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The map label for this gene is yhaU [H]

Identifier: 158314058

GI number: 158314058

Start: 2661432

End: 2662646

Strand: Direct

Name: yhaU [H]

Synonym: Franean1_2225

Alternate gene names: 158314058

Gene position: 2661432-2662646 (Clockwise)

Preceding gene: 158314057

Following gene: 158314059

Centisome position: 29.63

GC content: 72.26

Gene sequence:

>1215_bases
GTGCACGACACGGCGAGGATCTTCCTCGAGCTGGGCGCGGTGCTGTTCGCACTGGGAGTGCTCGGCCATTTCGCGTTGCG
GGTCGGTATCTCACCGATTCCGCTGTACCTCATCGGTGGTCTCGCCTTCGGGCACGGCGGTGTCCTGCCGCTGGGCGCCA
GCGAGGACTTCATCGAGATCGGCGCCGAGATCGGTGTCATCCTCCTGCTGCTGACACTCGGCCTGGAGTACACCGCCGAG
GAGCTCCTGCACGGCCTGCGAAGACAGGCCCCGGCCGGGGTGCTCGACCTGACGCTCAACGCCGTCCCCGGCGTGGCGGC
CGCGTTCCTGCTCGGCTGGGGGCCGCTGGCGGCGGTGGTCATGGGCGGCGTCACCGCGATCTCCTCGTCCGGGATCATCG
CCAAGGTCCTGGGGGATCTGGGCCGCATCGGTAACCGGGAGACCCCGGTCGTGCTGTCGGTGCTCGTGCTCGAGGACCTC
GCGATGGCCGTCTACCTGCCGGTGGTCACCGCGCTGCTGGCCCATCACACCTTCGCCCGGGGCTCGCTGACCGTCGCGGT
GGCGCTGGGCGCGCTCGTCGCCGTCCTGTACGTCGCGCTGCGGCACAGCGACAAGGTCACCCTGCTCGTCTTCAGCCCGA
ACGTGGACCGCAACGACGAGGTCCTGCTGCTGCGGTCGCTGGGGCTGACCCTGCTCGTCGCCGGCGTCGCCCAGCGCATG
CAGGTCTCCGCCGCGGTCGGCGCGTTCCTGGTCGGCATCGCACTGTCCGGGCCGGTCGCGGAGGGCGCGCACGAGGTGCT
GATGCCGCTGCGCGACCTGTTCGCCGCCGTGTTCTTCGTGTTCTTCGGCCTGCAGACCGATCCGGTCGAGATCCCGCCCG
TGCTGCTCGCCGCGTCCCTGCTCGCGCTCGCCGGCGTGGCGACGAAGATCGTGACCGGATGGTGGGCCGCGCGGCGCGCG
GGCATCGCGACGATGGGCCGCTACCGCGCCGGCGCCGCGCTGGTCGCCCGCGGCGAGTTCTCGATCGTCATCGCCGGGCT
GGCGGTCGCCGCCGGAGTGAACCCGCAGCTCGGGCCGCTGGCCGCGTGCTACGTCCTGCTGATGGCGGTACTCGGCCCGC
TGGCGGCGCGGTTCGTCGAACCGGTCGTGCGAACGATCCGCCGCTGGTCACGGGCCCGCAGGCCACCGGATCCCGCCACC
GCGCGCGGCGCGTGA

Upstream 100 bases:

>100_bases
CCCCGGGGACGTCGTGGTCGTCGTCGGTACCCCGGAGAACACCGCCGCCGTCGCCCAGCTGCTGCGCGCTGGCTGACGGG
GAACGGGCGACCGACGACAC

Downstream 100 bases:

>100_bases
CCGCCTTGCCGCGGGCCGTGTGACCCGCGGCTGGGTGCCGGCGCGCGAATCTCGGCCGGGCTGGCGGGATTCACCCGGCG
ATGTTTGGCAGGATGACGCT

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MHDTARIFLELGAVLFALGVLGHFALRVGISPIPLYLIGGLAFGHGGVLPLGASEDFIEIGAEIGVILLLLTLGLEYTAE
ELLHGLRRQAPAGVLDLTLNAVPGVAAAFLLGWGPLAAVVMGGVTAISSSGIIAKVLGDLGRIGNRETPVVLSVLVLEDL
AMAVYLPVVTALLAHHTFARGSLTVAVALGALVAVLYVALRHSDKVTLLVFSPNVDRNDEVLLLRSLGLTLLVAGVAQRM
QVSAAVGAFLVGIALSGPVAEGAHEVLMPLRDLFAAVFFVFFGLQTDPVEIPPVLLAASLLALAGVATKIVTGWWAARRA
GIATMGRYRAGAALVARGEFSIVIAGLAVAAGVNPQLGPLAACYVLLMAVLGPLAARFVEPVVRTIRRWSRARRPPDPAT
ARGA

