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The map label for this gene is trkA [H]

Identifier: 158316948

GI number: 158316948

Start: 6234920

End: 6235699

Strand: Direct

Name: trkA [H]

Synonym: Franean1_5192

Alternate gene names: 158316948

Gene position: 6234920-6235699 (Clockwise)

Preceding gene: 158316947

Following gene: 158316953

Centisome position: 69.42

GC content: 73.59

Gene sequence:

>780_bases
ATGACCGCGGATCCGGACGCGCGTACCGGGGGCACCGAACAGGACGGGGCCGCCGAGCGGAGCGGGGTGGCGAACCGGCG
GGTGGCGATCGCGGGCGCCGGCAAGGTCGGCCGCTCGATCGCCGCGGAGCTGCTGGAGAACGGCTCCGAGGTGCTCATCA
TCGAGCGCGACCCGAACAAGATCCGCCGGGACGCGCTGCCCGCGGCGGACTGGCTGCTCGCCGACGCCTGCGAGCTGTCC
TCCCTCGACGGCGCCGGCCTGGACTGCTGCGCGGTGATGGTCGCCGCCACCGGCGACGACAAGGTCAACCTCGTGGTCTC
GCTGTTGGCGAAGACCGAGTTCGGCGTGCCCAGGGTGGTCGCGCGGGTCAACCATCCCAAGAACGAGTGGCTGTTCACCG
AGTCCTGGGGCGTCGACGTGGCGGTGTCCGCGCCGCGCATGCTGACCGCGCTGGTCGAGGAGGCGGTGAGCGTCGGTGAC
CTGGTGCGCCTGATGAAGTTCCGCCAGGGCGACGCCTCCCTCGTCGAGCTCACCCTGACCGCGGACGCGCCCGTCGTGGG
CCGGCGGCTGGGCGACGTCGACCTCCCGCCGGACTCCGCCGTCGTCGTGATCCTGCGGGACGGCAACGCGGTGGTCCCGT
CGCCGGACAGCACGCTCGAGCCGGGCGACGAGGTGCTGGCCGTCGCGACCACGAGCGAGGCCGAGGAGAGCCTCGCGGCG
CTGCTCGGCGCCGTCCCCGCCGACGCCAGCCGGAACCAGCGCGTCTCCGGAGTGCTCTAG

Upstream 100 bases:

>100_bases
GTCCTGCACGTCGCGGTCGCCAAGGCGCGGGCCACCGAGGCGGACGCGATCATCCGCACCGGCCCCGACCACGACTGACG
ACGAGAGACGAGGACCTGCG

Downstream 100 bases:

>100_bases
CCGATCCCGGTCGTCGCGCCGGGGGTTCGGCGCGGTCTGTCAGTCGTTCGGGATGCCCGCGGCGAGCTGGCCGGGTTCGC
CGGTCTGACCGTCCTCCCCG

Product: TrkA domain-containing protein

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MTADPDARTGGTEQDGAAERSGVANRRVAIAGAGKVGRSIAAELLENGSEVLIIERDPNKIRRDALPAADWLLADACELS
SLDGAGLDCCAVMVAATGDDKVNLVVSLLAKTEFGVPRVVARVNHPKNEWLFTESWGVDVAVSAPRMLTALVEEAVSVGD
LVRLMKFRQGDASLVELTLTADAPVVGRRLGDVDLPPDSAVVVILRDGNAVVPSPDSTLEPGDEVLAVATTSEAEESLAA
LLGAVPADASRNQRVSGVL

Sequences:

>Translated_259_residues
MTADPDARTGGTEQDGAAERSGVANRRVAIAGAGKVGRSIAAELLENGSEVLIIERDPNKIRRDALPAADWLLADACELS
SLDGAGLDCCAVMVAATGDDKVNLVVSLLAKTEFGVPRVVARVNHPKNEWLFTESWGVDVAVSAPRMLTALVEEAVSVGD
LVRLMKFRQGDASLVELTLTADAPVVGRRLGDVDLPPDSAVVVILRDGNAVVPSPDSTLEPGDEVLAVATTSEAEESLAA
LLGAVPADASRNQRVSGVL
>Mature_258_residues
TADPDARTGGTEQDGAAERSGVANRRVAIAGAGKVGRSIAAELLENGSEVLIIERDPNKIRRDALPAADWLLADACELSS
LDGAGLDCCAVMVAATGDDKVNLVVSLLAKTEFGVPRVVARVNHPKNEWLFTESWGVDVAVSAPRMLTALVEEAVSVGDL
VRLMKFRQGDASLVELTLTADAPVVGRRLGDVDLPPDSAVVVILRDGNAVVPSPDSTLEPGDEVLAVATTSEAEESLAAL
LGAVPADASRNQRVSGVL

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=233, Percent_Identity=21.0300429184549, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 26910; Mature: 26778

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTADPDARTGGTEQDGAAERSGVANRRVAIAGAGKVGRSIAAELLENGSEVLIIERDPNK
CCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCHH
IRRDALPAADWLLADACELSSLDGAGLDCCAVMVAATGDDKVNLVVSLLAKTEFGVPRVV
HHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCHHHH
ARVNHPKNEWLFTESWGVDVAVSAPRMLTALVEEAVSVGDLVRLMKFRQGDASLVELTLT
HHCCCCCCCEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
ADAPVVGRRLGDVDLPPDSAVVVILRDGNAVVPSPDSTLEPGDEVLAVATTSEAEESLAA
CCCCHHHHHCCCCCCCCCCEEEEEEECCCEECCCCCCCCCCCCCEEEEEECCHHHHHHHH
LLGAVPADASRNQRVSGVL
HHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TADPDARTGGTEQDGAAERSGVANRRVAIAGAGKVGRSIAAELLENGSEVLIIERDPNK
CCCCCCCCCCCCCCCCHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCHH
IRRDALPAADWLLADACELSSLDGAGLDCCAVMVAATGDDKVNLVVSLLAKTEFGVPRVV
HHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCHHHH
ARVNHPKNEWLFTESWGVDVAVSAPRMLTALVEEAVSVGDLVRLMKFRQGDASLVELTLT
HHCCCCCCCEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
ADAPVVGRRLGDVDLPPDSAVVVILRDGNAVVPSPDSTLEPGDEVLAVATTSEAEESLAA
CCCCHHHHHCCCCCCCCCCEEEEEEECCCEECCCCCCCCCCCCCEEEEEECCHHHHHHHH
LLGAVPADASRNQRVSGVL
HHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 9784509 [H]