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The map label for this gene is yngJ [H]

Identifier: 158314543

GI number: 158314543

Start: 3218335

End: 3219624

Strand: Direct

Name: yngJ [H]

Synonym: Franean1_2719

Alternate gene names: 158314543

Gene position: 3218335-3219624 (Clockwise)

Preceding gene: 158314542

Following gene: 158314544

Centisome position: 35.83

GC content: 71.16

Gene sequence:

>1290_bases
GTGAGTATCGACGAGACCGAGTCGGTCGAGGACTTCCGGAACCGTGTGCGGAGCTGGCTGGCGGAGAACATGCCGCGCAC
CGTGCCGGGCGCCCCTGGCCGGCTGACCGTCCGCTCGGACGAGGAGGAGCTGGCCGAGGTCGCGGAGGAACGGCGGCTGC
AGCGGTTGCTGTGGGATGGCGGGTTCGCCGGCATCTGCTTCCCGAGGGAGTACGGCGGCCTGGGGCTGACACCCGCGCAC
GCCGAGGCCTTCAACGAGGAGATCGCCGGCTACCGGTACCCGTCGCGCCTGCAGGTTCCGACCATGACGCCCTGCGCGGC
GGTGATCCTCGAGTTCGGGACCCGCGAGCAGAAGCTCCGGCACCTCCCGGCGATCCTGCGGGGTGAGGAGCTGTGGATGC
AGTTCCTGTCCGAGCCGGGATCGGGTTCGGACGTCGCGGGAGCGAAGACGAGCGCGGTGCGTGACGGTGACGACTGGGTG
ATCAACGGCTCCAAGATCTGGACGACCGGCGCGTGGTGGTCGGACTGGGGGCTCTGCCTGGCCCGCACCAACTGGGATGT
GCCCAAGCACCGCGGGCTCACCGTGTTCATGCTCCCGATCCACGAGCCCGGGATCGAGATCTCCCGGATCGAGATGCTCG
ACGGCAACAAGGAGTTCTGCCAGGAGTACCTGACCGACGTACGGGTGGCCGACAGCGCCCGGGTCGGCGGTGTCGACGAC
GGCTGGACCGTGGTCACCCGCTGGCTGTTCCACGAGCGCTCCTTCAGCTCCTCACCGCTTGCTGTCCGCCCGGCCGGCGG
CGGGGGAGAGCCGGCCGGTGACCCCGGCCCCGCCCTGCTGGCGCTCGCCGAGCAGGCTGGTCGGCTCGGTGATCCGCGGG
CGCGTGAGCTGGTCGGGGAGGCGCACACGCTGAAGGTCGCGATGCGGGAGCTCGACCGGAGACTGCACGCCCTCATCACA
GCCGGGAAGGCCTCGGACCATCTGGCGGCCGTCGGCCGGTTGATGCACGGCGTAGCGGCGGCGCAGCTGGCGACCATCGC
CTTCGACCTGGCCGGCCCGACCGCGGTGGCCAGCGGCGAGGACGAGGACGTGCTGGGCGGTCAGGGCATGAGGTTCCTGC
TGCGTCAGATCGCCTCGATCGGCGGTGGCACGACGGAGATGGCCCGCAACGTCATCAGTGAACGCGTCCTGGGGATGCCG
CGCGAGCAGAGCCTGGACCGGAACGTGCCCTACCGGGACGTGCGCACCGCACCCTCCTCCGGCGGACCGCGGACGGGCCG
CCGTCCCTGA

Upstream 100 bases:

>100_bases
GGGTGGTCCTCGCGAGTGCGCTTCTGGGCACCGTGCGGGAACACCGCCTGCGGATCGCCACCCTTCTCGAAGCCGGGAAC
AGCGTGGGAGAGGCCGGAGC

Downstream 100 bases:

>100_bases
CCTCTGCCTATTGTCAAAGTCGACCTCGATGTTAATGTCGGTGCGCCGACGATACGGGGCCCTGCCTGCCGTCGTGTCCG
GGTCTGGCCGTGGGCGGCGG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MSIDETESVEDFRNRVRSWLAENMPRTVPGAPGRLTVRSDEEELAEVAEERRLQRLLWDGGFAGICFPREYGGLGLTPAH
AEAFNEEIAGYRYPSRLQVPTMTPCAAVILEFGTREQKLRHLPAILRGEELWMQFLSEPGSGSDVAGAKTSAVRDGDDWV
INGSKIWTTGAWWSDWGLCLARTNWDVPKHRGLTVFMLPIHEPGIEISRIEMLDGNKEFCQEYLTDVRVADSARVGGVDD
GWTVVTRWLFHERSFSSSPLAVRPAGGGGEPAGDPGPALLALAEQAGRLGDPRARELVGEAHTLKVAMRELDRRLHALIT
AGKASDHLAAVGRLMHGVAAAQLATIAFDLAGPTAVASGEDEDVLGGQGMRFLLRQIASIGGGTTEMARNVISERVLGMP
REQSLDRNVPYRDVRTAPSSGGPRTGRRP

Sequences:

>Translated_429_residues
MSIDETESVEDFRNRVRSWLAENMPRTVPGAPGRLTVRSDEEELAEVAEERRLQRLLWDGGFAGICFPREYGGLGLTPAH
AEAFNEEIAGYRYPSRLQVPTMTPCAAVILEFGTREQKLRHLPAILRGEELWMQFLSEPGSGSDVAGAKTSAVRDGDDWV
INGSKIWTTGAWWSDWGLCLARTNWDVPKHRGLTVFMLPIHEPGIEISRIEMLDGNKEFCQEYLTDVRVADSARVGGVDD
GWTVVTRWLFHERSFSSSPLAVRPAGGGGEPAGDPGPALLALAEQAGRLGDPRARELVGEAHTLKVAMRELDRRLHALIT
AGKASDHLAAVGRLMHGVAAAQLATIAFDLAGPTAVASGEDEDVLGGQGMRFLLRQIASIGGGTTEMARNVISERVLGMP
REQSLDRNVPYRDVRTAPSSGGPRTGRRP
>Mature_428_residues
SIDETESVEDFRNRVRSWLAENMPRTVPGAPGRLTVRSDEEELAEVAEERRLQRLLWDGGFAGICFPREYGGLGLTPAHA
EAFNEEIAGYRYPSRLQVPTMTPCAAVILEFGTREQKLRHLPAILRGEELWMQFLSEPGSGSDVAGAKTSAVRDGDDWVI
NGSKIWTTGAWWSDWGLCLARTNWDVPKHRGLTVFMLPIHEPGIEISRIEMLDGNKEFCQEYLTDVRVADSARVGGVDDG
WTVVTRWLFHERSFSSSPLAVRPAGGGGEPAGDPGPALLALAEQAGRLGDPRARELVGEAHTLKVAMRELDRRLHALITA
GKASDHLAAVGRLMHGVAAAQLATIAFDLAGPTAVASGEDEDVLGGQGMRFLLRQIASIGGGTTEMARNVISERVLGMPR
EQSLDRNVPYRDVRTAPSSGGPRTGRRP

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557231, Length=357, Percent_Identity=26.0504201680672, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI187960098, Length=357, Percent_Identity=26.0504201680672, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI4557233, Length=178, Percent_Identity=30.8988764044944, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI7656849, Length=318, Percent_Identity=28.6163522012579, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI226958414, Length=409, Percent_Identity=25.9168704156479, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI226958412, Length=371, Percent_Identity=26.1455525606469, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI4501857, Length=253, Percent_Identity=26.4822134387352, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4501859, Length=197, Percent_Identity=30.9644670050761, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1786223, Length=370, Percent_Identity=24.3243243243243, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081958, Length=210, Percent_Identity=27.6190476190476, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508101, Length=196, Percent_Identity=34.1836734693878, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17534899, Length=193, Percent_Identity=35.2331606217617, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71990804, Length=196, Percent_Identity=34.1836734693878, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17569725, Length=350, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17506239, Length=197, Percent_Identity=30.4568527918782, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17538396, Length=225, Percent_Identity=31.1111111111111, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=190, Percent_Identity=31.0526315789474, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17505929, Length=208, Percent_Identity=29.3269230769231, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17570075, Length=342, Percent_Identity=26.9005847953216, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17551932, Length=191, Percent_Identity=29.8429319371728, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17533517, Length=151, Percent_Identity=27.8145695364238, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24646207, Length=212, Percent_Identity=31.6037735849057, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24660351, Length=195, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21356377, Length=198, Percent_Identity=29.2929292929293, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24666513, Length=246, Percent_Identity=26.8292682926829, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI21355753, Length=363, Percent_Identity=26.9972451790634, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 46776; Mature: 46645

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDETESVEDFRNRVRSWLAENMPRTVPGAPGRLTVRSDEEELAEVAEERRLQRLLWDG
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCC
GFAGICFPREYGGLGLTPAHAEAFNEEIAGYRYPSRLQVPTMTPCAAVILEFGTREQKLR
CCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHH
HLPAILRGEELWMQFLSEPGSGSDVAGAKTSAVRDGDDWVINGSKIWTTGAWWSDWGLCL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCEEEECCCCCCCCCEEE
ARTNWDVPKHRGLTVFMLPIHEPGIEISRIEMLDGNKEFCQEYLTDVRVADSARVGGVDD
EECCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHECCCCCCCCCCCC
GWTVVTRWLFHERSFSSSPLAVRPAGGGGEPAGDPGPALLALAEQAGRLGDPRARELVGE
CHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
AHTLKVAMRELDRRLHALITAGKASDHLAAVGRLMHGVAAAQLATIAFDLAGPTAVASGE
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCC
DEDVLGGQGMRFLLRQIASIGGGTTEMARNVISERVLGMPREQSLDRNVPYRDVRTAPSS
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHCCCCCC
GGPRTGRRP
CCCCCCCCC
>Mature Secondary Structure 
SIDETESVEDFRNRVRSWLAENMPRTVPGAPGRLTVRSDEEELAEVAEERRLQRLLWDG
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCC
GFAGICFPREYGGLGLTPAHAEAFNEEIAGYRYPSRLQVPTMTPCAAVILEFGTREQKLR
CCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHH
HLPAILRGEELWMQFLSEPGSGSDVAGAKTSAVRDGDDWVINGSKIWTTGAWWSDWGLCL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCEEEECCCCCCCCCEEE
ARTNWDVPKHRGLTVFMLPIHEPGIEISRIEMLDGNKEFCQEYLTDVRVADSARVGGVDD
EECCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHECCCCCCCCCCCC
GWTVVTRWLFHERSFSSSPLAVRPAGGGGEPAGDPGPALLALAEQAGRLGDPRARELVGE
CHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
AHTLKVAMRELDRRLHALITAGKASDHLAAVGRLMHGVAAAQLATIAFDLAGPTAVASGE
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCC
DEDVLGGQGMRFLLRQIASIGGGTTEMARNVISERVLGMPREQSLDRNVPYRDVRTAPSS
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHCCCCCC
GGPRTGRRP
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]