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The map label for this gene is cocE [H]

Identifier: 158315046

GI number: 158315046

Start: 3830032

End: 3831795

Strand: Direct

Name: cocE [H]

Synonym: Franean1_3241

Alternate gene names: 158315046

Gene position: 3830032-3831795 (Clockwise)

Preceding gene: 158315034

Following gene: 158315050

Centisome position: 42.64

GC content: 70.01

Gene sequence:

>1764_bases
TTGATCGCCGAAGAGGAGCTGATCGTCGAGAAGGGCGTCATGGTTCCGATGCGCGACGGTGTGCGCCTGTACACGGACAT
CTACCGGCCGGCCGGTCCCGGGCCGTTTCCTGTGCTTGTGTCCCGTACCGCCTACTGGCTCAACGGCGGGGTCACCCAGG
GCCTGAGCGGTTTCGCCAAACTGGTCGCCCGGCAGGGCTATGTGGCCGTGTTCCAGCAGAGTCGCGGCCGGTTCGCTTCC
GAGGGTGTGTTCCACCCGGCGCTGTGCGACGTGGACGACGGGTACGACGTGGTGGAGTGGGCGGCCGCCCAGCCGTGGTC
CACCGGCAAGGTCGGTATGTTCGGCGGGTCGTACCAGGGGCTCACCCAGTGGGCGGCCGCCATCGCCCGGCCACCGCATC
TCGCGTGCATCGCGCCGTTGACGTCCACCTGGAACACCTTCGGCAATGAGATCTGGTACGCCGCGCCGGGCGTCCTGTCG
CTGGGCAGCGCGTTCGCGTGGGCGTGGGGCGCGGTGCTCGGCGAGGCCGAGCGCCGGGGCGTTCCGGCGCCGGAGGGCGC
GATCCACCACGGTGAGGAGGGCAACGAGCCCGGGGACGTCGCGGAGGCCATCGCGAAGCGCACCGTGGCGATGATGGAGA
TGTACGCCTTCCGCCCGCTGCGCGACGCGCCCCAGCTCGAGCTGGTGTCGTGGTGGAAGGACTGGTGCGACAACGGCGAC
CCGAACGACCCGTACTGGCTGGTGGTCAACGCCTCGGAGCACGCCGTCGACCTCGACCTGCCGATCTTCCAGGCGAGTGG
CTGGTACGACATGTTCCTCAACGGGACGCTCGAAGCCTTCCAGGCGCTGCGCGGCGCGGGCGCCACCCAGTACGTCCGGG
ACAACCAGGAGTTGGTCATCGGACCGTGGAACCACGGCGGCGTGTGCCCGCCCCGTCCGGACGCACCGGCGGACACCGGG
CCCCTGGGGCTCTGGGACCTCTCCGAGGGTTCCGCCTGCATGGAGTTCTTCCGCCGTCACCTGAAGGGCGAGCAGGTCCT
GGACCCCGCGCCGGTCCGCCTGTTCGTCATGGGCGAGAACATCTGGCGCGACGAGCGGGAATGGCCGCTGGCCCGCACCC
GCTGGACGCCCTACTACCTGCACAGTGCCGGCGGGGCCAACACCGCCGCGGGCGACGGCTCGCTGTCCACGGAGCGTCCC
GGTGACCAGCCGGACGACGTCTTCGTCTACGACCCGCAGAACCCGGTCGTGTCGCAGGGCCGGCTGGAGTGCTACGCCCC
CGACCACGGCGCCGAGACCGCCCGCAACGAGAGCCGCGACGACGTTCTCGTCTACACCACGTCACCGCTCGAGCATGACC
TGGAGGTCACCGGCCCGGTGACGCTCGAGCTCTGGGCGTCGTCGTCCGTCTCCGACACCGACTTCACCGCGAAGCTCGTC
GATGTCTTCCCGGACGGCGCGGCCATACCGCTCGCCGAGGGCGTGGTGCGGACAGGCGTGGCGTTCACGCAGCCACCGCG
GCCCGAGACGCCGCGTCGTTACCGAATCAGTCTCTGGGCGACGAGCAACGTCTTCAGATCCGGTCACCGTATCCGGCTCG
ACGTCTCGTCGAGCGCGTTCCCGGAGTACGAGCTGAACCCGAATACCGGTCAGCGGATCACCCACGACGCCACCGGGAAG
ACGGTGCCCGCGACGCAGCGGGTGCACCATGACCGCCGCTTTCCTTCACGCCTTGTCCTGCCGGTGATCCCGCGGCCCGC
GTAG

Upstream 100 bases:

>100_bases
CTCGGACCGTCCACCGCGCCCCACCGCTCCGTCGCGCCCGCATTCACCTGTGATCCCACGCATGGACCGCTGTCTGATCG
CCGCACCAGGAGGTTGAGAG

Downstream 100 bases:

>100_bases
CGGGGCAGTCCGCGCGGGGGCCGGCGGAGGGCGTGGGTGCCCCCGAGGGGTGACCGCCTCGAGGCTGCCGCCGAACGGCG
TGTCCGGGTTACGGCGTATC

Product: X-Pro dipeptidyl-peptidase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 587; Mature: 587

Protein sequence:

>587_residues
MIAEEELIVEKGVMVPMRDGVRLYTDIYRPAGPGPFPVLVSRTAYWLNGGVTQGLSGFAKLVARQGYVAVFQQSRGRFAS
EGVFHPALCDVDDGYDVVEWAAAQPWSTGKVGMFGGSYQGLTQWAAAIARPPHLACIAPLTSTWNTFGNEIWYAAPGVLS
LGSAFAWAWGAVLGEAERRGVPAPEGAIHHGEEGNEPGDVAEAIAKRTVAMMEMYAFRPLRDAPQLELVSWWKDWCDNGD
PNDPYWLVVNASEHAVDLDLPIFQASGWYDMFLNGTLEAFQALRGAGATQYVRDNQELVIGPWNHGGVCPPRPDAPADTG
PLGLWDLSEGSACMEFFRRHLKGEQVLDPAPVRLFVMGENIWRDEREWPLARTRWTPYYLHSAGGANTAAGDGSLSTERP
GDQPDDVFVYDPQNPVVSQGRLECYAPDHGAETARNESRDDVLVYTTSPLEHDLEVTGPVTLELWASSSVSDTDFTAKLV
DVFPDGAAIPLAEGVVRTGVAFTQPPRPETPRRYRISLWATSNVFRSGHRIRLDVSSSAFPEYELNPNTGQRITHDATGK
TVPATQRVHHDRRFPSRLVLPVIPRPA

Sequences:

>Translated_587_residues
MIAEEELIVEKGVMVPMRDGVRLYTDIYRPAGPGPFPVLVSRTAYWLNGGVTQGLSGFAKLVARQGYVAVFQQSRGRFAS
EGVFHPALCDVDDGYDVVEWAAAQPWSTGKVGMFGGSYQGLTQWAAAIARPPHLACIAPLTSTWNTFGNEIWYAAPGVLS
LGSAFAWAWGAVLGEAERRGVPAPEGAIHHGEEGNEPGDVAEAIAKRTVAMMEMYAFRPLRDAPQLELVSWWKDWCDNGD
PNDPYWLVVNASEHAVDLDLPIFQASGWYDMFLNGTLEAFQALRGAGATQYVRDNQELVIGPWNHGGVCPPRPDAPADTG
PLGLWDLSEGSACMEFFRRHLKGEQVLDPAPVRLFVMGENIWRDEREWPLARTRWTPYYLHSAGGANTAAGDGSLSTERP
GDQPDDVFVYDPQNPVVSQGRLECYAPDHGAETARNESRDDVLVYTTSPLEHDLEVTGPVTLELWASSSVSDTDFTAKLV
DVFPDGAAIPLAEGVVRTGVAFTQPPRPETPRRYRISLWATSNVFRSGHRIRLDVSSSAFPEYELNPNTGQRITHDATGK
TVPATQRVHHDRRFPSRLVLPVIPRPA
>Mature_587_residues
MIAEEELIVEKGVMVPMRDGVRLYTDIYRPAGPGPFPVLVSRTAYWLNGGVTQGLSGFAKLVARQGYVAVFQQSRGRFAS
EGVFHPALCDVDDGYDVVEWAAAQPWSTGKVGMFGGSYQGLTQWAAAIARPPHLACIAPLTSTWNTFGNEIWYAAPGVLS
LGSAFAWAWGAVLGEAERRGVPAPEGAIHHGEEGNEPGDVAEAIAKRTVAMMEMYAFRPLRDAPQLELVSWWKDWCDNGD
PNDPYWLVVNASEHAVDLDLPIFQASGWYDMFLNGTLEAFQALRGAGATQYVRDNQELVIGPWNHGGVCPPRPDAPADTG
PLGLWDLSEGSACMEFFRRHLKGEQVLDPAPVRLFVMGENIWRDEREWPLARTRWTPYYLHSAGGANTAAGDGSLSTERP
GDQPDDVFVYDPQNPVVSQGRLECYAPDHGAETARNESRDDVLVYTTSPLEHDLEVTGPVTLELWASSSVSDTDFTAKLV
DVFPDGAAIPLAEGVVRTGVAFTQPPRPETPRRYRISLWATSNVFRSGHRIRLDVSSSAFPEYELNPNTGQRITHDATGK
TVPATQRVHHDRRFPSRLVLPVIPRPA

Specific function: Hydrolyzes cocaine to benzoate and ecgonine methyl ester, endowing the bacteria with the ability to utilize cocaine as a sole source of carbon and energy for growth, as this bacterium lives in the rhizosphere of coca plants [H]

