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The map label for this gene is frc [H]

Identifier: 158316097

GI number: 158316097

Start: 5155178

End: 5156539

Strand: Reverse

Name: frc [H]

Synonym: Franean1_4315

Alternate gene names: 158316097

Gene position: 5156539-5155178 (Counterclockwise)

Preceding gene: 158316100

Following gene: 158316095

Centisome position: 57.41

GC content: 73.13

Gene sequence:

>1362_bases
ATGTCGGTCCTGCCGGCGATGTCGGCCGGTCGGCGCGGCCGCGCGGGGCACGCGGGTGCCCGCGCGCCGGTTCCGACGGC
GATGCCCGGGAGCCGGTGCCGTGGAGCTGGAGGCGCACGTGGAGCACGTGGAGCACGAGACGATCGCGCGGGCGGCCGCA
TGAGGCCGCTCGAGGGGGTCCGGGTTCTCGAGGTGGCGATGTACGGCTTCGTGCCGTCCGCGGGCGGGGTGCTCGCCGAC
TGGGGCGCCGAGGTCATCAAGGTCGAGCACGCCGTGACCGGCGACCCGCAGCGTGGGCTGAAGCAGACCGGCAACCTCAA
GGTCGGCGACGGGCCGAACCCGAACATCGAGCACGCGAACCGCGGCAAGCGCAGCCTCGGCCTCGACATGTCGAAGCCGG
AGGGCAAGGCGGTCCTCGAGGAGCTGATCCGGCGCGCGGACGTGTTCCTGACCAGCTTCCTGCCGCGCTCGCGCCGCAGT
CTCGGCATCGACGTCGACGACGTCCGCGCGATCAACCCGAAGATCATCTATGCGCGTGGCAGCGCGCTGGGCCCGCGCGG
CGTCGAGTCGGAGAAGGGCGGTTTCGACATGACCGCCTTCTGGGCGCGTGCCTCCTGCGCGGCCAGCATCACCCCCCGCA
GCCGCGACGGCATGACGCCGCCGCCGGGGCCGGCCTACGGCGACACGATCTCGGGCACGAACCTCGCCGGTGGGATCGCG
GCGGCCCTGTTCAGCCGGGAGCGCACCGGCGAGCCGTCCGTCGTGGACGTCTCGCTGCTGGGCAGCGGGCTGTGGGCGAT
GGGGCAGTCGATCGCCCTGTCGCTCATGCTCGACGAGCCGCTGGTGGCCCCCGAGCCCGGCTCGCTCGCCTCGCCCAACC
CGCTGTCGGCGCTGTACCGGACCTCCGACGGCCGGTTCCTCTCGCTCGTCATGCTGCAGGCCGGCCGGTACTGGCCGGAC
GTCTGCCGTCACATCGACCGGCCGGAGCTGGCCGACGACCCGCGGTTCGCCACCGCCGAGCTGATCGCGGCCAACGCCGA
GGAGGCGGTGAAGCTGCTCAGGGAGGCGTTCGCCGCCCGCACCCTGGCGGAGTGGACCGAGCGGCTGGCCACGCTCTCCG
GGCCGTGGGCCCCGGTGCAGGACTCGTTGCAGGTGGGCGGCGACGCCCAGATCCGGGCGAACGAGTACCTGCTCCCGGCC
GGGGAGATCGAGCTCGTCTCCAGCCCGGTTCAGTTCGACGTGTCCGCCCCCGAGCTCGGACCCGCCCCCGAGTTCGCCGC
CCAGACCGAGGAGATCCTCATGGAACTGGGCCTGGACTGGGACCGCATCATCGAGCTCAAGGGTGCCGGCGCGGTCACCT
GA

Upstream 100 bases:

>100_bases
GCTTGTCCCGAGAATGTAACTTTCAGTCATCCTTTCCGGGCGTCGGCAGGTGGCGGCGGTCCGTGCCTCACCCCGGCCGG
CGACGTCGGCCCTACCGGCG

Downstream 100 bases:

