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The map label for this gene is trmI [H]

Identifier: 158316647

GI number: 158316647

Start: 5858866

End: 5859942

Strand: Reverse

Name: trmI [H]

Synonym: Franean1_4884

Alternate gene names: 158316647

Gene position: 5859942-5858866 (Counterclockwise)

Preceding gene: 158316648

Following gene: 158316645

Centisome position: 65.24

GC content: 74.19

Gene sequence:

>1077_bases
ATGCCCGAGGTACCCGAGGTGCCGCGGCCGACCGGCGCGGCGCGGCGCCGCGGGACGTTCACCAAGGGCGACCGCGTCCA
GCTGACCGACCCCAAGGGCCGGCGGCACACGGTCGTCCTCGAGCCGGGCCGGCAGTTCCACACCCACCGGGGGGCGATTC
CGCACGACGACCTGCTCGGCCGGCCCGAGGGTGTCGTCGTGAGCAGCACCGGGGGCACCGACTACCTGGCACTGCGGCCG
CTGCTGGCCGACTTCGTGCTGTCGATGCCGCGCGGCGCGACCGTCGTCTACCCGAAGGACGCGGCGCAGATCGTCATGTA
CGCCGACGTCTTCCCCGGCGCGCAGGTGCTGGAGGCCGGTGCCGGTTCCGGCGCGCTGTCCTGCGCCTTGCTGCGGGCCG
TGGGCGACGGCGGCCGGCTGGTCTCCTACGAGCGGCGTCCCGACTTCGCGGAGGTCGCCCGGCGCAACATCGAGACCTTT
TTCGGCGGACCACATCCGGCTCATACACTGCATGTCGGTGATCTGGCCGAGTCGGCCGAGCGGGGCATGGACCGGGTGAT
CCTCGACATGCTCGCCCCGTGGGACGTGCTGCCCGCGGCCGCGGCGGCGCTCGTCCCCGGCGGCGTGCTGTGCGCGTACG
TCGCGACGACCACGCAGCTCTCCCGGACGGTCGAGGCGCTGCGCGAGTTCGGCTGCTTCGCGGAGCCCGCGGCGTGGGAG
ACGATGATGCGCGACTGGCACGTCGAGGGCCTCGCCGTGCGCCCCGGTCACCGCATGGTCGGGCACACCGGTTTCCTGGT
GACAGCGCGCCGGTTGGCGGACGGCGTCACTGCTCCACCGAGGCGGCGGCGCCCGGCCAAGGGCTCCTATCCGGAGCCGG
CGACCGCTCCGGAGCCGGTATCCGCCGACCGCCCGGCCGAGCAGGGCCAGCCGGCGGGAGCGGGTAGCTTGCCGGGCCTG
TACGGCCAGCCCGATCGCCAGGTCATCGCGGAGCCTCAGGCCGAGCCGGAGCTTCAGGCCGAGCCGGAGCTTCAGGCCGA
GCCTGAGCCTCGAGTCGACGCCGGCTCCGACGGCTGA

Upstream 100 bases:

>100_bases
CGCGGTCGCGTCCCGCCCGCCCCTGCCGGACCTCGCGGAGCTTCCGCCCCTGCCGGACCACGCGGACCCCGCGGCACCGG
AGATGCCCGCGGCACCGGAG

Downstream 100 bases:

>100_bases
CGCGATGCCGGTCGCGGCCGGGCGATCCGCGGAGGCGCCCGCGCGGCGGGCCCGGGCGCCGGACCCCCACGGGTGGGGGC
GCGGCGGGGGCGCCGGGGTG

Product: tRNA (adenine-N(1)-)-methyltransferase

Products: NA

Alternate protein names: tRNA(m1A58)-methyltransferase; tRNA(m1A58)MTase [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MPEVPEVPRPTGAARRRGTFTKGDRVQLTDPKGRRHTVVLEPGRQFHTHRGAIPHDDLLGRPEGVVVSSTGGTDYLALRP
LLADFVLSMPRGATVVYPKDAAQIVMYADVFPGAQVLEAGAGSGALSCALLRAVGDGGRLVSYERRPDFAEVARRNIETF
FGGPHPAHTLHVGDLAESAERGMDRVILDMLAPWDVLPAAAAALVPGGVLCAYVATTTQLSRTVEALREFGCFAEPAAWE
TMMRDWHVEGLAVRPGHRMVGHTGFLVTARRLADGVTAPPRRRRPAKGSYPEPATAPEPVSADRPAEQGQPAGAGSLPGL
YGQPDRQVIAEPQAEPELQAEPELQAEPEPRVDAGSDG

Sequences:

>Translated_358_residues
MPEVPEVPRPTGAARRRGTFTKGDRVQLTDPKGRRHTVVLEPGRQFHTHRGAIPHDDLLGRPEGVVVSSTGGTDYLALRP
LLADFVLSMPRGATVVYPKDAAQIVMYADVFPGAQVLEAGAGSGALSCALLRAVGDGGRLVSYERRPDFAEVARRNIETF
FGGPHPAHTLHVGDLAESAERGMDRVILDMLAPWDVLPAAAAALVPGGVLCAYVATTTQLSRTVEALREFGCFAEPAAWE
TMMRDWHVEGLAVRPGHRMVGHTGFLVTARRLADGVTAPPRRRRPAKGSYPEPATAPEPVSADRPAEQGQPAGAGSLPGL
YGQPDRQVIAEPQAEPELQAEPELQAEPEPRVDAGSDG
>Mature_357_residues
PEVPEVPRPTGAARRRGTFTKGDRVQLTDPKGRRHTVVLEPGRQFHTHRGAIPHDDLLGRPEGVVVSSTGGTDYLALRPL
LADFVLSMPRGATVVYPKDAAQIVMYADVFPGAQVLEAGAGSGALSCALLRAVGDGGRLVSYERRPDFAEVARRNIETFF
GGPHPAHTLHVGDLAESAERGMDRVILDMLAPWDVLPAAAAALVPGGVLCAYVATTTQLSRTVEALREFGCFAEPAAWET
MMRDWHVEGLAVRPGHRMVGHTGFLVTARRLADGVTAPPRRRRPAKGSYPEPATAPEPVSADRPAEQGQPAGAGSLPGLY
GQPDRQVIAEPQAEPELQAEPELQAEPEPRVDAGSDG

Specific function: Catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. Is required for cell growth at extreme temperatures [H]

COG id: COG2519

COG function: function code J; tRNA(1-methyladenosine) methyltransferase and related methyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. TrmI family [H]

Homologues:

Organism=Homo sapiens, GI222831587, Length=217, Percent_Identity=32.7188940092166, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI123173772, Length=278, Percent_Identity=28.7769784172662, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17509459, Length=287, Percent_Identity=26.8292682926829, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24650257, Length=208, Percent_Identity=30.2884615384615, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014816 [H]

Pfam domain/function: PF08704 GCD14 [H]

EC number: =2.1.1.36 [H]

Molecular weight: Translated: 38202; Mature: 38070

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEVPEVPRPTGAARRRGTFTKGDRVQLTDPKGRRHTVVLEPGRQFHTHRGAIPHDDLLG
CCCCCCCCCCCCCHHHCCCCCCCCEEEEECCCCCEEEEEECCCHHHHHCCCCCCCHHHCC
RPEGVVVSSTGGTDYLALRPLLADFVLSMPRGATVVYPKDAAQIVMYADVFPGAQVLEAG
CCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCHHHHHCC
AGSGALSCALLRAVGDGGRLVSYERRPDFAEVARRNIETFFGGPHPAHTLHVGDLAESAE
CCCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHH
RGMDRVILDMLAPWDVLPAAAAALVPGGVLCAYVATTTQLSRTVEALREFGCFAEPAAWE
HHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
TMMRDWHVEGLAVRPGHRMVGHTGFLVTARRLADGVTAPPRRRRPAKGSYPEPATAPEPV
HHHHHHCCCCEEECCCCHHHCCCHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCC
SADRPAEQGQPAGAGSLPGLYGQPDRQVIAEPQAEPELQAEPELQAEPEPRVDAGSDG
CCCCCHHCCCCCCCCCCCCCCCCCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PEVPEVPRPTGAARRRGTFTKGDRVQLTDPKGRRHTVVLEPGRQFHTHRGAIPHDDLLG
CCCCCCCCCCCCHHHCCCCCCCCEEEEECCCCCEEEEEECCCHHHHHCCCCCCCHHHCC
RPEGVVVSSTGGTDYLALRPLLADFVLSMPRGATVVYPKDAAQIVMYADVFPGAQVLEAG
CCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCHHHHHCC
AGSGALSCALLRAVGDGGRLVSYERRPDFAEVARRNIETFFGGPHPAHTLHVGDLAESAE
CCCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHH
RGMDRVILDMLAPWDVLPAAAAALVPGGVLCAYVATTTQLSRTVEALREFGCFAEPAAWE
HHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
TMMRDWHVEGLAVRPGHRMVGHTGFLVTARRLADGVTAPPRRRRPAKGSYPEPATAPEPV
HHHHHHCCCCEEECCCCHHHCCCHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCC
SADRPAEQGQPAGAGSLPGLYGQPDRQVIAEPQAEPELQAEPELQAEPEPRVDAGSDG
CCCCCHHCCCCCCCCCCCCCCCCCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA