Click here to switch to the map view.

The map label for this gene is pgsA2 [H]

Identifier: 158313058

GI number: 158313058

Start: 1442287

End: 1442991

Strand: Direct

Name: pgsA2 [H]

Synonym: Franean1_1206

Alternate gene names: 158313058

Gene position: 1442287-1442991 (Clockwise)

Preceding gene: 158313057

Following gene: 158313059

Centisome position: 16.06

GC content: 72.2

Gene sequence:

>705_bases
GTGACCGGCACCGGCGACCTGGTGGCGCCGAAGCCGCCGGTCCTCAACATCGCGAACATCCTGACGATCATCCGGCTGGC
CCTGGTGCCGGTCTTTGTGGCCTTCCTGTTCGCCGGCCCGGACACCGACGGCTGGCGCTACGCGGCGTTCGGCGCCTACG
CCGTCGCCGCGATCACCGACCAGATCGACGGCTCGATCGCCCGCCGCCGCGGCCTCGTCACCGACTTCGGGATTCTGGTG
GATCCCATCGCGGACAAGGCGCTTACCGGTGCCGCGCTGGTCTCGCTGTCGATCCTCAGTGAACTGCCCTGGGCGGTCAC
CGTCGTGGTCGCCGTCCGCGAGATCGGCGTGACGCTGCTGCGGCTGTGGGTCATCCGGTACGGGGTGATCGCGGCCAGCC
GGGGTGGTAAGGCGAAGACGCTGCTCCTCAACATCTCGCTCGGGCTCTACGTCCTGCCGCTGGAGGGCGTGGCGGCCACG
GGACGGGCGGTGATCCTCGCCTGCGGTGTCGTCGTCGCCGCGGTGACCGGGGCGGACTACGTCTACCGGGCACTGGCGCT
GCGCCGCCGGGCCACCGCGGCGGCCCGGCCGGGCGGCGCTCCCGCCGTGCCGACCCCCGACGTGCCAAACCTGGGCGGGC
CGGCTATGGGTGAGGACCAGGAGGCCGTGACCGGGCCCGGAAGAGGAGAGATCGATGCGCGCTGA

Upstream 100 bases:

>100_bases
GTGCCGGGTCGGTCGGTTCGGCCGGGGCGGGTTCCGTGCTGCCGCCGATCCCGGACGGGGTCGGCCCGATGGACGCGGTG
GGCCACCCTTCGGGCGTGGC

Downstream 100 bases:

>100_bases
GCTGCTGGCGGTGGGGGACGAGCTCCTCTACGGGGACATCGTGAACGGCAACGCGGCCTGGCTGGGACGCCAGCTCGCCG
ACGTCGGGGTCGAGGTGGCG

Product: CDP-alcohol phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MTGTGDLVAPKPPVLNIANILTIIRLALVPVFVAFLFAGPDTDGWRYAAFGAYAVAAITDQIDGSIARRRGLVTDFGILV
DPIADKALTGAALVSLSILSELPWAVTVVVAVREIGVTLLRLWVIRYGVIAASRGGKAKTLLLNISLGLYVLPLEGVAAT
GRAVILACGVVVAAVTGADYVYRALALRRRATAAARPGGAPAVPTPDVPNLGGPAMGEDQEAVTGPGRGEIDAR

Sequences:

>Translated_234_residues
MTGTGDLVAPKPPVLNIANILTIIRLALVPVFVAFLFAGPDTDGWRYAAFGAYAVAAITDQIDGSIARRRGLVTDFGILV
DPIADKALTGAALVSLSILSELPWAVTVVVAVREIGVTLLRLWVIRYGVIAASRGGKAKTLLLNISLGLYVLPLEGVAAT
GRAVILACGVVVAAVTGADYVYRALALRRRATAAARPGGAPAVPTPDVPNLGGPAMGEDQEAVTGPGRGEIDAR
>Mature_233_residues
TGTGDLVAPKPPVLNIANILTIIRLALVPVFVAFLFAGPDTDGWRYAAFGAYAVAAITDQIDGSIARRRGLVTDFGILVD
PIADKALTGAALVSLSILSELPWAVTVVVAVREIGVTLLRLWVIRYGVIAASRGGKAKTLLLNISLGLYVLPLEGVAATG
RAVILACGVVVAAVTGADYVYRALALRRRATAAARPGGAPAVPTPDVPNLGGPAMGEDQEAVTGPGRGEIDAR

Specific function: This Protein Catalyzes The Committed Step To The Synthesis Of The Acidic Phospholipids. [C]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=132, Percent_Identity=39.3939393939394, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 24086; Mature: 23955

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGTGDLVAPKPPVLNIANILTIIRLALVPVFVAFLFAGPDTDGWRYAAFGAYAVAAITD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHH
QIDGSIARRRGLVTDFGILVDPIADKALTGAALVSLSILSELPWAVTVVVAVREIGVTLL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RLWVIRYGVIAASRGGKAKTLLLNISLGLYVLPLEGVAATGRAVILACGVVVAAVTGADY
HHHHHHHHHHEECCCCCEEEEEEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
VYRALALRRRATAAARPGGAPAVPTPDVPNLGGPAMGEDQEAVTGPGRGEIDAR
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCC
>Mature Secondary Structure 
TGTGDLVAPKPPVLNIANILTIIRLALVPVFVAFLFAGPDTDGWRYAAFGAYAVAAITD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHH
QIDGSIARRRGLVTDFGILVDPIADKALTGAALVSLSILSELPWAVTVVVAVREIGVTLL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RLWVIRYGVIAASRGGKAKTLLLNISLGLYVLPLEGVAATGRAVILACGVVVAAVTGADY
HHHHHHHHHHEECCCCCEEEEEEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
VYRALALRRRATAAARPGGAPAVPTPDVPNLGGPAMGEDQEAVTGPGRGEIDAR
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036; 10889206 [H]