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The map label for this gene is yajO [H]

Identifier: 158315477

GI number: 158315477

Start: 4359147

End: 4360769

Strand: Reverse

Name: yajO [H]

Synonym: Franean1_3682

Alternate gene names: 158315477

Gene position: 4360769-4359147 (Counterclockwise)

Preceding gene: 158315480

Following gene: 158315476

Centisome position: 48.55

GC content: 73.14

Gene sequence:

>1623_bases
ATGGAGTCCAGGGCGGGTGGCGAGCGTTCGCGGGCCGGGCGCCCGACGGCGACGGAGGCAGCCAGGCTGACCGAGCGGCT
CCGGCGGGCCGCCGTCGACACGTTCCTGGAGTCGGGTTACGACGGCACCACGATGGAGGCCGTCGCGCAGGCCGCGGGGA
TCACCAAGAGCACCTTGTATGCCCGCTATCCCGACAAGCGAACTCTGTTCATCGCGGTGAGCTCGTGGGCGCTCACCCGC
CAGGAGCGCGACGAGCGCGTCCTCGAACCGCTGCCCGACGACCTCGCCGAGAGCCTGACCGTGATCGCGCGGGCGATCCT
GGCCCGCTCGGTCGACCCCGACATCGTCCGCCTGAGCCGGATGGCGATCGCCGAGTCGGCGCGCTTCCCCGAGTTCGCGG
CGAGCTCGCAGGCCGTCACCTGGTCACCGCGGGTGCAACTGATCATTGATCTGCTACGCAGGCACGAGAGCGCGGGCACC
GTGGTCGTCGGGGACGTCGACCTCGCCGCCGAGCAGTTCTTCGCCATGGTCGGCGCGATGCCGGCGTGGCTGGCCGCCTA
CGGCATCTACCGGACCCCCGAGGTCGAGGAGGAGCACCTCCACCACGCGGTGAGCCTCTTCCTCAACGGCGTCCTGGCCA
GGCCGGAGACCATGCCGGCCCCGCACCCGACCGAGGCCGCCAGGCCCGCCGGGGAGGGACCGGCCGTCCCTCGTGCGAGC
TGGCCGATGGAGTACCGGCGGCTCGGCCGCAGCGGGCTGAACGTCTCGCGGCTCGCGCTGGGAGTCGCGGCTCTCGGCGC
CGGGCCCGCGGACCATGACGAGCGGGCCGCGATCGGCGTCATCCACCGCTTCCTCGACGCCGGCGGCAACCTCCTCGACA
CCACCGCCGCGGGCGACATCGGCCGGGGTGGCACGGACCCGGACGGCGCCGCGGCGGAGCTCTGCGGCCGTGCCGTTCGG
GACAGGCGCTCGAGCGTCGTCCTGGCCTCGAGCGTCGGGCGGCCGAGCGGGCAGGGCCCCCACGACGGCGGGAACAGCCG
CCGTCACATCCGGGCCGCCTGCGAGGCGACCCTCCGCCGGCTCCGGACGGACTATCTCGACCTCCTCCAACTCGACGCCG
ACGACCCGACGACCCCGCTGGAGGAGACGATCGACGCGCTGGACGACCTGGTGCGCGCCGGGAAGGTCCTCTACGTCGGC
GTCGCCAACCTGCACGTCTACCGGGTGACGAAGGCGCTGTCGGTCAGCGACCGGCTCGGCCGGGCCCGTTTCATCTCGTT
CCGCGGCCCGTACGGCCTGCTCTCGCGGGAGCTCGAACACGAGCACCTCCCGCTGCTGGCGGAGGAAGGCCTCGGCCTGA
TCAGCACGAGCTCACTCCGCTCCCCCGGGCACGGGCACGGGCACGGGCACGCCACTGTCGCCGCCACGGAGGCCGCGGCG
GCGGAGCTCGGGTGCACGACCACGCAGCTGTCGCTGGCCTGGCAACTGACGAGATCCGTCACCTCGATCACGCTCGACGT
CGCCTCCGCGGCCCAGCTGGACGAGCACCTCGCGGCCCTGGGCATCGAGATCCCCACCGAGATCGCGGCAGCACTGGAAC
AGGTCTCCCGTCCCCAGGGGTAA

Upstream 100 bases:

>100_bases
GCAACAGGCGGACCAGGACCGCGCCCGCCTCCCGTGAGGGCGCCCGGACGGCGCCGCCGTCGACCTTGACCAGAATCCGA
CGCACTCGTAGCTTTAGCGG

Downstream 100 bases:

>100_bases
CGGTCCGCGGCCGCGCCGGCCGGCCGGTACGGCCGCGGACGGCGCGCCGCCCAGCTGACAGCGGCGCGGCGGCTTCGCCT
GCTGATACGCGTGGCCGTGA

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MESRAGGERSRAGRPTATEAARLTERLRRAAVDTFLESGYDGTTMEAVAQAAGITKSTLYARYPDKRTLFIAVSSWALTR
QERDERVLEPLPDDLAESLTVIARAILARSVDPDIVRLSRMAIAESARFPEFAASSQAVTWSPRVQLIIDLLRRHESAGT
VVVGDVDLAAEQFFAMVGAMPAWLAAYGIYRTPEVEEEHLHHAVSLFLNGVLARPETMPAPHPTEAARPAGEGPAVPRAS
WPMEYRRLGRSGLNVSRLALGVAALGAGPADHDERAAIGVIHRFLDAGGNLLDTTAAGDIGRGGTDPDGAAAELCGRAVR
DRRSSVVLASSVGRPSGQGPHDGGNSRRHIRAACEATLRRLRTDYLDLLQLDADDPTTPLEETIDALDDLVRAGKVLYVG
VANLHVYRVTKALSVSDRLGRARFISFRGPYGLLSRELEHEHLPLLAEEGLGLISTSSLRSPGHGHGHGHATVAATEAAA
AELGCTTTQLSLAWQLTRSVTSITLDVASAAQLDEHLAALGIEIPTEIAAALEQVSRPQG

Sequences:

>Translated_540_residues
MESRAGGERSRAGRPTATEAARLTERLRRAAVDTFLESGYDGTTMEAVAQAAGITKSTLYARYPDKRTLFIAVSSWALTR
QERDERVLEPLPDDLAESLTVIARAILARSVDPDIVRLSRMAIAESARFPEFAASSQAVTWSPRVQLIIDLLRRHESAGT
VVVGDVDLAAEQFFAMVGAMPAWLAAYGIYRTPEVEEEHLHHAVSLFLNGVLARPETMPAPHPTEAARPAGEGPAVPRAS
WPMEYRRLGRSGLNVSRLALGVAALGAGPADHDERAAIGVIHRFLDAGGNLLDTTAAGDIGRGGTDPDGAAAELCGRAVR
DRRSSVVLASSVGRPSGQGPHDGGNSRRHIRAACEATLRRLRTDYLDLLQLDADDPTTPLEETIDALDDLVRAGKVLYVG
VANLHVYRVTKALSVSDRLGRARFISFRGPYGLLSRELEHEHLPLLAEEGLGLISTSSLRSPGHGHGHGHATVAATEAAA
AELGCTTTQLSLAWQLTRSVTSITLDVASAAQLDEHLAALGIEIPTEIAAALEQVSRPQG
>Mature_540_residues
MESRAGGERSRAGRPTATEAARLTERLRRAAVDTFLESGYDGTTMEAVAQAAGITKSTLYARYPDKRTLFIAVSSWALTR
QERDERVLEPLPDDLAESLTVIARAILARSVDPDIVRLSRMAIAESARFPEFAASSQAVTWSPRVQLIIDLLRRHESAGT
VVVGDVDLAAEQFFAMVGAMPAWLAAYGIYRTPEVEEEHLHHAVSLFLNGVLARPETMPAPHPTEAARPAGEGPAVPRAS
WPMEYRRLGRSGLNVSRLALGVAALGAGPADHDERAAIGVIHRFLDAGGNLLDTTAAGDIGRGGTDPDGAAAELCGRAVR
DRRSSVVLASSVGRPSGQGPHDGGNSRRHIRAACEATLRRLRTDYLDLLQLDADDPTTPLEETIDALDDLVRAGKVLYVG
VANLHVYRVTKALSVSDRLGRARFISFRGPYGLLSRELEHEHLPLLAEEGLGLISTSSLRSPGHGHGHGHATVAATEAAA
AELGCTTTQLSLAWQLTRSVTSITLDVASAAQLDEHLAALGIEIPTEIAAALEQVSRPQG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=314, Percent_Identity=28.6624203821656, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI4504825, Length=312, Percent_Identity=28.525641025641, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI27436971, Length=315, Percent_Identity=28.2539682539683, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI27436962, Length=320, Percent_Identity=26.875, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI27436964, Length=315, Percent_Identity=26.6666666666667, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI27436966, Length=315, Percent_Identity=26.3492063492064, Blast_Score=93, Evalue=7e-19,
Organism=Escherichia coli, GI87081735, Length=328, Percent_Identity=33.8414634146341, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1789375, Length=336, Percent_Identity=27.0833333333333, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1789199, Length=343, Percent_Identity=26.530612244898, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1788070, Length=335, Percent_Identity=25.9701492537313, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788081, Length=292, Percent_Identity=26.027397260274, Blast_Score=73, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=338, Percent_Identity=26.3313609467456, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323998, Length=216, Percent_Identity=27.7777777777778, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319951, Length=335, Percent_Identity=24.4776119402985, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6319958, Length=192, Percent_Identity=26.0416666666667, Blast_Score=81, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6322615, Length=143, Percent_Identity=30.0699300699301, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24646155, Length=221, Percent_Identity=28.5067873303167, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24646159, Length=227, Percent_Identity=29.5154185022026, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 57695; Mature: 57695

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESRAGGERSRAGRPTATEAARLTERLRRAAVDTFLESGYDGTTMEAVAQAAGITKSTLY
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHE
ARYPDKRTLFIAVSSWALTRQERDERVLEPLPDDLAESLTVIARAILARSVDPDIVRLSR
EECCCCEEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
MAIAESARFPEFAASSQAVTWSPRVQLIIDLLRRHESAGTVVVGDVDLAAEQFFAMVGAM
HHHHHHCCCCCHHCCCCCEEECCHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHH
PAWLAAYGIYRTPEVEEEHLHHAVSLFLNGVLARPETMPAPHPTEAARPAGEGPAVPRAS
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCC
WPMEYRRLGRSGLNVSRLALGVAALGAGPADHDERAAIGVIHRFLDAGGNLLDTTAAGDI
CCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCC
GRGGTDPDGAAAELCGRAVRDRRSSVVLASSVGRPSGQGPHDGGNSRRHIRAACEATLRR
CCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LRTDYLDLLQLDADDPTTPLEETIDALDDLVRAGKVLYVGVANLHVYRVTKALSVSDRLG
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCEEEEHHHHHHHHHHHHC
RARFISFRGPYGLLSRELEHEHLPLLAEEGLGLISTSSLRSPGHGHGHGHATVAATEAAA
CEEEEEECCCHHHHHHHHHHHCCCCHHHCCCCEEECCCCCCCCCCCCCCCEEEEEHHHHH
AELGCTTTQLSLAWQLTRSVTSITLDVASAAQLDEHLAALGIEIPTEIAAALEQVSRPQG
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MESRAGGERSRAGRPTATEAARLTERLRRAAVDTFLESGYDGTTMEAVAQAAGITKSTLY
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHE
ARYPDKRTLFIAVSSWALTRQERDERVLEPLPDDLAESLTVIARAILARSVDPDIVRLSR
EECCCCEEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
MAIAESARFPEFAASSQAVTWSPRVQLIIDLLRRHESAGTVVVGDVDLAAEQFFAMVGAM
HHHHHHCCCCCHHCCCCCEEECCHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHH
PAWLAAYGIYRTPEVEEEHLHHAVSLFLNGVLARPETMPAPHPTEAARPAGEGPAVPRAS
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCC
WPMEYRRLGRSGLNVSRLALGVAALGAGPADHDERAAIGVIHRFLDAGGNLLDTTAAGDI
CCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCC
GRGGTDPDGAAAELCGRAVRDRRSSVVLASSVGRPSGQGPHDGGNSRRHIRAACEATLRR
CCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LRTDYLDLLQLDADDPTTPLEETIDALDDLVRAGKVLYVGVANLHVYRVTKALSVSDRLG
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCEEEEHHHHHHHHHHHHC
RARFISFRGPYGLLSRELEHEHLPLLAEEGLGLISTSSLRSPGHGHGHGHATVAATEAAA
CEEEEEECCCHHHHHHHHHHHCCCCHHHCCCCEEECCCCCCCCCCCCCCCEEEEEHHHHH
AELGCTTTQLSLAWQLTRSVTSITLDVASAAQLDEHLAALGIEIPTEIAAALEQVSRPQG
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]