Sequences:

>Translated_404_residues
MHDTARIFLELGAVLFALGVLGHFALRVGISPIPLYLIGGLAFGHGGVLPLGASEDFIEIGAEIGVILLLLTLGLEYTAE
ELLHGLRRQAPAGVLDLTLNAVPGVAAAFLLGWGPLAAVVMGGVTAISSSGIIAKVLGDLGRIGNRETPVVLSVLVLEDL
AMAVYLPVVTALLAHHTFARGSLTVAVALGALVAVLYVALRHSDKVTLLVFSPNVDRNDEVLLLRSLGLTLLVAGVAQRM
QVSAAVGAFLVGIALSGPVAEGAHEVLMPLRDLFAAVFFVFFGLQTDPVEIPPVLLAASLLALAGVATKIVTGWWAARRA
GIATMGRYRAGAALVARGEFSIVIAGLAVAAGVNPQLGPLAACYVLLMAVLGPLAARFVEPVVRTIRRWSRARRPPDPAT
ARGA
>Mature_404_residues
MHDTARIFLELGAVLFALGVLGHFALRVGISPIPLYLIGGLAFGHGGVLPLGASEDFIEIGAEIGVILLLLTLGLEYTAE
ELLHGLRRQAPAGVLDLTLNAVPGVAAAFLLGWGPLAAVVMGGVTAISSSGIIAKVLGDLGRIGNRETPVVLSVLVLEDL
AMAVYLPVVTALLAHHTFARGSLTVAVALGALVAVLYVALRHSDKVTLLVFSPNVDRNDEVLLLRSLGLTLLVAGVAQRM
QVSAAVGAFLVGIALSGPVAEGAHEVLMPLRDLFAAVFFVFFGLQTDPVEIPPVLLAASLLALAGVATKIVTGWWAARRA
GIATMGRYRAGAALVARGEFSIVIAGLAVAAGVNPQLGPLAACYVLLMAVLGPLAARFVEPVVRTIRRWSRARRPPDPAT
ARGA

Specific function: Potassium/proton antiporter that mediates the efflux of potassium ions from the cell. Potassium antiport activity requires the presence of khtT. Has higher activity at alkaline pH. Can also mediate rubidium/proton antiport. Has no permeability for sodium

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Escherichia coli, GI1786685, Length=372, Percent_Identity=27.1505376344086, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 41844; Mature: 41844

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDTARIFLELGAVLFALGVLGHFALRVGISPIPLYLIGGLAFGHGGVLPLGASEDFIEI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCCCHHHHHH
GAEIGVILLLLTLGLEYTAEELLHGLRRQAPAGVLDLTLNAVPGVAAAFLLGWGPLAAVV
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEHHHHHCHHHHHHHHHHHHHHHHHH
MGGVTAISSSGIIAKVLGDLGRIGNRETPVVLSVLVLEDLAMAVYLPVVTALLAHHTFAR
HCCHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSLTVAVALGALVAVLYVALRHSDKVTLLVFSPNVDRNDEVLLLRSLGLTLLVAGVAQRM
CHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHH
QVSAAVGAFLVGIALSGPVAEGAHEVLMPLRDLFAAVFFVFFGLQTDPVEIPPVLLAASL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LALAGVATKIVTGWWAARRAGIATMGRYRAGAALVARGEFSIVIAGLAVAAGVNPQLGPL
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCCHHH
AACYVLLMAVLGPLAARFVEPVVRTIRRWSRARRPPDPATARGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MHDTARIFLELGAVLFALGVLGHFALRVGISPIPLYLIGGLAFGHGGVLPLGASEDFIEI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCCCHHHHHH
GAEIGVILLLLTLGLEYTAEELLHGLRRQAPAGVLDLTLNAVPGVAAAFLLGWGPLAAVV
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEHHHHHCHHHHHHHHHHHHHHHHHH
MGGVTAISSSGIIAKVLGDLGRIGNRETPVVLSVLVLEDLAMAVYLPVVTALLAHHTFAR
HCCHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSLTVAVALGALVAVLYVALRHSDKVTLLVFSPNVDRNDEVLLLRSLGLTLLVAGVAQRM
CHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHH
QVSAAVGAFLVGIALSGPVAEGAHEVLMPLRDLFAAVFFVFFGLQTDPVEIPPVLLAASL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LALAGVATKIVTGWWAARRAGIATMGRYRAGAALVARGEFSIVIAGLAVAAGVNPQLGPL
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCCHHH
AACYVLLMAVLGPLAARFVEPVVRTIRRWSRARRPPDPATARGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]