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The map label for this gene is nagA [H]

Identifier: 158315980

GI number: 158315980

Start: 4998404

End: 4999621

Strand: Reverse

Name: nagA [H]

Synonym: Franean1_4198

Alternate gene names: 158315980

Gene position: 4999621-4998404 (Counterclockwise)

Preceding gene: 158315982

Following gene: 158315973

Centisome position: 55.66

GC content: 77.91

Gene sequence:

>1218_bases
ATGATCGTTCTGGCCGGCGCCCGGGTGGTGACGCCGCACGGTGTCCTCGACCCCGGCCGGGTGCGCGTCGAGAACGGCCT
GATCACCGAGGTCGGCACCGAGGCCGGCACCGAGGTCGGGCCCACGGCCGGGCCCGTCGGTGGGGAGGCGGGCGGCGAGG
GGACGGGCGGCGAGGACATCGTCGACCTGGGCGGGTCCTGGCTGGTGCCCGGGTTTGTCGACCTGCACGTCCACGGCGGG
GGCGGGCACGACGTCACGGCGTCACCGGCCGATCTGGCCGCGGCGGTGGCCTTCCACCGGGCGCACGGCACGACCCGCAC
GCTGGTCTCGCTGGTGGCGGCGCCGGTGGAGCGCCTGGCCGAGCAGTTGTCCTGGGTGGCGGCGCTCACCGCGACCGGGC
CGGGGCCGGACGGCCATGTGGTCGGCGCGCATCTGGAGGGGCCGTTCCTCGCGCCCGCGCGCCGTGGCGCCCAGCCGGGT
GAGCATCTGCGCGGGCCTGACCGCGGTGTGTTCGCCGAGCTCGTCGCGGCGGGCGCGGGCACGCTGCGGGTGATCACCCT
CGCCCCGGAGCTGCCCGGGGCCGGCGCGGTGACCGAGGCCGCGCTCGCGGCGGGGGTGATCGCCGCCGCCGGCCACACGG
ACGCCACCTACGACGAGGCCGCCTCCGGTTTCGCGGCTGGCATGACGCTCGCCACCCACCTGTTCAACGGCATGCGCCCG
CTGCATCACCGCGAGCCCGGCCCGGCCGGGGCGGCGCTCGACGCCGGTGTGGCCTGCGAACTGATCAACGACGGTGTGCA
CGTGCACCCGGCGCTGCTGCGCCTGGTCGCCGCCGAGCCGGCGCGCCTGGTGCTGGTCACCGACGCGGTCGACGCGGCGG
GTGTCGGCGACGGCGACTACCTGCTGGGCGGCCACCCGGTCCGGGTCCGGGACGGGCAGGCCCGCCTGGCCGCCACCGGC
GCGCTCGCCGGCAGCACCCTGACGATGGACCTGGCGGTGCGCCGCGCCGTCGCGGCCGGGCTTGCGCTCGAGGTGGCGGT
CGCCGCCGCGGCGACGAACCCCGCCCGGGTGCTGGGCCTCGCCCACCGCTGCGGGTCGATCGCCCCCGGGCTGGACGCCG
ACCTCGTCGTGCTCGACGCCGATCTACGGGTCACGAGGGTCATGGCGGCCGGCAGGTGGGTCCCCGGTCCGGCTACCCGG
CCGATCGCGGCCGGGTAG

Upstream 100 bases:

>100_bases
GCCCGCAGCGTGGTGCCGCTACGGTGAGCGTGCCGCCACACCCGCGCACCGCCACGGGGCACGCCGGACCCGCGGGGGGA
GGCTCGAGGGGGAGGTTGGG

Downstream 100 bases:

>100_bases
CCGGCGCACCGGTCAGCGCACCGGTGCGTCAGGACGCCGCGTTCGACGTCCCGGGGTCGTTCGCGCTCGCGTTCTCGCGG
TCGCGAGGCGGACGGCTCAG

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MIVLAGARVVTPHGVLDPGRVRVENGLITEVGTEAGTEVGPTAGPVGGEAGGEGTGGEDIVDLGGSWLVPGFVDLHVHGG
GGHDVTASPADLAAAVAFHRAHGTTRTLVSLVAAPVERLAEQLSWVAALTATGPGPDGHVVGAHLEGPFLAPARRGAQPG
EHLRGPDRGVFAELVAAGAGTLRVITLAPELPGAGAVTEAALAAGVIAAAGHTDATYDEAASGFAAGMTLATHLFNGMRP
LHHREPGPAGAALDAGVACELINDGVHVHPALLRLVAAEPARLVLVTDAVDAAGVGDGDYLLGGHPVRVRDGQARLAATG
ALAGSTLTMDLAVRRAVAAGLALEVAVAAAATNPARVLGLAHRCGSIAPGLDADLVVLDADLRVTRVMAAGRWVPGPATR
PIAAG

Sequences:

>Translated_405_residues
MIVLAGARVVTPHGVLDPGRVRVENGLITEVGTEAGTEVGPTAGPVGGEAGGEGTGGEDIVDLGGSWLVPGFVDLHVHGG
GGHDVTASPADLAAAVAFHRAHGTTRTLVSLVAAPVERLAEQLSWVAALTATGPGPDGHVVGAHLEGPFLAPARRGAQPG
EHLRGPDRGVFAELVAAGAGTLRVITLAPELPGAGAVTEAALAAGVIAAAGHTDATYDEAASGFAAGMTLATHLFNGMRP
LHHREPGPAGAALDAGVACELINDGVHVHPALLRLVAAEPARLVLVTDAVDAAGVGDGDYLLGGHPVRVRDGQARLAATG
ALAGSTLTMDLAVRRAVAAGLALEVAVAAAATNPARVLGLAHRCGSIAPGLDADLVVLDADLRVTRVMAAGRWVPGPATR
PIAAG
>Mature_405_residues
MIVLAGARVVTPHGVLDPGRVRVENGLITEVGTEAGTEVGPTAGPVGGEAGGEGTGGEDIVDLGGSWLVPGFVDLHVHGG
GGHDVTASPADLAAAVAFHRAHGTTRTLVSLVAAPVERLAEQLSWVAALTATGPGPDGHVVGAHLEGPFLAPARRGAQPG
EHLRGPDRGVFAELVAAGAGTLRVITLAPELPGAGAVTEAALAAGVIAAAGHTDATYDEAASGFAAGMTLATHLFNGMRP
LHHREPGPAGAALDAGVACELINDGVHVHPALLRLVAAEPARLVLVTDAVDAAGVGDGDYLLGGHPVRVRDGQARLAATG
ALAGSTLTMDLAVRRAVAAGLALEVAVAAAATNPARVLGLAHRCGSIAPGLDADLVVLDADLRVTRVMAAGRWVPGPATR
PIAAG

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=382, Percent_Identity=35.8638743455497, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI224922791, Length=379, Percent_Identity=35.8839050131926, Blast_Score=176, Evalue=3e-44,
Organism=Escherichia coli, GI1786892, Length=402, Percent_Identity=32.5870646766169, Blast_Score=176, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17553768, Length=360, Percent_Identity=31.1111111111111, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI19920392, Length=355, Percent_Identity=34.9295774647887, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI281361140, Length=369, Percent_Identity=33.8753387533875, Blast_Score=169, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 40113; Mature: 40113

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLAGARVVTPHGVLDPGRVRVENGLITEVGTEAGTEVGPTAGPVGGEAGGEGTGGEDI
CEEEECCEEECCCCCCCCCCEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
VDLGGSWLVPGFVDLHVHGGGGHDVTASPADLAAAVAFHRAHGTTRTLVSLVAAPVERLA
HHCCCCEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EQLSWVAALTATGPGPDGHVVGAHLEGPFLAPARRGAQPGEHLRGPDRGVFAELVAAGAG
HHHHHHHEEEECCCCCCCCEEEEECCCCCCCHHHCCCCCCHHCCCCCCHHHHHHHHCCCC
TLRVITLAPELPGAGAVTEAALAAGVIAAAGHTDATYDEAASGFAAGMTLATHLFNGMRP
EEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
LHHREPGPAGAALDAGVACELINDGVHVHPALLRLVAAEPARLVLVTDAVDAAGVGDGDY
HHCCCCCCCCCHHCCCEEEEECCCCCEECHHHHHHHHCCCCEEEEEEECCCCCCCCCCCE
LLGGHPVRVRDGQARLAATGALAGSTLTMDLAVRRAVAAGLALEVAVAAAATNPARVLGL
EECCEEEEEECCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AHRCGSIAPGLDADLVVLDADLRVTRVMAAGRWVPGPATRPIAAG
HHHHCCCCCCCCCCEEEEECCCCEEHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIVLAGARVVTPHGVLDPGRVRVENGLITEVGTEAGTEVGPTAGPVGGEAGGEGTGGEDI
CEEEECCEEECCCCCCCCCCEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
VDLGGSWLVPGFVDLHVHGGGGHDVTASPADLAAAVAFHRAHGTTRTLVSLVAAPVERLA
HHCCCCEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EQLSWVAALTATGPGPDGHVVGAHLEGPFLAPARRGAQPGEHLRGPDRGVFAELVAAGAG
HHHHHHHEEEECCCCCCCCEEEEECCCCCCCHHHCCCCCCHHCCCCCCHHHHHHHHCCCC
TLRVITLAPELPGAGAVTEAALAAGVIAAAGHTDATYDEAASGFAAGMTLATHLFNGMRP
EEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
LHHREPGPAGAALDAGVACELINDGVHVHPALLRLVAAEPARLVLVTDAVDAAGVGDGDY
HHCCCCCCCCCHHCCCEEEEECCCCCEECHHHHHHHHCCCCEEEEEEECCCCCCCCCCCE
LLGGHPVRVRDGQARLAATGALAGSTLTMDLAVRRAVAAGLALEVAVAAAATNPARVLGL
EECCEEEEEECCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AHRCGSIAPGLDADLVVLDADLRVTRVMAAGRWVPGPATRPIAAG
HHHHCCCCCCCCCCEEEEECCCCEEHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]