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The map label for this gene is bioA [H]

Identifier: 158315967

GI number: 158315967

Start: 4977302

End: 4978588

Strand: Reverse

Name: bioA [H]

Synonym: Franean1_4185

Alternate gene names: 158315967

Gene position: 4978588-4977302 (Counterclockwise)

Preceding gene: 158315972

Following gene: 158315966

Centisome position: 55.43

GC content: 73.43

Gene sequence:

>1287_bases
ATGGACGCCTCCGACCTGGTCACCCGGGACCGCGCGGTCGTCTGGCATCCGTACGCCTCCGTGCGCGACCAGGCGCCGCT
GTTCGCCGTCGCCTCCGCCGCCGGGGTGCGCCTGACCCTCACCGACGGCCGCGAGCTGCTCGACGGGATGTCGTCGTGGT
GGGCGGCGATCCACGGATACCGCCATCCCGTCCTGGACCAGGCCGCCCGCGACCAGCTGGACCGGATGTCGCACGTCATG
TTCGGCGGGCTCACCCACGAGCCCGCCGTCGCGCTGGCCGAGCTGCTTGTACGGGTCACCCCACCCGGCCTGGAGCGGGT
GTTCTTCTGCGACTCCGGCTCCGTCGCCGTCGAGGTCGCGATCAAGATGGCGCTGCAGTACCAGGCCGGACGCGGCCGGC
CCGGGCGGACGAGGCTGCTCACGATCCGCCGCGGCTACCACGGTGACACCTCCGGCGCGATGTCGGTCTGCGATCCCGAC
ACCGGCATGCACCACCTGTTCACCGGCCTGCTGGCCCGGCATCTGTTCGCCCCCGCCCCGGCTCCCGGCTTCGACGAGCC
GGTCACCGATGACGACCTCGCCGACGTCGAACGCCTGCTCGCCGCCCACGAGGGGGAGATCGCCGCGGTCGTTCTCGAAC
CGGTCGTGCAGGGCGCCGGCGCGATGCGCTTCTACGCCCCCGGCTGGCTGGCCCGGGTCCGCGAGCTGTGCGACCGGCAC
CGGGTGCTGCTCGTTGCCGACGAGATCGCGACCGGCTTCGGGCGCACCGGGGAGCTGTTCGGCTGCGATCACGCCGGGAT
CACCCCGGACATCATGTGTGTCGGCAAGGCGATGACCGGCGGTTACCTGACGATGGGCGCCACCCTGTGCACCACCGAGG
TGGCCGACGGCGTCTGCGCGTCGGAGGCGGGCGCGTTCATGCACGGCCCCACGTTCATGGCCAACCCGCTGGCCGCGGCG
GTCTCGCGGGCGAGTGTCGAGCTGCTGCTCGCCTCCCCGTGGAGGGAGCGGGTCCGCGTCGTGCACGACGCGCTGGCGGC
CGGGCTCGCGCCCGCCGCCGACCTGCCGGGCGTCGCGGACGTCCGCACTCTCGGCGCCATCGGCGTGATCGAGACCCACC
GTCCGGTCGACATGGCCGTCATCCAGCCGCTGCTCGTCGAGCTGGGGGTGTGGGTGCGCCCGTTCGGACGGCTCGTCTAC
GCGATGCCGCCGTTCGTGATGGAGCCGGCGGACGTCGCCACCCTGACCGCCGCCATGGTCGCCGCCGTCGCCGCCACCAC
CGGCTGA

Upstream 100 bases:

>100_bases
CTGTGGCACGCCCCACCGGCCGAAGCCGGGTGAGCAGCGGCACAGCCCCGCGCCCGCGGCCACCGGCCCGCTCCGGCGGC
CGGTGGGAGAAGCTGGGGCC

Downstream 100 bases:

