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The map label for this gene is perR [H]

Identifier: 158313642

GI number: 158313642

Start: 2169157

End: 2169582

Strand: Direct

Name: perR [H]

Synonym: Franean1_1806

Alternate gene names: 158313642

Gene position: 2169157-2169582 (Clockwise)

Preceding gene: 158313639

Following gene: 158313643

Centisome position: 24.15

GC content: 73.24

Gene sequence:

>426_bases
ATGCCGGAGCGGACCGAACTACGTCTCACCCCCCAGCGCACCCGTGTGCTGGAGGTGCTGAAGGCCGCCGAGGACCATCC
GACGGCGGCCGAGGTCTACGAGCGTGTGCGGCTCGCGGCCCCCGGGATCGGCAGCGCGACCGTCTACCGCGCCCTCGCGT
TGCTCGTCGAGACCGGGCACGCCCTCGAGCTCAATCTCGGGGACGGCGCGGCCGCCAGGTACGACGCCAACACCAGCCGG
CACGACCACGCCGTGTGCGAGCGGTGCGGCCGGGCCGCGGACATCGACCACCCCGTCCCGGACGGCATGGTGGCCGAGAT
CGCGCGCCGGTCCGGTTTCACGATCACCGGGTACGACCTGCAGTTCAGGGGCCTGTGCCCGGAGTGTCAGACCGCCGGCG
AGGGCCATCGCCCGGGCCGACGGTAG

Upstream 100 bases:

>100_bases
CAGTCCCGACGTTCGCCCGTTGCCGCGGACACACCGACACACGGCACCGGGACGCGGGACGAACGCCCCGGGCGGCGCCG
ACCGATGACGGACGTGATCG

Downstream 100 bases:

>100_bases
GACCCGACACCCATCACGTAGGAGGAGTACCGCATGCCGAAGCTTGACGGCACCAAGACCCACGAGAACCTCAAGGAGGC
GTTCGCCGGCGAGAGCCAGG

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MPERTELRLTPQRTRVLEVLKAAEDHPTAAEVYERVRLAAPGIGSATVYRALALLVETGHALELNLGDGAAARYDANTSR
HDHAVCERCGRAADIDHPVPDGMVAEIARRSGFTITGYDLQFRGLCPECQTAGEGHRPGRR

Sequences:

>Translated_141_residues
MPERTELRLTPQRTRVLEVLKAAEDHPTAAEVYERVRLAAPGIGSATVYRALALLVETGHALELNLGDGAAARYDANTSR
HDHAVCERCGRAADIDHPVPDGMVAEIARRSGFTITGYDLQFRGLCPECQTAGEGHRPGRR
>Mature_140_residues
PERTELRLTPQRTRVLEVLKAAEDHPTAAEVYERVRLAAPGIGSATVYRALALLVETGHALELNLGDGAAARYDANTSRH
DHAVCERCGRAADIDHPVPDGMVAEIARRSGFTITGYDLQFRGLCPECQTAGEGHRPGRR

Specific function: Manganese-dependent repressor that controls a regulon of oxidative stress resistance and iron-storage proteins. May act as a hydrogen peroxide and organic hydroperoxide sensor [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=123, Percent_Identity=30.8943089430894, Blast_Score=64, Evalue=3e-12,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 15357; Mature: 15226

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPERTELRLTPQRTRVLEVLKAAEDHPTAAEVYERVRLAAPGIGSATVYRALALLVETGH
CCCCCCEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
ALELNLGDGAAARYDANTSRHDHAVCERCGRAADIDHPVPDGMVAEIARRSGFTITGYDL
EEEEECCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCE
QFRGLCPECQTAGEGHRPGRR
EECCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure 
PERTELRLTPQRTRVLEVLKAAEDHPTAAEVYERVRLAAPGIGSATVYRALALLVETGH
CCCCCEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
ALELNLGDGAAARYDANTSRHDHAVCERCGRAADIDHPVPDGMVAEIARRSGFTITGYDL
EEEEECCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCE
QFRGLCPECQTAGEGHRPGRR
EECCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA