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The map label for this gene is mmgC [H]

Identifier: 158316346

GI number: 158316346

Start: 5457714

End: 5458868

Strand: Reverse

Name: mmgC [H]

Synonym: Franean1_4575

Alternate gene names: 158316346

Gene position: 5458868-5457714 (Counterclockwise)

Preceding gene: 158316347

Following gene: 158316344

Centisome position: 60.78

GC content: 71.26

Gene sequence:

>1155_bases
ATGTCGACGGTTCTCCTCGGTGACGAGGAACGCGCCTTGCGCGACTCGGTCCGGTCGTTCCTCGACAAGGTGGTCGCGCC
GGAGGTCGGGGAGCACGAGCGGGCGCGCACCTTCCCGTGGGAGCTACTGCCGCAGCTCTACGACTTCGGCTACGTCCGCG
GCGGGGTGCCCGAGCCGCTCGGCGGCGACGAGCTGCCGATGATGATGCAGGCGATCCTCATGGAGGAGGCCGGCCGCTGC
TGGGGTTCACTGCGCACCACCGTGAACGTCCAGGGCATGGTGGCCCGGACGCTGGCCGCCGCGGCCAGCGAGGACCAGCG
GGCGCGGTTCCTGCAGCCGCTGCTGGCCGGGAGCCGCTTCGGCTGGTTCGGGCTCACCGAGCCCGGCGCCGGGTCCGACG
CCGGGGCGCTGCGCACGACCGCGCGCGCCAGCAGCGACGGCTATGTGGTCAACGGCAGCAAGCTCTACATCACCAACGCG
CTGGGCTGCGACTTCGGCATCCTGTTCGCCCGGGTGATCGACCACGACGGGACCGATCACGGGGTGAGCGCGCTGCTGGT
CGACGCCGCCGAGTCCGAGTTCGGCGTGCACGACATCCCGCACATGCCGTTGCGCTCGACGACCAGCTGCGAGCTGTCCT
TCCACGACACCTTCGTTCCCGCGGCCAACGTGCTCGGCACGCTGGGCGGCGGGCTGTCGCTGGGCATGAAGGCGGTGAAC
GCGGGCCGGCTGAACATGGCGATGGGCGCGGTCGGCCTGTCCCAGGCCTGCCTCGAGGCGTCGATCGCGTTCTGCCGGCA
ACGGGAGCAGTTCGGCAAGCCGATCGCCGCCTTCCAGCTCATCCAGCAGATGGTGGTGGAGATCGCCACGCTCACCGAGA
CCTCACGGCTGCTGGGGTACAACGCCGCGCGGGCCATCGACGCCGGCGAGCCGGGTCGCTACGAGTGCTCGATGGCGAAG
TACTACTGCGGGGAGTCGGCGGGCCGGGCGGCCACGCTGGCCCTGCAGGTGCACGGCGGCGCCGGGCTGATGGAGGAGTC
GCCGGTGGAGCGCTACTTCCGCGACGCGCGCGAGGCGACGATCCCGGAGGGCACCAGCCAGATCCAGATCCTGCACCTGG
GCAAGGCGCTGCTCGGTCACTCAGCCCTGCGGTGA

Upstream 100 bases:

>100_bases
GTCGAGCGGCTCAAGGAGTACGTGTCGTCGACGCTTCCCGGAACTTATCGTGATAGGTATAATGAGCTAACTAATTGATG
GCTATTGCGTGGGGTGAATG

Downstream 100 bases:

>100_bases
GCGGACCTCGTCGAGGTCGTGGACCTCGTCGGTCTGACCGGCCGGGCCGGTGGCGGCGGTGACCGCCGCGAAGGGGCGGC
CGATCCGGTCGCAGGCCAGC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSTVLLGDEERALRDSVRSFLDKVVAPEVGEHERARTFPWELLPQLYDFGYVRGGVPEPLGGDELPMMMQAILMEEAGRC
WGSLRTTVNVQGMVARTLAAAASEDQRARFLQPLLAGSRFGWFGLTEPGAGSDAGALRTTARASSDGYVVNGSKLYITNA
LGCDFGILFARVIDHDGTDHGVSALLVDAAESEFGVHDIPHMPLRSTTSCELSFHDTFVPAANVLGTLGGGLSLGMKAVN
AGRLNMAMGAVGLSQACLEASIAFCRQREQFGKPIAAFQLIQQMVVEIATLTETSRLLGYNAARAIDAGEPGRYECSMAK
YYCGESAGRAATLALQVHGGAGLMEESPVERYFRDAREATIPEGTSQIQILHLGKALLGHSALR

