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The map label for this gene is pcm [H]

Identifier: 158315317

GI number: 158315317

Start: 4179077

End: 4180324

Strand: Reverse

Name: pcm [H]

Synonym: Franean1_3518

Alternate gene names: 158315317

Gene position: 4180324-4179077 (Counterclockwise)

Preceding gene: 158315318

Following gene: 158315316

Centisome position: 46.54

GC content: 71.39

Gene sequence:

>1248_bases
ATGAGCGTCGGCACCACGAGCAGCGAGAGCGAGAGTCTCCGGCACGCGATGGTCGACCGGCTGGCCGCCGATCATGCGGC
GAAAGGCCTTGCGCTGCGGCCCGAGGTGGAGGCGGCGATGCGGACCGTCCCCCGCGAGCTGTACACGCCGGGCCTTCCAC
CGGAGCAGGCGTACGAGAACGAAGCGGTTCTCAAGAAGCGGCGCGGTACGGAAGTGATCAGTTCGGTGTCGGCGCCGTTC
CTGATCGCGGAGATGCTCGGTCAGGCCGCGGACGCGCTCGGTGGGCTGGCGGGCTGTCACGCGCTGGAGATCGGTAGCGG
TGGCTACAACGCGTCGCTGTTGCGGGAGCTCGTCGGCCCGTCAGGGTCGGTCACAACCGTCGATATCGACCCCGAGGTGA
CCGGCCGGGCGGTCGCCTGCCTGGCGGCGGCGGGCTACACCGACCTCACCGTGGTGTGCGCGGACGCCGAGCATCCGATC
ACCTCGGGCCACCGCTACGACCTGATCATTGTCACCGTCGGGGCGTGGGACATCCCGCCGGCGTGGTGTGAGCAGCTCCG
TGACGGCGGTGTGCTGGTGGTGCCGCTGCGCACGTTCGGGATCACCAAGTCGTGGGCACTGCGCCGCCGCGGGGACCGCC
TGGTCAGTGAGAGCGACCGCCAGTGCGGGTTCGTCTTCATGCAGGGCGACGGGGCCCACAAGGTGCGGTACGTCGACATC
GCTGATGGTGTCCGCCTGCGGATGGACGAGGGCCAGCAGGTCGATCCCGCCGTTCTCGAGGGACTTCTGGCGCAGCCTCG
GGAGGAGGCCTGGGCCGGGGTGAGCCTGCCGCCCCGTACCGACCTGATCGACCTGAACCTGTGGCTGGCGACCCGCCTCA
CCCACGAGGCGGGCCAGTTCGTGGTGCTGCTGGCGGAGGAGACGGCGATCGAGGCCGGCACGGTCGCGCCCTCCTGGCAG
CACGGCACCCCGGCGACCCTGCGCGACGGCACGCTCGCCTACCGGTCGGCTCTGCGCTGGACCGGCCGGCGGTTCGATCT
CGGTGCCTACGCCCACGGGTCCAAGGCCGCCGCGGCGGCCGGGCGGATGGTCGAACACATGCGCGCGTGGGTGGACGCGG
GCAGCCCGGCTCCGGTGCTGCACGTCCTTCCCGCGCACACCCCCGACGGCGACCTGCCGGCCGGAGCGGTCCTGAACAAG
CGGCACAACCGCCTCGTCCTGACCTTCACCCCCACCGCGTCCGTATAG

Upstream 100 bases:

>100_bases
CGAGTACGAGGCAGAACCGGTAGCTGATTCCCGGCTTGCTGGAATTCACCGGGGCCACCCGAACCGCGGCGGCCCGCACG
CGTCGGGAGAGGACACCGCG

Downstream 100 bases:

>100_bases
CCGACCGTCCGGAAGGATCATCGTTGAACGCCGCGACCTCGACCCCCGACGCCACCCCCGACGAGCTGCGCGCGGCCATG
GTCGACCGCCTCGCCGCCTC

Product: protein-L-isoaspartate(D-aspartate) O-methyltransferase

Products: NA

Alternate protein names: L-isoaspartyl protein carboxyl methyltransferase; Protein L-isoaspartyl methyltransferase; Protein-beta-aspartate methyltransferase; PIMT [H]

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MSVGTTSSESESLRHAMVDRLAADHAAKGLALRPEVEAAMRTVPRELYTPGLPPEQAYENEAVLKKRRGTEVISSVSAPF
LIAEMLGQAADALGGLAGCHALEIGSGGYNASLLRELVGPSGSVTTVDIDPEVTGRAVACLAAAGYTDLTVVCADAEHPI
TSGHRYDLIIVTVGAWDIPPAWCEQLRDGGVLVVPLRTFGITKSWALRRRGDRLVSESDRQCGFVFMQGDGAHKVRYVDI
ADGVRLRMDEGQQVDPAVLEGLLAQPREEAWAGVSLPPRTDLIDLNLWLATRLTHEAGQFVVLLAEETAIEAGTVAPSWQ
HGTPATLRDGTLAYRSALRWTGRRFDLGAYAHGSKAAAAAGRMVEHMRAWVDAGSPAPVLHVLPAHTPDGDLPAGAVLNK
RHNRLVLTFTPTASV

Sequences:

>Translated_415_residues
MSVGTTSSESESLRHAMVDRLAADHAAKGLALRPEVEAAMRTVPRELYTPGLPPEQAYENEAVLKKRRGTEVISSVSAPF
LIAEMLGQAADALGGLAGCHALEIGSGGYNASLLRELVGPSGSVTTVDIDPEVTGRAVACLAAAGYTDLTVVCADAEHPI
TSGHRYDLIIVTVGAWDIPPAWCEQLRDGGVLVVPLRTFGITKSWALRRRGDRLVSESDRQCGFVFMQGDGAHKVRYVDI
ADGVRLRMDEGQQVDPAVLEGLLAQPREEAWAGVSLPPRTDLIDLNLWLATRLTHEAGQFVVLLAEETAIEAGTVAPSWQ
HGTPATLRDGTLAYRSALRWTGRRFDLGAYAHGSKAAAAAGRMVEHMRAWVDAGSPAPVLHVLPAHTPDGDLPAGAVLNK
RHNRLVLTFTPTASV
>Mature_414_residues
SVGTTSSESESLRHAMVDRLAADHAAKGLALRPEVEAAMRTVPRELYTPGLPPEQAYENEAVLKKRRGTEVISSVSAPFL
IAEMLGQAADALGGLAGCHALEIGSGGYNASLLRELVGPSGSVTTVDIDPEVTGRAVACLAAAGYTDLTVVCADAEHPIT
SGHRYDLIIVTVGAWDIPPAWCEQLRDGGVLVVPLRTFGITKSWALRRRGDRLVSESDRQCGFVFMQGDGAHKVRYVDIA
DGVRLRMDEGQQVDPAVLEGLLAQPREEAWAGVSLPPRTDLIDLNLWLATRLTHEAGQFVVLLAEETAIEAGTVAPSWQH
GTPATLRDGTLAYRSALRWTGRRFDLGAYAHGSKAAAAAGRMVEHMRAWVDAGSPAPVLHVLPAHTPDGDLPAGAVLNKR
HNRLVLTFTPTASV

Specific function: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins [H]

COG id: COG2518

COG function: function code O; Protein-L-isoaspartate carboxylmethyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000682 [H]

Pfam domain/function: PF01135 PCMT [H]

EC number: =2.1.1.77 [H]

Molecular weight: Translated: 44300; Mature: 44169

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVGTTSSESESLRHAMVDRLAADHAAKGLALRPEVEAAMRTVPRELYTPGLPPEQAYEN
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHCCHHHCCCCCCHHHHHCC
EAVLKKRRGTEVISSVSAPFLIAEMLGQAADALGGLAGCHALEIGSGGYNASLLRELVGP
HHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHCC
SGSVTTVDIDPEVTGRAVACLAAAGYTDLTVVCADAEHPITSGHRYDLIIVTVGAWDIPP
CCCEEEEECCCCCCCHHEEHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEEEECCCCCCH
AWCEQLRDGGVLVVPLRTFGITKSWALRRRGDRLVSESDRQCGFVFMQGDGAHKVRYVDI
HHHHHHCCCCEEEEEHHHHCCCHHHHHHHHCCHHHCCCCCCEEEEEEECCCCCEEEEEEE
ADGVRLRMDEGQQVDPAVLEGLLAQPREEAWAGVSLPPRTDLIDLNLWLATRLTHEAGQF
CCCEEEEECCCCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCEEEEEEHHHHHHHHCCCCE
VVLLAEETAIEAGTVAPSWQHGTPATLRDGTLAYRSALRWTGRRFDLGAYAHGSKAAAAA
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCHHHHHH
GRMVEHMRAWVDAGSPAPVLHVLPAHTPDGDLPAGAVLNKRHNRLVLTFTPTASV
HHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
SVGTTSSESESLRHAMVDRLAADHAAKGLALRPEVEAAMRTVPRELYTPGLPPEQAYEN
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHCCHHHCCCCCCHHHHHCC
EAVLKKRRGTEVISSVSAPFLIAEMLGQAADALGGLAGCHALEIGSGGYNASLLRELVGP
HHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHCC
SGSVTTVDIDPEVTGRAVACLAAAGYTDLTVVCADAEHPITSGHRYDLIIVTVGAWDIPP
CCCEEEEECCCCCCCHHEEHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEEEECCCCCCH
AWCEQLRDGGVLVVPLRTFGITKSWALRRRGDRLVSESDRQCGFVFMQGDGAHKVRYVDI
HHHHHHCCCCEEEEEHHHHCCCHHHHHHHHCCHHHCCCCCCEEEEEEECCCCCEEEEEEE
ADGVRLRMDEGQQVDPAVLEGLLAQPREEAWAGVSLPPRTDLIDLNLWLATRLTHEAGQF
CCCEEEEECCCCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCEEEEEEHHHHHHHHCCCCE
VVLLAEETAIEAGTVAPSWQHGTPATLRDGTLAYRSALRWTGRRFDLGAYAHGSKAAAAA
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCHHHHHH
GRMVEHMRAWVDAGSPAPVLHVLPAHTPDGDLPAGAVLNKRHNRLVLTFTPTASV
HHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA