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The map label for this gene is ygcA [C]

Identifier: 158316945

GI number: 158316945

Start: 6230145

End: 6231698

Strand: Reverse

Name: ygcA [C]

Synonym: Franean1_5189

Alternate gene names: 158316945

Gene position: 6231698-6230145 (Counterclockwise)

Preceding gene: 158316946

Following gene: 158316944

Centisome position: 69.38

GC content: 78.06

Gene sequence:

>1554_bases
GTGACGCGCCCCGTCCCCGTCCCGCCCAGCGAACTGGTGGAGCTTGACGTCGGCCCGGTCGCGCACCGTGGGCTCTGTGT
GGCCCGCGCCGGCGGTCGGGTCGTGTTCGTGCGTCACGCGCTGCCCGGCGAGCGGGTACGGGTCCGGATCACCGACGTCT
CCCACGACCGTTACTGGCGCGCCGACGCCGTCGAGATCCTCGTCGCCTCCCCGGACCGGGTGGCGGCCCCCTGCCCGCAC
GCGCGTCCCGGCGGGTGCGGAGGGTGCGACTGGCAGCACGCCACGCCCGCCGCGCAGCGCCGGCTCAAGGCGCGGGTGGT
CGAGGACGCGCTGCGGCGGCTGGCCGGCCTCGACCGCGCCGTGCTGGTCGAGGCGTTGCCGTCGGAGGGGCCTGACGGGC
TGGGCTGGCGCACCAGGATGCGCTTCTCGCGGACGTCCGACGGCGGCGTCGGGCTGCGCGCGCACCGCTCCCACGAGGTG
GTGCCCACTCCTGACTGCAAGATCGCTCATCCGCTGCTCGCCCGGGTGATCGCCGACCCGGTCTTCCTGACCGGCGACGG
CTCGCCCGAGGTGACCGGCCAGGCGGTGGAGCTCGTGGCGATGCCCGGCGACGCCGTGGCGTACTCGACGCGGTCCGGCG
GGTGGCGCGTCACCGAGACCGGCCCCGCCGCCGCCGACGCCGAGGGCACCGGCGCCACCCGCGTCGACGGCGCCACCCGC
GTCGACGGCGCCACCCGCGTCGACGGCGCCACCCGCGTCGACGGCGCCGACGGCGCCGATCCCGACAGTGCTCTTCGTGC
CAGTGCCGTTCCCGTCCGCACCGGTCCTGACCGCGGCGAGCCGGCGCCGGTCGAGGTGGTCGAGACGGTCGAAGGCCGCG
AGTTCCGGCTGGAGCCGGGGGTCTTCTGGCAGGTCCACCCGGCCGCCGCGGCGACGCTGGTCGCCGCGGTGCGCGAGGCG
GCCGCGGCCGCGGCGGGGGACACGGCCCTCGACCTGTACTGCGGGGCAGGGCTGTTCGCCGCGTTCCTCGCCGAGGCGGT
CGGACCGACCGGGCGGGTCATCGCGCTGGAATCCGACGAGGCCGCCGTCCGCTCCGCCGCGCGGAGCCTGGCTGACCTGC
CCTGGGTGTCGCTGCGTTCCCTGAGGGTGACCCCGGCGACGGTCCGCGGCCTCGTCGGCGCGGCGGACCAGCCGGCCGCG
CCCGCCGACGGCCTCCCGGCCGGCGGCGCCACGCCCGGCCCGGCCCGGCGGGCGGTGGACGTCGCGGTGCTCGACCCGCC
GCGGACCGGCACGGGTCGTGAGGTCATGACCGAGCTTCTCGCGCACCGGCCGCGCCGGGTCGTCTACGTGGCCTGCGACC
CCGCCGCGCTCGCGCGGGACGTGGCGGTCGCGGCGGGCGAGGGGTATCGGCTCACCGAGCTCCGCGCGTTCGACCTGTTC
CCGATGACCTCGCACGTGGAGTGCGTGGCGACCTTGGAGCCCGCGCCCGCGGGCGCGACCGGCTCCGCGGAGCCGGCCCG
GCCAGGCACGGGCAGCACGGCGCTACCGCGATGA

