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The map label for this gene is mmgC [H]

Identifier: 158316354

GI number: 158316354

Start: 5465574

End: 5466689

Strand: Reverse

Name: mmgC [H]

Synonym: Franean1_4583

Alternate gene names: 158316354

Gene position: 5466689-5465574 (Counterclockwise)

Preceding gene: 158316356

Following gene: 158316353

Centisome position: 60.86

GC content: 74.73

Gene sequence:

>1116_bases
ATGAGGCTCAGCTTCACCGCCGAGCACGAGCAGTTGCGGCGGGCCGTCCGCGATTTCCTGGCGGAGCGGTCGCCGGCGGC
CGCCGTCCGGCGACTGATGGACTCGACCGCCAACCGCGACGACGACGTGTGGACCCGGCTGGCCGGGGAGCTCGGCCTGG
TGGGCCTCGGCCTGCCCGAGCAGTACGGCGGCTCCGGCTTCGGCGAGATCGAGGTCGGGATCGTGCTGGAGGAGATGGGC
CGGGCGCTGCTCGTGGCCCCCTACCTGAGCACCGCCGTGCTCGCGGGTCAGACCCTGGCGACGTCCGAGGACCGGGAGGC
GCAGCAGCGGTGGCTGCCGGGGATCGCGGCCGGCTCGCTGACCGCGACGCTGGCGGTCGCCGACGAGTCGGGATCGTGGG
AGCTGACCGACCCGGCGACGAGCGCCGAGCCGCGCGGCGGGCAGTGGCTGGTCTCCGGCCCGAACCACTACGTCCTCGAC
GGCCACAGCGCCGACCTGCTCCTGGTGGTGGCGCGGGCCGCGGACGGGACGGGGGTGTTCGCGGTCGAGGGGACGGGCCC
CGGGGCCGTGCGCGCCAGGCTCGACAGCCTCGACCCCACCCGGGACCTCGCCTCGGTCGTCCTACGGGAGGCGCCCGCGG
TCCGGGTCGGCGCGGGCCGGGAGGCGACAACGTGGCTGGGCGAGGTCCACGACCGGGCACTCGCGGCCCTGGCGTCGGAA
CAGGTCGGCGGCGCGGCGCGGTGCCTGGAGCTCGCCGTCGACTACGCGAAGGTACGGGAGCAGTTCGGCCGGCCGATCGG
CTCGTTCCAGGCGATCAAGCACAAGTGCGCCGCCCTGCTCGTCGAGGTCGAGAGCGCCCGCTCGGCGGTCTACCACGCCA
ACGCCGCACTGGCCGCCGACGACCCGGAGGGGACGGTCGCCGCGGCGGTCGCGTCGGCGTACGCATCGCGGGCGTTCACC
CTCGCCGCCAAGGAGTGCATCCAGATCCACGGCGGCATCGGGTTCACGTGGGAGCACGACGCGCACCTCTTCCTGCGGCG
GGCGAAGTCCTCCGAGCTGTTCTTCGGGGCACCGCGGGCGCAGCGCAATCGGCTCGCGGACCTGGTCGGGATCTGA

Upstream 100 bases:

>100_bases
CCCTCTTCCGTTGTCCGTCGATCCCCGCGACCGCAGCTTACAGTTGAACAATTAAACTGAAATAGTTATATTGCGCCAGA
GGGTAGAGGGAGGGCAGCTC

Downstream 100 bases:

>100_bases
GCGGTGACGATGACGCCAGCAGGCTCCGACCGGTCCGACCGGACCGCCGCCGAGACCACCAGCGAGACGACCACCGGCCC
CGCGGCCGAGACCCGCACCG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MRLSFTAEHEQLRRAVRDFLAERSPAAAVRRLMDSTANRDDDVWTRLAGELGLVGLGLPEQYGGSGFGEIEVGIVLEEMG
RALLVAPYLSTAVLAGQTLATSEDREAQQRWLPGIAAGSLTATLAVADESGSWELTDPATSAEPRGGQWLVSGPNHYVLD
GHSADLLLVVARAADGTGVFAVEGTGPGAVRARLDSLDPTRDLASVVLREAPAVRVGAGREATTWLGEVHDRALAALASE
QVGGAARCLELAVDYAKVREQFGRPIGSFQAIKHKCAALLVEVESARSAVYHANAALAADDPEGTVAAAVASAYASRAFT
LAAKECIQIHGGIGFTWEHDAHLFLRRAKSSELFFGAPRAQRNRLADLVGI

Sequences:

>Translated_371_residues
MRLSFTAEHEQLRRAVRDFLAERSPAAAVRRLMDSTANRDDDVWTRLAGELGLVGLGLPEQYGGSGFGEIEVGIVLEEMG
RALLVAPYLSTAVLAGQTLATSEDREAQQRWLPGIAAGSLTATLAVADESGSWELTDPATSAEPRGGQWLVSGPNHYVLD
GHSADLLLVVARAADGTGVFAVEGTGPGAVRARLDSLDPTRDLASVVLREAPAVRVGAGREATTWLGEVHDRALAALASE
QVGGAARCLELAVDYAKVREQFGRPIGSFQAIKHKCAALLVEVESARSAVYHANAALAADDPEGTVAAAVASAYASRAFT
LAAKECIQIHGGIGFTWEHDAHLFLRRAKSSELFFGAPRAQRNRLADLVGI
>Mature_371_residues
MRLSFTAEHEQLRRAVRDFLAERSPAAAVRRLMDSTANRDDDVWTRLAGELGLVGLGLPEQYGGSGFGEIEVGIVLEEMG
RALLVAPYLSTAVLAGQTLATSEDREAQQRWLPGIAAGSLTATLAVADESGSWELTDPATSAEPRGGQWLVSGPNHYVLD
GHSADLLLVVARAADGTGVFAVEGTGPGAVRARLDSLDPTRDLASVVLREAPAVRVGAGREATTWLGEVHDRALAALASE
QVGGAARCLELAVDYAKVREQFGRPIGSFQAIKHKCAALLVEVESARSAVYHANAALAADDPEGTVAAAVASAYASRAFT
LAAKECIQIHGGIGFTWEHDAHLFLRRAKSSELFFGAPRAQRNRLADLVGI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=373, Percent_Identity=27.3458445040214, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI226958414, Length=336, Percent_Identity=27.9761904761905, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4501857, Length=353, Percent_Identity=24.0793201133144, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI4501859, Length=386, Percent_Identity=25.6476683937824, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI4557233, Length=376, Percent_Identity=25.531914893617, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI4557231, Length=377, Percent_Identity=25.1989389920424, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI187960098, Length=377, Percent_Identity=25.1989389920424, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI7656849, Length=375, Percent_Identity=21.6, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI21361497, Length=391, Percent_Identity=24.8081841432225, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4557235, Length=347, Percent_Identity=24.7838616714697, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI76496475, Length=353, Percent_Identity=24.6458923512748, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI87081958, Length=384, Percent_Identity=24.21875, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786223, Length=367, Percent_Identity=24.5231607629428, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17570075, Length=384, Percent_Identity=26.5625, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17506239, Length=354, Percent_Identity=27.683615819209, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17508101, Length=364, Percent_Identity=26.6483516483516, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17538396, Length=366, Percent_Identity=26.5027322404372, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17534899, Length=341, Percent_Identity=26.099706744868, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17569725, Length=349, Percent_Identity=26.0744985673352, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17533517, Length=345, Percent_Identity=24.3478260869565, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=259, Percent_Identity=24.3243243243243, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=26.6666666666667, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24646207, Length=380, Percent_Identity=27.6315789473684, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21355753, Length=373, Percent_Identity=26.5415549597855, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24666513, Length=391, Percent_Identity=24.2966751918159, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24660351, Length=375, Percent_Identity=24, Blast_Score=92, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 39225; Mature: 39225

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSFTAEHEQLRRAVRDFLAERSPAAAVRRLMDSTANRDDDVWTRLAGELGLVGLGLPE
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEECCCCH
QYGGSGFGEIEVGIVLEEMGRALLVAPYLSTAVLAGQTLATSEDREAQQRWLPGIAAGSL
HHCCCCCCCEEEEEEHHHCCCEEEEHHHHHHHHHCCCHHCCCCHHHHHHHHCCCCCCCCE
TATLAVADESGSWELTDPATSAEPRGGQWLVSGPNHYVLDGHSADLLLVVARAADGTGVF
EEEEEEECCCCCEEECCCCCCCCCCCCEEEEECCCEEEECCCCCCEEEEEEECCCCCEEE
AVEGTGPGAVRARLDSLDPTRDLASVVLREAPAVRVGAGREATTWLGEVHDRALAALASE
EEECCCCCHHHHHHCCCCCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHH
QVGGAARCLELAVDYAKVREQFGRPIGSFQAIKHKCAALLVEVESARSAVYHANAALAAD
HCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCEEECC
DPEGTVAAAVASAYASRAFTLAAKECIQIHGGIGFTWEHDAHLFLRRAKSSELFFGAPRA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHCCCCCEEEECCHH
QRNRLADLVGI
HHHHHHHHHCC
>Mature Secondary Structure
MRLSFTAEHEQLRRAVRDFLAERSPAAAVRRLMDSTANRDDDVWTRLAGELGLVGLGLPE
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEECCCCH
QYGGSGFGEIEVGIVLEEMGRALLVAPYLSTAVLAGQTLATSEDREAQQRWLPGIAAGSL
HHCCCCCCCEEEEEEHHHCCCEEEEHHHHHHHHHCCCHHCCCCHHHHHHHHCCCCCCCCE
TATLAVADESGSWELTDPATSAEPRGGQWLVSGPNHYVLDGHSADLLLVVARAADGTGVF
EEEEEEECCCCCEEECCCCCCCCCCCCEEEEECCCEEEECCCCCCEEEEEEECCCCCEEE
AVEGTGPGAVRARLDSLDPTRDLASVVLREAPAVRVGAGREATTWLGEVHDRALAALASE
EEECCCCCHHHHHHCCCCCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHH
QVGGAARCLELAVDYAKVREQFGRPIGSFQAIKHKCAALLVEVESARSAVYHANAALAAD
HCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCEEECC
DPEGTVAAAVASAYASRAFTLAAKECIQIHGGIGFTWEHDAHLFLRRAKSSELFFGAPRA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHCCCCCEEEECCHH
QRNRLADLVGI
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]