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The map label for this gene is pcp [H]

Identifier: 158315240

GI number: 158315240

Start: 4070755

End: 4071195

Strand: Direct

Name: pcp [H]

Synonym: Franean1_3440

Alternate gene names: 158315240

Gene position: 4070755-4071195 (Clockwise)

Preceding gene: 158315236

Following gene: 158315242

Centisome position: 45.32

GC content: 66.89

Gene sequence:

>441_bases
ATGCAGGACGATCTACCGGATCAGACCCCACCACGAGGGCGAATCCCGCAGACAGATCACAACTCGACACGCGCCCTAGA
GGACGACCTCACTGATCCGAACGGTCCGGTGGCGTACTGGTCGACCCTTCCGCTGCGCGCGATGGTCCTGGCGATGCGCC
AGGCCGGCATCCCTGCCGACATCTCCGACACGCCCGGCACGTTGATGTGCAACCACCTCATGTACGGCGTGCTGCGATAC
GTCGCGACCCATGACCTCCCGCCCCGCGTCGGATGGATCCACATGCCCCACCTCCCGGAGGTGGCCGCACTGGATAGCAA
TCTCGGCGCACCGAGCATGTCGCTGGCGACGTCGGTCGCCGGAGTCCGGGTCGCCGTCTCGGCAACGCTGGAGCACGCGA
GCGACGTCCACGCCCACGTCCACTCCCGGCTGCAGATCTGA

Upstream 100 bases:

>100_bases
GAACTGCGCCCGCAGCCGCGCCGGGTACGGGCCGAACCCGCCGATCGGCAGGTAAGGCTCGATGAACGCCCACTCCTCGT
CCGTCAGTTGCATCCGTGTC

Downstream 100 bases:

>100_bases
GCGGGCACACTCGCATTGGCCGGACGCGCCGGCCCGCCTGGTCACCAGCCACACGGCGGTCATCCTCGATGGGGCGAACA
TCCGACCGCGTGGGAAGGCC

Product: pyroglutamyl-peptidase I

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase; Pyroglutamyl-peptidase I; PGP-I; Pyrase [H]

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MQDDLPDQTPPRGRIPQTDHNSTRALEDDLTDPNGPVAYWSTLPLRAMVLAMRQAGIPADISDTPGTLMCNHLMYGVLRY
VATHDLPPRVGWIHMPHLPEVAALDSNLGAPSMSLATSVAGVRVAVSATLEHASDVHAHVHSRLQI

Sequences:

>Translated_146_residues
MQDDLPDQTPPRGRIPQTDHNSTRALEDDLTDPNGPVAYWSTLPLRAMVLAMRQAGIPADISDTPGTLMCNHLMYGVLRY
VATHDLPPRVGWIHMPHLPEVAALDSNLGAPSMSLATSVAGVRVAVSATLEHASDVHAHVHSRLQI
>Mature_146_residues
MQDDLPDQTPPRGRIPQTDHNSTRALEDDLTDPNGPVAYWSTLPLRAMVLAMRQAGIPADISDTPGTLMCNHLMYGVLRY
VATHDLPPRVGWIHMPHLPEVAALDSNLGAPSMSLATSVAGVRVAVSATLEHASDVHAHVHSRLQI

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline [H]

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000816
- InterPro:   IPR016125 [H]

Pfam domain/function: PF01470 Peptidase_C15 [H]

EC number: =3.4.19.3 [H]

Molecular weight: Translated: 15808; Mature: 15808

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDDLPDQTPPRGRIPQTDHNSTRALEDDLTDPNGPVAYWSTLPLRAMVLAMRQAGIPAD
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCC
ISDTPGTLMCNHLMYGVLRYVATHDLPPRVGWIHMPHLPEVAALDSNLGAPSMSLATSVA
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHCCCCCCCCHHHHHHHH
GVRVAVSATLEHASDVHAHVHSRLQI
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQDDLPDQTPPRGRIPQTDHNSTRALEDDLTDPNGPVAYWSTLPLRAMVLAMRQAGIPAD
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCC
ISDTPGTLMCNHLMYGVLRYVATHDLPPRVGWIHMPHLPEVAALDSNLGAPSMSLATSVA
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHCCCCCCCCHHHHHHHH
GVRVAVSATLEHASDVHAHVHSRLQI
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]