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The map label for this gene is acdA [H]

Identifier: 158313462

GI number: 158313462

Start: 1942343

End: 1943611

Strand: Direct

Name: acdA [H]

Synonym: Franean1_1625

Alternate gene names: 158313462

Gene position: 1942343-1943611 (Clockwise)

Preceding gene: 158313461

Following gene: 158313464

Centisome position: 21.62

GC content: 71.71

Gene sequence:

>1269_bases
ATGAGCACGGGCGACATCGAGGACGTCGAGACCTTCCGCCGCCGGGCGCGGGACTGGATCCGGGCCAACCTCGCGCCGCT
CCCGGCGGGCAGCGGGATCGGCGTGATGCGCGCGGGTGCCAGCGACGAGGCGGAGCTCGCCGCGGTCGCGCGCCAGCGCG
AGATCCAGCGGATGTTCTTCGACGCGGGTTTCGCCGGGATCGCCTTCCCCCGTGAATACGGCGGCCAGGGGCTCACCCCG
GACCACCAGCGGGCCTTCAGCGAGGAGATCTCGGGCTACGAGTATCCCGCGGACATCCAGGCGCCGACCTTCTCTCCGTG
CGCCGCGGTGCTGCTCGACTTCGGCACCGAGGAGCAGAAGCGCCAGCACATCCCGGCCATTCTGAAGGGCGAGGAGCTGT
GGATGCAGTTCCTGTCCGAGCCGAGCGCCGGTTCGGACGTCGCCGCCGCGCTGACCAGTGCCGTCCGCGACGGTGACGAC
TGGATCCTGAACGGGTCCAAGATCTGGACGACCGGCGCCTGGTGGTCGGACTGGGGCCTCGTCCTGGCCCGGACGAACTG
GGACGTCCCGAAGCACCGCGGGCTGACCGTGTTCATCCTGCCGATTCACCAGCCGGGTATCGAGGTGCACCGCATCGAGA
TGCTGAACGGCAACAAGGAGTTCTGCCAGGAGTTCCTCACCGACGTGCGGGTCCCGGACTCCGACCGCATCGGCGAGGTC
GACGACGGCTGGACGGTCGGCACGCGGTGGATGTTCCACGAGCGGATGCTGCACAACTCGCCGCTCGTCACCATTCCCGC
CGACGGGGCGCGCGGCACGATCCGCGCCACCCACCTGGTGGAGATCGCGCGCGACGCCGGCCGGCTCGACGACCCGTTGG
CGCGCGACCTCATCGGTGAGGGCCGCATGCTCGACCTCGTCACGCACGCGCTGCAGGGGCGGCTGTCCCGCGGCCTGCGG
TCCGGCCGGATGCCCGACCAGTCGGCGGCCATCGGACGGCTGTTCACCGGTGTGACGGCCGCGCGGACCACGACCCTGTC
GTTCAACCTGGCCGGCGGGGCGAGCGCGGCCTGGACGGACGACGACGGCGCCACCGCCGAGTGCGGCAACGACTTCCTGC
TGCGGCAGGTGAGCTGCATCGGCGGCGGCACCACCGAGATGGCCCGCAACGTTGTCAGCGAGCGGGTGCTCGGCATGCCC
CGCGAGCCGGCGAAGGACCGCGGGGTGGCCTTCCGGGACGTCCCGCGGGGCGCCTCGAACCGGGGCTGA

Upstream 100 bases:

>100_bases
TTTTCCTGCGCCGGGTCGTCCTCGACCGCGCGCTGTACGGCACCCCCGCCGAGCACCGGCAGCGGATCGCCGGCGTGGTC
GAACATCTCAAGGAGCGGGC

Downstream 100 bases:

>100_bases
CCCCACCGATCCGTGACACCGGCCGGGCGCGTACCCACGCGCCCGGCCGCTGTCGTTCGTCCGGCTGTCTCGTCCGGCTG
TCGCTCGTCCGCTCTCGTTC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MSTGDIEDVETFRRRARDWIRANLAPLPAGSGIGVMRAGASDEAELAAVARQREIQRMFFDAGFAGIAFPREYGGQGLTP
DHQRAFSEEISGYEYPADIQAPTFSPCAAVLLDFGTEEQKRQHIPAILKGEELWMQFLSEPSAGSDVAAALTSAVRDGDD
WILNGSKIWTTGAWWSDWGLVLARTNWDVPKHRGLTVFILPIHQPGIEVHRIEMLNGNKEFCQEFLTDVRVPDSDRIGEV
DDGWTVGTRWMFHERMLHNSPLVTIPADGARGTIRATHLVEIARDAGRLDDPLARDLIGEGRMLDLVTHALQGRLSRGLR
SGRMPDQSAAIGRLFTGVTAARTTTLSFNLAGGASAAWTDDDGATAECGNDFLLRQVSCIGGGTTEMARNVVSERVLGMP
REPAKDRGVAFRDVPRGASNRG

Sequences:

>Translated_422_residues
MSTGDIEDVETFRRRARDWIRANLAPLPAGSGIGVMRAGASDEAELAAVARQREIQRMFFDAGFAGIAFPREYGGQGLTP
DHQRAFSEEISGYEYPADIQAPTFSPCAAVLLDFGTEEQKRQHIPAILKGEELWMQFLSEPSAGSDVAAALTSAVRDGDD
WILNGSKIWTTGAWWSDWGLVLARTNWDVPKHRGLTVFILPIHQPGIEVHRIEMLNGNKEFCQEFLTDVRVPDSDRIGEV
DDGWTVGTRWMFHERMLHNSPLVTIPADGARGTIRATHLVEIARDAGRLDDPLARDLIGEGRMLDLVTHALQGRLSRGLR
SGRMPDQSAAIGRLFTGVTAARTTTLSFNLAGGASAAWTDDDGATAECGNDFLLRQVSCIGGGTTEMARNVVSERVLGMP
REPAKDRGVAFRDVPRGASNRG
>Mature_421_residues
STGDIEDVETFRRRARDWIRANLAPLPAGSGIGVMRAGASDEAELAAVARQREIQRMFFDAGFAGIAFPREYGGQGLTPD
HQRAFSEEISGYEYPADIQAPTFSPCAAVLLDFGTEEQKRQHIPAILKGEELWMQFLSEPSAGSDVAAALTSAVRDGDDW
ILNGSKIWTTGAWWSDWGLVLARTNWDVPKHRGLTVFILPIHQPGIEVHRIEMLNGNKEFCQEFLTDVRVPDSDRIGEVD
DGWTVGTRWMFHERMLHNSPLVTIPADGARGTIRATHLVEIARDAGRLDDPLARDLIGEGRMLDLVTHALQGRLSRGLRS
GRMPDQSAAIGRLFTGVTAARTTTLSFNLAGGASAAWTDDDGATAECGNDFLLRQVSCIGGGTTEMARNVVSERVLGMPR
EPAKDRGVAFRDVPRGASNRG

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=347, Percent_Identity=26.5129682997118, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI226958414, Length=349, Percent_Identity=26.0744985673352, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI7656849, Length=316, Percent_Identity=27.2151898734177, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4557233, Length=220, Percent_Identity=30, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI4501857, Length=170, Percent_Identity=29.4117647058824, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI76496475, Length=307, Percent_Identity=27.6872964169381, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4557235, Length=310, Percent_Identity=27.741935483871, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI187960098, Length=292, Percent_Identity=26.7123287671233, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4557231, Length=292, Percent_Identity=26.7123287671233, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4501859, Length=200, Percent_Identity=29, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI21361497, Length=197, Percent_Identity=28.9340101522843, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI87081958, Length=362, Percent_Identity=28.1767955801105, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1786223, Length=144, Percent_Identity=29.8611111111111, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17508101, Length=350, Percent_Identity=27.7142857142857, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17534899, Length=203, Percent_Identity=34.9753694581281, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17569725, Length=372, Percent_Identity=27.6881720430108, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17505929, Length=208, Percent_Identity=31.25, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71990804, Length=199, Percent_Identity=31.6582914572864, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17538396, Length=214, Percent_Identity=29.4392523364486, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17570075, Length=371, Percent_Identity=25.8760107816712, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17551932, Length=352, Percent_Identity=26.1363636363636, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17506239, Length=195, Percent_Identity=29.7435897435897, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32563615, Length=190, Percent_Identity=30.5263157894737, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17533517, Length=188, Percent_Identity=27.6595744680851, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=218, Percent_Identity=30.2752293577982, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24646207, Length=413, Percent_Identity=25.6658595641646, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21356377, Length=203, Percent_Identity=33.0049261083744, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21355753, Length=407, Percent_Identity=26.7813267813268, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24666513, Length=237, Percent_Identity=28.6919831223629, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24660351, Length=130, Percent_Identity=36.9230769230769, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281363737, Length=308, Percent_Identity=24.3506493506494, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 46122; Mature: 45991

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTGDIEDVETFRRRARDWIRANLAPLPAGSGIGVMRAGASDEAELAAVARQREIQRMFF
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHH
DAGFAGIAFPREYGGQGLTPDHQRAFSEEISGYEYPADIQAPTFSPCAAVLLDFGTEEQK
HCCCCCCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCHHH
RQHIPAILKGEELWMQFLSEPSAGSDVAAALTSAVRDGDDWILNGSKIWTTGAWWSDWGL
HHCCCHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEECCCEEEECCCCCCCCCE
VLARTNWDVPKHRGLTVFILPIHQPGIEVHRIEMLNGNKEFCQEFLTDVRVPDSDRIGEV
EEEECCCCCCCCCCCEEEEEECCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCC
DDGWTVGTRWMFHERMLHNSPLVTIPADGARGTIRATHLVEIARDAGRLDDPLARDLIGE
CCCCEECHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCC
GRMLDLVTHALQGRLSRGLRSGRMPDQSAAIGRLFTGVTAARTTTLSFNLAGGASAAWTD
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCC
DDGATAECGNDFLLRQVSCIGGGTTEMARNVVSERVLGMPREPAKDRGVAFRDVPRGASN
CCCCCHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHCCCEEECCCCCCCC
RG
CC
>Mature Secondary Structure 
STGDIEDVETFRRRARDWIRANLAPLPAGSGIGVMRAGASDEAELAAVARQREIQRMFF
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHH
DAGFAGIAFPREYGGQGLTPDHQRAFSEEISGYEYPADIQAPTFSPCAAVLLDFGTEEQK
HCCCCCCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCHHH
RQHIPAILKGEELWMQFLSEPSAGSDVAAALTSAVRDGDDWILNGSKIWTTGAWWSDWGL
HHCCCHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEECCCEEEECCCCCCCCCE
VLARTNWDVPKHRGLTVFILPIHQPGIEVHRIEMLNGNKEFCQEFLTDVRVPDSDRIGEV
EEEECCCCCCCCCCCEEEEEECCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCC
DDGWTVGTRWMFHERMLHNSPLVTIPADGARGTIRATHLVEIARDAGRLDDPLARDLIGE
CCCCEECHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCC
GRMLDLVTHALQGRLSRGLRSGRMPDQSAAIGRLFTGVTAARTTTLSFNLAGGASAAWTD
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCC
DDGATAECGNDFLLRQVSCIGGGTTEMARNVVSERVLGMPREPAKDRGVAFRDVPRGASN
CCCCCHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHCCCEEECCCCCCCC
RG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]