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The map label for this gene is echA12 [H]

Identifier: 158316545

GI number: 158316545

Start: 5707771

End: 5708490

Strand: Reverse

Name: echA12 [H]

Synonym: Franean1_4781

Alternate gene names: 158316545

Gene position: 5708490-5707771 (Counterclockwise)

Preceding gene: 158316549

Following gene: 158316542

Centisome position: 63.55

GC content: 71.81

Gene sequence:

>720_bases
ATGACGCAAGAGGTTGTGCCGTCCTACCACCCGAACATCCGGGCGGCCCGCGACGGGTTCGTCGTGACCGTCACGATCGA
CCGGCCGGAGTCGAGGAACGCCTGCACGGGCGCCGACCTCGGCGGCACCCGCGGCGAGAGCTCCTCGAACGGGAGCGGGG
CACCGTCGCACAACCTCGACAACATGCGGGTGCTGGCCGACGTGGTGCTGGCGGTTCACGACTGTCCCGTGCCGGTCGTG
GCCAAGGTCGACGGGCTCTGCGTCGGTGCCGGCCTGGGCCTCGCGCTGGCCGCCGACCTCACCTGGTGCGCGGACACGGC
ACGGTTCTCGCTGATCTTCGCCCGGCGCGGACTCAGCCTCGACTTCGGCACGTCCTGGCTGCTTCGCCAGCGGATCGGCG
TGCACCGGGCGAAGGAGCTCGTCTACACCGCGAGGATGCTCAGCGGGGCGCAGGCGGCCGAGATCGGCTTCGTGAACGCG
GTCGTGCCCGCGGCGGGGCTCGACGCCGCGGTTCGCGAGATCGCCGGCACCATCGCGGCCGGGCCGCCGGTGGCCCTGTC
CATGACCAAGCGTGAGCTGGCCGCCGCCGGGACGTCGTCACTGGCCCAGGCCCTCGAGGTCGAGGCGCTGGCACAGACGG
TGAACGTCCACACCAGGGATATGCGGGAGGCACTTACGGCCTACGCCGAGCACCGCCCGCCCGTCTTCGAGGGACACTGA

Upstream 100 bases:

>100_bases
GCGGCCGGCCGCGCGGCGGCGGGCCTGCACGGGCACGGTTCCGGCCCGCGCGCGGGTTGTCCGGTTGACGTAGGCGTCCA
ATATCTCTAGATATATAGTC

Downstream 100 bases:

>100_bases
CCGCCCGGGGCTCCGGACAGCCTCAGCGCCGACGCCGTCCCAGCGCTGATGTCGCCTCAGTACTGATGCTGCATCAGATC
GATGACTGTTTTGGCTCCCT

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MTQEVVPSYHPNIRAARDGFVVTVTIDRPESRNACTGADLGGTRGESSSNGSGAPSHNLDNMRVLADVVLAVHDCPVPVV
AKVDGLCVGAGLGLALAADLTWCADTARFSLIFARRGLSLDFGTSWLLRQRIGVHRAKELVYTARMLSGAQAAEIGFVNA
VVPAAGLDAAVREIAGTIAAGPPVALSMTKRELAAAGTSSLAQALEVEALAQTVNVHTRDMREALTAYAEHRPPVFEGH

Sequences:

>Translated_239_residues
MTQEVVPSYHPNIRAARDGFVVTVTIDRPESRNACTGADLGGTRGESSSNGSGAPSHNLDNMRVLADVVLAVHDCPVPVV
AKVDGLCVGAGLGLALAADLTWCADTARFSLIFARRGLSLDFGTSWLLRQRIGVHRAKELVYTARMLSGAQAAEIGFVNA
VVPAAGLDAAVREIAGTIAAGPPVALSMTKRELAAAGTSSLAQALEVEALAQTVNVHTRDMREALTAYAEHRPPVFEGH
>Mature_238_residues
TQEVVPSYHPNIRAARDGFVVTVTIDRPESRNACTGADLGGTRGESSSNGSGAPSHNLDNMRVLADVVLAVHDCPVPVVA
KVDGLCVGAGLGLALAADLTWCADTARFSLIFARRGLSLDFGTSWLLRQRIGVHRAKELVYTARMLSGAQAAEIGFVNAV
VPAAGLDAAVREIAGTIAAGPPVALSMTKRELAAAGTSSLAQALEVEALAQTVNVHTRDMREALTAYAEHRPPVFEGH

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=164, Percent_Identity=33.5365853658537, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI4502327, Length=226, Percent_Identity=30.9734513274336, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI87082183, Length=219, Percent_Identity=25.1141552511416, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787660, Length=209, Percent_Identity=31.1004784688995, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788597, Length=204, Percent_Identity=29.9019607843137, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI221142681, Length=172, Percent_Identity=31.9767441860465, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787659, Length=249, Percent_Identity=25.3012048192771, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17540714, Length=174, Percent_Identity=34.4827586206897, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25145438, Length=157, Percent_Identity=30.5732484076433, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=167, Percent_Identity=28.1437125748503, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24653139, Length=209, Percent_Identity=31.5789473684211, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19920382, Length=178, Percent_Identity=29.7752808988764, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20129971, Length=159, Percent_Identity=27.0440251572327, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24653477, Length=159, Percent_Identity=27.0440251572327, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19922422, Length=172, Percent_Identity=29.0697674418605, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 25005; Mature: 24874

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQEVVPSYHPNIRAARDGFVVTVTIDRPESRNACTGADLGGTRGESSSNGSGAPSHNLD
CCCCCCCCCCCCCEECCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NMRVLADVVLAVHDCPVPVVAKVDGLCVGAGLGLALAADLTWCADTARFSLIFARRGLSL
HHHHHHHHHHHHHCCCCCCEECCCCEEEECCCHHHHHHHHHHHHHHHHHEEEEECCCCCC
DFGTSWLLRQRIGVHRAKELVYTARMLSGAQAAEIGFVNAVVPAAGLDAAVREIAGTIAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
GPPVALSMTKRELAAAGTSSLAQALEVEALAQTVNVHTRDMREALTAYAEHRPPVFEGH
CCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TQEVVPSYHPNIRAARDGFVVTVTIDRPESRNACTGADLGGTRGESSSNGSGAPSHNLD
CCCCCCCCCCCCEECCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NMRVLADVVLAVHDCPVPVVAKVDGLCVGAGLGLALAADLTWCADTARFSLIFARRGLSL
HHHHHHHHHHHHHCCCCCCEECCCCEEEECCCHHHHHHHHHHHHHHHHHEEEEECCCCCC
DFGTSWLLRQRIGVHRAKELVYTARMLSGAQAAEIGFVNAVVPAAGLDAAVREIAGTIAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
GPPVALSMTKRELAAAGTSSLAQALEVEALAQTVNVHTRDMREALTAYAEHRPPVFEGH
CCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]