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The map label for this gene is lspA [H]

Identifier: 158316844

GI number: 158316844

Start: 6087548

End: 6088279

Strand: Reverse

Name: lspA [H]

Synonym: Franean1_5087

Alternate gene names: 158316844

Gene position: 6088279-6087548 (Counterclockwise)

Preceding gene: 158316846

Following gene: 158316843

Centisome position: 67.78

GC content: 74.45

Gene sequence:

>732_bases
ATGGACAAGGGCGTCCCGTACAGGAACACCCAGTACGGGAGCACCGTGAACGCCGGTGCGGCGGGAGTGGGTGCCCCGGG
TGCCGCTGACGCGGGCGGCGGCGCCCCGAGCGGTGACGCCGCGGTCAGGCCCGACCGTGACCGCCTGGTCACCTCGCACC
GTGCGGTGCTCGTCGTCGCGCTGACCGCGCTGTGTCTGATCGTCCTGGACATCGGCACGAAGCTGCTGGCCGTCGCCCAG
CTCACCGGGCGCGCCCCGATCGAGATCATCCCCGGCGTGCTCGACCTGCGCCTGACCCGGAACTCGGGGGCCGCGTTCAG
CCTGGCCGGCGGGGCCACGGTCATCCTCAGCCTGATCGCGCTGGCGGTCGTCGCGGTGGTCGTGGTCACCGCCAGGCGGC
TGGCCTCCATCGGGTGGGCGTTCGTCTTCGGCGCGATGGTCGGCGGCGCGCTGGGTAACCTGATCGACCGGCTGTTCCGC
GCCCCCGGGCCGCTGCGCGGGCACGTCGTGGACTTCGTCCACATCCACCACTGGCCCATCTTCAACGTCGCCGACTCGGC
GATCGTCTGCGGCGGAGTGCTCGCGGTCATCCTCTCCCTGCGCGGCATCGGCCTCGACGGCACGCGCCTCTCCGCCGCCC
CGCCACCCGACCCCGGGTCAGCGGAGCCGGCCGGACCATCCGGTCCGGCGGGGCCGAGCCACGCCGGCGGTCCCGGGCCC
GGTGGCGCGTGA

Upstream 100 bases:

>100_bases
GCCGGGTCTCGGGTCGTGTCTCGGGCCGGTGGCCGGCCGGCGGGCGGGTGACCCGTGAGATCGCACCCGTACAGTGGTGT
GTGTGGTGGCCGAGCCGGGG

Downstream 100 bases:

>100_bases
GCACGGCCGACACCGACCGGCGCTCGCTGCCGGTCCCCGACGGCCTCGACGGCATCCGCCTGGACGCCGCCATCGCCCGC
ATGTTCGGCCTGAGCCGCAC

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MDKGVPYRNTQYGSTVNAGAAGVGAPGAADAGGGAPSGDAAVRPDRDRLVTSHRAVLVVALTALCLIVLDIGTKLLAVAQ
LTGRAPIEIIPGVLDLRLTRNSGAAFSLAGGATVILSLIALAVVAVVVVTARRLASIGWAFVFGAMVGGALGNLIDRLFR
APGPLRGHVVDFVHIHHWPIFNVADSAIVCGGVLAVILSLRGIGLDGTRLSAAPPPDPGSAEPAGPSGPAGPSHAGGPGP
GGA

Sequences:

>Translated_243_residues
MDKGVPYRNTQYGSTVNAGAAGVGAPGAADAGGGAPSGDAAVRPDRDRLVTSHRAVLVVALTALCLIVLDIGTKLLAVAQ
LTGRAPIEIIPGVLDLRLTRNSGAAFSLAGGATVILSLIALAVVAVVVVTARRLASIGWAFVFGAMVGGALGNLIDRLFR
APGPLRGHVVDFVHIHHWPIFNVADSAIVCGGVLAVILSLRGIGLDGTRLSAAPPPDPGSAEPAGPSGPAGPSHAGGPGP
GGA
>Mature_243_residues
MDKGVPYRNTQYGSTVNAGAAGVGAPGAADAGGGAPSGDAAVRPDRDRLVTSHRAVLVVALTALCLIVLDIGTKLLAVAQ
LTGRAPIEIIPGVLDLRLTRNSGAAFSLAGGATVILSLIALAVVAVVVVTARRLASIGWAFVFGAMVGGALGNLIDRLFR
APGPLRGHVVDFVHIHHWPIFNVADSAIVCGGVLAVILSLRGIGLDGTRLSAAPPPDPGSAEPAGPSGPAGPSHAGGPGP
GGA

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 24031; Mature: 24031

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKGVPYRNTQYGSTVNAGAAGVGAPGAADAGGGAPSGDAAVRPDRDRLVTSHRAVLVVA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LTALCLIVLDIGTKLLAVAQLTGRAPIEIIPGVLDLRLTRNSGAAFSLAGGATVILSLIA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCEEEEEECCCCCEEEECCHHHHHHHHHH
LAVVAVVVVTARRLASIGWAFVFGAMVGGALGNLIDRLFRAPGPLRGHVVDFVHIHHWPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEECCCCC
FNVADSAIVCGGVLAVILSLRGIGLDGTRLSAAPPPDPGSAEPAGPSGPAGPSHAGGPGP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GGA
CCC
>Mature Secondary Structure
MDKGVPYRNTQYGSTVNAGAAGVGAPGAADAGGGAPSGDAAVRPDRDRLVTSHRAVLVVA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LTALCLIVLDIGTKLLAVAQLTGRAPIEIIPGVLDLRLTRNSGAAFSLAGGATVILSLIA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCEEEEEECCCCCEEEECCHHHHHHHHHH
LAVVAVVVVTARRLASIGWAFVFGAMVGGALGNLIDRLFRAPGPLRGHVVDFVHIHHWPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEECCCCC
FNVADSAIVCGGVLAVILSLRGIGLDGTRLSAAPPPDPGSAEPAGPSGPAGPSHAGGPGP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GGA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]