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The map label for this gene is livM [H]

Identifier: 158316261

GI number: 158316261

Start: 5351760

End: 5353745

Strand: Reverse

Name: livM [H]

Synonym: Franean1_4486

Alternate gene names: 158316261

Gene position: 5353745-5351760 (Counterclockwise)

Preceding gene: 158316262

Following gene: 158316260

Centisome position: 59.6

GC content: 69.59

Gene sequence:

>1986_bases
ATGACCGACTTTCTGCTCTACGTTCTTCTCGGTCTCGGGCCGGGCGCGGTCTACGCGGCCCTCGGTCTCGGCGTGGTGCT
GACCTACCGGAGCTCGGGGACGATCAACCTCGCCTACGGTGCCGCCGCGCTCTACCCCGCGTATGTCTTCGCACAGCTCA
ACAAGACCGGTGAGCTGATCCTCCCGATTCCCGGCGTCCCACCGATCTACTTCGGAGGCGTGCCCTCGAAGGCGGTGGCG
CTCGTGGTGGCGTTGCTCGTAGCGGCGCTGCTCGGTGTGCTGATACACCTCCTCGTGTTCCGGCCGTTGGCCACGGAGCC
CGCGCTCGCGCGGGTCGTGGCCTCCATCGGTGTGCTGATCACCATCCAAGCGATCGTGATCATCCGGTTCGACGAGCAGG
CTCTGCAGCCGGTCGGTCTCCTCCCGGACGACGCCGTCAACCTCGGTGACATCACCGTGCCCGCGGACAGGCTGCTGCTC
GGCCTGCTCGTGGTGCTCGTCTGCGCTGTGCTGGCGGCGGTCTACCGCTTCACCAGTTTCGGGCTGGCCTCCCGGGCGGC
GGCGACCAACCCGAAGGGCGCCACCCTGCTCGGTTACTCCACCGACAGCCTGGCGTTGGTCAACTCGACGATCGCGGCCG
TGCTGGCCGGCCTGTTCGGGATCCTGGTGGCGCCGATCACCAGTTTGCAGCCCACCACCCTGACCCTGTTGATCGTGCCC
GCGCTGGCCGCCGCCCTGATCGGCCGGTTCACCTCGTTCGGTGTCACCGTGGCCGCGGCCCTGGTCGTCGGCATCCTGCA
GTCGCAGATCGTGCTGCTCCAGGGCAAGCTCGAGTGGCTGCCGCGGGCCGGCCTGGGTGACGCCCTGCCGTTCGCGGTGA
TCGTGATCGCCATGTTCGCGGTGGGGGCGCGGCTTCCCGGTCGCGGCGCGGCGAGCAACGAGCGGATGCCGACCGCGCCG
CCACCGAGGCACCGATGGTCGGTGGGGCTCCCCGCCGTGGCGGTGGGCTGCGCGATCGTGTACGTCCTCAGCGACGCCTA
CCTCGGCAGCTACGTCACCTCGTTGATCGCGGGGCTGGTCTGCCTGTCATTCGTCGTGCTGACCGGCTACACGGGCCAGG
TCTCACTGGCCCAGATGGCGATCGCGGGCGTGTCGGCGTTCGGGCTGAGCAAGTTCGCCCACGGGATCGGGATTCCGTTC
CCGCTGGCGCCGCTGCTCGCCATCGGCGGCGCGGTGCTCGGCGCCCTCGCGGTCGGCATCCCGGCCCTACGGGTACGTGG
GGTGCACCTAGCCGTCGTGACGATCGCGCTGGCGGTCGCCGTCGCGTCCGCCGTCTTCGGCAACCCGGCCGTGACGGGCG
GCACGAGCGGTAGCCCGGTACCCACCCTGTCGATCTTCGGCTTCGATTTCCGCGGTGGGGAGACCGGGTTCGCGGTGGTG
ACGGTGCTGGTCCTCGCCGTTGCGGGGTTCGCGGTGGCGAACCTGCGGCTCAGCCCGGTCGGGCTGCAGATGCTCGCGGT
ACGCGCCAACGAGCGGGCGGCGGCCTCGGTCGGCATCAACGTCGCCCGCATGAAGCTGCTCGCCTTCGCGTTCTCGGGAG
TGCTCTCGGGCACGGCGGGCGTCATGCTCGCCTACAACCAGAGCAACGTGTCGTTCCAGTCGTTCGGTGCGATCGCGTCG
CTGTCGTTCCTCGCGGTGGCCTACCTGGGCGGGATCACCACGATCTCCGGCGCAGTTGTCGGCGGCATGCTGGTGAACGG
CGGGCTGATGACCCTGGCCCTGCAGAACTGGTTCGAGATCGGCTCGTACCAGTTGCTGGTGAGCGGCGTCGGTCTGATCG
TCACCGCGGTACTCAACCCGCAGGGCATCAGCGGCGCGACCCAGCAGAGTGCCGCGAAGCTCCTCGCCGCCATCCGACGG
CGGGGCCATCCGAGCCCGTCCGAACTCGGGAAACCCCCAGCCGTGCCGTCCGGAGTCGCATCATGA

