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The map label for this gene is yrpG [H]

Identifier: 158316381

GI number: 158316381

Start: 5496797

End: 5497819

Strand: Reverse

Name: yrpG [H]

Synonym: Franean1_4612

Alternate gene names: 158316381

Gene position: 5497819-5496797 (Counterclockwise)

Preceding gene: 158316382

Following gene: 158316380

Centisome position: 61.21

GC content: 70.28

Gene sequence:

>1023_bases
ATGGACTACCGCGTACTTGGCCGCACCGGCGTGCGGGTCTCCCCGCTCTGCCTGGGTGCGATGATGTTCGGGACCTGGGG
CAACCAGGACCATGACGACTCAATAAAGATCATTCACAGGGCGTTGGACGCCGGCGTCAACTTCGTCGACACCGCGGATG
TCTACTCCGCCGGCGAGTCCGAGGAGATCGTCGGTAAGGCGCTGGCCGGCCGCCGCGACGACGTCGTGCTCGCAACCAAG
CTGTACATGCCGATGGGACCGGGGCCCAACCGGCGCGGCCTGTCACGGCGCTGGATCGTCACCGAGGTGGAGAACAGCCT
GCGGCGGCTCGGCACCGACTGGATCGACCTCTATCAGGTGCATCGTCCCGACCCGTCGACCGACATCGACGAGACGCTCG
GCGCGCTCACCGACCTCGTCCGGGCCGGCAAGATCCGCTACTTCGGCAGCTCGACGTTCCCGGCGCACGAGGTGGTCGAG
GCACAGTGGGTGGCCGAGCGCCGCAACCGCGAGCGGTTCGTCACCGAGCAGCCGCCGTACTCGCTGCTCGTCCGTGGGAT
CGAGGCCGACCTGCTGCCCGTGGCGCAGAAGTACGGACTCGGGGTGCTGCCGTGGAGCCCGCTGGCCGGCGGCTTCCTGT
CCGGGCGCCACACCCGCGACGGCGGCGAGGTCACGAGCACCCGGATGTCCCGGGTGCCGAACCGGTTCGATCTGTCCGTG
CCCGCGAACCAGCGCAAGGTCGAGGCCGCGATCGCGTTCGCCGACCTCGCCGCCGAGGTGGGCGTCACGCTGATCGAGCT
GGCGCTGGCGTTCGTGCTGCGCCACCCGGCGGTGACGTCGGCGATCATCGGCCCGCGCACGATGGAGCACCTGGAAAGCC
AGCTCACCGGCGGCGCCGTCACCCTGGACGAGGCGACGCTGGACCGGATCGACGAGATCGTCCCGCCTGGCGTCAACGTC
AACCCGGAGGACGCCGGGTATGTCCCGCCGTCCCTGGCCCAGCCCGCGCTCCGCCGGCGCTGA

Upstream 100 bases:

>100_bases
CCGGCCGAACATCGCCATCTGCCCACGCGCCCCCTCCAGTACGCAACAGCCTGATGTAGGGATTGCGCCAGGTTGCTCAC
CCCGCACATGCTTACCGCAC

Downstream 100 bases:

>100_bases
CCCTCACGTTCGTTCGCGGCGTCCAGAGGTCCGGGATGTTTCCAGGTCTCTGGACGCCGCGGAGTAGGGGAGAGCCGCTA
CTGCAACGGCACCTGTGTGT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MDYRVLGRTGVRVSPLCLGAMMFGTWGNQDHDDSIKIIHRALDAGVNFVDTADVYSAGESEEIVGKALAGRRDDVVLATK
LYMPMGPGPNRRGLSRRWIVTEVENSLRRLGTDWIDLYQVHRPDPSTDIDETLGALTDLVRAGKIRYFGSSTFPAHEVVE
AQWVAERRNRERFVTEQPPYSLLVRGIEADLLPVAQKYGLGVLPWSPLAGGFLSGRHTRDGGEVTSTRMSRVPNRFDLSV
PANQRKVEAAIAFADLAAEVGVTLIELALAFVLRHPAVTSAIIGPRTMEHLESQLTGGAVTLDEATLDRIDEIVPPGVNV
NPEDAGYVPPSLAQPALRRR

Sequences:

