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The map label for this gene is ctaB

Identifier: 158313910

GI number: 158313910

Start: 2500593

End: 2501534

Strand: Direct

Name: ctaB

Synonym: Franean1_2075

Alternate gene names: 158313910

Gene position: 2500593-2501534 (Clockwise)

Preceding gene: 158313905

Following gene: 158313911

Centisome position: 27.84

GC content: 70.91

Gene sequence:

>942_bases
GTGGCGGCGCCGGCCGCCGGGGCGGAGCCGTCCAGTGACCCCCTCGTCGTTCCCCGCGGCCGACTGGCCCGGGCGACCGA
CCGGGCCCGGTCCTACATAGCGTTGATGAAGCTGCGGGTCGTGGAGCTGCTCCTCGTCTCCACGGTGCCGGTCATGCTCC
TCGCCGAACGCGGGATGCCGTCCTGGTGGCTGATCGCGGTGACGCTGCTCGCCGGCACCCTCTCCGCCGGCAGCGCCAAC
ACGATCAACTGCTACGTCGACCGCGACATCGACCAGCTCATGGGCCGCACGAAACGCCGCCCGCTCGTCCGGGAGGTCGT
CGAGCCCGCCCAGGCGCTGCGTTTCGGCATCGCCCTCGGCATCATCTCGACCCTCATGTTCGGCCTGCTGGTCAACTGGA
CATCGGCCGTGCTGTCCGTCGGGGCCATCGCCTTCTACGTCTTCGTCTACACGCTCGGCCTCAAGCGACGCTCCCCGTCG
AACATCGTCATCGGCGGTGCCGCCGGCTGCTTCCCGGTGCTGATCGGCTGGTCCGCCGTGACCGGCACGGTCGGCTGGCC
CGCCGTGCTGCTCTTCGCGGTCGTGTTCTTCTGGACGCCGCCGCACTTCTGGGCGCTGGCGATCCGCTTCAAGGACGACT
ACGCCGCCGCCGGCGTCCCGATGCTCCCCGTGGTGGCGACGCTCGAGGTCGTCACCCGCCGCATCCTGGCCTACTCCTAC
CTGATGGTCGCGGTCTCCCTCGCCGTCGCCCCCGTGGCCGACATCGGCCTGGTGTACCTGGTCCCGGCGGTCCTGCTCGG
CGCCTGGTTCGTCGCCGAGGCCCACCGGATGGCCGCCCGCGCCAAGCGCGGCGAGGAGATCAAGCCGATGCGCCTGTTCC
ACATGTCCATCACCTACCTGACCCTCCTCTTCGCGGCCCTGGCCGCCGCGGCGCTGCTCTGA

Upstream 100 bases:

>100_bases
CGGTGGGCTCCCCGTAGGCGGGCTTCCCGTCGGTGGGCTCCCTGTCAGCGGGCTTCCCGTCCGCGGCGCGGTGTCCGATC
CCGGCGGGGTGTCCGCCGCG

Downstream 100 bases:

>100_bases
CACCCCCCTGATCCGGCACCGCTGTTAGCTGACTCCCGCCCGTCACCCGCATCCAGGGTGACGGGCGTCGTCGGTTTGAG
GGGCCTGACTGGTGGACGTC

Product: protoheme IX farnesyltransferase

Products: NA

Alternate protein names: Heme B farnesyltransferase; Heme O synthase

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MAAPAAGAEPSSDPLVVPRGRLARATDRARSYIALMKLRVVELLLVSTVPVMLLAERGMPSWWLIAVTLLAGTLSAGSAN
TINCYVDRDIDQLMGRTKRRPLVREVVEPAQALRFGIALGIISTLMFGLLVNWTSAVLSVGAIAFYVFVYTLGLKRRSPS
NIVIGGAAGCFPVLIGWSAVTGTVGWPAVLLFAVVFFWTPPHFWALAIRFKDDYAAAGVPMLPVVATLEVVTRRILAYSY
LMVAVSLAVAPVADIGLVYLVPAVLLGAWFVAEAHRMAARAKRGEEIKPMRLFHMSITYLTLLFAALAAAALL

Sequences:

>Translated_313_residues
MAAPAAGAEPSSDPLVVPRGRLARATDRARSYIALMKLRVVELLLVSTVPVMLLAERGMPSWWLIAVTLLAGTLSAGSAN
TINCYVDRDIDQLMGRTKRRPLVREVVEPAQALRFGIALGIISTLMFGLLVNWTSAVLSVGAIAFYVFVYTLGLKRRSPS
NIVIGGAAGCFPVLIGWSAVTGTVGWPAVLLFAVVFFWTPPHFWALAIRFKDDYAAAGVPMLPVVATLEVVTRRILAYSY
LMVAVSLAVAPVADIGLVYLVPAVLLGAWFVAEAHRMAARAKRGEEIKPMRLFHMSITYLTLLFAALAAAALL
>Mature_312_residues
AAPAAGAEPSSDPLVVPRGRLARATDRARSYIALMKLRVVELLLVSTVPVMLLAERGMPSWWLIAVTLLAGTLSAGSANT
INCYVDRDIDQLMGRTKRRPLVREVVEPAQALRFGIALGIISTLMFGLLVNWTSAVLSVGAIAFYVFVYTLGLKRRSPSN
IVIGGAAGCFPVLIGWSAVTGTVGWPAVLLFAVVFFWTPPHFWALAIRFKDDYAAAGVPMLPVVATLEVVTRRILAYSYL
MVAVSLAVAPVADIGLVYLVPAVLLGAWFVAEAHRMAARAKRGEEIKPMRLFHMSITYLTLLFAALAAAALL

Specific function: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group

COG id: COG0109

COG function: function code O; Polyprenyltransferase (cytochrome oxidase assembly factor)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily

Homologues:

Organism=Homo sapiens, GI17921982, Length=255, Percent_Identity=31.3725490196078, Blast_Score=96, Evalue=4e-20,
Organism=Escherichia coli, GI1786631, Length=275, Percent_Identity=34.5454545454545, Blast_Score=129, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71998235, Length=265, Percent_Identity=27.1698113207547, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6325085, Length=242, Percent_Identity=31.8181818181818, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19921064, Length=277, Percent_Identity=32.4909747292419, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COXX_FRASN (A8KYS6)

Other databases:

- EMBL:   CP000820
- RefSeq:   YP_001506418.1
- GeneID:   5670476
- GenomeReviews:   CP000820_GR
- KEGG:   fre:Franean1_2075
- HOGENOM:   HBG656003
- OMA:   MALTEEW
- ProtClustDB:   PRK04375
- BioCyc:   FSP1855:FRANEAN1_2075-MONOMER
- HAMAP:   MF_00154
- InterPro:   IPR006369
- InterPro:   IPR000537
- PANTHER:   PTHR11048:SF3
- TIGRFAMs:   TIGR01473

Pfam domain/function: PF01040 UbiA

EC number: 2.5.1.-

Molecular weight: Translated: 33736; Mature: 33605

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x16ed6588)-; HASH(0x1aa81be4)-; HASH(0x1a423068)-; HASH(0x1ab7c458)-; HASH(0x1a66b974)-; HASH(0x1ab7199c)-; HASH(0x19c54784)-; HASH(0x1ab56c2c)-; HASH(0x1a42302c)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPAAGAEPSSDPLVVPRGRLARATDRARSYIALMKLRVVELLLVSTVPVMLLAERGMP
CCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SWWLIAVTLLAGTLSAGSANTINCYVDRDIDQLMGRTKRRPLVREVVEPAQALRFGIALG
HHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHCHHCCCHHHHHHHHHHHHHHHHHHHH
IISTLMFGLLVNWTSAVLSVGAIAFYVFVYTLGLKRRSPSNIVIGGAAGCFPVLIGWSAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHH
TGTVGWPAVLLFAVVFFWTPPHFWALAIRFKDDYAAAGVPMLPVVATLEVVTRRILAYSY
HCCCCHHHHHHHHHHHHHCCCHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LMVAVSLAVAPVADIGLVYLVPAVLLGAWFVAEAHRMAARAKRGEEIKPMRLFHMSITYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
TLLFAALAAAALL
HHHHHHHHHHHCH
>Mature Secondary Structure 
AAPAAGAEPSSDPLVVPRGRLARATDRARSYIALMKLRVVELLLVSTVPVMLLAERGMP
CCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SWWLIAVTLLAGTLSAGSANTINCYVDRDIDQLMGRTKRRPLVREVVEPAQALRFGIALG
HHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHCHHCCCHHHHHHHHHHHHHHHHHHHH
IISTLMFGLLVNWTSAVLSVGAIAFYVFVYTLGLKRRSPSNIVIGGAAGCFPVLIGWSAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHH
TGTVGWPAVLLFAVVFFWTPPHFWALAIRFKDDYAAAGVPMLPVVATLEVVTRRILAYSY
HCCCCHHHHHHHHHHHHHCCCHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LMVAVSLAVAPVADIGLVYLVPAVLLGAWFVAEAHRMAARAKRGEEIKPMRLFHMSITYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
TLLFAALAAAALL
HHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA