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The map label for this gene is sigW [H]

Identifier: 158316701

GI number: 158316701

Start: 5929218

End: 5930243

Strand: Reverse

Name: sigW [H]

Synonym: Franean1_4939

Alternate gene names: 158316701

Gene position: 5930243-5929218 (Counterclockwise)

Preceding gene: 158316713

Following gene: 158316698

Centisome position: 66.02

GC content: 73.98

Gene sequence:

>1026_bases
ATGGGTGACGTTCCTCCCGGCGGCAGAACCGGCGGGGCTGCTCTGGCCGGGGCGGAGGCGGGTGTCGAGAATCTTCTCGA
GCCGTACCGCCGCGAGCTGACCGGCTATTGCTACCGAATGCTCGGCTCGCCGTTCGAGGCGGAGGACGCCGTGCAGGACA
CGATGATCCGCGCCTGGCGCGGAATCGACCGGTTCGAAGGCCGGGCCGCGCTGCGGTCGTGGCTGTACCGCATCGCGACG
AACGTGTGCCTGTCGATGCTCGGCGCCAGTCAGCGGCGGGCACGGCCGATGGACCTCGCCGGCCCGTCGGCGGCCGACTC
CCCGCTGCCCGCGCCGCTGCCGGAGACGGCCTGGATCGTGCCCGCGCCGGACGGCCAGGTCTACTCCAGCGCCGCCGACG
CGGCCGACCCCGCCGATCTCGCCGCCCGTCGCGAGACGATCAGGCTCGCGTTCGTCGTCGCGCTGCAGCACCTGCCGGCC
CGCCAGCGGGCGGTGCTCATCCTGCGCGAGGTGTTCGGCTGGCCGGCCGCCGAGGTCGCCGACCTGCTGGAGACCTCCGT
CGCCTCGGTCAACAGCGCCCTGCAGCGGGCGCGCGCCACGATCGCCGCGACGGAGATCTCCGACGCCGACCCGCTGCGCC
CCGCCGACGCCGAGCAGCGGGAGCTGCTCGCCCGCTATGTCGACGCGTTCGAGCGGTACGACCTCGAGTCCCTCGCGGCG
CTGCTGCACGAGGACGTCACGATGTCGATGCCGCCGCTGGGCCTGTGGCTGCGGGGCCACGCCGACGTCCGGGCATGGAT
GCTCGGTACGGGCCAGGGCTGCCGGGGCTCGCGGCTGCTGCCAACCGTGGCCAACGGCCACCCGGCCTTCGGGCAGTACC
GGCCCAGCGCCACGGGTTCCGGGCACGACCCGTGGGGCCTGGTCGTCCTGGAGATCTCGGCCGGGCGGGTCGCCGGCATC
AACACGTTCCTGGACGTCGAACGCCTCTTCCCGCTGTTCGGCCTGCCGGCCCGGTTGCCTGGCTAG

Upstream 100 bases:

>100_bases
GGTTTTGTCGGAGGTGCTGGCTAGCCTTGGTTCTGGGCGTCGGTGACCCGCGGCGGCCGATCGGGCGGTGAATCAGGAGG
GCGAATCGAGGTGACCTCTG

Downstream 100 bases:

>100_bases
TGCTGCCCGGTCAACGCCGGCCGGGCACGTCCTGTGCCTGCTGCGTCGAGGCCGGCGCGGCGGCGGGAGTGAGGCGTCCG
ACGAGCGGGGCGAGGCCGGT

Product: RNA polymerase factor sigma-70

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MGDVPPGGRTGGAALAGAEAGVENLLEPYRRELTGYCYRMLGSPFEAEDAVQDTMIRAWRGIDRFEGRAALRSWLYRIAT
NVCLSMLGASQRRARPMDLAGPSAADSPLPAPLPETAWIVPAPDGQVYSSAADAADPADLAARRETIRLAFVVALQHLPA
RQRAVLILREVFGWPAAEVADLLETSVASVNSALQRARATIAATEISDADPLRPADAEQRELLARYVDAFERYDLESLAA
LLHEDVTMSMPPLGLWLRGHADVRAWMLGTGQGCRGSRLLPTVANGHPAFGQYRPSATGSGHDPWGLVVLEISAGRVAGI
NTFLDVERLFPLFGLPARLPG

Sequences:

>Translated_341_residues
MGDVPPGGRTGGAALAGAEAGVENLLEPYRRELTGYCYRMLGSPFEAEDAVQDTMIRAWRGIDRFEGRAALRSWLYRIAT
NVCLSMLGASQRRARPMDLAGPSAADSPLPAPLPETAWIVPAPDGQVYSSAADAADPADLAARRETIRLAFVVALQHLPA
RQRAVLILREVFGWPAAEVADLLETSVASVNSALQRARATIAATEISDADPLRPADAEQRELLARYVDAFERYDLESLAA
LLHEDVTMSMPPLGLWLRGHADVRAWMLGTGQGCRGSRLLPTVANGHPAFGQYRPSATGSGHDPWGLVVLEISAGRVAGI
NTFLDVERLFPLFGLPARLPG
>Mature_340_residues
GDVPPGGRTGGAALAGAEAGVENLLEPYRRELTGYCYRMLGSPFEAEDAVQDTMIRAWRGIDRFEGRAALRSWLYRIATN
VCLSMLGASQRRARPMDLAGPSAADSPLPAPLPETAWIVPAPDGQVYSSAADAADPADLAARRETIRLAFVVALQHLPAR
QRAVLILREVFGWPAAEVADLLETSVASVNSALQRARATIAATEISDADPLRPADAEQRELLARYVDAFERYDLESLAAL
LHEDVTMSMPPLGLWLRGHADVRAWMLGTGQGCRGSRLLPTVANGHPAFGQYRPSATGSGHDPWGLVVLEISAGRVAGIN
TFLDVERLFPLFGLPARLPG

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=153, Percent_Identity=29.4117647058824, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 36669; Mature: 36538

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDVPPGGRTGGAALAGAEAGVENLLEPYRRELTGYCYRMLGSPFEAEDAVQDTMIRAWR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
GIDRFEGRAALRSWLYRIATNVCLSMLGASQRRARPMDLAGPSAADSPLPAPLPETAWIV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEE
PAPDGQVYSSAADAADPADLAARRETIRLAFVVALQHLPARQRAVLILREVFGWPAAEVA
ECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHH
DLLETSVASVNSALQRARATIAATEISDADPLRPADAEQRELLARYVDAFERYDLESLAA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHH
LLHEDVTMSMPPLGLWLRGHADVRAWMLGTGQGCRGSRLLPTVANGHPAFGQYRPSATGS
HHHHCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GHDPWGLVVLEISAGRVAGINTFLDVERLFPLFGLPARLPG
CCCCCEEEEEEECCCCEECHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GDVPPGGRTGGAALAGAEAGVENLLEPYRRELTGYCYRMLGSPFEAEDAVQDTMIRAWR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
GIDRFEGRAALRSWLYRIATNVCLSMLGASQRRARPMDLAGPSAADSPLPAPLPETAWIV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEE
PAPDGQVYSSAADAADPADLAARRETIRLAFVVALQHLPARQRAVLILREVFGWPAAEVA
ECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHH
DLLETSVASVNSALQRARATIAATEISDADPLRPADAEQRELLARYVDAFERYDLESLAA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHH
LLHEDVTMSMPPLGLWLRGHADVRAWMLGTGQGCRGSRLLPTVANGHPAFGQYRPSATGS
HHHHCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GHDPWGLVVLEISAGRVAGINTFLDVERLFPLFGLPARLPG
CCCCCEEEEEEECCCCEECHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]