>100_bases
CCGCTCACCGGCCGGCGGTGGCCGGCCGGCGGTGGCCGGCCGCGGGGCCGTCGGGCCGGCGCGACGGCCGTCCGGCGGCC
TGGCGACCCACCCCATCAGG

Product: adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Products: NA

Alternate protein names: 7,8-diamino-pelargonic acid aminotransferase; DAPA AT; DAPA aminotransferase; Diaminopelargonic acid synthase [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MDASDLVTRDRAVVWHPYASVRDQAPLFAVASAAGVRLTLTDGRELLDGMSSWWAAIHGYRHPVLDQAARDQLDRMSHVM
FGGLTHEPAVALAELLVRVTPPGLERVFFCDSGSVAVEVAIKMALQYQAGRGRPGRTRLLTIRRGYHGDTSGAMSVCDPD
TGMHHLFTGLLARHLFAPAPAPGFDEPVTDDDLADVERLLAAHEGEIAAVVLEPVVQGAGAMRFYAPGWLARVRELCDRH
RVLLVADEIATGFGRTGELFGCDHAGITPDIMCVGKAMTGGYLTMGATLCTTEVADGVCASEAGAFMHGPTFMANPLAAA
VSRASVELLLASPWRERVRVVHDALAAGLAPAADLPGVADVRTLGAIGVIETHRPVDMAVIQPLLVELGVWVRPFGRLVY
AMPPFVMEPADVATLTAAMVAAVAATTG

Sequences:

>Translated_428_residues
MDASDLVTRDRAVVWHPYASVRDQAPLFAVASAAGVRLTLTDGRELLDGMSSWWAAIHGYRHPVLDQAARDQLDRMSHVM
FGGLTHEPAVALAELLVRVTPPGLERVFFCDSGSVAVEVAIKMALQYQAGRGRPGRTRLLTIRRGYHGDTSGAMSVCDPD
TGMHHLFTGLLARHLFAPAPAPGFDEPVTDDDLADVERLLAAHEGEIAAVVLEPVVQGAGAMRFYAPGWLARVRELCDRH
RVLLVADEIATGFGRTGELFGCDHAGITPDIMCVGKAMTGGYLTMGATLCTTEVADGVCASEAGAFMHGPTFMANPLAAA
VSRASVELLLASPWRERVRVVHDALAAGLAPAADLPGVADVRTLGAIGVIETHRPVDMAVIQPLLVELGVWVRPFGRLVY
AMPPFVMEPADVATLTAAMVAAVAATTG
>Mature_428_residues
MDASDLVTRDRAVVWHPYASVRDQAPLFAVASAAGVRLTLTDGRELLDGMSSWWAAIHGYRHPVLDQAARDQLDRMSHVM
FGGLTHEPAVALAELLVRVTPPGLERVFFCDSGSVAVEVAIKMALQYQAGRGRPGRTRLLTIRRGYHGDTSGAMSVCDPD
TGMHHLFTGLLARHLFAPAPAPGFDEPVTDDDLADVERLLAAHEGEIAAVVLEPVVQGAGAMRFYAPGWLARVRELCDRH
RVLLVADEIATGFGRTGELFGCDHAGITPDIMCVGKAMTGGYLTMGATLCTTEVADGVCASEAGAFMHGPTFMANPLAAA
VSRASVELLLASPWRERVRVVHDALAAGLAPAADLPGVADVRTLGAIGVIETHRPVDMAVIQPLLVELGVWVRPFGRLVY
AMPPFVMEPADVATLTAAMVAAVAATTG