>100_bases
GCCCGACACACGTCGCGGGCGGCCGGCAGTCCGGCCGCCCGCGAGGGCCAGCGCCGAGGTCGGCAGGCCTGGCCGCCCGC
CAGGGCCGGCCGGCCGGTCG

Product: L-carnitine dehydratase/bile acid-inducible protein F

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MSVLPAMSAGRRGRAGHAGARAPVPTAMPGSRCRGAGGARGARGARDDRAGGRMRPLEGVRVLEVAMYGFVPSAGGVLAD
WGAEVIKVEHAVTGDPQRGLKQTGNLKVGDGPNPNIEHANRGKRSLGLDMSKPEGKAVLEELIRRADVFLTSFLPRSRRS
LGIDVDDVRAINPKIIYARGSALGPRGVESEKGGFDMTAFWARASCAASITPRSRDGMTPPPGPAYGDTISGTNLAGGIA
AALFSRERTGEPSVVDVSLLGSGLWAMGQSIALSLMLDEPLVAPEPGSLASPNPLSALYRTSDGRFLSLVMLQAGRYWPD
VCRHIDRPELADDPRFATAELIAANAEEAVKLLREAFAARTLAEWTERLATLSGPWAPVQDSLQVGGDAQIRANEYLLPA
GEIELVSSPVQFDVSAPELGPAPEFAAQTEEILMELGLDWDRIIELKGAGAVT

Sequences:

>Translated_453_residues
MSVLPAMSAGRRGRAGHAGARAPVPTAMPGSRCRGAGGARGARGARDDRAGGRMRPLEGVRVLEVAMYGFVPSAGGVLAD
WGAEVIKVEHAVTGDPQRGLKQTGNLKVGDGPNPNIEHANRGKRSLGLDMSKPEGKAVLEELIRRADVFLTSFLPRSRRS
LGIDVDDVRAINPKIIYARGSALGPRGVESEKGGFDMTAFWARASCAASITPRSRDGMTPPPGPAYGDTISGTNLAGGIA
AALFSRERTGEPSVVDVSLLGSGLWAMGQSIALSLMLDEPLVAPEPGSLASPNPLSALYRTSDGRFLSLVMLQAGRYWPD
VCRHIDRPELADDPRFATAELIAANAEEAVKLLREAFAARTLAEWTERLATLSGPWAPVQDSLQVGGDAQIRANEYLLPA
GEIELVSSPVQFDVSAPELGPAPEFAAQTEEILMELGLDWDRIIELKGAGAVT
>Mature_452_residues
SVLPAMSAGRRGRAGHAGARAPVPTAMPGSRCRGAGGARGARGARDDRAGGRMRPLEGVRVLEVAMYGFVPSAGGVLADW
GAEVIKVEHAVTGDPQRGLKQTGNLKVGDGPNPNIEHANRGKRSLGLDMSKPEGKAVLEELIRRADVFLTSFLPRSRRSL
GIDVDDVRAINPKIIYARGSALGPRGVESEKGGFDMTAFWARASCAASITPRSRDGMTPPPGPAYGDTISGTNLAGGIAA
ALFSRERTGEPSVVDVSLLGSGLWAMGQSIALSLMLDEPLVAPEPGSLASPNPLSALYRTSDGRFLSLVMLQAGRYWPDV
CRHIDRPELADDPRFATAELIAANAEEAVKLLREAFAARTLAEWTERLATLSGPWAPVQDSLQVGGDAQIRANEYLLPAG
EIELVSSPVQFDVSAPELGPAPEFAAQTEEILMELGLDWDRIIELKGAGAVT

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate. Essential enzyme for the bacterium survival, as it relies on oxalic acid as its sole source of energy [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=435, Percent_Identity=28.735632183908, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI300863124, Length=461, Percent_Identity=27.5488069414317, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI266456254, Length=417, Percent_Identity=26.378896882494, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI13376042, Length=454, Percent_Identity=25.1101321585903, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI42794625, Length=403, Percent_Identity=26.302729528536, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI266458393, Length=262, Percent_Identity=30.1526717557252, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI266458397, Length=262, Percent_Identity=30.1526717557252, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI300863126, Length=172, Percent_Identity=32.5581395348837, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI266458395, Length=142, Percent_Identity=31.6901408450704, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI42822893, Length=142, Percent_Identity=31.6901408450704, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI87082093, Length=389, Percent_Identity=23.6503856041131, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788717, Length=427, Percent_Identity=25.0585480093677, Blast_Score=99, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI115535051, Length=338, Percent_Identity=24.5562130177515, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI32564160, Length=341, Percent_Identity=23.4604105571848, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648431, Length=405, Percent_Identity=28.8888888888889, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24585488, Length=347, Percent_Identity=27.3775216138329, Blast_Score=112, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 47839; Mature: 47708

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLPAMSAGRRGRAGHAGARAPVPTAMPGSRCRGAGGARGARGARDDRAGGRMRPLEGV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCH
RVLEVAMYGFVPSAGGVLADWGAEVIKVEHAVTGDPQRGLKQTGNLKVGDGPNPNIEHAN
HHHHHHHHHCCCCCCCCHHHCCCEEEEEEHHCCCCHHHHHHHCCCEEECCCCCCCCCCCC
RGKRSLGLDMSKPEGKAVLEELIRRADVFLTSFLPRSRRSLGIDVDDVRAINPKIIYARG
CCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHEECCCEEEEEEC
SALGPRGVESEKGGFDMTAFWARASCAASITPRSRDGMTPPPGPAYGDTISGTNLAGGIA
CCCCCCCCCCCCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
AALFSRERTGEPSVVDVSLLGSGLWAMGQSIALSLMLDEPLVAPEPGSLASPNPLSALYR
HHHHHHCCCCCCCEEEHHHHHCCHHHHHHHHEEEEEECCCCCCCCCCCCCCCCHHHHHEE
TSDGRFLSLVMLQAGRYWPDVCRHIDRPELADDPRFATAELIAANAEEAVKLLREAFAAR
CCCCCEEEHHHHHCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHH
TLAEWTERLATLSGPWAPVQDSLQVGGDAQIRANEYLLPAGEIELVSSPVQFDVSAPELG
HHHHHHHHHHHCCCCCCCCCHHHHCCCCCEEECCCEECCCCCEEEECCCCEEECCCCCCC
PAPEFAAQTEEILMELGLDWDRIIELKGAGAVT
CCCHHHHHHHHHHHHHCCCHHHEEEECCCCCCC
>Mature Secondary Structure 
SVLPAMSAGRRGRAGHAGARAPVPTAMPGSRCRGAGGARGARGARDDRAGGRMRPLEGV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCH
RVLEVAMYGFVPSAGGVLADWGAEVIKVEHAVTGDPQRGLKQTGNLKVGDGPNPNIEHAN
HHHHHHHHHCCCCCCCCHHHCCCEEEEEEHHCCCCHHHHHHHCCCEEECCCCCCCCCCCC
RGKRSLGLDMSKPEGKAVLEELIRRADVFLTSFLPRSRRSLGIDVDDVRAINPKIIYARG
CCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHEECCCEEEEEEC
SALGPRGVESEKGGFDMTAFWARASCAASITPRSRDGMTPPPGPAYGDTISGTNLAGGIA
CCCCCCCCCCCCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
AALFSRERTGEPSVVDVSLLGSGLWAMGQSIALSLMLDEPLVAPEPGSLASPNPLSALYR
HHHHHHCCCCCCCEEEHHHHHCCHHHHHHHHEEEEEECCCCCCCCCCCCCCCCHHHHHEE
TSDGRFLSLVMLQAGRYWPDVCRHIDRPELADDPRFATAELIAANAEEAVKLLREAFAAR
CCCCCEEEHHHHHCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHH
TLAEWTERLATLSGPWAPVQDSLQVGGDAQIRANEYLLPAGEIELVSSPVQFDVSAPELG
HHHHHHHHHHHCCCCCCCCCHHHHCCCCCEEECCCEECCCCCEEEECCCCEEECCCCCCC
PAPEFAAQTEEILMELGLDWDRIIELKGAGAVT
CCCHHHHHHHHHHHHHCCCHHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9150242; 2361939 [H]