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The map label for this gene is desK [H]

Identifier: 158316115

GI number: 158316115

Start: 5176408

End: 5177439

Strand: Reverse

Name: desK [H]

Synonym: Franean1_4333

Alternate gene names: 158316115

Gene position: 5177439-5176408 (Counterclockwise)

Preceding gene: 158316121

Following gene: 158316114

Centisome position: 57.64

GC content: 75.19

Gene sequence:

>1032_bases
ATGGCCTCGGCCAGGGTGCCGGGACCGGTGGCGCCACCGGTCGTGATCGGGCTGGCGGCCGGGGCCGTCGTGCTGCTGAT
CTGGGCGGCCGTCGGCGGTGGTTACTTCTGGCCGCGCTGGGTGTGGTTCGGCATCGGCACCGTGTTCTGGGCCGCGATCC
TCGTCGGGTGGGTCCGGCGGATACCGCCGGGGCGGCGCCGGTGGCTCGCCGCCACCCGGGCGGTGGCTGCCCTGGCCATC
CCGGTCGACGTGGTGGTGTGGGCGCTGTCCGGCGGCGGCTACTTCTGGCCGGTCTGGACGATTCTCGCGCTCACGATCGG
GCTCGCCATCCACACCTGGATCGTCGCGCTGATGCCCGCCGAGCGGGAGCGTGAGCTCACCGAGCGGGTCGACGCGCTCA
CCCGCACCCGCCGCGGCGCGCTCGACGGGCAGGCCGCCGAGCTCAAGCGGATCGAGCGGGACCTGCACGACGGCGCCCAG
GCGCGGATCGTCTCGCTGGCGATGAACCTCGGCATGGCCGAGGCCCTGCTGCACAGCGACCCGGCGGCGGCGGCGAAGCT
GCTCAGCGACGCCCGGCTGTCCGCGGTCGGCGCGCTCGACGACCTGCGGGCCGTCATGCACAGCATCCACCCCTCGGTGC
TCGCCGACCGGGGGCTCGCCGGGGGCATCCGCGCGCTCGCGCTCGACCTGTCCCTGCCGGTCCGCGTCGACGGCGACGTC
CCGTCCGGGCTGCCGGCGGCGGTCGAGTCGGCCGTCTACTTCGCGACCGCGGAATGCCTGGCCAACGTCGTCAAGCACAG
CCGGGCCGCGCACGGCACGGTGCGGTTCGCGCACGACGGCAGGATGCTGAGCGTGGTCGTCACGGACGACGGGCTCGGCG
GGGCGGATCCCGCGTTCGGCCAGGGCCTGCGCGGGGTGGTGCGCCGGCTCGAGGCGTTCGACGGCCGGATGTCGGTACAC
AGCCCGTCCGGGGGACCGACGAGGATCACGATCACCCTGCCGTGCCCGGTCCTGCCGGGCGCGGAGGCCTGA

Upstream 100 bases:

>100_bases
CGGGGGGCCAGTCCCCGGGCGAAAGGGATGCCCAGGCCTCTCGTGGTCGCCGTCCGGTTCGGCGAGGCTGGAGCACATGA
GTTCCGGGAAGGTCTCGACC

Downstream 100 bases:

>100_bases
GGGCCTGAGCGCCCAAAGGACCTGAGGACCTGAGGACCGAGCGAAACTGAGGAGGTGCCGTCCGTGCCGGAGGAACCCGC
CGACCCCGCGCGGCCGCTGC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MASARVPGPVAPPVVIGLAAGAVVLLIWAAVGGGYFWPRWVWFGIGTVFWAAILVGWVRRIPPGRRRWLAATRAVAALAI
PVDVVVWALSGGGYFWPVWTILALTIGLAIHTWIVALMPAERERELTERVDALTRTRRGALDGQAAELKRIERDLHDGAQ
ARIVSLAMNLGMAEALLHSDPAAAAKLLSDARLSAVGALDDLRAVMHSIHPSVLADRGLAGGIRALALDLSLPVRVDGDV
PSGLPAAVESAVYFATAECLANVVKHSRAAHGTVRFAHDGRMLSVVVTDDGLGGADPAFGQGLRGVVRRLEAFDGRMSVH
SPSGGPTRITITLPCPVLPGAEA

Sequences:

>Translated_343_residues
MASARVPGPVAPPVVIGLAAGAVVLLIWAAVGGGYFWPRWVWFGIGTVFWAAILVGWVRRIPPGRRRWLAATRAVAALAI
PVDVVVWALSGGGYFWPVWTILALTIGLAIHTWIVALMPAERERELTERVDALTRTRRGALDGQAAELKRIERDLHDGAQ
ARIVSLAMNLGMAEALLHSDPAAAAKLLSDARLSAVGALDDLRAVMHSIHPSVLADRGLAGGIRALALDLSLPVRVDGDV
PSGLPAAVESAVYFATAECLANVVKHSRAAHGTVRFAHDGRMLSVVVTDDGLGGADPAFGQGLRGVVRRLEAFDGRMSVH
SPSGGPTRITITLPCPVLPGAEA
>Mature_342_residues
ASARVPGPVAPPVVIGLAAGAVVLLIWAAVGGGYFWPRWVWFGIGTVFWAAILVGWVRRIPPGRRRWLAATRAVAALAIP
VDVVVWALSGGGYFWPVWTILALTIGLAIHTWIVALMPAERERELTERVDALTRTRRGALDGQAAELKRIERDLHDGAQA
RIVSLAMNLGMAEALLHSDPAAAAKLLSDARLSAVGALDDLRAVMHSIHPSVLADRGLAGGIRALALDLSLPVRVDGDVP
SGLPAAVESAVYFATAECLANVVKHSRAAHGTVRFAHDGRMLSVVVTDDGLGGADPAFGQGLRGVVRRLEAFDGRMSVHS
PSGGPTRITITLPCPVLPGAEA

Specific function: Member of the two-component regulatory system desR/desK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase. Acts as a sensor of the membrane fluidity. Probably activates desR by phosphorylation [H]

COG id: COG4564

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011712 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 36140; Mature: 36009

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASARVPGPVAPPVVIGLAAGAVVLLIWAAVGGGYFWPRWVWFGIGTVFWAAILVGWVRR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IPPGRRRWLAATRAVAALAIPVDVVVWALSGGGYFWPVWTILALTIGLAIHTWIVALMPA
CCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
ERERELTERVDALTRTRRGALDGQAAELKRIERDLHDGAQARIVSLAMNLGMAEALLHSD
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHCC
PAAAAKLLSDARLSAVGALDDLRAVMHSIHPSVLADRGLAGGIRALALDLSLPVRVDGDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHEEEECCCCEEECCCC
PSGLPAAVESAVYFATAECLANVVKHSRAAHGTVRFAHDGRMLSVVVTDDGLGGADPAFG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEEEECCCCCCCCCHHH
QGLRGVVRRLEAFDGRMSVHSPSGGPTRITITLPCPVLPGAEA
HHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
ASARVPGPVAPPVVIGLAAGAVVLLIWAAVGGGYFWPRWVWFGIGTVFWAAILVGWVRR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IPPGRRRWLAATRAVAALAIPVDVVVWALSGGGYFWPVWTILALTIGLAIHTWIVALMPA
CCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
ERERELTERVDALTRTRRGALDGQAAELKRIERDLHDGAQARIVSLAMNLGMAEALLHSD
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHCC
PAAAAKLLSDARLSAVGALDDLRAVMHSIHPSVLADRGLAGGIRALALDLSLPVRVDGDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHEEEECCCCEEECCCC
PSGLPAAVESAVYFATAECLANVVKHSRAAHGTVRFAHDGRMLSVVVTDDGLGGADPAFG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEEEECCCCCCCCCHHH
QGLRGVVRRLEAFDGRMSVHSPSGGPTRITITLPCPVLPGAEA
HHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]