Upstream 100 bases:

>100_bases
TGATCGTCGAGGTGAAGAACGGCGTTCCGACCACCATCTCGGACCCGATCGACGGCTCGAAGCTCCTGCGGCTCTGAGAC
CGGACCGAGGCTAACGACAC

Downstream 100 bases:

>100_bases
CCGCGCTGCTTGAACTGGACTCGATCGCCGTCCGGTACGGCGGGGTGGCGGCGCTCAAGGGCGTCTCGTTCACGGTGCCG
AGCAACAGCATCGTCGGGCT

Product: inner-membrane translocator

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein M [H]

Number of amino acids: Translated: 661; Mature: 660

Protein sequence:

>661_residues
MTDFLLYVLLGLGPGAVYAALGLGVVLTYRSSGTINLAYGAAALYPAYVFAQLNKTGELILPIPGVPPIYFGGVPSKAVA
LVVALLVAALLGVLIHLLVFRPLATEPALARVVASIGVLITIQAIVIIRFDEQALQPVGLLPDDAVNLGDITVPADRLLL
GLLVVLVCAVLAAVYRFTSFGLASRAAATNPKGATLLGYSTDSLALVNSTIAAVLAGLFGILVAPITSLQPTTLTLLIVP
ALAAALIGRFTSFGVTVAAALVVGILQSQIVLLQGKLEWLPRAGLGDALPFAVIVIAMFAVGARLPGRGAASNERMPTAP
PPRHRWSVGLPAVAVGCAIVYVLSDAYLGSYVTSLIAGLVCLSFVVLTGYTGQVSLAQMAIAGVSAFGLSKFAHGIGIPF
PLAPLLAIGGAVLGALAVGIPALRVRGVHLAVVTIALAVAVASAVFGNPAVTGGTSGSPVPTLSIFGFDFRGGETGFAVV
TVLVLAVAGFAVANLRLSPVGLQMLAVRANERAAASVGINVARMKLLAFAFSGVLSGTAGVMLAYNQSNVSFQSFGAIAS
LSFLAVAYLGGITTISGAVVGGMLVNGGLMTLALQNWFEIGSYQLLVSGVGLIVTAVLNPQGISGATQQSAAKLLAAIRR
RGHPSPSELGKPPAVPSGVAS

Sequences:

>Translated_661_residues
MTDFLLYVLLGLGPGAVYAALGLGVVLTYRSSGTINLAYGAAALYPAYVFAQLNKTGELILPIPGVPPIYFGGVPSKAVA
LVVALLVAALLGVLIHLLVFRPLATEPALARVVASIGVLITIQAIVIIRFDEQALQPVGLLPDDAVNLGDITVPADRLLL
GLLVVLVCAVLAAVYRFTSFGLASRAAATNPKGATLLGYSTDSLALVNSTIAAVLAGLFGILVAPITSLQPTTLTLLIVP
ALAAALIGRFTSFGVTVAAALVVGILQSQIVLLQGKLEWLPRAGLGDALPFAVIVIAMFAVGARLPGRGAASNERMPTAP
PPRHRWSVGLPAVAVGCAIVYVLSDAYLGSYVTSLIAGLVCLSFVVLTGYTGQVSLAQMAIAGVSAFGLSKFAHGIGIPF
PLAPLLAIGGAVLGALAVGIPALRVRGVHLAVVTIALAVAVASAVFGNPAVTGGTSGSPVPTLSIFGFDFRGGETGFAVV
TVLVLAVAGFAVANLRLSPVGLQMLAVRANERAAASVGINVARMKLLAFAFSGVLSGTAGVMLAYNQSNVSFQSFGAIAS
LSFLAVAYLGGITTISGAVVGGMLVNGGLMTLALQNWFEIGSYQLLVSGVGLIVTAVLNPQGISGATQQSAAKLLAAIRR
RGHPSPSELGKPPAVPSGVAS
>Mature_660_residues
TDFLLYVLLGLGPGAVYAALGLGVVLTYRSSGTINLAYGAAALYPAYVFAQLNKTGELILPIPGVPPIYFGGVPSKAVAL
VVALLVAALLGVLIHLLVFRPLATEPALARVVASIGVLITIQAIVIIRFDEQALQPVGLLPDDAVNLGDITVPADRLLLG
LLVVLVCAVLAAVYRFTSFGLASRAAATNPKGATLLGYSTDSLALVNSTIAAVLAGLFGILVAPITSLQPTTLTLLIVPA
LAAALIGRFTSFGVTVAAALVVGILQSQIVLLQGKLEWLPRAGLGDALPFAVIVIAMFAVGARLPGRGAASNERMPTAPP
PRHRWSVGLPAVAVGCAIVYVLSDAYLGSYVTSLIAGLVCLSFVVLTGYTGQVSLAQMAIAGVSAFGLSKFAHGIGIPFP
LAPLLAIGGAVLGALAVGIPALRVRGVHLAVVTIALAVAVASAVFGNPAVTGGTSGSPVPTLSIFGFDFRGGETGFAVVT
VLVLAVAGFAVANLRLSPVGLQMLAVRANERAAASVGINVARMKLLAFAFSGVLSGTAGVMLAYNQSNVSFQSFGAIASL
SFLAVAYLGGITTISGAVVGGMLVNGGLMTLALQNWFEIGSYQLLVSGVGLIVTAVLNPQGISGATQQSAAKLLAAIRRR
GHPSPSELGKPPAVPSGVAS

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789865, Length=299, Percent_Identity=27.4247491638796, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851
- InterPro:   IPR021807 [H]

Pfam domain/function: PF02653 BPD_transp_2; PF11862 DUF3382 [H]

EC number: NA

Molecular weight: Translated: 66807; Mature: 66676

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFLLYVLLGLGPGAVYAALGLGVVLTYRSSGTINLAYGAAALYPAYVFAQLNKTGELI
CHHHHHHHHHHCCCHHHHHHHHHHEEEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCEE
LPIPGVPPIYFGGVPSKAVALVVALLVAALLGVLIHLLVFRPLATEPALARVVASIGVLI
EECCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
TIQAIVIIRFDEQALQPVGLLPDDAVNLGDITVPADRLLLGLLVVLVCAVLAAVYRFTSF
EEEEHEEEEECHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GLASRAAATNPKGATLLGYSTDSLALVNSTIAAVLAGLFGILVAPITSLQPTTLTLLIVP
CHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
ALAAALIGRFTSFGVTVAAALVVGILQSQIVLLQGKLEWLPRAGLGDALPFAVIVIAMFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHCCCCCCCCHHHHHHHHHHHHH
VGARLPGRGAASNERMPTAPPPRHRWSVGLPAVAVGCAIVYVLSDAYLGSYVTSLIAGLV
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CLSFVVLTGYTGQVSLAQMAIAGVSAFGLSKFAHGIGIPFPLAPLLAIGGAVLGALAVGI
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
PALRVRGVHLAVVTIALAVAVASAVFGNPAVTGGTSGSPVPTLSIFGFDFRGGETGFAVV
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHH
TVLVLAVAGFAVANLRLSPVGLQMLAVRANERAAASVGINVARMKLLAFAFSGVLSGTAG
HHHHHHHHHHHHHCCEECCCCCEEEEEECCCHHHHHHCHHHHHHHHHHHHHHHHHCCCCC
VMLAYNQSNVSFQSFGAIASLSFLAVAYLGGITTISGAVVGGMLVNGGLMTLALQNWFEI
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
GSYQLLVSGVGLIVTAVLNPQGISGATQQSAAKLLAAIRRRGHPSPSELGKPPAVPSGVA
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCC
S
C
>Mature Secondary Structure 
TDFLLYVLLGLGPGAVYAALGLGVVLTYRSSGTINLAYGAAALYPAYVFAQLNKTGELI
HHHHHHHHHHCCCHHHHHHHHHHEEEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCEE
LPIPGVPPIYFGGVPSKAVALVVALLVAALLGVLIHLLVFRPLATEPALARVVASIGVLI
EECCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
TIQAIVIIRFDEQALQPVGLLPDDAVNLGDITVPADRLLLGLLVVLVCAVLAAVYRFTSF
EEEEHEEEEECHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GLASRAAATNPKGATLLGYSTDSLALVNSTIAAVLAGLFGILVAPITSLQPTTLTLLIVP
CHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
ALAAALIGRFTSFGVTVAAALVVGILQSQIVLLQGKLEWLPRAGLGDALPFAVIVIAMFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHCCCCCCCCHHHHHHHHHHHHH
VGARLPGRGAASNERMPTAPPPRHRWSVGLPAVAVGCAIVYVLSDAYLGSYVTSLIAGLV
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CLSFVVLTGYTGQVSLAQMAIAGVSAFGLSKFAHGIGIPFPLAPLLAIGGAVLGALAVGI
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
PALRVRGVHLAVVTIALAVAVASAVFGNPAVTGGTSGSPVPTLSIFGFDFRGGETGFAVV
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHH
TVLVLAVAGFAVANLRLSPVGLQMLAVRANERAAASVGINVARMKLLAFAFSGVLSGTAG
HHHHHHHHHHHHHCCEECCCCCEEEEEECCCHHHHHHCHHHHHHHHHHHHHHHHHCCCCC
VMLAYNQSNVSFQSFGAIASLSFLAVAYLGGITTISGAVVGGMLVNGGLMTLALQNWFEI
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
GSYQLLVSGVGLIVTAVLNPQGISGATQQSAAKLLAAIRRRGHPSPSELGKPPAVPSGVA
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2195019; 8041620; 9278503 [H]