Upstream 100 bases:

>100_bases
CCGGCACCGCGCCGGCGACGCCGCCCGGGACCGCGCCGGCGATACCAGCCGGGACCGGCCGGAGCGGGCCGATCGGGACC
GGACCGACAGGGTGGGCGGG

Downstream 100 bases:

>100_bases
CCGTTGACGGCCACGTGGCCGCGCCGCAAGGCTTTGTGTTCATGCCCCGAACGCCGCCCGGCTCCCAGTCGTCGCTGCGC
GCGGCCAACCGGGACCGGGT

Product: deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MTRPVPVPPSELVELDVGPVAHRGLCVARAGGRVVFVRHALPGERVRVRITDVSHDRYWRADAVEILVASPDRVAAPCPH
ARPGGCGGCDWQHATPAAQRRLKARVVEDALRRLAGLDRAVLVEALPSEGPDGLGWRTRMRFSRTSDGGVGLRAHRSHEV
VPTPDCKIAHPLLARVIADPVFLTGDGSPEVTGQAVELVAMPGDAVAYSTRSGGWRVTETGPAAADAEGTGATRVDGATR
VDGATRVDGATRVDGADGADPDSALRASAVPVRTGPDRGEPAPVEVVETVEGREFRLEPGVFWQVHPAAAATLVAAVREA
AAAAAGDTALDLYCGAGLFAAFLAEAVGPTGRVIALESDEAAVRSAARSLADLPWVSLRSLRVTPATVRGLVGAADQPAA
PADGLPAGGATPGPARRAVDVAVLDPPRTGTGREVMTELLAHRPRRVVYVACDPAALARDVAVAAGEGYRLTELRAFDLF
PMTSHVECVATLEPAPAGATGSAEPARPGTGSTALPR

Sequences:

>Translated_517_residues
MTRPVPVPPSELVELDVGPVAHRGLCVARAGGRVVFVRHALPGERVRVRITDVSHDRYWRADAVEILVASPDRVAAPCPH
ARPGGCGGCDWQHATPAAQRRLKARVVEDALRRLAGLDRAVLVEALPSEGPDGLGWRTRMRFSRTSDGGVGLRAHRSHEV
VPTPDCKIAHPLLARVIADPVFLTGDGSPEVTGQAVELVAMPGDAVAYSTRSGGWRVTETGPAAADAEGTGATRVDGATR
VDGATRVDGATRVDGADGADPDSALRASAVPVRTGPDRGEPAPVEVVETVEGREFRLEPGVFWQVHPAAAATLVAAVREA
AAAAAGDTALDLYCGAGLFAAFLAEAVGPTGRVIALESDEAAVRSAARSLADLPWVSLRSLRVTPATVRGLVGAADQPAA
PADGLPAGGATPGPARRAVDVAVLDPPRTGTGREVMTELLAHRPRRVVYVACDPAALARDVAVAAGEGYRLTELRAFDLF
PMTSHVECVATLEPAPAGATGSAEPARPGTGSTALPR
>Mature_516_residues
TRPVPVPPSELVELDVGPVAHRGLCVARAGGRVVFVRHALPGERVRVRITDVSHDRYWRADAVEILVASPDRVAAPCPHA
RPGGCGGCDWQHATPAAQRRLKARVVEDALRRLAGLDRAVLVEALPSEGPDGLGWRTRMRFSRTSDGGVGLRAHRSHEVV
PTPDCKIAHPLLARVIADPVFLTGDGSPEVTGQAVELVAMPGDAVAYSTRSGGWRVTETGPAAADAEGTGATRVDGATRV
DGATRVDGATRVDGADGADPDSALRASAVPVRTGPDRGEPAPVEVVETVEGREFRLEPGVFWQVHPAAAATLVAAVREAA
AAAAGDTALDLYCGAGLFAAFLAEAVGPTGRVIALESDEAAVRSAARSLADLPWVSLRSLRVTPATVRGLVGAADQPAAP
ADGLPAGGATPGPARRAVDVAVLDPPRTGTGREVMTELLAHRPRRVVYVACDPAALARDVAVAAGEGYRLTELRAFDLFP
MTSHVECVATLEPAPAGATGSAEPARPGTGSTALPR

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Escherichia coli, GI1789148, Length=500, Percent_Identity=26.4, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787083, Length=196, Percent_Identity=26.0204081632653, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR002792
- InterPro:   IPR010280 [H]

Pfam domain/function: PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 53490; Mature: 53359

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50926 TRAM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPVPVPPSELVELDVGPVAHRGLCVARAGGRVVFVRHALPGERVRVRITDVSHDRYWR
CCCCCCCCHHHHEEECCCCCCCCCEEEEECCCEEEEEEECCCCCEEEEEEEECCCCCEEC
ADAVEILVASPDRVAAPCPHARPGGCGGCDWQHATPAAQRRLKARVVEDALRRLAGLDRA
CCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
VLVEALPSEGPDGLGWRTRMRFSRTSDGGVGLRAHRSHEVVPTPDCKIAHPLLARVIADP
HHHHHCCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCC
VFLTGDGSPEVTGQAVELVAMPGDAVAYSTRSGGWRVTETGPAAADAEGTGATRVDGATR
EEEECCCCCCCCCCEEEEEECCCCEEEEEECCCCEEEEECCCCCCCCCCCCCEECCCCCC
VDGATRVDGATRVDGADGADPDSALRASAVPVRTGPDRGEPAPVEVVETVEGREFRLEPG
CCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHEECCCCCEEEECCC
VFWQVHPAAAATLVAAVREAAAAAAGDTALDLYCGAGLFAAFLAEAVGPTGRVIALESDE
CEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCH
AAVRSAARSLADLPWVSLRSLRVTPATVRGLVGAADQPAAPADGLPAGGATPGPARRAVD
HHHHHHHHHHHCCCCHHHHEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEE
VAVLDPPRTGTGREVMTELLAHRPRRVVYVACDPAALARDVAVAAGEGYRLTELRAFDLF
EEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHEECCCCEEEEEEEEEECC
PMTSHVECVATLEPAPAGATGSAEPARPGTGSTALPR
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRPVPVPPSELVELDVGPVAHRGLCVARAGGRVVFVRHALPGERVRVRITDVSHDRYWR
CCCCCCCHHHHEEECCCCCCCCCEEEEECCCEEEEEEECCCCCEEEEEEEECCCCCEEC
ADAVEILVASPDRVAAPCPHARPGGCGGCDWQHATPAAQRRLKARVVEDALRRLAGLDRA
CCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
VLVEALPSEGPDGLGWRTRMRFSRTSDGGVGLRAHRSHEVVPTPDCKIAHPLLARVIADP
HHHHHCCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCC
VFLTGDGSPEVTGQAVELVAMPGDAVAYSTRSGGWRVTETGPAAADAEGTGATRVDGATR
EEEECCCCCCCCCCEEEEEECCCCEEEEEECCCCEEEEECCCCCCCCCCCCCEECCCCCC
VDGATRVDGATRVDGADGADPDSALRASAVPVRTGPDRGEPAPVEVVETVEGREFRLEPG
CCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHEECCCCCEEEECCC
VFWQVHPAAAATLVAAVREAAAAAAGDTALDLYCGAGLFAAFLAEAVGPTGRVIALESDE
CEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCH
AAVRSAARSLADLPWVSLRSLRVTPATVRGLVGAADQPAAPADGLPAGGATPGPARRAVD
HHHHHHHHHHHCCCCHHHHEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEE
VAVLDPPRTGTGREVMTELLAHRPRRVVYVACDPAALARDVAVAAGEGYRLTELRAFDLF
EEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHEECCCCEEEEEEEEEECC
PMTSHVECVATLEPAPAGATGSAEPARPGTGSTALPR
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]