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The map label for this gene is trpE [H]

Identifier: 158313763

GI number: 158313763

Start: 2310397

End: 2311974

Strand: Direct

Name: trpE [H]

Synonym: Franean1_1928

Alternate gene names: 158313763

Gene position: 2310397-2311974 (Clockwise)

Preceding gene: 158313762

Following gene: 158313764

Centisome position: 25.72

GC content: 71.55

Gene sequence:

>1578_bases
ATGACCACCGGCGAGATCACACCGAGCCGGGCGGAGTTCCACGAGCTCGCCGCGCGCCAGCCGGTCGTCGCGGTGTCCCG
CCGCCTGCTCGCCGACGGCGAGACACCGGTCGGGGTCTACCGCAAGCTGGCCGGCGGGCCGGGGACGTTTCTGCTCGAGT
CTGCCGAGCACGGGGGCGTGTGGTCGCGTTACTCCTTCGTCGGCGTCCGTGCCGCGGCCACACTCACTGAACGGGACGGG
CAGGCCGCCTGGACGGACGGAACCCCGCCGCCCGGTGTCCCGCTCGACGGCGACCCGCTCGATGTCCTGCGTGCCGTGGA
ACGCCAGCTCTGCTCGGCCCGGCCGAGTGGCACTCCGCCGCTGCTGGGCGGCCTGGTCGGGTACCTCTCGTACGACATCG
TCCGGCGCATCGAGCGGTTGCCCGCCCGGGCAACCGACGATCTCGGGATGCCCGAGCTGCGGATGCTCCTGACGACCGAC
CTGGCCGTCCTCGACCACACCGACGGATCGTGCCAGCTCGTCGCGAACATCTTCACCGGCGCCGGGGACCCGGCCGACCC
GGCCGAAGCAGCGGACCTGGCTGGCCCAGGAGCGGCGGGCGGACCGTCCGCGCGGCGGGCGGAGCTGGACGCCGCCTACG
ACGATGCGGTGCACCGCATCGAGGTGATGACGGCAGATCTCGGCAAGTGGAGTGAGCCGACCGTGGCGACCACAACCGGG
GCGTCCACGGGCGTGCGCGACTTCGCCTCCGCAACCCCGCCCGGCGGCTTCCACGCTGCCGTCGAGCGGTCGATCGAGGA
GATCCGGGCGGGGGAGTGCTTCCAGATCGTGGTCTCCCAGCGGTTCGAGCGCCCCACCACCGCTGACGCCCTCGACGTCT
ACCGGGTCCTGCGGGCGTCGAACCCCAGCCCCTACATGTACCTGCTGCGGTTCGCCGATCATGATGTGGTCGGCTCGTCG
CCGGAGGCGCACGTCAAGGTCACCGGCCGCCGGGCGTTGCTGCACCCGATCGCGGGCAGCCGGCCGAGGGGCGAGACCCC
CGAGCGCGATGCCGAACTGGCTGCCCAGCTCCTGGCCGATCCGAAGGAACGGTCCGAGCACGTGATGCTGGTCGACCTGG
TCCGCAATGATCTCGGGCGGGTCTGCGTGCCCGGATCGGTGCGGGTGGTCGAGTTCGCGTCCGTCGAGCGGTTCTCGCAC
ATCATGCACATCGTCTCCACCGTGATCGGTGAGGTGGCGCCCGAGCGCAGCGCGGTCGACGTCCTCGCCGCGACCTTTCC
CGCCGGGACGTTGTCGGGAGCGCCCAAGGTGCGGGCCATGGAGATCATCGACGAGCTCGAGCCGACGAGGCGCGGCCTGT
ACGGCGGGGTCGTGGGATATCTCGATTTCGGCGGTGACCTCGACACCGCGATCGCCATCCGCACAGCGGTCCTCCGTTCA
GGAATGGCCTACGTGCAGGCCGGCGCCGGGATCGTGGCGGACTCCGTTCCCGACACCGAGGATCTCGAGAGCCGGACGAA
GGCCGCGGCGGTTCTCCGCGCGATCGAGGTGGCGGAGTCGCTCCGCCCGCCGGTATGA

Upstream 100 bases:

>100_bases
GGCCCCTGCAGCCCCCGGCCGTGAACCCCACGCCGACGCCGACCTCCACGCCCATGTCCATGCCGGCAGCGGCGCCGGCG
CCGACGACGGGAGCACCACG

Downstream 100 bases:

>100_bases
CAGCGCCCGCCGACCTGCCCGCGCCCGCAGGAAGCCCCGCTCCCGGCGCCCGCCGGGAGCGGGCGCTCGCCATGGTCGCG
TGCCTGGTCGGATCCGCCGT

Product: anthranilate synthase component I

Products: NA

Alternate protein names: Anthranilate synthase component I [H]

Number of amino acids: Translated: 525; Mature: 524

Protein sequence:

>525_residues
MTTGEITPSRAEFHELAARQPVVAVSRRLLADGETPVGVYRKLAGGPGTFLLESAEHGGVWSRYSFVGVRAAATLTERDG
QAAWTDGTPPPGVPLDGDPLDVLRAVERQLCSARPSGTPPLLGGLVGYLSYDIVRRIERLPARATDDLGMPELRMLLTTD
LAVLDHTDGSCQLVANIFTGAGDPADPAEAADLAGPGAAGGPSARRAELDAAYDDAVHRIEVMTADLGKWSEPTVATTTG
ASTGVRDFASATPPGGFHAAVERSIEEIRAGECFQIVVSQRFERPTTADALDVYRVLRASNPSPYMYLLRFADHDVVGSS
PEAHVKVTGRRALLHPIAGSRPRGETPERDAELAAQLLADPKERSEHVMLVDLVRNDLGRVCVPGSVRVVEFASVERFSH
IMHIVSTVIGEVAPERSAVDVLAATFPAGTLSGAPKVRAMEIIDELEPTRRGLYGGVVGYLDFGGDLDTAIAIRTAVLRS
GMAYVQAGAGIVADSVPDTEDLESRTKAAAVLRAIEVAESLRPPV

Sequences:

>Translated_525_residues
MTTGEITPSRAEFHELAARQPVVAVSRRLLADGETPVGVYRKLAGGPGTFLLESAEHGGVWSRYSFVGVRAAATLTERDG
QAAWTDGTPPPGVPLDGDPLDVLRAVERQLCSARPSGTPPLLGGLVGYLSYDIVRRIERLPARATDDLGMPELRMLLTTD
LAVLDHTDGSCQLVANIFTGAGDPADPAEAADLAGPGAAGGPSARRAELDAAYDDAVHRIEVMTADLGKWSEPTVATTTG
ASTGVRDFASATPPGGFHAAVERSIEEIRAGECFQIVVSQRFERPTTADALDVYRVLRASNPSPYMYLLRFADHDVVGSS
PEAHVKVTGRRALLHPIAGSRPRGETPERDAELAAQLLADPKERSEHVMLVDLVRNDLGRVCVPGSVRVVEFASVERFSH
IMHIVSTVIGEVAPERSAVDVLAATFPAGTLSGAPKVRAMEIIDELEPTRRGLYGGVVGYLDFGGDLDTAIAIRTAVLRS
GMAYVQAGAGIVADSVPDTEDLESRTKAAAVLRAIEVAESLRPPV
>Mature_524_residues
TTGEITPSRAEFHELAARQPVVAVSRRLLADGETPVGVYRKLAGGPGTFLLESAEHGGVWSRYSFVGVRAAATLTERDGQ
AAWTDGTPPPGVPLDGDPLDVLRAVERQLCSARPSGTPPLLGGLVGYLSYDIVRRIERLPARATDDLGMPELRMLLTTDL
AVLDHTDGSCQLVANIFTGAGDPADPAEAADLAGPGAAGGPSARRAELDAAYDDAVHRIEVMTADLGKWSEPTVATTTGA
STGVRDFASATPPGGFHAAVERSIEEIRAGECFQIVVSQRFERPTTADALDVYRVLRASNPSPYMYLLRFADHDVVGSSP
EAHVKVTGRRALLHPIAGSRPRGETPERDAELAAQLLADPKERSEHVMLVDLVRNDLGRVCVPGSVRVVEFASVERFSHI
MHIVSTVIGEVAPERSAVDVLAATFPAGTLSGAPKVRAMEIIDELEPTRRGLYGGVVGYLDFGGDLDTAIAIRTAVLRSG
MAYVQAGAGIVADSVPDTEDLESRTKAAAVLRAIEVAESLRPPV

Specific function: Tryptophan biosynthesis; first step. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1787518, Length=445, Percent_Identity=38.4269662921348, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI1788114, Length=479, Percent_Identity=30.6889352818372, Blast_Score=228, Evalue=7e-61,
Organism=Escherichia coli, GI1786809, Length=247, Percent_Identity=31.5789473684211, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87082077, Length=261, Percent_Identity=23.7547892720307, Blast_Score=63, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320935, Length=499, Percent_Identity=36.2725450901804, Blast_Score=281, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6324361, Length=429, Percent_Identity=25.1748251748252, Blast_Score=108, Evalue=3e-24,

Paralogues:

None

Copy number: 700 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR005256
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 55624; Mature: 55493

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTGEITPSRAEFHELAARQPVVAVSRRLLADGETPVGVYRKLAGGPGTFLLESAEHGGV
CCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEECCCCCCC
WSRYSFVGVRAAATLTERDGQAAWTDGTPPPGVPLDGDPLDVLRAVERQLCSARPSGTPP
CHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCH
LLGGLVGYLSYDIVRRIERLPARATDDLGMPELRMLLTTDLAVLDHTDGSCQLVANIFTG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCHHHHHHHHHC
AGDPADPAEAADLAGPGAAGGPSARRAELDAAYDDAVHRIEVMTADLGKWSEPTVATTTG
CCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEECC
ASTGVRDFASATPPGGFHAAVERSIEEIRAGECFQIVVSQRFERPTTADALDVYRVLRAS
CCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCC
NPSPYMYLLRFADHDVVGSSPEAHVKVTGRRALLHPIAGSRPRGETPERDAELAAQLLAD
CCCCEEEEEEECCCCCCCCCCCCEEEECCCHHEECCCCCCCCCCCCCCHHHHHHHHHHCC
PKERSEHVMLVDLVRNDLGRVCVPGSVRVVEFASVERFSHIMHIVSTVIGEVAPERSAVD
HHHHCCCEEEHHHHHHHCCCEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
VLAATFPAGTLSGAPKVRAMEIIDELEPTRRGLYGGVVGYLDFGGDLDTAIAIRTAVLRS
HHHHHCCCCCCCCCCCHHHHHHHHHHCHHHHHHHCCHHEEEECCCCHHHHHHHHHHHHHC
GMAYVQAGAGIVADSVPDTEDLESRTKAAAVLRAIEVAESLRPPV
CHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTGEITPSRAEFHELAARQPVVAVSRRLLADGETPVGVYRKLAGGPGTFLLESAEHGGV
CCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEECCCCCCC
WSRYSFVGVRAAATLTERDGQAAWTDGTPPPGVPLDGDPLDVLRAVERQLCSARPSGTPP
CHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCH
LLGGLVGYLSYDIVRRIERLPARATDDLGMPELRMLLTTDLAVLDHTDGSCQLVANIFTG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCHHHHHHHHHC
AGDPADPAEAADLAGPGAAGGPSARRAELDAAYDDAVHRIEVMTADLGKWSEPTVATTTG
CCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEECC
ASTGVRDFASATPPGGFHAAVERSIEEIRAGECFQIVVSQRFERPTTADALDVYRVLRAS
CCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCC
NPSPYMYLLRFADHDVVGSSPEAHVKVTGRRALLHPIAGSRPRGETPERDAELAAQLLAD
CCCCEEEEEEECCCCCCCCCCCCEEEECCCHHEECCCCCCCCCCCCCCHHHHHHHHHHCC
PKERSEHVMLVDLVRNDLGRVCVPGSVRVVEFASVERFSHIMHIVSTVIGEVAPERSAVD
HHHHCCCEEEHHHHHHHCCCEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
VLAATFPAGTLSGAPKVRAMEIIDELEPTRRGLYGGVVGYLDFGGDLDTAIAIRTAVLRS
HHHHHCCCCCCCCCCCHHHHHHHHHHCHHHHHHHCCHHEEEECCCCHHHHHHHHHHHHHC
GMAYVQAGAGIVADSVPDTEDLESRTKAAAVLRAIEVAESLRPPV
CHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA