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The map label for this gene is trpB [H]

Identifier: 158313767

GI number: 158313767

Start: 2314669

End: 2316141

Strand: Direct

Name: trpB [H]

Synonym: Franean1_1932

Alternate gene names: 158313767

Gene position: 2314669-2316141 (Clockwise)

Preceding gene: 158313766

Following gene: 158313768

Centisome position: 25.77

GC content: 72.84

Gene sequence:

>1473_bases
GTGCTCTGTGTTCGGAGCGTCTCCGGGCGGGGCCCGGCCCCGCACGTCACCTCGGTGGGGGTGGGCGCCGGTACAGTCGA
GGCCGTGACAGCTCGATCCGTCGACACCACCGCCGACCCGACCTCCGCCATCGATCCGAGCCGTGCCACCGACCCGAGCC
GCGCGACCGGCCCGGTCGAGGTCGGCACGTGGTCGGCCGCCCAGGCGGCGGGGAACTGGCAGGCCGTACCGGATGCCGCC
GGTCACTACGGCCGTTTCGGCGGGCGGTTCGTCCCGGAGGCGCTGTTCGCGGCGCTCGACGAGCTCACCGCGGCCTACGA
GGCCGCCCGGGTCGACCCCGCCTTCGTCGATGAGCTCGACCGCCTGTTGGCGAGCTACGCCGGGCGCCCGACGCCGCTGA
CCTCGGCCGACCGGCTCACGGAGCGGATCGGTGGCGCGCGCATCCTGCTCAAGCGCGAGGATCTCGCGCACACCGGCTCA
CACAAGATCAACAATGTTCTCGGGCAGTGCCTCCTCACCCGGCGGATGGGCAAGACCCGGGTGATCGCCGAGACCGGAGC
CGGTCAGCACGGCGTGGCCACCGCCACCGCCTGCGCCCTGCTGGGGCTGGAGTGCGTCGTCTACATGGGCGAGGAGGACA
CTCGCCGGCAGGCGCTCAACGTCGCCCGGATGCGCCTGCTCGGTGCCGAGGTGGTCCCCGTCGCGTCGGGCAGCCGCACC
CTGAAGGACGCCATCAACGAGGCCATGCGCGACTGGGTGGCCACCGTCGACTCGACCCACTACTGCATCGGGTCCGTGAT
GGGCCCGCACCCGTTCCCGATGATGGTCCGTGACTTCCAGCGGATCATCGGCGTGGAGGCGCGTCAGCAGACGCTCGACC
TGCTCGGCCGCCTGCCCGACGCCGTCGTCGCCTGTGTCGGGGGCGGGTCGAACGCGATGGGCGTCTTCCACCGCTTCATC
CCGGACACCGAGGTCGCCCTGATTGGCTGCGAGGCCGGCGGCGACGGAGTGGTGACGGGCCGCCACGCCGCGGCGATCGC
CGGGGGCGCGCCCGGGGTCCTGCACGGCATGCGGACCTTCCTCCTCCAGGACGCGGACGGCCAGACCCAGGTCTCCCATT
CCATCTCGGCCGGGCTCGACTACCCGGGCATCGGCCCTGAGCACGCCCTCCTGCACGAGACCGGCCGGGCCAGCTACCGG
GTGGTCGACGACAGTGCCGCGATGGAGGCACTGGCACTGGTCGCGCGGACGGAGGGCATCCTCGTCGCGATCGAGAGCGC
ACACGCCTTCGCCGGCGCGTTCGAGGTGGCCCGTGAGCTCGGCCCGGACGCCGTCGTCCTGGTCAACTGCTCCGGCCGGG
GGGACAAGGACGTCGACACGGCCGCCCGCTGGTTCGATCTGCTGGACACGGACGACACGGACGCCGAGTCTCGGGGCGAG
GGCGCAGCCCCGGCCACCGAACCGTCCGCCTGA

Upstream 100 bases:

>100_bases
CTGGAACGCATCCCGCCACCCGTATCGCGCACTGACCCGCCGACCGCTCGGGCGCTGCGGCAGGCGGTCGGCCGAGCGGT
CGCCGGCCGGCCCCGCACGG

Downstream 100 bases:

>100_bases
CGACAACGACGAGGAACGGACGCACGGTGCGGAGTCAAGTGGCGCACGACCAGTCGGCCCAGCAGGCATGGGCCCAGGAG
CAGCCGGCGCGCGACCAGCC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MLCVRSVSGRGPAPHVTSVGVGAGTVEAVTARSVDTTADPTSAIDPSRATDPSRATGPVEVGTWSAAQAAGNWQAVPDAA
GHYGRFGGRFVPEALFAALDELTAAYEAARVDPAFVDELDRLLASYAGRPTPLTSADRLTERIGGARILLKREDLAHTGS
HKINNVLGQCLLTRRMGKTRVIAETGAGQHGVATATACALLGLECVVYMGEEDTRRQALNVARMRLLGAEVVPVASGSRT
LKDAINEAMRDWVATVDSTHYCIGSVMGPHPFPMMVRDFQRIIGVEARQQTLDLLGRLPDAVVACVGGGSNAMGVFHRFI
PDTEVALIGCEAGGDGVVTGRHAAAIAGGAPGVLHGMRTFLLQDADGQTQVSHSISAGLDYPGIGPEHALLHETGRASYR
VVDDSAAMEALALVARTEGILVAIESAHAFAGAFEVARELGPDAVVLVNCSGRGDKDVDTAARWFDLLDTDDTDAESRGE
GAAPATEPSA

Sequences:

>Translated_490_residues
MLCVRSVSGRGPAPHVTSVGVGAGTVEAVTARSVDTTADPTSAIDPSRATDPSRATGPVEVGTWSAAQAAGNWQAVPDAA
GHYGRFGGRFVPEALFAALDELTAAYEAARVDPAFVDELDRLLASYAGRPTPLTSADRLTERIGGARILLKREDLAHTGS
HKINNVLGQCLLTRRMGKTRVIAETGAGQHGVATATACALLGLECVVYMGEEDTRRQALNVARMRLLGAEVVPVASGSRT
LKDAINEAMRDWVATVDSTHYCIGSVMGPHPFPMMVRDFQRIIGVEARQQTLDLLGRLPDAVVACVGGGSNAMGVFHRFI
PDTEVALIGCEAGGDGVVTGRHAAAIAGGAPGVLHGMRTFLLQDADGQTQVSHSISAGLDYPGIGPEHALLHETGRASYR
VVDDSAAMEALALVARTEGILVAIESAHAFAGAFEVARELGPDAVVLVNCSGRGDKDVDTAARWFDLLDTDDTDAESRGE
GAAPATEPSA
>Mature_490_residues
MLCVRSVSGRGPAPHVTSVGVGAGTVEAVTARSVDTTADPTSAIDPSRATDPSRATGPVEVGTWSAAQAAGNWQAVPDAA
GHYGRFGGRFVPEALFAALDELTAAYEAARVDPAFVDELDRLLASYAGRPTPLTSADRLTERIGGARILLKREDLAHTGS
HKINNVLGQCLLTRRMGKTRVIAETGAGQHGVATATACALLGLECVVYMGEEDTRRQALNVARMRLLGAEVVPVASGSRT
LKDAINEAMRDWVATVDSTHYCIGSVMGPHPFPMMVRDFQRIIGVEARQQTLDLLGRLPDAVVACVGGGSNAMGVFHRFI
PDTEVALIGCEAGGDGVVTGRHAAAIAGGAPGVLHGMRTFLLQDADGQTQVSHSISAGLDYPGIGPEHALLHETGRASYR
VVDDSAAMEALALVARTEGILVAIESAHAFAGAFEVARELGPDAVVLVNCSGRGDKDVDTAARWFDLLDTDDTDAESRGE
GAAPATEPSA

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=381, Percent_Identity=54.0682414698163, Blast_Score=419, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6321412, Length=382, Percent_Identity=56.020942408377, Blast_Score=444, Evalue=1e-125,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 51044; Mature: 51044

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLCVRSVSGRGPAPHVTSVGVGAGTVEAVTARSVDTTADPTSAIDPSRATDPSRATGPVE
CEEEECCCCCCCCCCCEECCCCCCCHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCEE
VGTWSAAQAAGNWQAVPDAAGHYGRFGGRFVPEALFAALDELTAAYEAARVDPAFVDELD
ECCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RLLASYAGRPTPLTSADRLTERIGGARILLKREDLAHTGSHKINNVLGQCLLTRRMGKTR
HHHHHHCCCCCCCCHHHHHHHHCCCEEEEEECHHHHHCCCHHHHHHHHHHHHHHHCCCEE
VIAETGAGQHGVATATACALLGLECVVYMGEEDTRRQALNVARMRLLGAEVVPVASGSRT
EEEECCCCCCCHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHCCCEEEECCCCHH
LKDAINEAMRDWVATVDSTHYCIGSVMGPHPFPMMVRDFQRIIGVEARQQTLDLLGRLPD
HHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCH
AVVACVGGGSNAMGVFHRFIPDTEVALIGCEAGGDGVVTGRHAAAIAGGAPGVLHGMRTF
HHEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCCCEEECCCHHEECCCCCHHHHHHHHH
LLQDADGQTQVSHSISAGLDYPGIGPEHALLHETGRASYRVVDDSAAMEALALVARTEGI
HHCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCE
LVAIESAHAFAGAFEVARELGPDAVVLVNCSGRGDKDVDTAARWFDLLDTDDTDAESRGE
EEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
GAAPATEPSA
CCCCCCCCCC
>Mature Secondary Structure
MLCVRSVSGRGPAPHVTSVGVGAGTVEAVTARSVDTTADPTSAIDPSRATDPSRATGPVE
CEEEECCCCCCCCCCCEECCCCCCCHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCEE
VGTWSAAQAAGNWQAVPDAAGHYGRFGGRFVPEALFAALDELTAAYEAARVDPAFVDELD
ECCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RLLASYAGRPTPLTSADRLTERIGGARILLKREDLAHTGSHKINNVLGQCLLTRRMGKTR
HHHHHHCCCCCCCCHHHHHHHHCCCEEEEEECHHHHHCCCHHHHHHHHHHHHHHHCCCEE
VIAETGAGQHGVATATACALLGLECVVYMGEEDTRRQALNVARMRLLGAEVVPVASGSRT
EEEECCCCCCCHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHCCCEEEECCCCHH
LKDAINEAMRDWVATVDSTHYCIGSVMGPHPFPMMVRDFQRIIGVEARQQTLDLLGRLPD
HHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCH
AVVACVGGGSNAMGVFHRFIPDTEVALIGCEAGGDGVVTGRHAAAIAGGAPGVLHGMRTF
HHEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCCCEEECCCHHEECCCCCHHHHHHHHH
LLQDADGQTQVSHSISAGLDYPGIGPEHALLHETGRASYRVVDDSAAMEALALVARTEGI
HHCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCE
LVAIESAHAFAGAFEVARELGPDAVVLVNCSGRGDKDVDTAARWFDLLDTDDTDAESRGE
EEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
GAAPATEPSA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]