Specific function: Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=395, Percent_Identity=28.8607594936709, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI284507298, Length=236, Percent_Identity=33.4745762711864, Blast_Score=102, Evalue=9e-22,
Organism=Escherichia coli, GI1786991, Length=424, Percent_Identity=56.8396226415094, Blast_Score=487, Evalue=1e-139,
Organism=Escherichia coli, GI145693181, Length=352, Percent_Identity=33.5227272727273, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI1789016, Length=353, Percent_Identity=31.728045325779, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788044, Length=363, Percent_Identity=31.9559228650138, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI1789759, Length=302, Percent_Identity=34.7682119205298, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1787560, Length=362, Percent_Identity=30.3867403314917, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1786349, Length=343, Percent_Identity=29.4460641399417, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI25144271, Length=433, Percent_Identity=25.8660508083141, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI32564660, Length=360, Percent_Identity=28.6111111111111, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI25144274, Length=245, Percent_Identity=30.6122448979592, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17541228, Length=336, Percent_Identity=24.702380952381, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324386, Length=462, Percent_Identity=39.1774891774892, Blast_Score=365, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6323470, Length=436, Percent_Identity=27.5229357798165, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6321456, Length=334, Percent_Identity=25.748502994012, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357415, Length=389, Percent_Identity=27.5064267352185, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28574759, Length=367, Percent_Identity=27.7929155313352, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI161085790, Length=367, Percent_Identity=27.7929155313352, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356575, Length=363, Percent_Identity=23.6914600550964, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR005815
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.62 [H]

Molecular weight: Translated: 45435; Mature: 45435

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDASDLVTRDRAVVWHPYASVRDQAPLFAVASAAGVRLTLTDGRELLDGMSSWWAAIHGY
CCCHHHHHCCCEEEECCCHHHCCCCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHHCC
RHPVLDQAARDQLDRMSHVMFGGLTHEPAVALAELLVRVTPPGLERVFFCDSGSVAVEVA
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCEEHHHH
IKMALQYQAGRGRPGRTRLLTIRRGYHGDTSGAMSVCDPDTGMHHLFTGLLARHLFAPAP
HHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCC
APGFDEPVTDDDLADVERLLAAHEGEIAAVVLEPVVQGAGAMRFYAPGWLARVRELCDRH
CCCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHCCCCCEEEECCHHHHHHHHHHHCC
RVLLVADEIATGFGRTGELFGCDHAGITPDIMCVGKAMTGGYLTMGATLCTTEVADGVCA
CEEEEEHHHHHCCCCCCCEECCCCCCCCCCCEEECCCCCCCCHHHCHHHHHHHHHCCHHH
SEAGAFMHGPTFMANPLAAAVSRASVELLLASPWRERVRVVHDALAAGLAPAADLPGVAD
HHCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHH
VRTLGAIGVIETHRPVDMAVIQPLLVELGVWVRPFGRLVYAMPPFVMEPADVATLTAAMV
HHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
AAVAATTG
HHHHHCCC
>Mature Secondary Structure
MDASDLVTRDRAVVWHPYASVRDQAPLFAVASAAGVRLTLTDGRELLDGMSSWWAAIHGY
CCCHHHHHCCCEEEECCCHHHCCCCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHHCC
RHPVLDQAARDQLDRMSHVMFGGLTHEPAVALAELLVRVTPPGLERVFFCDSGSVAVEVA
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCEEHHHH
IKMALQYQAGRGRPGRTRLLTIRRGYHGDTSGAMSVCDPDTGMHHLFTGLLARHLFAPAP
HHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCC
APGFDEPVTDDDLADVERLLAAHEGEIAAVVLEPVVQGAGAMRFYAPGWLARVRELCDRH
CCCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHCCCCCEEEECCHHHHHHHHHHHCC
RVLLVADEIATGFGRTGELFGCDHAGITPDIMCVGKAMTGGYLTMGATLCTTEVADGVCA
CEEEEEHHHHHCCCCCCCEECCCCCCCCCCCEEECCCCCCCCHHHCHHHHHHHHHCCHHH
SEAGAFMHGPTFMANPLAAAVSRASVELLLASPWRERVRVVHDALAAGLAPAADLPGVAD
HHCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHH
VRTLGAIGVIETHRPVDMAVIQPLLVELGVWVRPFGRLVYAMPPFVMEPADVATLTAAMV
HHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
AAVAATTG
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]