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The map label for this gene is hsaD [H]

Identifier: 158316513

GI number: 158316513

Start: 5670201

End: 5671088

Strand: Reverse

Name: hsaD [H]

Synonym: Franean1_4748

Alternate gene names: 158316513

Gene position: 5671088-5670201 (Counterclockwise)

Preceding gene: 158316514

Following gene: 158316512

Centisome position: 63.14

GC content: 69.71

Gene sequence:

>888_bases
GTGACCGAGGGATGGGCCAGACGCGTGTCGGAGTTCGAAAGCATCTGGAGTGACCTTCAAGGTGTCCCGTTCTCGCAGGG
ATACCTGGACGCCGCGGGCGTGCGGACGAGATATCTGCACGCCGGCGACAAGAGCCGACCGGTGCTCGTCCTGTTACATG
GTTCGGGCGGGCATGCCGAGGCCTACGTCCGCAATCTGGAGGCCCACGCACAACATTTCTCGACGTGGGCGATCGACATG
CTCGGGCACGGGTACACCGGCCGGCCCGGTCACCCCCTGGAGGTCGCCCACTACGTGGAGCACCTGATGGCGGTGCTCGA
CACCATCGGCGCGGACCGCGCCCACATCAGCGGCGAGTCCCTCGGGGGCTGGGTCGCGGCCCGCACGGCCGTCGACCATC
CGGACCGGGTCGATCGGCTGGTGCTCAACACCGCCGGCGGGTCGCAGGCGGATCCGGCCGTCATGGCGCGTATCCGCACG
CTGTCGATGGCGGCGGTGGAGGACCCGGCCTGGCCGGTCGTCCAGGCCCGGATCAAGTGGCTGATGGCGGACAAGACCCG
GGACTACGACGACCTCGTCGCGAGCCGGCAGCGCGTCTACCGGCAGTCCGGCTTCACCGCGGCGATGAGCGACATCATGG
CGCTGCAGGATCCGGCGATCAGGGCGCGTAACCTGCTCGGCCCGGCCGAGTACGGCGCCATCACCGCACCCACGCTGGTG
CTGTGGACGAGCGACGACCCGACCGCGAACGTCGCGGAGGGCAGCCGGATCGCCTCGATGATCCCGGGCGCCCGCTTCGA
GGTGATGCCCGGCTGCGGCCACTGGCCCCAGTACGAGGACGCCAAGACCTTCAACCGCCTGCACGTCGACTTCCTGCTGG
GGCGCTGA

Upstream 100 bases:

>100_bases
GTCTTGACACCCTTGAGGGCGGATCCTACTGTGCATATTTAGAACACTATCGTTCTATAGTTCGTACAGCGCTAGCGAGG
GTTGCTGGCGAGGGTGCAGC

Downstream 100 bases:

>100_bases
CCATGGCCACGGACCTGCCCGGAGCCGGCACCGCACCCGGAGCCGTCGCCGCCGCGCCGGCCGTCGTGCTGATCGGCGCC
GGCCCGGTGGGGCTGACGCT

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; HOPDA hydrolase; Meta-cleavage product hydrolase; MCP hydrolase [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTEGWARRVSEFESIWSDLQGVPFSQGYLDAAGVRTRYLHAGDKSRPVLVLLHGSGGHAEAYVRNLEAHAQHFSTWAIDM
LGHGYTGRPGHPLEVAHYVEHLMAVLDTIGADRAHISGESLGGWVAARTAVDHPDRVDRLVLNTAGGSQADPAVMARIRT
LSMAAVEDPAWPVVQARIKWLMADKTRDYDDLVASRQRVYRQSGFTAAMSDIMALQDPAIRARNLLGPAEYGAITAPTLV
LWTSDDPTANVAEGSRIASMIPGARFEVMPGCGHWPQYEDAKTFNRLHVDFLLGR

Sequences:

>Translated_295_residues
MTEGWARRVSEFESIWSDLQGVPFSQGYLDAAGVRTRYLHAGDKSRPVLVLLHGSGGHAEAYVRNLEAHAQHFSTWAIDM
LGHGYTGRPGHPLEVAHYVEHLMAVLDTIGADRAHISGESLGGWVAARTAVDHPDRVDRLVLNTAGGSQADPAVMARIRT
LSMAAVEDPAWPVVQARIKWLMADKTRDYDDLVASRQRVYRQSGFTAAMSDIMALQDPAIRARNLLGPAEYGAITAPTLV
LWTSDDPTANVAEGSRIASMIPGARFEVMPGCGHWPQYEDAKTFNRLHVDFLLGR
>Mature_294_residues
TEGWARRVSEFESIWSDLQGVPFSQGYLDAAGVRTRYLHAGDKSRPVLVLLHGSGGHAEAYVRNLEAHAQHFSTWAIDML
GHGYTGRPGHPLEVAHYVEHLMAVLDTIGADRAHISGESLGGWVAARTAVDHPDRVDRLVLNTAGGSQADPAVMARIRTL
SMAAVEDPAWPVVQARIKWLMADKTRDYDDLVASRQRVYRQSGFTAAMSDIMALQDPAIRARNLLGPAEYGAITAPTLVL
WTSDDPTANVAEGSRIASMIPGARFEVMPGCGHWPQYEDAKTFNRLHVDFLLGR

Specific function: Catalyzes the hydrolysis of a carbon-carbon bond in 4,5- 9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oic acid (4,9-DSHA) to yield 9,17-dioxo-1,2,3,4,10,19- hexanorandrostan-5-oic acid (DOHNAA) and 2-hydroxy-hexa-2,4- dienoic acid (HHD). Al

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HsaD family [H]

Homologues:

Organism=Escherichia coli, GI87081721, Length=279, Percent_Identity=25.4480286738351, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.7.1.8 [H]

Molecular weight: Translated: 32348; Mature: 32217

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEGWARRVSEFESIWSDLQGVPFSQGYLDAAGVRTRYLHAGDKSRPVLVLLHGSGGHAE
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCHH
AYVRNLEAHAQHFSTWAIDMLGHGYTGRPGHPLEVAHYVEHLMAVLDTIGADRAHISGES
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LGGWVAARTAVDHPDRVDRLVLNTAGGSQADPAVMARIRTLSMAAVEDPAWPVVQARIKW
CCCHHHECCCCCCCHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LMADKTRDYDDLVASRQRVYRQSGFTAAMSDIMALQDPAIRARNLLGPAEYGAITAPTLV
HHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHCCCCHHCCCEECCEEE
LWTSDDPTANVAEGSRIASMIPGARFEVMPGCGHWPQYEDAKTFNRLHVDFLLGR
EECCCCCCCCCCCCHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHEEEEEEECC
>Mature Secondary Structure 
TEGWARRVSEFESIWSDLQGVPFSQGYLDAAGVRTRYLHAGDKSRPVLVLLHGSGGHAE
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCHH
AYVRNLEAHAQHFSTWAIDMLGHGYTGRPGHPLEVAHYVEHLMAVLDTIGADRAHISGES
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LGGWVAARTAVDHPDRVDRLVLNTAGGSQADPAVMARIRTLSMAAVEDPAWPVVQARIKW
CCCHHHECCCCCCCHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LMADKTRDYDDLVASRQRVYRQSGFTAAMSDIMALQDPAIRARNLLGPAEYGAITAPTLV
HHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHCCCCHHCCCEECCEEE
LWTSDDPTANVAEGSRIASMIPGARFEVMPGCGHWPQYEDAKTFNRLHVDFLLGR
EECCCCCCCCCCCCHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA