| Definition | Frankia sp. EAN1pec chromosome, complete genome. |
|---|---|
| Accession | NC_009921 |
| Length | 8,982,042 |
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The map label for this gene is alaS [H]
Identifier: 158313530
GI number: 158313530
Start: 2025168
End: 2027846
Strand: Direct
Name: alaS [H]
Synonym: Franean1_1694
Alternate gene names: 158313530
Gene position: 2025168-2027846 (Clockwise)
Preceding gene: 158313529
Following gene: 158313531
Centisome position: 22.55
GC content: 72.3
Gene sequence:
>2679_bases GTGCCTTATCCCGACGACCCTGGACGACGTGAACCGATGGACACGGCCGAGATCCGCCGCCGCTTTCTGAACCATTTCTC CGAGCGGGGTCACACCGTGGTCCCGAGTGCGTCCCTGGTGGCGCAGGACCCGACCCTGCTGCTGGTGAACGCCGGCATGG TTCCCTTCAAGCCCTACTTCCTCGGGGACCTGAAGGCGCCGTGGAACCGTGCGACCAGCGTGCAGAAATGCGTGCGGACC GTGGACATCGACAACGTCGGCCGCACCGCCCGACACGCCTCCTTCTTCCAGATGTGCGGGAACTTCTCCTTCGGTGACTA CTTCAAGGCCGAGGCGATCCCGTTCGCCTTCGAGCTGATCGTCGACGGCTACGGCTTCAACCCCGACGACCTGTGGGCCA CCGTCTACCTGGACGACGACGAGGCCGAGGCGATTTGGCGCACCCTGCTGCCCGCCGAGCGCATCCAGCGGCGCGGCAAG AAGGACAACTTCTGGTCGATGGGTGTGCCCGGCCCGTGCGGCCCGTGCAGCGAGATCTACTTCGACCGCGGCCCGGCGTA CGGGCGCGAGGGCGGCCCGGAGGCGGACGAGGACCGCTACCTGGAGATCTGGAACCTCGTCTTCATGCAGTTCGCGCGGG GCGAGGGCAGCGAGTACGGCTACGAGATCGTCGGTGATCTGCCCGCCCGCAACATCGACACCGGGATGGGCCTGGAGCGG ATGGCCACCATCCTGCAGGGTGTCGAGAACCTGTACGAGATCGACATCTCCCGTCCGGTGCTCGACGCGGCCGGCCGGCT CACCGGCACCCGCTACGGCGCCGACCCGGATTCCGACGTCCGGCTGCGGGTCGTCGCCGACCACACCCGGACCGCGGCGA TGCTGATCTCGGACGGGGTCTCGCCGTCCAACGAGGGCCGCGGGTACGTCCTGCGGCGGATGCTGCGCCGGGCGGTGCGT GACGCCCGGCTGCTGGGCGCCCGTGAGCCGGTCATGGACGAGCTGTTCGGCGTGGTCCGCGCGGCGATGGGCCCGATCTA CCCGGAGCTCGTCGACCAGGCCGAGGCGATCACGGCGGTCGCGGTCGCCGAGGAGACGGCTTTCCTGGAGACGCTGCGCA CGGGCACCACCCTCTTCGACACCGCGGTCACCCAGGCCCGGTCCAGCGGGTCGTCCCAGCTCAGCGGCGAGTCGGCGTTC CGGCTGCACGACACCTACGGGTTCCCGATCGACCTGACCATGGACATGGCGGCCGACGCGGGCCTGACCGTGGACGAGGC CGGCTTCCGCCGGCTGATGGAGCGCCAGCGCCAGGCGGCGAAGGCCGACCGGGCGTCCCGCCGCATCGGCAACCTGGACC TCTCCGCCTTCCGGCCGATCCTCGCCGCCTCCGGCCCGACGACGTTCACCGGCTACACCGAGCTCGGGCGCGAGTCGGGC ATCGTCGGCATCGTCGGCATCGGCGACGGCGACAGCCTGACCGCGGCCGGCGAGGGGGAGGAGGTCGGCATCCTGCTCGA CGCGACCCCCTTCTACGCCGAGAGCGGTGGCCAGGAGGCCGACCTGGGCCGGATCCGGTTCGACGGCGGCGAGGCCGAGG TGCTCGACGTCCAGCGCCCGGTGCCCGACCTGGTCATGCACCGGGTGAAGGTGCTCGGTGGCGAGCTGCGTGTCGGCGCG GACGTGTTCGCCGAGGTGGACGTCGAGCGCCGGCGCGCGGTGTCGCGCTCGCACACCGCCACCCACCTCGTGCACACCGC GTTCCGCCGGGCGCTCGGGGAGTCGGCGACGCAGGCCGGGTCGCTGAACTCGCCGGGCCGGCTGCGCTTCGACTTCCACG CGCTCGGCGCGGTGCCCGACTCCGTCCTCGCCGACGTCGAGGACGAGGTCAACGAGATCGCCCTGCGTGATCTGGAGGTC CGCTGGTACGTCACCTCTCAGGAGGAGGCGCGCCGGCTGGGCGCGATGGCGCTGTTCGGCGAGAAGTACGGCGACCGGGT CCGTGTCGTGGACGTCGGGGACTACGCCCGCGAGCTGTGCGGTGGTACCCATGTGGCCAGCTCGGCCCAGCTTGGCGCGA TCAAGCTGCTGTCCGAGTCGTCGATCTCGGCCGGGACGCGCCGGGTGGAGGCGCTGGTCGGCATGGATGCCTTCCGGTTC CTGGCCCGCGAGCACGTGCTCGTCTCGCAGCTCTCCAGCACGCTCAAGGCCCGTCCGGACGAGCTCGCCGACCGGGTCGC CGACATCGTCGGGCGGCTGCGAGACGCGGAGAAGGAGCTGGAGCGGCTGCGGGCACAGGCGGTGCTGGCCGGCTCGGCGG CGCTCGCCGCCGGCGCCGAGGACGTGGGGGGCGTGGCGCTGGTCACCGCGCAGGTGCCCGCGGGCACTCCGGCAGACGAC GTCCGCCTGCTCGCCCTGGATGTGCGCGGCCGGCTCGCCGGCCGGCCGGCGGTGGTCGCGGTCGTCGAGGCCGCCGGCGC GGCAGTCGTCGTGGCGACCGACGAGACCGCGCGGACCCGCGGCCTGCGGGCCGGCGACCTGGTCCGGCACTCCTGGGCCG CGCTCGGAGGCAAGGGCGGCGGCAAGCCTGACGTCGCCCAGGGCGGACGCGGTGACGCGGACATGATCCCGAAGGTCTTC GCCCGGCTGCGCGAGCTGGTCGCCGACCAGAGCGCGTGA
Upstream 100 bases:
>100_bases GGAACGGACGATGCGTCTGGTCCCCGGCGCGCGCCGGCCATGACCTCCGACCGGTCACGGCCGATCCCGGGTACACGCCC GGCGTCGGCCGGGTGGCCGG
Downstream 100 bases:
>100_bases ACGACACCGGTGTGGGCCGGGGGGACACCGGCGGCGCGGCCGCGGCGTCGCCCTGGCCCGGCCCGGACCCCGTGACCGCT CCGGACCCCGTGACCGCTCC
Product: alanyl-tRNA synthetase
Products: NA
Alternate protein names: Alanine--tRNA ligase; AlaRS [H]
Number of amino acids: Translated: 892; Mature: 891
Protein sequence:
>892_residues MPYPDDPGRREPMDTAEIRRRFLNHFSERGHTVVPSASLVAQDPTLLLVNAGMVPFKPYFLGDLKAPWNRATSVQKCVRT VDIDNVGRTARHASFFQMCGNFSFGDYFKAEAIPFAFELIVDGYGFNPDDLWATVYLDDDEAEAIWRTLLPAERIQRRGK KDNFWSMGVPGPCGPCSEIYFDRGPAYGREGGPEADEDRYLEIWNLVFMQFARGEGSEYGYEIVGDLPARNIDTGMGLER MATILQGVENLYEIDISRPVLDAAGRLTGTRYGADPDSDVRLRVVADHTRTAAMLISDGVSPSNEGRGYVLRRMLRRAVR DARLLGAREPVMDELFGVVRAAMGPIYPELVDQAEAITAVAVAEETAFLETLRTGTTLFDTAVTQARSSGSSQLSGESAF RLHDTYGFPIDLTMDMAADAGLTVDEAGFRRLMERQRQAAKADRASRRIGNLDLSAFRPILAASGPTTFTGYTELGRESG IVGIVGIGDGDSLTAAGEGEEVGILLDATPFYAESGGQEADLGRIRFDGGEAEVLDVQRPVPDLVMHRVKVLGGELRVGA DVFAEVDVERRRAVSRSHTATHLVHTAFRRALGESATQAGSLNSPGRLRFDFHALGAVPDSVLADVEDEVNEIALRDLEV RWYVTSQEEARRLGAMALFGEKYGDRVRVVDVGDYARELCGGTHVASSAQLGAIKLLSESSISAGTRRVEALVGMDAFRF LAREHVLVSQLSSTLKARPDELADRVADIVGRLRDAEKELERLRAQAVLAGSAALAAGAEDVGGVALVTAQVPAGTPADD VRLLALDVRGRLAGRPAVVAVVEAAGAAVVVATDETARTRGLRAGDLVRHSWAALGGKGGGKPDVAQGGRGDADMIPKVF ARLRELVADQSA
Sequences:
>Translated_892_residues MPYPDDPGRREPMDTAEIRRRFLNHFSERGHTVVPSASLVAQDPTLLLVNAGMVPFKPYFLGDLKAPWNRATSVQKCVRT VDIDNVGRTARHASFFQMCGNFSFGDYFKAEAIPFAFELIVDGYGFNPDDLWATVYLDDDEAEAIWRTLLPAERIQRRGK KDNFWSMGVPGPCGPCSEIYFDRGPAYGREGGPEADEDRYLEIWNLVFMQFARGEGSEYGYEIVGDLPARNIDTGMGLER MATILQGVENLYEIDISRPVLDAAGRLTGTRYGADPDSDVRLRVVADHTRTAAMLISDGVSPSNEGRGYVLRRMLRRAVR DARLLGAREPVMDELFGVVRAAMGPIYPELVDQAEAITAVAVAEETAFLETLRTGTTLFDTAVTQARSSGSSQLSGESAF RLHDTYGFPIDLTMDMAADAGLTVDEAGFRRLMERQRQAAKADRASRRIGNLDLSAFRPILAASGPTTFTGYTELGRESG IVGIVGIGDGDSLTAAGEGEEVGILLDATPFYAESGGQEADLGRIRFDGGEAEVLDVQRPVPDLVMHRVKVLGGELRVGA DVFAEVDVERRRAVSRSHTATHLVHTAFRRALGESATQAGSLNSPGRLRFDFHALGAVPDSVLADVEDEVNEIALRDLEV RWYVTSQEEARRLGAMALFGEKYGDRVRVVDVGDYARELCGGTHVASSAQLGAIKLLSESSISAGTRRVEALVGMDAFRF LAREHVLVSQLSSTLKARPDELADRVADIVGRLRDAEKELERLRAQAVLAGSAALAAGAEDVGGVALVTAQVPAGTPADD VRLLALDVRGRLAGRPAVVAVVEAAGAAVVVATDETARTRGLRAGDLVRHSWAALGGKGGGKPDVAQGGRGDADMIPKVF ARLRELVADQSA >Mature_891_residues PYPDDPGRREPMDTAEIRRRFLNHFSERGHTVVPSASLVAQDPTLLLVNAGMVPFKPYFLGDLKAPWNRATSVQKCVRTV DIDNVGRTARHASFFQMCGNFSFGDYFKAEAIPFAFELIVDGYGFNPDDLWATVYLDDDEAEAIWRTLLPAERIQRRGKK DNFWSMGVPGPCGPCSEIYFDRGPAYGREGGPEADEDRYLEIWNLVFMQFARGEGSEYGYEIVGDLPARNIDTGMGLERM ATILQGVENLYEIDISRPVLDAAGRLTGTRYGADPDSDVRLRVVADHTRTAAMLISDGVSPSNEGRGYVLRRMLRRAVRD ARLLGAREPVMDELFGVVRAAMGPIYPELVDQAEAITAVAVAEETAFLETLRTGTTLFDTAVTQARSSGSSQLSGESAFR LHDTYGFPIDLTMDMAADAGLTVDEAGFRRLMERQRQAAKADRASRRIGNLDLSAFRPILAASGPTTFTGYTELGRESGI VGIVGIGDGDSLTAAGEGEEVGILLDATPFYAESGGQEADLGRIRFDGGEAEVLDVQRPVPDLVMHRVKVLGGELRVGAD VFAEVDVERRRAVSRSHTATHLVHTAFRRALGESATQAGSLNSPGRLRFDFHALGAVPDSVLADVEDEVNEIALRDLEVR WYVTSQEEARRLGAMALFGEKYGDRVRVVDVGDYARELCGGTHVASSAQLGAIKLLSESSISAGTRRVEALVGMDAFRFL AREHVLVSQLSSTLKARPDELADRVADIVGRLRDAEKELERLRAQAVLAGSAALAAGAEDVGGVALVTAQVPAGTPADDV RLLALDVRGRLAGRPAVVAVVEAAGAAVVVATDETARTRGLRAGDLVRHSWAALGGKGGGKPDVAQGGRGDADMIPKVFA RLRELVADQSA
Specific function: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction:alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editin
COG id: COG0013
COG function: function code J; Alanyl-tRNA synthetase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]
Homologues:
Organism=Homo sapiens, GI109148542, Length=989, Percent_Identity=33.7714863498483, Blast_Score=416, Evalue=1e-116, Organism=Homo sapiens, GI38569417, Length=817, Percent_Identity=34.8837209302326, Blast_Score=350, Evalue=4e-96, Organism=Escherichia coli, GI1789048, Length=880, Percent_Identity=42.7272727272727, Blast_Score=627, Evalue=0.0, Organism=Caenorhabditis elegans, GI17506981, Length=954, Percent_Identity=36.3731656184486, Blast_Score=458, Evalue=1e-129, Organism=Caenorhabditis elegans, GI17536681, Length=756, Percent_Identity=31.4814814814815, Blast_Score=322, Evalue=4e-88, Organism=Saccharomyces cerevisiae, GI6324911, Length=767, Percent_Identity=36.1147327249022, Blast_Score=446, Evalue=1e-126, Organism=Drosophila melanogaster, GI24582809, Length=961, Percent_Identity=32.258064516129, Blast_Score=424, Evalue=1e-118, Organism=Drosophila melanogaster, GI45552267, Length=961, Percent_Identity=32.258064516129, Blast_Score=424, Evalue=1e-118, Organism=Drosophila melanogaster, GI24658214, Length=845, Percent_Identity=29.4674556213018, Blast_Score=297, Evalue=2e-80,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002318 - InterPro: IPR018162 - InterPro: IPR018165 - InterPro: IPR018164 - InterPro: IPR023033 - InterPro: IPR018163 - InterPro: IPR012947 [H]
Pfam domain/function: PF01411 tRNA-synt_2c; PF07973 tRNA_SAD [H]
EC number: =6.1.1.7 [H]
Molecular weight: Translated: 96355; Mature: 96224
Theoretical pI: Translated: 4.86; Mature: 4.86
Prosite motif: PS50860 AA_TRNA_LIGASE_II_ALA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPYPDDPGRREPMDTAEIRRRFLNHFSERGHTVVPSASLVAQDPTLLLVNAGMVPFKPYF CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCHHEECCCCEEEEECCCCCCCCHH LGDLKAPWNRATSVQKCVRTVDIDNVGRTARHASFFQMCGNFSFGDYFKAEAIPFAFELI CCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCEEEEEE VDGYGFNPDDLWATVYLDDDEAEAIWRTLLPAERIQRRGKKDNFWSMGVPGPCGPCSEIY ECCCCCCCCCEEEEEEECCCHHHHHHHHHCCHHHHHHCCCCCCCEECCCCCCCCCCHHHH FDRGPAYGREGGPEADEDRYLEIWNLVFMQFARGEGSEYGYEIVGDLPARNIDTGMGLER CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHH MATILQGVENLYEIDISRPVLDAAGRLTGTRYGADPDSDVRLRVVADHTRTAAMLISDGV HHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCHHEEHHEECCC SPSNEGRGYVLRRMLRRAVRDARLLGAREPVMDELFGVVRAAMGPIYPELVDQAEAITAV CCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH AVAEETAFLETLRTGTTLFDTAVTQARSSGSSQLSGESAFRLHDTYGFPIDLTMDMAADA HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCC GLTVDEAGFRRLMERQRQAAKADRASRRIGNLDLSAFRPILAASGPTTFTGYTELGRESG CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHCCCC IVGIVGIGDGDSLTAAGEGEEVGILLDATPFYAESGGQEADLGRIRFDGGEAEVLDVQRP CEEEEEECCCCCEEECCCCCEEEEEEECCCCHHCCCCCCCCCCEEEECCCCEEEEECCCC VPDLVMHRVKVLGGELRVGADVFAEVDVERRRAVSRSHTATHLVHTAFRRALGESATQAG CHHHHHHHHHHHCCCEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC SLNSPGRLRFDFHALGAVPDSVLADVEDEVNEIALRDLEVRWYVTSQEEARRLGAMALFG CCCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCHHHHHHHHHHHHHH EKYGDRVRVVDVGDYARELCGGTHVASSAQLGAIKLLSESSISAGTRRVEALVGMDAFRF HHCCCEEEEEECCHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH LAREHVLVSQLSSTLKARPDELADRVADIVGRLRDAEKELERLRAQAVLAGSAALAAGAE HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCC DVGGVALVTAQVPAGTPADDVRLLALDVRGRLAGRPAVVAVVEAAGAAVVVATDETARTR CCCCEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCEEEEEECCCCEEEEEECCHHHHC GLRAGDLVRHSWAALGGKGGGKPDVAQGGRGDADMIPKVFARLRELVADQSA CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC >Mature Secondary Structure PYPDDPGRREPMDTAEIRRRFLNHFSERGHTVVPSASLVAQDPTLLLVNAGMVPFKPYF CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCHHEECCCCEEEEECCCCCCCCHH LGDLKAPWNRATSVQKCVRTVDIDNVGRTARHASFFQMCGNFSFGDYFKAEAIPFAFELI CCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCEEEEEE VDGYGFNPDDLWATVYLDDDEAEAIWRTLLPAERIQRRGKKDNFWSMGVPGPCGPCSEIY ECCCCCCCCCEEEEEEECCCHHHHHHHHHCCHHHHHHCCCCCCCEECCCCCCCCCCHHHH FDRGPAYGREGGPEADEDRYLEIWNLVFMQFARGEGSEYGYEIVGDLPARNIDTGMGLER CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHH MATILQGVENLYEIDISRPVLDAAGRLTGTRYGADPDSDVRLRVVADHTRTAAMLISDGV HHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCHHEEHHEECCC SPSNEGRGYVLRRMLRRAVRDARLLGAREPVMDELFGVVRAAMGPIYPELVDQAEAITAV CCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH AVAEETAFLETLRTGTTLFDTAVTQARSSGSSQLSGESAFRLHDTYGFPIDLTMDMAADA HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCC GLTVDEAGFRRLMERQRQAAKADRASRRIGNLDLSAFRPILAASGPTTFTGYTELGRESG CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHCCCC IVGIVGIGDGDSLTAAGEGEEVGILLDATPFYAESGGQEADLGRIRFDGGEAEVLDVQRP CEEEEEECCCCCEEECCCCCEEEEEEECCCCHHCCCCCCCCCCEEEECCCCEEEEECCCC VPDLVMHRVKVLGGELRVGADVFAEVDVERRRAVSRSHTATHLVHTAFRRALGESATQAG CHHHHHHHHHHHCCCEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC SLNSPGRLRFDFHALGAVPDSVLADVEDEVNEIALRDLEVRWYVTSQEEARRLGAMALFG CCCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCHHHHHHHHHHHHHH EKYGDRVRVVDVGDYARELCGGTHVASSAQLGAIKLLSESSISAGTRRVEALVGMDAFRF HHCCCEEEEEECCHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH LAREHVLVSQLSSTLKARPDELADRVADIVGRLRDAEKELERLRAQAVLAGSAALAAGAE HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCC DVGGVALVTAQVPAGTPADDVRLLALDVRGRLAGRPAVVAVVEAAGAAVVVATDETARTR CCCCEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCEEEEEECCCCEEEEEECCHHHHC GLRAGDLVRHSWAALGGKGGGKPDVAQGGRGDADMIPKVFARLRELVADQSA CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA