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The map label for this gene is echA8 [H]

Identifier: 158316340

GI number: 158316340

Start: 5451949

End: 5452782

Strand: Reverse

Name: echA8 [H]

Synonym: Franean1_4569

Alternate gene names: 158316340

Gene position: 5452782-5451949 (Counterclockwise)

Preceding gene: 158316341

Following gene: 158316339

Centisome position: 60.71

GC content: 71.7

Gene sequence:

>834_bases
GTGGACGACGATGTCATGGGGAGCACGCCCCGCCCGCCCGACGGTGACTGGCTCGGCACGCCGTACCTGAGACTTGAGCG
GCACGAGCCGTTCGGGCACCTGGTCGTCGACCGGCCCGAGGCCCGCAACGCGCTCACTCCCGCGATGTACTTCGGCGTGC
GCTACGCCGTCCGGCGGGTCGACGCGGACCCGGCCCTCGCCGGCCTGCTGATCACCGGGGTCGGCGACGTGTTCATCCCC
GGCGGCGATCTGGGCAAGAACGCCGGCGACCACTGGCTGCACCTCGGCGGGGTTCCCGGGGCCATCGACGTACTTCCCTT
CGATGTCCTGCGGCAGAGCGTCAAGCCGGTGGTGGCGGCGGTGAACGGGATCTGCCAGGGCGGCGGCCTCATCATCGCGC
TGTGCTCGGACATCGCGGTGGTGAGCGAGCGGGCGACCTTCCGGGTGCCGGAGCTGCTCCGCGGGATCTCGGACACCTAC
TTCGCCTCGATGCTGGCACGCCTCGTCGGGCCGGTGCGCACGCGCGACCTGATGCTCACCGGTCGCACCCTCACAGCCCA
GGAGGCGGTCGAATGGGGCCTGGTGAGTCGGGTCGTCCCCCATGACGAACTCCTCGACGCGGCCGCTGCGGTGCTCGCCC
AGTGCTGCCAGACCGCCCCCGGCGCCCGCCGCGATGTCAAGCGCGTGCTGGACCAGTACGGCGGGCTGCACGACCGCATC
GCGTTCTTCGACAGCCTGCACCGGGACGAGTCGCGCGAGGGCTTCTCCGCCTTCATCGAGAAGCGTTCGCCCAACTGGGT
ACCCGAGGCGCTGCGCCGCGACGCCCGCGCCTGA

Upstream 100 bases:

>100_bases
AGGAGACGCTGAAGATCGTTGGGGATTGACCCCACGGCAGACGATCCGAGGTCTGTGGACGCTGGCGCCCGCCGACCGCT
GTGGCGAACGGGAGAATTCT

Downstream 100 bases:

>100_bases
CCAGGGACGGCGAGGGACGGCGAGGGACGGCGGCGGAGGGCGGTCGTGCCGGTACCGGTCGCTTGCTGGCGGCTGCGATC
TAATATAACTTAGTTATACA

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MDDDVMGSTPRPPDGDWLGTPYLRLERHEPFGHLVVDRPEARNALTPAMYFGVRYAVRRVDADPALAGLLITGVGDVFIP
GGDLGKNAGDHWLHLGGVPGAIDVLPFDVLRQSVKPVVAAVNGICQGGGLIIALCSDIAVVSERATFRVPELLRGISDTY
FASMLARLVGPVRTRDLMLTGRTLTAQEAVEWGLVSRVVPHDELLDAAAAVLAQCCQTAPGARRDVKRVLDQYGGLHDRI
AFFDSLHRDESREGFSAFIEKRSPNWVPEALRRDARA

Sequences:

>Translated_277_residues
MDDDVMGSTPRPPDGDWLGTPYLRLERHEPFGHLVVDRPEARNALTPAMYFGVRYAVRRVDADPALAGLLITGVGDVFIP
GGDLGKNAGDHWLHLGGVPGAIDVLPFDVLRQSVKPVVAAVNGICQGGGLIIALCSDIAVVSERATFRVPELLRGISDTY
FASMLARLVGPVRTRDLMLTGRTLTAQEAVEWGLVSRVVPHDELLDAAAAVLAQCCQTAPGARRDVKRVLDQYGGLHDRI
AFFDSLHRDESREGFSAFIEKRSPNWVPEALRRDARA
>Mature_277_residues
MDDDVMGSTPRPPDGDWLGTPYLRLERHEPFGHLVVDRPEARNALTPAMYFGVRYAVRRVDADPALAGLLITGVGDVFIP
GGDLGKNAGDHWLHLGGVPGAIDVLPFDVLRQSVKPVVAAVNGICQGGGLIIALCSDIAVVSERATFRVPELLRGISDTY
FASMLARLVGPVRTRDLMLTGRTLTAQEAVEWGLVSRVVPHDELLDAAAAVLAQCCQTAPGARRDVKRVLDQYGGLHDRI
AFFDSLHRDESREGFSAFIEKRSPNWVPEALRRDARA

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=252, Percent_Identity=29.3650793650794, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI31542718, Length=247, Percent_Identity=27.9352226720648, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI70995211, Length=228, Percent_Identity=29.8245614035088, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI45643119, Length=206, Percent_Identity=28.6407766990291, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI260275230, Length=206, Percent_Identity=28.6407766990291, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI260274832, Length=206, Percent_Identity=28.6407766990291, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI221142681, Length=261, Percent_Identity=32.5670498084291, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787659, Length=254, Percent_Identity=31.8897637795276, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788597, Length=256, Percent_Identity=29.296875, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87082183, Length=172, Percent_Identity=30.2325581395349, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787660, Length=253, Percent_Identity=28.8537549407115, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790281, Length=197, Percent_Identity=26.9035532994924, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788682, Length=188, Percent_Identity=30.3191489361702, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI25145438, Length=247, Percent_Identity=31.1740890688259, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17554946, Length=241, Percent_Identity=29.4605809128631, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17535521, Length=215, Percent_Identity=26.046511627907, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17536985, Length=238, Percent_Identity=25.2100840336134, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI20129971, Length=275, Percent_Identity=27.6363636363636, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24653477, Length=275, Percent_Identity=27.6363636363636, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21357171, Length=234, Percent_Identity=29.9145299145299, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19920382, Length=234, Percent_Identity=29.0598290598291, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24653139, Length=254, Percent_Identity=27.1653543307087, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 30139; Mature: 30139

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDDVMGSTPRPPDGDWLGTPYLRLERHEPFGHLVVDRPEARNALTPAMYFGVRYAVRRV
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHC
DADPALAGLLITGVGDVFIPGGDLGKNAGDHWLHLGGVPGAIDVLPFDVLRQSVKPVVAA
CCCHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEECCCCCHHHHCCHHHHHHHHHHHHHH
VNGICQGGGLIIALCSDIAVVSERATFRVPELLRGISDTYFASMLARLVGPVRTRDLMLT
HHHHCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHCCHHHHHEEEE
GRTLTAQEAVEWGLVSRVVPHDELLDAAAAVLAQCCQTAPGARRDVKRVLDQYGGLHDRI
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHH
AFFDSLHRDESREGFSAFIEKRSPNWVPEALRRDARA
HHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MDDDVMGSTPRPPDGDWLGTPYLRLERHEPFGHLVVDRPEARNALTPAMYFGVRYAVRRV
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHC
DADPALAGLLITGVGDVFIPGGDLGKNAGDHWLHLGGVPGAIDVLPFDVLRQSVKPVVAA
CCCHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEECCCCCHHHHCCHHHHHHHHHHHHHH
VNGICQGGGLIIALCSDIAVVSERATFRVPELLRGISDTYFASMLARLVGPVRTRDLMLT
HHHHCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHCCHHHHHEEEE
GRTLTAQEAVEWGLVSRVVPHDELLDAAAAVLAQCCQTAPGARRDVKRVLDQYGGLHDRI
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHH
AFFDSLHRDESREGFSAFIEKRSPNWVPEALRRDARA
HHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]