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The map label for this gene is caiD [C]

Identifier: 158313843

GI number: 158313843

Start: 2414054

End: 2414884

Strand: Direct

Name: caiD [C]

Synonym: Franean1_2008

Alternate gene names: 158313843

Gene position: 2414054-2414884 (Clockwise)

Preceding gene: 158313842

Following gene: 158313847

Centisome position: 26.88

GC content: 63.66

Gene sequence:

>831_bases
GTGGGTAGCCACAGTTTCGAGATAGACGTGGTCGACAAGGTCGCGTGGCTCGTTCTCTCCAGGCCGGAAGAACTCAACAC
GCTTCAACCAGATTTCTGGCGAGATCTCCCCCTGGCCGTTTCGAAGATTGACCAGGGCGGAGGCGTCCGGGTGCTCGTGA
TCTCGTCGACCGGTCGACACTTCACCGCGGGCCTGGACCTTAATGTCTTCGGCGGCACGGAGCTTTTTCCGGACGGAGAG
CCGGCTCGTGTCAACATGGCCCGCCGCTCGCTTATTCTTCGCATGCAGGGCGCTCTCACTGCGCTGGAACGGGTGCGCTT
CCCCGTTCTCGCGGCGGTGCAGGGCGGTTGTGTCGGGGGCGGCCTCGACCTTGTGACGGCCTGCGACATGCGTTATGCCA
CCGTGGACGCGTTTTTCGTTGTTCAGGAGACAAAGATCGGAATTACCGCCGATCTCGGCACACTGCAGCGACTCCCCAAG
ATAATTCCGGACGGAGTTGCGCGTGAGCTCGTCTACACCGGTCGTCGACTTCCCGCCGACCGTGCGCTCGCCGTCGGCCT
GGTGAACGAGGTCTACCCGGATCAGGAAGCGATGCTGCGCGGCGTGCGCGAGGTTGCGGAGGAAATTGCCGCCAACAGCC
CAATGGCGGTCTGGGGGAGCAAGGAGATGCTGCTCTACTCGCGCGATCACCCCGTCGCCGACGCCCTGGCACACACGGCA
ACCTGGCAGGCGGGGGCACTCCAGCCAGTAGACGTTACCGAGTCGATTCAGGCCCGGATGGAGAAGCGCGTCCCGAGCTA
CCCGGATCTCCCGTCGACCTCGGATACCTGA

Upstream 100 bases:

>100_bases
GCCAGGGCGCTCGGCACCGTAGGCGTGATCTTGCGGCGAGTGTGTCGATGGGAGAAGGTGGACAGATTCGGCCGGGACAC
AGTTTCTTCGGGAGTCTTTC

Downstream 100 bases:

>100_bases
CGGCGCCGTCGTCCGAATCCGAGTGTCCTGTCGAAGCCCGTCCTGTACGAGACCGAATCCCTCCTCGTGGTTCGCCTCAG
GAGGGTGGGTTCAGGTGTCG

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MGSHSFEIDVVDKVAWLVLSRPEELNTLQPDFWRDLPLAVSKIDQGGGVRVLVISSTGRHFTAGLDLNVFGGTELFPDGE
PARVNMARRSLILRMQGALTALERVRFPVLAAVQGGCVGGGLDLVTACDMRYATVDAFFVVQETKIGITADLGTLQRLPK
IIPDGVARELVYTGRRLPADRALAVGLVNEVYPDQEAMLRGVREVAEEIAANSPMAVWGSKEMLLYSRDHPVADALAHTA
TWQAGALQPVDVTESIQARMEKRVPSYPDLPSTSDT

Sequences:

>Translated_276_residues
MGSHSFEIDVVDKVAWLVLSRPEELNTLQPDFWRDLPLAVSKIDQGGGVRVLVISSTGRHFTAGLDLNVFGGTELFPDGE
PARVNMARRSLILRMQGALTALERVRFPVLAAVQGGCVGGGLDLVTACDMRYATVDAFFVVQETKIGITADLGTLQRLPK
IIPDGVARELVYTGRRLPADRALAVGLVNEVYPDQEAMLRGVREVAEEIAANSPMAVWGSKEMLLYSRDHPVADALAHTA
TWQAGALQPVDVTESIQARMEKRVPSYPDLPSTSDT
>Mature_275_residues
GSHSFEIDVVDKVAWLVLSRPEELNTLQPDFWRDLPLAVSKIDQGGGVRVLVISSTGRHFTAGLDLNVFGGTELFPDGEP
ARVNMARRSLILRMQGALTALERVRFPVLAAVQGGCVGGGLDLVTACDMRYATVDAFFVVQETKIGITADLGTLQRLPKI
IPDGVARELVYTGRRLPADRALAVGLVNEVYPDQEAMLRGVREVAEEIAANSPMAVWGSKEMLLYSRDHPVADALAHTAT
WQAGALQPVDVTESIQARMEKRVPSYPDLPSTSDT

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=266, Percent_Identity=43.984962406015, Blast_Score=225, Evalue=3e-59,
Organism=Homo sapiens, GI194097323, Length=271, Percent_Identity=28.4132841328413, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI20127408, Length=205, Percent_Identity=28.780487804878, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI221307494, Length=212, Percent_Identity=26.4150943396226, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI221136756, Length=212, Percent_Identity=26.4150943396226, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI221136753, Length=212, Percent_Identity=26.4150943396226, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI68989263, Length=228, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI260274832, Length=227, Percent_Identity=26.8722466960352, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI45643119, Length=197, Percent_Identity=27.4111675126904, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI260275230, Length=197, Percent_Identity=27.4111675126904, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI31542718, Length=261, Percent_Identity=25.6704980842912, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI116235487, Length=198, Percent_Identity=26.7676767676768, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4502327, Length=258, Percent_Identity=27.906976744186, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI221142681, Length=224, Percent_Identity=32.5892857142857, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1787659, Length=256, Percent_Identity=28.515625, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788682, Length=220, Percent_Identity=29.0909090909091, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790281, Length=194, Percent_Identity=30.4123711340206, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI87082183, Length=273, Percent_Identity=23.8095238095238, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787660, Length=264, Percent_Identity=26.1363636363636, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788597, Length=208, Percent_Identity=26.4423076923077, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17536985, Length=258, Percent_Identity=35.2713178294574, Blast_Score=183, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI17534483, Length=268, Percent_Identity=36.1940298507463, Blast_Score=167, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI25145438, Length=256, Percent_Identity=29.296875, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17554946, Length=258, Percent_Identity=27.906976744186, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17540714, Length=215, Percent_Identity=28.8372093023256, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17558304, Length=169, Percent_Identity=27.2189349112426, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560910, Length=239, Percent_Identity=24.6861924686192, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17540306, Length=254, Percent_Identity=26.7716535433071, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920382, Length=247, Percent_Identity=38.4615384615385, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24653139, Length=258, Percent_Identity=29.4573643410853, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI20129971, Length=258, Percent_Identity=24.4186046511628, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24653477, Length=258, Percent_Identity=24.4186046511628, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24650670, Length=263, Percent_Identity=25.8555133079848, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24583165, Length=212, Percent_Identity=26.4150943396226, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45550169, Length=219, Percent_Identity=25.5707762557078, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19921018, Length=211, Percent_Identity=25.5924170616114, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 29979; Mature: 29848

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00659 GLYCOSYL_HYDROL_F5 ; PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSHSFEIDVVDKVAWLVLSRPEELNTLQPDFWRDLPLAVSKIDQGGGVRVLVISSTGRH
CCCCEEEEEHHHHHHHHHHCCCHHCCCCCCHHHHCCCHHHHHHCCCCCEEEEEEECCCCE
FTAGLDLNVFGGTELFPDGEPARVNMARRSLILRMQGALTALERVRFPVLAAVQGGCVGG
EEECEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCC
GLDLVTACDMRYATVDAFFVVQETKIGITADLGTLQRLPKIIPDGVARELVYTGRRLPAD
CHHHHHHCCCHHEEEEEEEEEEECCCCEEECHHHHHHHHHHCCCHHHHHHHHHCCCCCHH
RALAVGLVNEVYPDQEAMLRGVREVAEEIAANSPMAVWGSKEMLLYSRDHPVADALAHTA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCHHHHHHHHC
TWQAGALQPVDVTESIQARMEKRVPSYPDLPSTSDT
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
GSHSFEIDVVDKVAWLVLSRPEELNTLQPDFWRDLPLAVSKIDQGGGVRVLVISSTGRH
CCCEEEEEHHHHHHHHHHCCCHHCCCCCCHHHHCCCHHHHHHCCCCCEEEEEEECCCCE
FTAGLDLNVFGGTELFPDGEPARVNMARRSLILRMQGALTALERVRFPVLAAVQGGCVGG
EEECEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCC
GLDLVTACDMRYATVDAFFVVQETKIGITADLGTLQRLPKIIPDGVARELVYTGRRLPAD
CHHHHHHCCCHHEEEEEEEEEEECCCCEEECHHHHHHHHHHCCCHHHHHHHHHCCCCCHH
RALAVGLVNEVYPDQEAMLRGVREVAEEIAANSPMAVWGSKEMLLYSRDHPVADALAHTA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCHHHHHHHHC
TWQAGALQPVDVTESIQARMEKRVPSYPDLPSTSDT
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA