGCCGCGTGTTCTGTTTGTCCGGTCCTGGCGACGGATGTCGTCATAAC
CGAGTGGCGGCAGGTACGGG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MPADPDAHAHAVPAGRAGRREWTGLAVLALPTLLLSLDLSVLYLALPGLTEDLRPSATQLLWITDSYGFLIAGFLVTMGT
LGDRVGRRRLLLAGAVAFALTSVLAAWATSPTMLIAARALLGIAGATLMPSTLALISNMFTDERQRSTAVAVWMSCFLAG
MAAGPVLGGLLLEYFWWGSVFLLGVPVMALLVVTAPVLLPEYRHPGEGRLDLVSATMSLLAVLAVVNGLKETAAGGPGPG
AGGSVAVGLLVGWLFIRRQRGRADPFVDIGLFANRSFTAALGLILFGAFVMGGINLFVTQYLQLVAGLTPLRAGLWLAPA
TLAVIGTSLAAPVAARWIGAGRVVAAGLGVSAVGLAILTRAGDGGLILLGFGFVLVFLGVGPLGVLGTDLVVGSAPPARA
GSAASLSETGSELGVALGVALLGSLGTAVYRHRLAAAIDSGSPAGGAGRSAPAGPADADRESLAGAVRAARSLADGGTAV
LEPARDAFTAGLHTVAAVGCALAVLFAVLSVLLFRSGAVGGMTASDSTTGDVTAAEQTIGMNSDEEDGAADGRGDAAF

Sequences:

>Translated_558_residues
MPADPDAHAHAVPAGRAGRREWTGLAVLALPTLLLSLDLSVLYLALPGLTEDLRPSATQLLWITDSYGFLIAGFLVTMGT
LGDRVGRRRLLLAGAVAFALTSVLAAWATSPTMLIAARALLGIAGATLMPSTLALISNMFTDERQRSTAVAVWMSCFLAG
MAAGPVLGGLLLEYFWWGSVFLLGVPVMALLVVTAPVLLPEYRHPGEGRLDLVSATMSLLAVLAVVNGLKETAAGGPGPG
AGGSVAVGLLVGWLFIRRQRGRADPFVDIGLFANRSFTAALGLILFGAFVMGGINLFVTQYLQLVAGLTPLRAGLWLAPA
TLAVIGTSLAAPVAARWIGAGRVVAAGLGVSAVGLAILTRAGDGGLILLGFGFVLVFLGVGPLGVLGTDLVVGSAPPARA
GSAASLSETGSELGVALGVALLGSLGTAVYRHRLAAAIDSGSPAGGAGRSAPAGPADADRESLAGAVRAARSLADGGTAV
LEPARDAFTAGLHTVAAVGCALAVLFAVLSVLLFRSGAVGGMTASDSTTGDVTAAEQTIGMNSDEEDGAADGRGDAAF
>Mature_557_residues
PADPDAHAHAVPAGRAGRREWTGLAVLALPTLLLSLDLSVLYLALPGLTEDLRPSATQLLWITDSYGFLIAGFLVTMGTL
GDRVGRRRLLLAGAVAFALTSVLAAWATSPTMLIAARALLGIAGATLMPSTLALISNMFTDERQRSTAVAVWMSCFLAGM
AAGPVLGGLLLEYFWWGSVFLLGVPVMALLVVTAPVLLPEYRHPGEGRLDLVSATMSLLAVLAVVNGLKETAAGGPGPGA
GGSVAVGLLVGWLFIRRQRGRADPFVDIGLFANRSFTAALGLILFGAFVMGGINLFVTQYLQLVAGLTPLRAGLWLAPAT
LAVIGTSLAAPVAARWIGAGRVVAAGLGVSAVGLAILTRAGDGGLILLGFGFVLVFLGVGPLGVLGTDLVVGSAPPARAG
SAASLSETGSELGVALGVALLGSLGTAVYRHRLAAAIDSGSPAGGAGRSAPAGPADADRESLAGAVRAARSLADGGTAVL
EPARDAFTAGLHTVAAVGCALAVLFAVLSVLLFRSGAVGGMTASDSTTGDVTAAEQTIGMNSDEEDGAADGRGDAAF

Specific function: Confers export-mediated resistance against antiseptic and disinfectant compounds such as intercalating dyes, quaternary ammonium salts and diamidines [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=401, Percent_Identity=30.6733167082294, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789042, Length=455, Percent_Identity=25.9340659340659, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1788710, Length=516, Percent_Identity=24.4186046511628, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788392, Length=437, Percent_Identity=29.7482837528604, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1790195, Length=325, Percent_Identity=25.8461538461538, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 56099; Mature: 55968

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPADPDAHAHAVPAGRAGRREWTGLAVLALPTLLLSLDLSVLYLALPGLTEDLRPSATQL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
LWITDSYGFLIAGFLVTMGTLGDRVGRRRLLLAGAVAFALTSVLAAWATSPTMLIAARAL
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LGIAGATLMPSTLALISNMFTDERQRSTAVAVWMSCFLAGMAAGPVLGGLLLEYFWWGSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLGVPVMALLVVTAPVLLPEYRHPGEGRLDLVSATMSLLAVLAVVNGLKETAAGGPGPG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AGGSVAVGLLVGWLFIRRQRGRADPFVDIGLFANRSFTAALGLILFGAFVMGGINLFVTQ
CCHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YLQLVAGLTPLRAGLWLAPATLAVIGTSLAAPVAARWIGAGRVVAAGLGVSAVGLAILTR
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHC
AGDGGLILLGFGFVLVFLGVGPLGVLGTDLVVGSAPPARAGSAASLSETGSELGVALGVA
CCCCCEEHHHHHHHHHHHCCCCHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
LLGSLGTAVYRHRLAAAIDSGSPAGGAGRSAPAGPADADRESLAGAVRAARSLADGGTAV
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHH
LEPARDAFTAGLHTVAAVGCALAVLFAVLSVLLFRSGAVGGMTASDSTTGDVTAAEQTIG
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCC
MNSDEEDGAADGRGDAAF
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PADPDAHAHAVPAGRAGRREWTGLAVLALPTLLLSLDLSVLYLALPGLTEDLRPSATQL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE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CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]