>Translated_340_residues
MDYRVLGRTGVRVSPLCLGAMMFGTWGNQDHDDSIKIIHRALDAGVNFVDTADVYSAGESEEIVGKALAGRRDDVVLATK
LYMPMGPGPNRRGLSRRWIVTEVENSLRRLGTDWIDLYQVHRPDPSTDIDETLGALTDLVRAGKIRYFGSSTFPAHEVVE
AQWVAERRNRERFVTEQPPYSLLVRGIEADLLPVAQKYGLGVLPWSPLAGGFLSGRHTRDGGEVTSTRMSRVPNRFDLSV
PANQRKVEAAIAFADLAAEVGVTLIELALAFVLRHPAVTSAIIGPRTMEHLESQLTGGAVTLDEATLDRIDEIVPPGVNV
NPEDAGYVPPSLAQPALRRR
>Mature_340_residues
MDYRVLGRTGVRVSPLCLGAMMFGTWGNQDHDDSIKIIHRALDAGVNFVDTADVYSAGESEEIVGKALAGRRDDVVLATK
LYMPMGPGPNRRGLSRRWIVTEVENSLRRLGTDWIDLYQVHRPDPSTDIDETLGALTDLVRAGKIRYFGSSTFPAHEVVE
AQWVAERRNRERFVTEQPPYSLLVRGIEADLLPVAQKYGLGVLPWSPLAGGFLSGRHTRDGGEVTSTRMSRVPNRFDLSV
PANQRKVEAAIAFADLAAEVGVTLIELALAFVLRHPAVTSAIIGPRTMEHLESQLTGGAVTLDEATLDRIDEIVPPGVNV
NPEDAGYVPPSLAQPALRRR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=319, Percent_Identity=35.1097178683386, Blast_Score=168, Evalue=7e-42,
Organism=Homo sapiens, GI27436962, Length=319, Percent_Identity=35.1097178683386, Blast_Score=168, Evalue=7e-42,
Organism=Homo sapiens, GI27436966, Length=319, Percent_Identity=34.7962382445141, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI27436969, Length=326, Percent_Identity=33.4355828220859, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI4504825, Length=324, Percent_Identity=33.3333333333333, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI27436971, Length=330, Percent_Identity=32.1212121212121, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI223718702, Length=311, Percent_Identity=29.903536977492, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI41152114, Length=311, Percent_Identity=29.903536977492, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI41327764, Length=287, Percent_Identity=29.616724738676, Blast_Score=85, Evalue=9e-17,
Organism=Escherichia coli, GI87081735, Length=310, Percent_Identity=40.9677419354839, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1789199, Length=346, Percent_Identity=31.7919075144509, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1789375, Length=334, Percent_Identity=29.6407185628743, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1788070, Length=321, Percent_Identity=31.1526479750779, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788081, Length=274, Percent_Identity=29.9270072992701, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1787674, Length=320, Percent_Identity=25.625, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994888, Length=151, Percent_Identity=33.112582781457, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI212645785, Length=313, Percent_Identity=24.9201277955272, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325169, Length=340, Percent_Identity=33.2352941176471, Blast_Score=173, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6323998, Length=332, Percent_Identity=30.7228915662651, Blast_Score=146, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6319958, Length=302, Percent_Identity=27.4834437086093, Blast_Score=129, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6319951, Length=332, Percent_Identity=26.5060240963855, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6322615, Length=277, Percent_Identity=28.158844765343, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321052, Length=156, Percent_Identity=35.2564102564103, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24640980, Length=361, Percent_Identity=24.3767313019391, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI45549126, Length=316, Percent_Identity=25.3164556962025, Blast_Score=104, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24646155, Length=310, Percent_Identity=28.3870967741935, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24646159, Length=226, Percent_Identity=33.1858407079646, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37267; Mature: 37267

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYRVLGRTGVRVSPLCLGAMMFGTWGNQDHDDSIKIIHRALDAGVNFVDTADVYSAGES
CCEEEECCCCCEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEECHHHHCCCCH
EEIVGKALAGRRDDVVLATKLYMPMGPGPNRRGLSRRWIVTEVENSLRRLGTDWIDLYQV
HHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHH
HRPDPSTDIDETLGALTDLVRAGKIRYFGSSTFPAHEVVEAQWVAERRNRERFVTEQPPY
CCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHCHHCCCCCCCCH
SLLVRGIEADLLPVAQKYGLGVLPWSPLAGGFLSGRHTRDGGEVTSTRMSRVPNRFDLSV
HHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHCCCCEEECC
PANQRKVEAAIAFADLAAEVGVTLIELALAFVLRHPAVTSAIIGPRTMEHLESQLTGGAV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHCCCEE
TLDEATLDRIDEIVPPGVNVNPEDAGYVPPSLAQPALRRR
EECHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCHHHHCC
>Mature Secondary Structure
MDYRVLGRTGVRVSPLCLGAMMFGTWGNQDHDDSIKIIHRALDAGVNFVDTADVYSAGES
CCEEEECCCCCEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEECHHHHCCCCH
EEIVGKALAGRRDDVVLATKLYMPMGPGPNRRGLSRRWIVTEVENSLRRLGTDWIDLYQV
HHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHH
HRPDPSTDIDETLGALTDLVRAGKIRYFGSSTFPAHEVVEAQWVAERRNRERFVTEQPPY
CCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHCHHCCCCCCCCH
SLLVRGIEADLLPVAQKYGLGVLPWSPLAGGFLSGRHTRDGGEVTSTRMSRVPNRFDLSV
HHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHCCCCEEECC
PANQRKVEAAIAFADLAAEVGVTLIELALAFVLRHPAVTSAIIGPRTMEHLESQLTGGAV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHCCCEE
TLDEATLDRIDEIVPPGVNVNPEDAGYVPPSLAQPALRRR
EECHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]