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The map label for this gene is yegE [C]

Identifier: 158315074

GI number: 158315074

Start: 3872751

End: 3874409

Strand: Direct

Name: yegE [C]

Synonym: Franean1_3270

Alternate gene names: 158315074

Gene position: 3872751-3874409 (Clockwise)

Preceding gene: 158315072

Following gene: 158315075

Centisome position: 43.12

GC content: 68.78

Gene sequence:

>1659_bases
GTGTCTAGATTCCACGGTGCCATCGGCGCCGCGCCAGACCCGTGGCGTTCGACCAGTTCGGGCCGTATGCCACGGCTGTT
TCTGTGTGCCGTTGTCGCCGCCTTGGTGCTGCTGGGGCTGGATGTCGCCTTCGCTGTGCTACTGGACCCGCGACCCAGCC
GAATCGGTACAACTTTCGTCGACACTGCCACCGAGCTCGCTGCCGCGGCTGCCTGTTTCTGGACCGCTCGGCGGATGCGC
GGGGCGGAGCGTCGCTGGCGGCGGCTGATCGGCTTCGCGGCCAGCGGTGCGATGCTCACTGGCCTTGGGACGGCGGCGAT
GTTACTGGCCACTGGCTCGGTTGGCCCGCCGCCGGTCTATGCTGTCCTCATCCCGTGCTACGGGCTGGCGCTGGCCGGGC
TGCTCTCCCTGCCCACCGACCCGCTGGACGGCCGGGGCGGGAGCGCCGAGACGGTGCGGCACGGCGGGCTCCGTTGGTGC
GCGATCACCATGCTGGATTGCCTGCTGCTCGTCGGTTCGATCATCCTGCTGGAGTGGGTGACAGTGCTCACCGCGCTCGT
CCACGCGGGCGGGCACGACCCCGTACACTTCCTGTTCTCCCTGGTCCACGCGGTCGCCGGTCTGATCCTGGCTACGGCGG
TGCTGCTGATCGCAAGCTTCCGCCGGCCGCGCTCCCGCGGGACGTTGGCGTTACTTGGCACCGGCCTGCTGACCTACGGG
CTCACCAACAACATCCTCGTCTACCACACCGCGCAGGGCAGGATCTCCCTTCCACCGTGGAGCCTGATCGGGTTTGCTCT
GGCCTGGCTGCTGATACTCCTCGCCGCGCTCGTCCCGGTCCCGGCTCACCCGCAGGCCGACGGCCCGACGCCGGTTAGCC
AGCGGGTACTGTGGGCGCACGCCCTGCTGCCCTACGTCGTGCTCGGCGCGGTAAGCCTGCTGGTGCTGGGCAAACTGACC
ACCGGGACGCGGCTCGACCGGTTCGAGACATACGGCATGCTCGGCCTGCTGCTGGTGACGCTTGTCCGGCAGATGGTCAC
CTTGGCTGAGAACACCCGGCTGCTGGCTGCGGTGCGGGAACGGGAACAGCAGCTGCATTACCAGGCGTTCCACGACCAGC
TGACCGGCCTGCCGAACCGGGCGTTGTTCGCCCGACGGCTAGAACAGGCACTCGCACACAACCCCGACACCGACGACGTC
AGTGTCGGCACCCCGCTGTCGGTGATGTTCCTGGATCTCGACGAGTTCAAGGGGGTGAACGACGCATTCGGGCACGCCGC
CGGGGATGAACTCCTCAAGATCAGCGCAGAGCGGTTGCGGGCGGGGACGCGCGCCGCGGACACCGTAGCTCGGCTCGGCG
GTGACGAGTTCGCCGTCATCCTCGACGGCGGCGGACCAGACAATCCCCGCCAGATCGGCGAGCGGCTCGCCGCGGCAATC
CAGACCCCCTGCGTGCTCGCCGGACGGCCTTATACCCCGCGAGCCAGCCTTGGCCTGGTCATCCTGGACGGCTCCGCGGC
TCAGCCGCCCGGTCCCGACACCCTGCTGAACCAGGCCGACCGGGCGATGTACACAGCCAAGCGGGAACGGGCCGGCAGAC
TGGTGATCTACCGGCCAGACCTTGCCCCCACCGGCCACCACCGAACGACACGAATGTGA

Upstream 100 bases:

>100_bases
ATCGAACGCCGGGCCCGCCGCGCCGCCGGCCTCGGACCGGCAAGGCGTCGAATCGCCATGCGCGGCAGACGGGGCTAGCC
TCACTTGCAGGATTTATCTC

Downstream 100 bases:

>100_bases
CTTTACTAGTCATAAATGGCGCCATACGAGCGACCGGAAATAGGAGCGTTACCGGAGGCGGCAGGCCCACGACCTGAGCC
GCCTGTTTCCAGGCGAAGTC

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 552; Mature: 551

Protein sequence:

>552_residues
MSRFHGAIGAAPDPWRSTSSGRMPRLFLCAVVAALVLLGLDVAFAVLLDPRPSRIGTTFVDTATELAAAAACFWTARRMR
GAERRWRRLIGFAASGAMLTGLGTAAMLLATGSVGPPPVYAVLIPCYGLALAGLLSLPTDPLDGRGGSAETVRHGGLRWC
AITMLDCLLLVGSIILLEWVTVLTALVHAGGHDPVHFLFSLVHAVAGLILATAVLLIASFRRPRSRGTLALLGTGLLTYG
LTNNILVYHTAQGRISLPPWSLIGFALAWLLILLAALVPVPAHPQADGPTPVSQRVLWAHALLPYVVLGAVSLLVLGKLT
TGTRLDRFETYGMLGLLLVTLVRQMVTLAENTRLLAAVREREQQLHYQAFHDQLTGLPNRALFARRLEQALAHNPDTDDV
SVGTPLSVMFLDLDEFKGVNDAFGHAAGDELLKISAERLRAGTRAADTVARLGGDEFAVILDGGGPDNPRQIGERLAAAI
QTPCVLAGRPYTPRASLGLVILDGSAAQPPGPDTLLNQADRAMYTAKRERAGRLVIYRPDLAPTGHHRTTRM

Sequences:

>Translated_552_residues
MSRFHGAIGAAPDPWRSTSSGRMPRLFLCAVVAALVLLGLDVAFAVLLDPRPSRIGTTFVDTATELAAAAACFWTARRMR
GAERRWRRLIGFAASGAMLTGLGTAAMLLATGSVGPPPVYAVLIPCYGLALAGLLSLPTDPLDGRGGSAETVRHGGLRWC
AITMLDCLLLVGSIILLEWVTVLTALVHAGGHDPVHFLFSLVHAVAGLILATAVLLIASFRRPRSRGTLALLGTGLLTYG
LTNNILVYHTAQGRISLPPWSLIGFALAWLLILLAALVPVPAHPQADGPTPVSQRVLWAHALLPYVVLGAVSLLVLGKLT
TGTRLDRFETYGMLGLLLVTLVRQMVTLAENTRLLAAVREREQQLHYQAFHDQLTGLPNRALFARRLEQALAHNPDTDDV
SVGTPLSVMFLDLDEFKGVNDAFGHAAGDELLKISAERLRAGTRAADTVARLGGDEFAVILDGGGPDNPRQIGERLAAAI
QTPCVLAGRPYTPRASLGLVILDGSAAQPPGPDTLLNQADRAMYTAKRERAGRLVIYRPDLAPTGHHRTTRM
>Mature_551_residues
SRFHGAIGAAPDPWRSTSSGRMPRLFLCAVVAALVLLGLDVAFAVLLDPRPSRIGTTFVDTATELAAAAACFWTARRMRG
AERRWRRLIGFAASGAMLTGLGTAAMLLATGSVGPPPVYAVLIPCYGLALAGLLSLPTDPLDGRGGSAETVRHGGLRWCA
ITMLDCLLLVGSIILLEWVTVLTALVHAGGHDPVHFLFSLVHAVAGLILATAVLLIASFRRPRSRGTLALLGTGLLTYGL
TNNILVYHTAQGRISLPPWSLIGFALAWLLILLAALVPVPAHPQADGPTPVSQRVLWAHALLPYVVLGAVSLLVLGKLTT
GTRLDRFETYGMLGLLLVTLVRQMVTLAENTRLLAAVREREQQLHYQAFHDQLTGLPNRALFARRLEQALAHNPDTDDVS
VGTPLSVMFLDLDEFKGVNDAFGHAAGDELLKISAERLRAGTRAADTVARLGGDEFAVILDGGGPDNPRQIGERLAAAIQ
TPCVLAGRPYTPRASLGLVILDGSAAQPPGPDTLLNQADRAMYTAKRERAGRLVIYRPDLAPTGHHRTTRM

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=191, Percent_Identity=36.1256544502618, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI87082007, Length=196, Percent_Identity=33.6734693877551, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI145693134, Length=172, Percent_Identity=31.9767441860465, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI87081977, Length=195, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788956, Length=177, Percent_Identity=36.7231638418079, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1787541, Length=183, Percent_Identity=30.0546448087432, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87081881, Length=176, Percent_Identity=31.25, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787262, Length=236, Percent_Identity=27.1186440677966, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1787816, Length=169, Percent_Identity=31.9526627218935, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1786584, Length=178, Percent_Identity=29.2134831460674, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87081974, Length=206, Percent_Identity=29.126213592233, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788085, Length=181, Percent_Identity=27.0718232044199, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 58925; Mature: 58793

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRFHGAIGAAPDPWRSTSSGRMPRLFLCAVVAALVLLGLDVAFAVLLDPRPSRIGTTFV
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
DTATELAAAAACFWTARRMRGAERRWRRLIGFAASGAMLTGLGTAAMLLATGSVGPPPVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHH
AVLIPCYGLALAGLLSLPTDPLDGRGGSAETVRHGGLRWCAITMLDCLLLVGSIILLEWV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
TVLTALVHAGGHDPVHFLFSLVHAVAGLILATAVLLIASFRRPRSRGTLALLGTGLLTYG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHC
LTNNILVYHTAQGRISLPPWSLIGFALAWLLILLAALVPVPAHPQADGPTPVSQRVLWAH
CCCCEEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
ALLPYVVLGAVSLLVLGKLTTGTRLDRFETYGMLGLLLVTLVRQMVTLAENTRLLAAVRE
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
REQQLHYQAFHDQLTGLPNRALFARRLEQALAHNPDTDDVSVGTPLSVMFLDLDEFKGVN
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHCCCC
DAFGHAAGDELLKISAERLRAGTRAADTVARLGGDEFAVILDGGGPDNPRQIGERLAAAI
HHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHH
QTPCVLAGRPYTPRASLGLVILDGSAAQPPGPDTLLNQADRAMYTAKRERAGRLVIYRPD
CCCEEECCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCC
LAPTGHHRTTRM
CCCCCCCCCCCC
>Mature Secondary Structure 
SRFHGAIGAAPDPWRSTSSGRMPRLFLCAVVAALVLLGLDVAFAVLLDPRPSRIGTTFV
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
DTATELAAAAACFWTARRMRGAERRWRRLIGFAASGAMLTGLGTAAMLLATGSVGPPPVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHH
AVLIPCYGLALAGLLSLPTDPLDGRGGSAETVRHGGLRWCAITMLDCLLLVGSIILLEWV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
TVLTALVHAGGHDPVHFLFSLVHAVAGLILATAVLLIASFRRPRSRGTLALLGTGLLTYG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHC
LTNNILVYHTAQGRISLPPWSLIGFALAWLLILLAALVPVPAHPQADGPTPVSQRVLWAH
CCCCEEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
ALLPYVVLGAVSLLVLGKLTTGTRLDRFETYGMLGLLLVTLVRQMVTLAENTRLLAAVRE
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
REQQLHYQAFHDQLTGLPNRALFARRLEQALAHNPDTDDVSVGTPLSVMFLDLDEFKGVN
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHCCCC
DAFGHAAGDELLKISAERLRAGTRAADTVARLGGDEFAVILDGGGPDNPRQIGERLAAAI
HHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHH
QTPCVLAGRPYTPRASLGLVILDGSAAQPPGPDTLLNQADRAMYTAKRERAGRLVIYRPD
CCCEEECCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCC
LAPTGHHRTTRM
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]