Sequences:

>Translated_384_residues
MSTVLLGDEERALRDSVRSFLDKVVAPEVGEHERARTFPWELLPQLYDFGYVRGGVPEPLGGDELPMMMQAILMEEAGRC
WGSLRTTVNVQGMVARTLAAAASEDQRARFLQPLLAGSRFGWFGLTEPGAGSDAGALRTTARASSDGYVVNGSKLYITNA
LGCDFGILFARVIDHDGTDHGVSALLVDAAESEFGVHDIPHMPLRSTTSCELSFHDTFVPAANVLGTLGGGLSLGMKAVN
AGRLNMAMGAVGLSQACLEASIAFCRQREQFGKPIAAFQLIQQMVVEIATLTETSRLLGYNAARAIDAGEPGRYECSMAK
YYCGESAGRAATLALQVHGGAGLMEESPVERYFRDAREATIPEGTSQIQILHLGKALLGHSALR
>Mature_383_residues
STVLLGDEERALRDSVRSFLDKVVAPEVGEHERARTFPWELLPQLYDFGYVRGGVPEPLGGDELPMMMQAILMEEAGRCW
GSLRTTVNVQGMVARTLAAAASEDQRARFLQPLLAGSRFGWFGLTEPGAGSDAGALRTTARASSDGYVVNGSKLYITNAL
GCDFGILFARVIDHDGTDHGVSALLVDAAESEFGVHDIPHMPLRSTTSCELSFHDTFVPAANVLGTLGGGLSLGMKAVNA
GRLNMAMGAVGLSQACLEASIAFCRQREQFGKPIAAFQLIQQMVVEIATLTETSRLLGYNAARAIDAGEPGRYECSMAKY
YCGESAGRAATLALQVHGGAGLMEESPVERYFRDAREATIPEGTSQIQILHLGKALLGHSALR

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=35.0267379679144, Blast_Score=221, Evalue=9e-58,
Organism=Homo sapiens, GI4557233, Length=378, Percent_Identity=33.0687830687831, Blast_Score=202, Evalue=3e-52,
Organism=Homo sapiens, GI226958412, Length=377, Percent_Identity=30.5039787798408, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI226958414, Length=340, Percent_Identity=30.2941176470588, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI4557231, Length=378, Percent_Identity=29.6296296296296, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI187960098, Length=378, Percent_Identity=29.6296296296296, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI7656849, Length=376, Percent_Identity=27.9255319148936, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI21361497, Length=368, Percent_Identity=31.25, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI4501857, Length=367, Percent_Identity=30.2452316076294, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI4557235, Length=382, Percent_Identity=30.6282722513089, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI76496475, Length=382, Percent_Identity=30.6282722513089, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI4503943, Length=396, Percent_Identity=29.040404040404, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI7669494, Length=360, Percent_Identity=29.1666666666667, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI38505218, Length=314, Percent_Identity=26.1146496815287, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI211971008, Length=297, Percent_Identity=26.9360269360269, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI48976061, Length=297, Percent_Identity=26.9360269360269, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1786223, Length=375, Percent_Identity=26.9333333333333, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI87081958, Length=374, Percent_Identity=26.4705882352941, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87082384, Length=268, Percent_Identity=26.4925373134328, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=33.0708661417323, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17534899, Length=388, Percent_Identity=32.2164948453608, Blast_Score=207, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI17508101, Length=372, Percent_Identity=32.258064516129, Blast_Score=204, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI17569725, Length=388, Percent_Identity=31.1855670103093, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17506239, Length=375, Percent_Identity=29.8666666666667, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17538396, Length=378, Percent_Identity=29.8941798941799, Blast_Score=181, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI17533517, Length=377, Percent_Identity=29.7082228116711, Blast_Score=164, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI71990804, Length=270, Percent_Identity=34.0740740740741, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI71985184, Length=386, Percent_Identity=29.5336787564767, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17505929, Length=372, Percent_Identity=30.3763440860215, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17551932, Length=373, Percent_Identity=30.0268096514745, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17534353, Length=386, Percent_Identity=27.979274611399, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI32563615, Length=235, Percent_Identity=28.0851063829787, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71982178, Length=276, Percent_Identity=26.8115942028986, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71985192, Length=315, Percent_Identity=27.9365079365079, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17531909, Length=243, Percent_Identity=29.2181069958848, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562446, Length=294, Percent_Identity=24.4897959183673, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17531913, Length=174, Percent_Identity=29.3103448275862, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI86563383, Length=327, Percent_Identity=23.8532110091743, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI86563381, Length=327, Percent_Identity=23.8532110091743, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24646207, Length=382, Percent_Identity=34.5549738219895, Blast_Score=225, Evalue=5e-59,
Organism=Drosophila melanogaster, GI21356377, Length=379, Percent_Identity=33.7730870712401, Blast_Score=219, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24666513, Length=382, Percent_Identity=31.6753926701571, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI21355753, Length=380, Percent_Identity=32.6315789473684, Blast_Score=185, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24660351, Length=380, Percent_Identity=29.2105263157895, Blast_Score=184, Evalue=7e-47,
Organism=Drosophila melanogaster, GI281363737, Length=285, Percent_Identity=32.280701754386, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI19920834, Length=389, Percent_Identity=28.5347043701799, Blast_Score=129, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 41086; Mature: 40955

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVLLGDEERALRDSVRSFLDKVVAPEVGEHERARTFPWELLPQLYDFGYVRGGVPEPL
CCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
GGDELPMMMQAILMEEAGRCWGSLRTTVNVQGMVARTLAAAASEDQRARFLQPLLAGSRF
CCCHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
GWFGLTEPGAGSDAGALRTTARASSDGYVVNGSKLYITNALGCDFGILFARVIDHDGTDH
CCCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCEEEEEECCCCCHHHHHHHHHCCCCCCC
GVSALLVDAAESEFGVHDIPHMPLRSTTSCELSFHDTFVPAANVLGTLGGGLSLGMKAVN
CHHEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHC
AGRLNMAMGAVGLSQACLEASIAFCRQREQFGKPIAAFQLIQQMVVEIATLTETSRLLGY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
NAARAIDAGEPGRYECSMAKYYCGESAGRAATLALQVHGGAGLMEESPVERYFRDAREAT
CHHHHCCCCCCCCEEHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHCC
IPEGTSQIQILHLGKALLGHSALR
CCCCCCEEEEEEHHHHHHHHHCCC
>Mature Secondary Structure 
STVLLGDEERALRDSVRSFLDKVVAPEVGEHERARTFPWELLPQLYDFGYVRGGVPEPL
CEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
GGDELPMMMQAILMEEAGRCWGSLRTTVNVQGMVARTLAAAASEDQRARFLQPLLAGSRF
CCCHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
GWFGLTEPGAGSDAGALRTTARASSDGYVVNGSKLYITNALGCDFGILFARVIDHDGTDH
CCCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCEEEEEECCCCCHHHHHHHHHCCCCCCC
GVSALLVDAAESEFGVHDIPHMPLRSTTSCELSFHDTFVPAANVLGTLGGGLSLGMKAVN
CHHEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHC
AGRLNMAMGAVGLSQACLEASIAFCRQREQFGKPIAAFQLIQQMVVEIATLTETSRLLGY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
NAARAIDAGEPGRYECSMAKYYCGESAGRAATLALQVHGGAGLMEESPVERYFRDAREAT
CHHHHCCCCCCCCEEHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHCC
IPEGTSQIQILHLGKALLGHSALR
CCCCCCEEEEEEHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]