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The map label for this gene is gap [H]

Identifier: 158313898

GI number: 158313898

Start: 2486671

End: 2487678

Strand: Direct

Name: gap [H]

Synonym: Franean1_2063

Alternate gene names: 158313898

Gene position: 2486671-2487678 (Clockwise)

Preceding gene: 158313897

Following gene: 158313899

Centisome position: 27.68

GC content: 65.87

Gene sequence:

>1008_bases
GTGGCTACGCGGGTGGGTGTCAACGGCTTCGGGCGAATCGGTCGTAACTTCTGGCGGGCGCTTGCAGCCAGCCGGCGTAG
TGATCTGGAGATCGTCGCCGTCAACGACCTGACGGACAACAAGACGCTCGCGCACCTGCTGAAGTACGACACGACTCTGG
GCACGCTGCCCGAGTCGGTCTCCGTCGGCGAGGACGGCATCCGCGTCGGCGACAGCACGATCAAGGTGCTTGCGGAGCGT
GACCCGGCCGCCCTGCCCTGGGCTGACCTGGGCGTCGACGTGGTGATCGAGTCGACCGGCCGCTTCACCACGGCCGAGAC
GGCCGGCAAGCACCTGACCGCCGGGGCGAAGAAGGTCATCATCTCGGCGCCGGCCAAGGGTGAGGACCTCACGGTCGTCA
TGGGCGTGAACGACGACGTCTACGACCCGGCGAAGCACCATATCCTCTCGAACGCTTCCTGCACGACGAACTGTGTCGCG
CCATTGGCGAAGGTTCTCGACGAGGCGTTCGGTATCGAGCGTGGTCTGATGACCACGATCCACGCTTACACCAATGACCA
GGTCATCCTTGACTTCCCGCATTCCGACCTGCGTCGGGCGCGGGCGGCGGCGCAGAACATCATTCCCACCACCACCGGTG
CTGCGAAGGCGACCGCTCTCGTGCTCCCGCACCTCAAGGGCAAGCTCGACGGCATCGCGATGCGTGTTCCGGTCCTTGAC
GGCTCGGTCACCGACCTTGTCGTGAACCTGGCCCGTCCCGCGTCGAAGGACGAGATCAACGCCGCGTACAAGGCGGCGGC
GGAAGGCCCGCTGAAGGGCTATCTCGTCTACACGGAGGACCCGATCGTGTCCTCCGACATCGTGGGCACCCCGGCGTCGT
GCACCTTCGACTCGCTGCTCACGATGTCCAGCGGCAGCCAGGTGAAGGTCGTCGGCTGGTACGACAACGAGTGGGGTTAC
TCCAACCGGCTCGTCGACCTGACCGGGCTCGTCGCCGCCCGGATCTGA

Upstream 100 bases:

>100_bases
GAGGAGACCGACATGGATCAGTTCGGATTCCCGCCGATGATGTCCCGACTCGCTAGGCTCCTGGCACACGACGGCACACG
AGCATAGGGGAGTCCTGGAC

Downstream 100 bases:

>100_bases
CATCGGCGAACCGGCCCGTCCATCGCACCTTCGCCCACCCCGGAGCAGCCCAGCGTGAGGACGATCGACGACCTGCAGGT
CACCGGTCACCGCGTACTTG

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MATRVGVNGFGRIGRNFWRALAASRRSDLEIVAVNDLTDNKTLAHLLKYDTTLGTLPESVSVGEDGIRVGDSTIKVLAER
DPAALPWADLGVDVVIESTGRFTTAETAGKHLTAGAKKVIISAPAKGEDLTVVMGVNDDVYDPAKHHILSNASCTTNCVA
PLAKVLDEAFGIERGLMTTIHAYTNDQVILDFPHSDLRRARAAAQNIIPTTTGAAKATALVLPHLKGKLDGIAMRVPVLD
GSVTDLVVNLARPASKDEINAAYKAAAEGPLKGYLVYTEDPIVSSDIVGTPASCTFDSLLTMSSGSQVKVVGWYDNEWGY
SNRLVDLTGLVAARI

Sequences:

>Translated_335_residues
MATRVGVNGFGRIGRNFWRALAASRRSDLEIVAVNDLTDNKTLAHLLKYDTTLGTLPESVSVGEDGIRVGDSTIKVLAER
DPAALPWADLGVDVVIESTGRFTTAETAGKHLTAGAKKVIISAPAKGEDLTVVMGVNDDVYDPAKHHILSNASCTTNCVA
PLAKVLDEAFGIERGLMTTIHAYTNDQVILDFPHSDLRRARAAAQNIIPTTTGAAKATALVLPHLKGKLDGIAMRVPVLD
GSVTDLVVNLARPASKDEINAAYKAAAEGPLKGYLVYTEDPIVSSDIVGTPASCTFDSLLTMSSGSQVKVVGWYDNEWGY
SNRLVDLTGLVAARI
>Mature_334_residues
ATRVGVNGFGRIGRNFWRALAASRRSDLEIVAVNDLTDNKTLAHLLKYDTTLGTLPESVSVGEDGIRVGDSTIKVLAERD
PAALPWADLGVDVVIESTGRFTTAETAGKHLTAGAKKVIISAPAKGEDLTVVMGVNDDVYDPAKHHILSNASCTTNCVAP
LAKVLDEAFGIERGLMTTIHAYTNDQVILDFPHSDLRRARAAAQNIIPTTTGAAKATALVLPHLKGKLDGIAMRVPVLDG
SVTDLVVNLARPASKDEINAAYKAAAEGPLKGYLVYTEDPIVSSDIVGTPASCTFDSLLTMSSGSQVKVVGWYDNEWGYS
NRLVDLTGLVAARI

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=334, Percent_Identity=49.1017964071856, Blast_Score=296, Evalue=2e-80,
Organism=Homo sapiens, GI7657116, Length=333, Percent_Identity=46.8468468468468, Blast_Score=290, Evalue=1e-78,
Organism=Escherichia coli, GI1788079, Length=329, Percent_Identity=53.4954407294833, Blast_Score=327, Evalue=7e-91,
Organism=Escherichia coli, GI1789295, Length=331, Percent_Identity=46.2235649546828, Blast_Score=296, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI17534679, Length=339, Percent_Identity=51.9174041297935, Blast_Score=316, Evalue=9e-87,
Organism=Caenorhabditis elegans, GI17534677, Length=339, Percent_Identity=51.9174041297935, Blast_Score=316, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI32566163, Length=338, Percent_Identity=50.887573964497, Blast_Score=304, Evalue=4e-83,
Organism=Caenorhabditis elegans, GI17568413, Length=338, Percent_Identity=50.887573964497, Blast_Score=303, Evalue=6e-83,
Organism=Saccharomyces cerevisiae, GI6322409, Length=336, Percent_Identity=52.0833333333333, Blast_Score=315, Evalue=6e-87,
Organism=Saccharomyces cerevisiae, GI6322468, Length=332, Percent_Identity=52.1084337349398, Blast_Score=311, Evalue=1e-85,
Organism=Saccharomyces cerevisiae, GI6321631, Length=336, Percent_Identity=51.7857142857143, Blast_Score=305, Evalue=8e-84,
Organism=Drosophila melanogaster, GI19922412, Length=326, Percent_Identity=48.159509202454, Blast_Score=285, Evalue=2e-77,
Organism=Drosophila melanogaster, GI17933600, Length=335, Percent_Identity=47.4626865671642, Blast_Score=284, Evalue=7e-77,
Organism=Drosophila melanogaster, GI18110149, Length=335, Percent_Identity=47.4626865671642, Blast_Score=284, Evalue=7e-77,
Organism=Drosophila melanogaster, GI85725000, Length=335, Percent_Identity=47.4626865671642, Blast_Score=281, Evalue=4e-76,
Organism=Drosophila melanogaster, GI22023983, Length=335, Percent_Identity=47.4626865671642, Blast_Score=281, Evalue=4e-76,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35551; Mature: 35420

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRVGVNGFGRIGRNFWRALAASRRSDLEIVAVNDLTDNKTLAHLLKYDTTLGTLPESV
CCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCHHCCCCCCC
SVGEDGIRVGDSTIKVLAERDPAALPWADLGVDVVIESTGRFTTAETAGKHLTAGAKKVI
CCCCCCEEECCHHEEEEECCCCCCCCHHHCCEEEEEECCCCEEEHHHCCCEECCCCEEEE
ISAPAKGEDLTVVMGVNDDVYDPAKHHILSNASCTTNCVAPLAKVLDEAFGIERGLMTTI
EECCCCCCCEEEEEECCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEE
HAYTNDQVILDFPHSDLRRARAAAQNIIPTTTGAAKATALVLPHLKGKLDGIAMRVPVLD
EEECCCEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHEEEEECCCCCCCCCEEEEEEECC
GSVTDLVVNLARPASKDEINAAYKAAAEGPLKGYLVYTEDPIVSSDIVGTPASCTFDSLL
CCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHH
TMSSGSQVKVVGWYDNEWGYSNRLVDLTGLVAARI
EECCCCEEEEEEEECCCCCCCCCEEEHHHHHHHCC
>Mature Secondary Structure 
ATRVGVNGFGRIGRNFWRALAASRRSDLEIVAVNDLTDNKTLAHLLKYDTTLGTLPESV
CCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCHHCCCCCCC
SVGEDGIRVGDSTIKVLAERDPAALPWADLGVDVVIESTGRFTTAETAGKHLTAGAKKVI
CCCCCCEEECCHHEEEEECCCCCCCCHHHCCEEEEEECCCCEEEHHHCCCEECCCCEEEE
ISAPAKGEDLTVVMGVNDDVYDPAKHHILSNASCTTNCVAPLAKVLDEAFGIERGLMTTI
EECCCCCCCEEEEEECCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEE
HAYTNDQVILDFPHSDLRRARAAAQNIIPTTTGAAKATALVLPHLKGKLDGIAMRVPVLD
EEECCCEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHEEEEECCCCCCCCCEEEEEEECC
GSVTDLVVNLARPASKDEINAAYKAAAEGPLKGYLVYTEDPIVSSDIVGTPASCTFDSLL
CCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHH
TMSSGSQVKVVGWYDNEWGYSNRLVDLTGLVAARI
EECCCCEEEEEEEECCCCCCCCCEEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]