COG id: COG2936

COG function: function code R; Predicted acyl esterases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha/beta hydrolase family. Carboxylesterase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005674
- InterPro:   IPR008979
- InterPro:   IPR013736
- InterPro:   IPR000383 [H]

Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C [H]

EC number: NA

Molecular weight: Translated: 64519; Mature: 64519

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAEEELIVEKGVMVPMRDGVRLYTDIYRPAGPGPFPVLVSRTAYWLNGGVTQGLSGFAK
CCCCHHHHHHCCCEEECCCCEEEEHHHHCCCCCCCCHHEEECEEEEECCCHHHHHHHHHH
LVARQGYVAVFQQSRGRFASEGVFHPALCDVDDGYDVVEWAAAQPWSTGKVGMFGGSYQG
HHHCCCHHEEEHHHCCCCCCCCCCCCEECCCCCCCCHHHHHCCCCCCCCCEEECCCCCHH
LTQWAAAIARPPHLACIAPLTSTWNTFGNEIWYAAPGVLSLGSAFAWAWGAVLGEAERRG
HHHHHHHHCCCCCEEEEECCHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
VPAPEGAIHHGEEGNEPGDVAEAIAKRTVAMMEMYAFRPLRDAPQLELVSWWKDWCDNGD
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCC
PNDPYWLVVNASEHAVDLDLPIFQASGWYDMFLNGTLEAFQALRGAGATQYVRDNQELVI
CCCCEEEEEECCCCEEEECCEEEECCCCEEEEECCHHHHHHHHHCCCCCCEEECCCEEEE
GPWNHGGVCPPRPDAPADTGPLGLWDLSEGSACMEFFRRHLKGEQVLDPAPVRLFVMGEN
ECCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCC
IWRDEREWPLARTRWTPYYLHSAGGANTAAGDGSLSTERPGDQPDDVFVYDPQNPVVSQG
CCCCCCCCCCHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCC
RLECYAPDHGAETARNESRDDVLVYTTSPLEHDLEVTGPVTLELWASSSVSDTDFTAKLV
CEEEECCCCCCHHHCCCCCCCEEEEECCCCCCCCEECCCEEEEEECCCCCCCCCHHEEEE
DVFPDGAAIPLAEGVVRTGVAFTQPPRPETPRRYRISLWATSNVFRSGHRIRLDVSSSAF
ECCCCCCCCCHHHHHHHCCCEECCCCCCCCCCEEEEEEEEECHHHHCCCEEEEEECCCCC
PEYELNPNTGQRITHDATGKTVPATQRVHHDRRFPSRLVLPVIPRPA
CCEECCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCCEEEECCCCCC
>Mature Secondary Structure
MIAEEELIVEKGVMVPMRDGVRLYTDIYRPAGPGPFPVLVSRTAYWLNGGVTQGLSGFAK
CCCCHHHHHHCCCEEECCCCEEEEHHHHCCCCCCCCHHEEECEEEEECCCHHHHHHHHHH
LVARQGYVAVFQQSRGRFASEGVFHPALCDVDDGYDVVEWAAAQPWSTGKVGMFGGSYQG
HHHCCCHHEEEHHHCCCCCCCCCCCCEECCCCCCCCHHHHHCCCCCCCCCEEECCCCCHH
LTQWAAAIARPPHLACIAPLTSTWNTFGNEIWYAAPGVLSLGSAFAWAWGAVLGEAERRG
HHHHHHHHCCCCCEEEEECCHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
VPAPEGAIHHGEEGNEPGDVAEAIAKRTVAMMEMYAFRPLRDAPQLELVSWWKDWCDNGD
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCC
PNDPYWLVVNASEHAVDLDLPIFQASGWYDMFLNGTLEAFQALRGAGATQYVRDNQELVI
CCCCEEEEEECCCCEEEECCEEEECCCCEEEEECCHHHHHHHHHCCCCCCEEECCCEEEE
GPWNHGGVCPPRPDAPADTGPLGLWDLSEGSACMEFFRRHLKGEQVLDPAPVRLFVMGEN
ECCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCC
IWRDEREWPLARTRWTPYYLHSAGGANTAAGDGSLSTERPGDQPDDVFVYDPQNPVVSQG
CCCCCCCCCCHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCC
RLECYAPDHGAETARNESRDDVLVYTTSPLEHDLEVTGPVTLELWASSSVSDTDFTAKLV
CEEEECCCCCCHHHCCCCCCCEEEEECCCCCCCCEECCCEEEEEECCCCCCCCCHHEEEE
DVFPDGAAIPLAEGVVRTGVAFTQPPRPETPRRYRISLWATSNVFRSGHRIRLDVSSSAF
ECCCCCCCCCHHHHHHHCCCEECCCCCCCCCCEEEEEEEEECHHHHCCCEEEEEECCCCC
PEYELNPNTGQRITHDATGKTVPATQRVHHDRRFPSRLVLPVIPRPA
CCEECCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10698749; 11742345; 12369817 [H]